Drosophila melanogaster

29 known processes

Karl (Dmel_CG4139)

CG4139 gene product from transcript CG4139-RB

(Aliases: CG4139,Dmel\CG4139,karl)

Karl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell migrationGO:00164772380.057
imaginal disc derived appendage developmentGO:00487373990.050
imaginal disc derived wing morphogenesisGO:00074763370.049
tissue migrationGO:00901301550.044
post embryonic appendage morphogenesisGO:00351203850.043
columnar cuboidal epithelial cell developmentGO:00020662490.043
epithelial cell developmentGO:00020642740.038
endocytosisGO:00068973100.038
columnar cuboidal epithelial cell differentiationGO:00020652560.038
ameboidal type cell migrationGO:00016671510.038
response to organic substanceGO:00100332840.038
vesicle mediated transportGO:00161923810.035
response to abiotic stimulusGO:00096283410.035
imaginal disc derived appendage morphogenesisGO:00351143950.033
response to external biotic stimulusGO:00432072930.033
epithelial cell differentiationGO:00308553220.031
appendage morphogenesisGO:00351073970.030
ovarian follicle cell developmentGO:00307072480.029
response to extracellular stimulusGO:00099911160.028
response to biotic stimulusGO:00096072940.026
appendage developmentGO:00487364010.026
regionalizationGO:00030024160.025
wing disc morphogenesisGO:00074723440.024
response to lipopolysaccharideGO:003249640.023
positive regulation of response to stimulusGO:00485843230.023
phagocytosisGO:00069092150.023
body morphogenesisGO:001017120.023
cell proliferationGO:00082832990.022
regulation of multicellular organismal developmentGO:20000264140.022
protein modification processGO:00362114380.022
catabolic processGO:00090564090.022
neurological system processGO:00508773580.022
immune system processGO:00023763470.022
regulation of catalytic activityGO:00507901850.022
regulation of localizationGO:00328792750.022
camera type eye developmentGO:004301040.021
growthGO:00400073590.021
eye developmentGO:00016543230.021
positive regulation of signalingGO:00230562430.021
organonitrogen compound metabolic processGO:19015643180.021
axon guidanceGO:00074112330.021
negative regulation of gene expressionGO:00106293870.021
positive regulation of signal transductionGO:00099672230.021
hormone catabolic processGO:004244730.021
epithelium migrationGO:00901321480.020
single organism behaviorGO:00447083910.020
forebrain developmentGO:003090020.020
developmental growthGO:00485892800.020
tube morphogenesisGO:00352391910.020
deathGO:00162652840.020
response to oxygen containing compoundGO:19017002000.020
negative regulation of cellular metabolic processGO:00313243820.019
regulation of protein metabolic processGO:00512462560.019
small gtpase mediated signal transductionGO:0007264880.019
carbohydrate derivative metabolic processGO:19011352170.019
localization of cellGO:00516742570.019
actin filament based processGO:00300292200.019
regulation of intracellular signal transductionGO:19025312360.019
cell motilityGO:00488702510.018
positive regulation of cell communicationGO:00106472500.018
positive regulation of biosynthetic processGO:00098913160.018
ovarian follicle cell migrationGO:00072971210.018
amine metabolic processGO:0009308120.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
compound eye morphogenesisGO:00017452490.018
regulation of cell differentiationGO:00455953020.018
organic substance catabolic processGO:19015753080.018
positive regulation of nitrogen compound metabolic processGO:00511733540.017
positive regulation of cellular biosynthetic processGO:00313283160.017
proteolysisGO:00065081920.017
compound eye developmentGO:00487493070.017
ras protein signal transductionGO:0007265880.017
cellular protein modification processGO:00064644380.017
tissue morphogenesisGO:00487292970.017
defense response to bacteriumGO:00427421780.017
connective tissue developmentGO:006144830.017
intracellular signal transductionGO:00355563000.016
cellular response to chemical stimulusGO:00708871990.016
regulation of molecular functionGO:00650092170.016
response to other organismGO:00517072930.016
cellular amino acid metabolic processGO:0006520610.016
cellular ketone metabolic processGO:0042180240.016
mesodermal cell migrationGO:000807870.016
small molecule metabolic processGO:00442813050.016
segmentationGO:00352822070.016
