Drosophila melanogaster

0 known processes

Npc2d (Dmel_CG12813)

Niemann-Pick type C-2d

(Aliases: CG12813,Dmel\CG12813,npc2d)

Npc2d biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cell signaling involved in cell fate commitmentGO:00451682100.085
lateral inhibitionGO:00463312060.054
endocytosisGO:00068973100.042
vesicle mediated transportGO:00161923810.039
appendage morphogenesisGO:00351073970.037
protein modification processGO:00362114380.035
small molecule metabolic processGO:00442813050.035
Fly
phagocytosisGO:00069092150.031
response to external biotic stimulusGO:00432072930.031
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.028
wing disc morphogenesisGO:00074723440.028
body morphogenesisGO:001017120.028
appendage developmentGO:00487364010.028
organic substance transportGO:00717022570.028
Fly
imaginal disc derived appendage developmentGO:00487373990.027
imaginal disc derived wing morphogenesisGO:00074763370.027
cellular protein modification processGO:00064644380.026
response to abiotic stimulusGO:00096283410.026
cholesterol homeostasisGO:004263230.026
post embryonic appendage morphogenesisGO:00351203850.025
cellular amine metabolic processGO:0044106120.025
single organism behaviorGO:00447083910.024
catabolic processGO:00090564090.024
response to organic substanceGO:00100332840.024
organic acid metabolic processGO:00060821030.024
response to lipopolysaccharideGO:003249640.023
camera type eye developmentGO:004301040.023
phosphorylationGO:00163102940.023
oxoacid metabolic processGO:00434361030.023
negative regulation of gene expressionGO:00106293870.022
organonitrogen compound metabolic processGO:19015643180.022
cell proliferationGO:00082832990.022
carboxylic acid metabolic processGO:0019752920.022
regulation of response to stressGO:00801342000.021
immune responseGO:00069552460.021
Fly
homeostatic processGO:00425921990.021
Fly
positive regulation of response to stimulusGO:00485843230.021
regulation of cellular ketone metabolic processGO:001056530.021
regulation of localizationGO:00328792750.021
proteolysisGO:00065081920.020
regionalizationGO:00030024160.020
deathGO:00162652840.020
positive regulation of signalingGO:00230562430.020
rna localizationGO:00064031150.020
single organism biosynthetic processGO:00447112060.020
Fly
positive regulation of signal transductionGO:00099672230.019
establishment of localization in cellGO:00516494020.019
positive regulation of cell communicationGO:00106472500.019
intracellular signal transductionGO:00355563000.019
regulation of cellular amine metabolic processGO:003323830.018
forebrain developmentGO:003090020.018
positive regulation of nitrogen compound metabolic processGO:00511733540.018
organic substance catabolic processGO:19015753080.018
cellular catabolic processGO:00442483720.018
positive regulation of cellular biosynthetic processGO:00313283160.018
response to oxygen containing compoundGO:19017002000.018
immune system processGO:00023763470.018
Fly
cell deathGO:00082192790.018
regulation of multicellular organismal developmentGO:20000264140.018
localization of cellGO:00516742570.018
regulation of cellular amino acid metabolic processGO:000652100.018
lipid metabolic processGO:00066291210.017
Fly
hormone catabolic processGO:004244730.017
response to biotic stimulusGO:00096072940.017
Fly
cellular response to dna damage stimulusGO:00069742230.017
macromolecular complex assemblyGO:00650032560.017
response to alcoholGO:0097305950.017
regulation of cell cycleGO:00517262910.017
cellular amino acid metabolic processGO:0006520610.017
amine metabolic processGO:0009308120.016
cell motilityGO:00488702510.016
defense responseGO:00069523000.016
Fly
protein maturationGO:0051604710.016
organelle fissionGO:00482853400.016
benzene containing compound metabolic processGO:004253730.016
regulation of transportGO:00510491810.016
connective tissue developmentGO:006144830.016
sterol homeostasisGO:005509240.016
Fly
regulation of cellular protein metabolic processGO:00322682430.016
nuclear divisionGO:00002803320.016
negative regulation of cellular metabolic processGO:00313243820.015
positive regulation of biosynthetic processGO:00098913160.015
