Drosophila melanogaster

67 known processes

MAPk-Ak2 (Dmel_CG3086)

MAP kinase activated protein-kinase-2

(Aliases: DmMAPKAPK-2,MAPKAP,MAPKAPK-2,CG3086,Dmel\CG3086,MK2)

MAPk-Ak2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transmembrane transportGO:00342201220.414
transmembrane transportGO:00550851390.359
membrane fusionGO:0061025420.256
single organism membrane fusionGO:0044801420.239
neurological system processGO:00508773580.202
axonogenesisGO:00074092900.172
membrane organizationGO:00610241120.157
negative regulation of response to stimulusGO:00485852580.129
single organism behaviorGO:00447083910.120
regulation of organelle organizationGO:00330431960.114
regulation of cellular component sizeGO:0032535980.114
organelle fusionGO:0048284460.112
cell motilityGO:00488702510.111
actin filament based processGO:00300292200.102
single organism membrane organizationGO:0044802930.096
endocytosisGO:00068973100.094
Mouse
regulation of intracellular signal transductionGO:19025312360.090
regulation of localizationGO:00328792750.088
intracellular signal transductionGO:00355563000.084
ion transportGO:00068111450.084
cell adhesionGO:00071551360.084
multi organism behaviorGO:00517051750.080
regulation of cell projection organizationGO:0031344920.078
sensory perception of mechanical stimulusGO:0050954720.078
negative regulation of signal transductionGO:00099682060.077
cell migrationGO:00164772380.076
regulation of anatomical structure sizeGO:00900661630.076
negative regulation of cell communicationGO:00106482230.075
regulation of nervous system developmentGO:00519602480.074
immune response regulating signaling pathwayGO:000276420.069
Mouse
purine ribonucleoside monophosphate metabolic processGO:0009167500.068
positive regulation of cellular component organizationGO:00511301560.068
organelle fissionGO:00482853400.068
anion transmembrane transportGO:0098656260.067
cellular macromolecular complex assemblyGO:00346221530.066
cation transmembrane transportGO:0098655880.066
synaptic transmissionGO:00072682880.063
regulation of phosphate metabolic processGO:00192202100.062
regulation of anatomical structure morphogenesisGO:00226032420.060
response to other organismGO:00517072930.059
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.058
neural precursor cell proliferationGO:0061351750.057
regulation of neurogenesisGO:00507671580.057
regulation of multicellular organismal developmentGO:20000264140.057
negative regulation of cellular metabolic processGO:00313243820.057
immune system processGO:00023763470.055
Mouse
negative regulation of cellular component organizationGO:00511291080.054
regulation of phosphorylationGO:00423251470.052
cellular macromolecule localizationGO:00707272200.052
cation transportGO:00068121100.051
regulation of cellular component biogenesisGO:00440872010.051
signal transduction by phosphorylationGO:00230141070.051
actin cytoskeleton organizationGO:00300362060.051
regulation of growthGO:00400082330.051
regulation of cell developmentGO:00602842150.050
pigmentationGO:0043473750.050
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.049
Human
regulation of cell shapeGO:00083601130.047
response to radiationGO:00093141550.046
anion transportGO:0006820410.045
developmental growthGO:00485892800.045
adult behaviorGO:00305341370.044
cell junction organizationGO:0034330570.044
ameboidal type cell migrationGO:00016671510.043
response to biotic stimulusGO:00096072940.043
Mouse
imaginal disc derived appendage developmentGO:00487373990.043
localization of cellGO:00516742570.043
negative regulation of gene expressionGO:00106293870.042
cellular catabolic processGO:00442483720.042
response to light stimulusGO:00094161240.041
defense responseGO:00069523000.041
Mouse
response to bacteriumGO:00096171980.040
Mouse
appendage developmentGO:00487364010.039
carboxylic acid metabolic processGO:0019752920.039
single organism biosynthetic processGO:00447112060.039
amine metabolic processGO:0009308120.039
regulation of developmental growthGO:00486381740.039
positive regulation of growthGO:0045927750.039
nucleotide metabolic processGO:00091171610.039
regulation of transportGO:00510491810.039
intracellular transportGO:00469072280.038
oxoacid metabolic processGO:00434361030.038
adult locomotory behaviorGO:0008344760.037
cellular ketone metabolic processGO:0042180240.037
negative regulation of phosphate metabolic processGO:0045936450.036
response to external biotic stimulusGO:00432072930.035
Mouse
protein localizationGO:00081042840.034
response to endogenous stimulusGO:00097191190.034
protein modification processGO:00362114380.033
Human Mouse
nuclear divisionGO:00002803320.033
cellular response to organic substanceGO:00713101320.033
Human
cell cell junction organizationGO:0045216550.032
phosphorylationGO:00163102940.032
actin filament organizationGO:00070151260.032
taxisGO:00423303040.032
purine ribonucleotide metabolic processGO:00091501450.032
macromolecular complex assemblyGO:00650032560.032
negative regulation of organelle organizationGO:0010639560.031