regulation of anatomical structure sizeGO:00900661630.016
germarium derived egg chamber formationGO:00072931010.016
central nervous system developmentGO:00074172010.016
taxisGO:00423303040.016
response to nutrient levelsGO:00316671140.016
lateral inhibitionGO:00463312060.016
organic substance transportGO:00717022570.016
chemotaxisGO:00069352490.016
oxoacid metabolic processGO:00434361030.015
gland morphogenesisGO:00226121450.015
actin filament based movementGO:0030048260.015
morphogenesis of an epitheliumGO:00020092760.015
defense responseGO:00069523000.015
regulation of cellular amine metabolic processGO:003323830.015
phosphorylationGO:00163102940.015
response to alcoholGO:0097305950.015
response to starvationGO:0042594970.015
regulation of cell deathGO:00109411730.015
transcription from rna polymerase ii promoterGO:00063663680.015
regulation of anatomical structure morphogenesisGO:00226032420.015
regulation of cellular protein metabolic processGO:00322682430.015
single organism intracellular transportGO:19025822070.015
gastrulationGO:0007369700.015
negative regulation of cell communicationGO:00106482230.015
gene silencingGO:00164581380.015
salivary gland developmentGO:00074311620.015
cellular catabolic processGO:00442483720.015
regulation of cellular ketone metabolic processGO:001056530.015
multi organism behaviorGO:00517051750.015
cellular amine metabolic processGO:0044106120.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.014
benzene containing compound metabolic processGO:004253730.014
positive regulation of cell migrationGO:003033520.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
regulation of response to external stimulusGO:00321011150.014
secondary metabolic processGO:0019748750.014
organelle fissionGO:00482853400.014
negative regulation of response to stimulusGO:00485852580.014
spindle organizationGO:00070512530.014
xenobiotic catabolic processGO:004217810.014
digestive tract developmentGO:00485651490.014
regulation of cell cycleGO:00517262910.014
androgen metabolic processGO:000820910.014
regulation of multi organism processGO:00439001310.014
single organism catabolic processGO:00447122280.014
eye morphogenesisGO:00485922600.014
positive regulation of nucleobase containing compound metabolic processGO:00459353320.014
regulation of immune system processGO:00026821760.013
gland developmentGO:00487321910.013
regulation of apoptotic processGO:00429811300.013
negative regulation of signalingGO:00230572190.013
negative regulation of signal transductionGO:00099682060.013
axonogenesisGO:00074092900.013
positive regulation of gene expressionGO:00106282900.013
inter male aggressive behaviorGO:0002121600.013
carbohydrate metabolic processGO:0005975820.013
sensory perceptionGO:00076001960.013
sensory organ morphogenesisGO:00905962600.013
actin cytoskeleton organizationGO:00300362060.013
regulation of cell cycle processGO:00105641810.013
telencephalon developmentGO:002153720.013
nuclear divisionGO:00002803320.013
exocrine system developmentGO:00352721620.013
positive regulation of transcription dna templatedGO:00458932660.013
retina development in camera type eyeGO:006004140.013
transmembrane transportGO:00550851390.013
regulation of cellular component biogenesisGO:00440872010.013
positive regulation of cell motilityGO:200014730.013
regulation of programmed cell deathGO:00430671520.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
neuron projection guidanceGO:00974852410.013
digestive system developmentGO:00551231490.013
negative regulation of multicellular organismal processGO:00512411420.013
negative regulation of developmental processGO:00510932010.013
heterocycle catabolic processGO:00467001660.013
tissue deathGO:00162711020.013
aromatic compound catabolic processGO:00194391660.013
positive regulation of macromolecule biosynthetic processGO:00105572830.012
steroid catabolic processGO:000670610.012
cation transportGO:00068121100.012
regulation of nervous system developmentGO:00519602480.012
actin mediated cell contractionGO:0070252210.012
regulation of response to stressGO:00801342000.012
cellular response to organic substanceGO:00713101320.012
lipid metabolic processGO:00066291210.012
regulation of developmental growthGO:00486381740.012
establishment of localization in cellGO:00516494020.012