carbohydrate derivative metabolic processGO:19011352170.015
response to extracellular stimulusGO:00099911160.015
regulation of phosphorus metabolic processGO:00511742100.015
protein localizationGO:00081042840.015
transcription from rna polymerase ii promoterGO:00063663680.015
response to hexoseGO:000974630.015
cellular macromolecule localizationGO:00707272200.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
camera type eye morphogenesisGO:004859320.015
cell migrationGO:00164772380.015
telencephalon developmentGO:002153720.015
negative regulation of signalingGO:00230572190.015
chemical homeostasisGO:0048878920.015
Fly
adult behaviorGO:00305341370.014
mitotic nuclear divisionGO:00070672130.014
negative regulation of signal transductionGO:00099682060.014
intracellular transportGO:00469072280.014
regulation of molecular functionGO:00650092170.014
regulation of protein metabolic processGO:00512462560.014
response to monosaccharideGO:003428440.014
agingGO:00075681430.014
regulation of cell differentiationGO:00455953020.014
organophosphate metabolic processGO:00196371950.014
multicellular organismal agingGO:00102591400.014
negative regulation of cell communicationGO:00106482230.014
single organism intracellular transportGO:19025822070.014
developmental maturationGO:00217001720.014
actin filament based processGO:00300292200.014
androgen metabolic processGO:000820910.014
single organism catabolic processGO:00447122280.014
limb developmentGO:006017310.014
regulation of intracellular signal transductionGO:19025312360.014
segmentationGO:00352822070.014
gland developmentGO:00487321910.014
programmed cell deathGO:00125012570.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
regulation of cell deathGO:00109411730.013
taxisGO:00423303040.013
kidney developmentGO:000182230.013
regulation of catabolic processGO:00098941700.013
protein complex biogenesisGO:00702712010.013
response to nutrient levelsGO:00316671140.013
chaeta developmentGO:0022416970.013
immune response activating signal transductionGO:000275720.013
protein phosphorylationGO:00064681690.013
negative regulation of biosynthetic processGO:00098902770.013
chromosome organizationGO:00512763600.013
developmental growthGO:00485892800.013
cholesterol transportGO:003030120.013
glycerolipid catabolic processGO:004650330.013
negative regulation of cellular biosynthetic processGO:00313272770.013
aromatic compound catabolic processGO:00194391660.013
eye developmentGO:00016543230.013
immune response regulating signaling pathwayGO:000276420.013
nitrogen compound transportGO:0071705850.013
compound eye developmentGO:00487493070.013
response to copper ionGO:004668840.012
antimicrobial humoral responseGO:0019730990.012
regulation of cellular response to stressGO:0080135890.012
positive regulation of cellular amine metabolic processGO:003324000.012
protein processingGO:0016485680.012
cell divisionGO:00513012480.012
developmental programmed cell deathGO:00106231380.012
synaptic transmissionGO:00072682880.012
negative regulation of nucleic acid templated transcriptionGO:19035072400.012
regulation of phosphate metabolic processGO:00192202100.012
cellular ketone metabolic processGO:0042180240.012
Fly
regulation of anatomical structure morphogenesisGO:00226032420.012
regulation of cellular catabolic processGO:00313291570.012
positive regulation of macromolecule metabolic processGO:00106044050.012
activation of innate immune responseGO:000221840.012
multi organism behaviorGO:00517051750.012
regulation of lipid transportGO:003236830.012
macromolecule catabolic processGO:00090571610.012
hindbrain developmentGO:003090220.012
regulation of programmed cell deathGO:00430671520.012
dorsal ventral pattern formationGO:00099531330.012
response to woundingGO:0009611940.012
Fly
compound eye morphogenesisGO:00017452490.012
cellular response to organic substanceGO:00713101320.012
response to glucoseGO:000974920.012
response to bacteriumGO:00096171980.012
Fly
regulation of catalytic activityGO:00507901850.012
posttranscriptional regulation of gene expressionGO:00106081450.012
acylglycerol catabolic processGO:004646430.012
nucleobase containing compound transportGO:0015931560.012
