Drosophila melanogaster

7 known processes

sle (Dmel_CG12819)

slender lobes

(Aliases: CG12819,Dmel\CG12819,CG12819-PA)

sle biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle fissionGO:00482853400.975
brain developmentGO:00074201200.899
mushroom body developmentGO:0016319700.867
central nervous system developmentGO:00074172010.723
head developmentGO:00603221350.691
neural precursor cell proliferationGO:0061351750.542
negative regulation of biosynthetic processGO:00098902770.542
macromolecular complex assemblyGO:00650032560.433
cell proliferationGO:00082832990.418
ribonucleoside monophosphate catabolic processGO:0009158390.410
atp metabolic processGO:0046034490.403
asymmetric neuroblast divisionGO:0055059330.388
dna metabolic processGO:00062592270.376
mitotic nuclear divisionGO:00070672130.375
purine ribonucleoside monophosphate catabolic processGO:0009169380.373
chromosome segregationGO:00070591570.297
chromosome organizationGO:00512763600.289
agingGO:00075681430.272
nucleosome organizationGO:0034728590.265
purine nucleoside monophosphate catabolic processGO:0009128380.230
regulation of chromosome segregationGO:0051983320.227
negative regulation of cellular metabolic processGO:00313243820.194
cell deathGO:00082192790.192
nucleoside phosphate metabolic processGO:00067531620.187
ribonucleoside monophosphate metabolic processGO:0009161510.177
mitotic cell cycle phase transitionGO:00447721380.169
multicellular organismal agingGO:00102591400.163
glycosyl compound metabolic processGO:19016571270.163
regulation of cellular component biogenesisGO:00440872010.151
dna repairGO:0006281540.142
purine ribonucleoside monophosphate metabolic processGO:0009167500.141
nucleobase containing small molecule metabolic processGO:00550861740.138
mitotic cell cycle checkpointGO:0007093880.133
spindle organizationGO:00070512530.130
protein modification processGO:00362114380.127
chromatin assemblyGO:0031497480.127
mitotic spindle organizationGO:00070522200.127
programmed cell deathGO:00125012570.125
cellular protein modification processGO:00064644380.122
carbohydrate derivative metabolic processGO:19011352170.120
response to oxygen containing compoundGO:19017002000.120
regulation of apoptotic processGO:00429811300.119
organelle assemblyGO:00709251980.119
mitotic sister chromatid segregationGO:0000070870.118
glycosyl compound catabolic processGO:19016581120.118
nucleoside monophosphate catabolic processGO:0009125390.114
chromosome separationGO:0051304420.113
deathGO:00162652840.112
determination of adult lifespanGO:00083401370.112
nucleoside catabolic processGO:00091641120.110
organonitrogen compound metabolic processGO:19015643180.109
male gamete generationGO:00482322010.109
purine nucleoside monophosphate metabolic processGO:0009126500.108
sister chromatid segregationGO:0000819920.104
ribonucleoside metabolic processGO:00091191270.101
regulation of cell cycle phase transitionGO:19019871300.099
purine nucleoside catabolic processGO:00061521120.094
ribonucleotide metabolic processGO:00092591450.094
purine ribonucleoside triphosphate catabolic processGO:00092071080.091
vesicle mediated transportGO:00161923810.090
negative regulation of gene expressionGO:00106293870.089
response to light stimulusGO:00094161240.086
protein localizationGO:00081042840.085
cellular catabolic processGO:00442483720.083
ribonucleoside triphosphate catabolic processGO:00092031080.083
nucleoside phosphate catabolic processGO:19012921100.083
small molecule metabolic processGO:00442813050.082
response to radiationGO:00093141550.077
organonitrogen compound catabolic processGO:19015651280.075
maintenance of protein locationGO:0045185280.073
regulation of mitotic cell cycleGO:00073461900.072
embryo development ending in birth or egg hatchingGO:00097921520.072
cellular protein complex assemblyGO:0043623710.070
nucleus organizationGO:0006997450.069
maintenance of protein location in cellGO:0032507260.068
cellular response to dna damage stimulusGO:00069742230.068
maintenance of location in cellGO:0051651280.068
ribonucleoside catabolic processGO:00424541120.067
negative regulation of mitotic cell cycleGO:00459301090.066
rna processingGO:00063961470.065
centrosome cycleGO:00070981370.065
nucleoside triphosphate catabolic processGO:00091431080.062
organophosphate metabolic processGO:00196371950.061
response to abiotic stimulusGO:00096283410.059
mitotic g2 dna damage checkpointGO:0007095690.059
carbohydrate derivative catabolic processGO:19011361180.059
development of primary sexual characteristicsGO:0045137500.059
cellular nitrogen compound catabolic processGO:00442701650.059
regulation of cell deathGO:00109411730.058
regulation of cell cycleGO:00517262910.058
imaginal disc derived appendage morphogenesisGO:00351143950.058
purine nucleotide metabolic processGO:00061631460.057
purine ribonucleoside triphosphate metabolic processGO:00092051190.057
forebrain developmentGO:003090020.057
purine nucleoside triphosphate catabolic processGO:00091461080.056
dna integrity checkpointGO:0031570810.056
cell divisionGO:00513012480.056