regulation of organelle organizationGO:00330431960.012
macromolecule catabolic processGO:00090571610.012
cellular response to dna damage stimulusGO:00069742230.012
immune responseGO:00069552460.012
dna metabolic processGO:00062592270.012
sterol homeostasisGO:005509240.012
blastoderm segmentationGO:00073501590.012
defense response to other organismGO:00985422250.012
positive regulation of rna metabolic processGO:00512542710.012
ethanolamine containing compound metabolic processGO:004243940.012
regulation of phosphorus metabolic processGO:00511742100.012
matingGO:00076181200.012
regulation of mitotic cell cycleGO:00073461900.012
positive regulation of phosphate metabolic processGO:00459371390.012
embryonic pattern specificationGO:00098801740.012
single organism biosynthetic processGO:00447112060.012
cell deathGO:00082192790.012
organic cyclic compound catabolic processGO:19013611680.012
response to heatGO:0009408630.012
intracellular transportGO:00469072280.012
synaptic transmissionGO:00072682880.012
digestive tract morphogenesisGO:00485461270.012
cellular macromolecule catabolic processGO:00442651360.012
actin filament organizationGO:00070151260.012
negative regulation of macromolecule biosynthetic processGO:00105582700.011
response to bacteriumGO:00096171980.011
positive regulation of developmental processGO:00510941430.011
multicellular organismal agingGO:00102591400.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
regulation of cell projection organizationGO:0031344920.011
aggressive behaviorGO:0002118630.011
multi multicellular organism processGO:00447061230.011
salivary gland morphogenesisGO:00074351450.011
adult behaviorGO:00305341370.011
positive regulation of rna biosynthetic processGO:19026802660.011
negative regulation of cell differentiationGO:00455961430.011
chromatin organizationGO:00063252070.011
regulation of gene expression epigeneticGO:00400291280.011
cellular response to biotic stimulusGO:007121640.011
regulation of hydrolase activityGO:0051336970.011
negative regulation of rna metabolic processGO:00512532510.011
ion transportGO:00068111450.011
protein localizationGO:00081042840.011
programmed cell deathGO:00125012570.011
response to organophosphorusGO:004668320.011
response to temperature stimulusGO:00092661060.011
response to organic cyclic compoundGO:0014070890.011
multi organism reproductive behaviorGO:00447051210.011
single organism carbohydrate metabolic processGO:0044723720.011
macromolecular complex assemblyGO:00650032560.011
protein hydroxylationGO:001812610.011
cellular response to lipopolysaccharideGO:007122230.010
male gamete generationGO:00482322010.010
apoptotic processGO:00069151590.010
response to endogenous stimulusGO:00097191190.010
protein phosphorylationGO:00064681690.010
regulation of cellular catabolic processGO:00313291570.010
establishment of synaptic vesicle localizationGO:0097480500.010
chaeta developmentGO:0022416970.010
regulation of cell proliferationGO:00421271630.010
cell cycle checkpointGO:0000075950.010
cellular response to molecule of bacterial originGO:007121930.010
embryonic development via the syncytial blastodermGO:00017001480.010
cell recognitionGO:00080371020.010
organic acid metabolic processGO:00060821030.010
developmental maturationGO:00217001720.010
nucleobase containing compound catabolic processGO:00346551650.010
signal transduction by phosphorylationGO:00230141070.010
estrogen metabolic processGO:000821010.010
dendrite morphogenesisGO:00488131990.010
regulation of phosphate metabolic processGO:00192202100.010
mitotic cell cycle phase transitionGO:00447721380.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
chromosome organizationGO:00512763600.010
brain developmentGO:00074201200.010
cell cycle phase transitionGO:00447701400.010
salivary gland histolysisGO:0035070880.010
regulation of ras protein signal transductionGO:0046578930.010
intracellular protein transportGO:00068861040.010
open tracheal system developmentGO:00074242040.010
establishment of protein localizationGO:00451841630.010
agingGO:00075681430.010

Karl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.014
disease of metabolismDOID:001466700.014
musculoskeletal system diseaseDOID:1700.013
inherited metabolic disorderDOID:65500.013
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.010
eye diseaseDOID:561400.010