regulation of sequestering of triglycerideGO:001088930.012
ethanolamine containing compound metabolic processGO:004243940.012
mesenchymal cell differentiationGO:004876210.011
limb morphogenesisGO:003510810.011
negative regulation of response to stimulusGO:00485852580.011
positive regulation of cell motilityGO:200014730.011
establishment of rna localizationGO:0051236470.011
nephron tubule developmentGO:007208030.011
growthGO:00400073590.011
matingGO:00076181200.011
monocarboxylic acid transportGO:001571830.011
positive regulation of multicellular organismal processGO:00512401430.011
actin cytoskeleton organizationGO:00300362060.011
response to starvationGO:0042594970.011
rna processingGO:00063961470.011
axon developmentGO:00615642970.011
negative regulation of developmental processGO:00510932010.011
regulation of organelle organizationGO:00330431960.011
cellular protein localizationGO:00346131600.011
defense response to bacteriumGO:00427421780.011
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.011
response to endogenous stimulusGO:00097191190.011
cellular macromolecule catabolic processGO:00442651360.011
transmembrane transportGO:00550851390.011
endomembrane system organizationGO:00102561190.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
signal transduction by phosphorylationGO:00230141070.011
eye morphogenesisGO:00485922600.011
positive regulation of cell migrationGO:003033520.011
protein complex assemblyGO:00064612000.011
phospholipid homeostasisGO:005509110.011
axis specificationGO:00097981670.011
retina development in camera type eyeGO:006004140.011
regulation of multi organism processGO:00439001310.011
response to radiationGO:00093141550.011
small gtpase mediated signal transductionGO:0007264880.011
neutral lipid catabolic processGO:004646130.011
chromosome segregationGO:00070591570.011
acylglycerol biosynthetic processGO:004646320.011
wound healingGO:0042060750.011
Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
embryonic pattern specificationGO:00098801740.011
mitotic cell cycle phase transitionGO:00447721380.011
response to organophosphorusGO:004668320.011
embryonic axis specificationGO:00005781070.011
cellular response to chemical stimulusGO:00708871990.011
blastoderm segmentationGO:00073501590.011
anterior posterior pattern specificationGO:00099521360.011
regulation of cell substrate adhesionGO:001081020.011
epithelial cell developmentGO:00020642740.011
response to organic cyclic compoundGO:0014070890.011
regulation of apoptotic processGO:00429811300.011
epithelial cell differentiationGO:00308553220.011
humoral immune responseGO:00069591170.011
Fly
gene silencingGO:00164581380.010
determination of adult lifespanGO:00083401370.010
mesenchymal cell developmentGO:001403110.010
positive regulation of rna biosynthetic processGO:19026802660.010
pyridine containing compound metabolic processGO:007252430.010
cellularizationGO:0007349900.010
ameboidal type cell migrationGO:00016671510.010
regulation of epithelial cell proliferationGO:005067840.010
neuron projection guidanceGO:00974852410.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
cell cycle phase transitionGO:00447701400.010
ras protein signal transductionGO:0007265880.010
apoptotic processGO:00069151590.010
organophosphate catabolic processGO:00464341120.010
negative regulation of cell differentiationGO:00455961430.010
positive regulation of rna metabolic processGO:00512542710.010
cellular response to carbohydrate stimulusGO:007132240.010
carbohydrate derivative biosynthetic processGO:1901137850.010
chemotaxisGO:00069352490.010
exocrine system developmentGO:00352721620.010
organic cyclic compound catabolic processGO:19013611680.010
regulation of transcription from rna polymerase ii promoterGO:00063573780.010
cell maturationGO:00484691440.010
kidney morphogenesisGO:006099330.010

Npc2d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
disease of metabolismDOID:001466700.022
nervous system diseaseDOID:86300.020
inherited metabolic disorderDOID:65500.019
musculoskeletal system diseaseDOID:1700.013
sensory system diseaseDOID:005015500.012
hypophosphatasiaDOID:1421300.012
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011