nucleoside metabolic processGO:00091161270.055
ubiquitin dependent protein catabolic processGO:0006511780.055
apoptotic processGO:00069151590.054
chromatin remodelingGO:0006338720.054
cellular macromolecule localizationGO:00707272200.054
regulation of mitotic sister chromatid segregationGO:0033047280.053
cell cycle checkpointGO:0000075950.053
cellular macromolecular complex assemblyGO:00346221530.053
meiotic cell cycleGO:00513211710.053
catabolic processGO:00090564090.053
multi organism behaviorGO:00517051750.053
localization of cellGO:00516742570.053
endocytosisGO:00068973100.052
nucleotide catabolic processGO:00091661090.051
positive regulation of multicellular organismal processGO:00512401430.051
purine nucleoside metabolic processGO:00422781270.050
purine ribonucleotide metabolic processGO:00091501450.050
heterocycle catabolic processGO:00467001660.050
organic substance catabolic processGO:19015753080.050
stem cell proliferationGO:0072089880.049
morphogenesis of an epitheliumGO:00020092760.049
negative regulation of mitotic cell cycle phase transitionGO:19019911030.048
response to temperature stimulusGO:00092661060.047
maintenance of locationGO:0051235730.045
nucleocytoplasmic transportGO:0006913720.044
regulation of sister chromatid segregationGO:0033045280.044
response to organic substanceGO:00100332840.044
body morphogenesisGO:001017120.043
multi multicellular organism processGO:00447061230.043
imaginal disc derived appendage developmentGO:00487373990.042
negative regulation of nitrogen compound metabolic processGO:00511722650.041
positive regulation of cell deathGO:0010942690.041
nuclear divisionGO:00002803320.040
metaphase anaphase transition of mitotic cell cycleGO:0007091280.040
mitotic g2 m transition checkpointGO:0044818700.040
regulation of chromosome organizationGO:0033044640.039
retina development in camera type eyeGO:006004140.039
spindle assembly checkpointGO:0071173110.039
negative regulation of protein metabolic processGO:0051248850.038
single organism catabolic processGO:00447122280.037
purine ribonucleoside catabolic processGO:00461301120.037
regulation of localizationGO:00328792750.036
axon developmentGO:00615642970.036
nucleoside monophosphate metabolic processGO:0009123520.036
nucleoside triphosphate metabolic processGO:00091411200.035
purine nucleoside triphosphate metabolic processGO:00091441190.035
regulation of hydrolase activityGO:0051336970.034
ribose phosphate metabolic processGO:00196931450.034
sex differentiationGO:0007548810.034
ribonucleotide catabolic processGO:00092611090.034
matingGO:00076181200.034
aromatic compound catabolic processGO:00194391660.033
regulation of protein metabolic processGO:00512462560.033
chromatin assembly or disassemblyGO:0006333520.032
positive regulation of programmed cell deathGO:0043068620.032
regulation of programmed cell deathGO:00430671520.032
response to organic cyclic compoundGO:0014070890.032
protein import into nucleusGO:0006606510.032
nucleosome positioningGO:001658430.032
mitotic dna integrity checkpointGO:0044774750.032
regulation of metaphase anaphase transition of cell cycleGO:1902099260.031
protein complex biogenesisGO:00702712010.031
single organism nuclear importGO:1902593510.031
ribonucleoside triphosphate metabolic processGO:00091991190.031
reproductive system developmentGO:0061458740.031
cellular protein localizationGO:00346131600.030
protein complex assemblyGO:00064612000.030
cellular component disassemblyGO:0022411460.030
nuclear body organizationGO:003057560.030
camera type eye developmentGO:004301040.029
asymmetric stem cell divisionGO:0098722490.029
regulation of organelle organizationGO:00330431960.029
regulation of phosphorus metabolic processGO:00511742100.029
organophosphate catabolic processGO:00464341120.029
response to external biotic stimulusGO:00432072930.029
eye developmentGO:00016543230.028
dna conformation changeGO:00711031050.028
negative regulation of cellular biosynthetic processGO:00313272770.028
regulation of protein localizationGO:0032880760.028
cytoplasmic microtubule organizationGO:0031122220.028
protein processingGO:0016485680.028
microtubule cytoskeleton organization involved in mitosisGO:1902850520.028
mitotic dna damage checkpointGO:0044773740.027
purine nucleotide catabolic processGO:00061951090.027
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.027
cellular response to chemical stimulusGO:00708871990.026
negative regulation of proteolysisGO:0045861310.026
proteolysis involved in cellular protein catabolic processGO:0051603830.026
positive regulation of rna biosynthetic processGO:19026802660.026
purine containing compound catabolic processGO:00725231120.025
reproductive behaviorGO:00190981220.025
protein localization to nucleusGO:0034504550.025
dna damage checkpointGO:0000077780.025
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.024
regulation of protein complex assemblyGO:0043254420.024
purine ribonucleotide catabolic processGO:00091541090.023
mitotic sister chromatid separationGO:0051306300.023
negative regulation of cellular component organizationGO:00511291080.023
centrosome organizationGO:00512971630.023
cell migrationGO:00164772380.023
negative regulation of response to external stimulusGO:0032102220.022
regulation of mitotic metaphase anaphase transitionGO:0030071260.022
neuronal stem cell divisionGO:0036445350.021
metaphase anaphase transition of cell cycleGO:0044784280.020
modification dependent protein catabolic processGO:0019941780.020
organic cyclic compound catabolic processGO:19013611680.020
atp catabolic processGO:0006200380.019
negative regulation of mitotic sister chromatid separationGO:2000816130.019
negative regulation of cellular protein metabolic processGO:0032269850.019
ribonucleoprotein complex assemblyGO:0022618230.019
nuclear transportGO:0051169720.019
negative regulation of proteasomal protein catabolic processGO:1901799160.019
phagocytosisGO:00069092150.019
positive regulation of cellular biosynthetic processGO:00313283160.018
exocrine system developmentGO:00352721620.018
regulation of protein processingGO:0070613320.018
intracellular protein transportGO:00068861040.018
nucleotide metabolic processGO:00091171610.017
negative regulation of cell deathGO:0060548810.017
regulation of nuclear divisionGO:0051783580.017
negative regulation of cell differentiationGO:00455961430.017
cellular response to nitrogen compoundGO:1901699510.017
positive regulation of cell developmentGO:0010720610.017
cell motilityGO:00488702510.017
homeostatic processGO:00425921990.017
protein importGO:0017038550.016
regulation of establishment of protein localizationGO:0070201610.016
negative regulation of developmental processGO:00510932010.016
microtubule bundle formationGO:0001578270.016
response to uvGO:0009411240.016
positive regulation of developmental processGO:00510941430.016
protein transportGO:00150311550.016
negative regulation of neuron deathGO:1901215180.016
regulation of cellular response to stressGO:0080135890.016
double strand break repairGO:0006302260.016
gonad developmentGO:0008406500.015
purine ribonucleoside metabolic processGO:00461281270.015
spermatogenesisGO:00072832000.015
dna packagingGO:0006323910.015
negative regulation of organelle organizationGO:0010639560.015
proteolysisGO:00065081920.015
centrosome duplicationGO:00512981210.015
salivary gland developmentGO:00074311620.015
asymmetric cell divisionGO:0008356370.014
chemotaxisGO:00069352490.014
positive regulation of cell proliferationGO:0008284470.014
dna duplex unwindingGO:0032508160.014
negative regulation of cell cycleGO:00457861160.014
regulation of multi organism processGO:00439001310.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
multi organism reproductive behaviorGO:00447051210.013
protein dna complex subunit organizationGO:0071824860.013
salivary gland morphogenesisGO:00074351450.013
establishment of localization in cellGO:00516494020.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
tissue morphogenesisGO:00487292970.012
response to biotic stimulusGO:00096072940.012
response to other organismGO:00517072930.012
reproductive structure developmentGO:0048608740.012
regulation of meiosisGO:004002030.012
spindle assemblyGO:0051225800.012
somatic stem cell divisionGO:0048103370.012
negative regulation of chromosome segregationGO:0051985140.012
cell agingGO:000756920.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.012
regulation of cell cycle processGO:00105641810.012
post embryonic appendage morphogenesisGO:00351203850.012
nucleobase containing compound catabolic processGO:00346551650.012
regulation of neuron differentiationGO:00456641030.012
chromatin modificationGO:00165681470.012
centriole replicationGO:0007099240.012
negative regulation of programmed cell deathGO:0043069720.012
cytoplasmic transportGO:00164821300.011
regulation of cell differentiationGO:00455953020.011
developmental programmed cell deathGO:00106231380.011
stem cell divisionGO:0017145690.011
regulation of cell developmentGO:00602842150.011
positive regulation of phosphate metabolic processGO:00459371390.011
multicellular organismal reproductive behaviorGO:00330571100.011
rna splicingGO:0008380830.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
regulation of cellular catabolic processGO:00313291570.011
protein phosphorylationGO:00064681690.011
positive regulation of nitrogen compound metabolic processGO:00511733540.011
chromatin organizationGO:00063252070.011
negative regulation of protein maturationGO:1903318310.011
regulation of molecular functionGO:00650092170.010
protein ubiquitinationGO:0016567700.010
purine containing compound metabolic processGO:00725211550.010
cellular macromolecule catabolic processGO:00442651360.010
regulation of catabolic processGO:00098941700.010
regulation of response to stressGO:00801342000.010
negative regulation of rna metabolic processGO:00512532510.010
regulation of proteolysisGO:0030162870.010
positive regulation of bindingGO:005109940.010
negative regulation of catabolic processGO:0009895360.010
nuclear importGO:0051170510.010

sle disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.010