positive regulation of biosynthetic processGO:00098913160.031
heterocycle catabolic processGO:00467001660.031
nucleoside phosphate metabolic processGO:00067531620.030
single organism intracellular transportGO:19025822070.030
renal tubule morphogenesisGO:0061333440.030
cellular nitrogen compound catabolic processGO:00442701650.030
enzyme linked receptor protein signaling pathwayGO:00071671790.029
Human
negative regulation of phosphorylationGO:0042326350.029
negative regulation of nervous system developmentGO:0051961920.029
establishment of localization in cellGO:00516494020.029
atp metabolic processGO:0046034490.028
cellular response to endogenous stimulusGO:0071495800.028
response to organic substanceGO:00100332840.028
Human Mouse
negative regulation of cellular biosynthetic processGO:00313272770.028
regulation of cell morphogenesisGO:00226041630.028
post embryonic appendage morphogenesisGO:00351203850.027
embryonic development via the syncytial blastodermGO:00017001480.027
regulation of response to stressGO:00801342000.027
single organism catabolic processGO:00447122280.027
catabolic processGO:00090564090.027
tissue migrationGO:00901301550.026
organelle assemblyGO:00709251980.026
developmental cell growthGO:0048588520.026
positive regulation of developmental processGO:00510941430.026
lipid localizationGO:0010876540.025
regulation of molecular functionGO:00650092170.025
regulation of cellular ketone metabolic processGO:001056530.025
store operated calcium entryGO:000211530.025
mapk cascadeGO:00001651070.025
axon developmentGO:00615642970.025
positive regulation of lipid biosynthetic processGO:004688930.024
growthGO:00400073590.024
regulation of cytoskeleton organizationGO:0051493890.024
body morphogenesisGO:001017120.024
negative regulation of cytoskeleton organizationGO:0051494300.024
regulation of response to external stimulusGO:00321011150.024
phagocytosisGO:00069092150.024
organic substance transportGO:00717022570.024
positive regulation of developmental growthGO:0048639620.024
glycosyl compound metabolic processGO:19016571270.024
cardiovascular system developmentGO:0072358820.023
axon guidanceGO:00074112330.023
aromatic compound catabolic processGO:00194391660.023
small molecule metabolic processGO:00442813050.023
nucleoside triphosphate metabolic processGO:00091411200.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
vesicle mediated transportGO:00161923810.022
Mouse
purine ribonucleoside metabolic processGO:00461281270.022
cellular response to radiationGO:0071478520.022
heart developmentGO:0007507820.022
agingGO:00075681430.022
Worm
transforming growth factor beta receptor signaling pathwayGO:0007179160.022
small gtpase mediated signal transductionGO:0007264880.022
cellular protein complex assemblyGO:0043623710.022
organic acid metabolic processGO:00060821030.022
establishment of protein localizationGO:00451841630.022
metal ion transportGO:0030001740.022
purine nucleoside monophosphate catabolic processGO:0009128380.021
nucleobase containing small molecule metabolic processGO:00550861740.021
very long chain fatty acid catabolic processGO:004276020.021
purine containing compound metabolic processGO:00725211550.021
regulation of immune responseGO:00507761180.021
Mouse
lipid metabolic processGO:00066291210.020
salivary gland developmentGO:00074311620.020
divalent metal ion transportGO:0070838260.020
positive regulation of nitrogen compound metabolic processGO:00511733540.020
regulation of immune system processGO:00026821760.020
Mouse
cellular response to peptide hormone stimulusGO:0071375280.020
purine nucleoside triphosphate metabolic processGO:00091441190.019
cellular response to nitrogen compoundGO:1901699510.019
regionalizationGO:00030024160.019
purine nucleoside monophosphate metabolic processGO:0009126500.019
regulation of ras protein signal transductionGO:0046578930.019
androgen metabolic processGO:000820910.019
compound eye developmentGO:00487493070.019
positive regulation of macromolecule metabolic processGO:00106044050.019
negative regulation of molecular functionGO:0044092510.018
negative regulation of phosphatase activityGO:001092330.018
regulation of cell differentiationGO:00455953020.018
purine nucleotide metabolic processGO:00061631460.018
regulation of cellular amine metabolic processGO:003323830.018
asymmetric stem cell divisionGO:0098722490.017
imaginal disc derived appendage morphogenesisGO:00351143950.017
regulation of phosphorus metabolic processGO:00511742100.017
epithelial cell differentiationGO:00308553220.017
protein complex assemblyGO:00064612000.017
monovalent inorganic cation transportGO:0015672400.017
atp catabolic processGO:0006200380.017
locomotory behaviorGO:00076261760.017
negative regulation of phosphorus metabolic processGO:0010563450.017
positive regulation of intracellular signal transductionGO:19025331160.017
plasma membrane organizationGO:0007009260.017
response to abiotic stimulusGO:00096283410.017
regulation of neuron differentiationGO:00456641030.017
appendage morphogenesisGO:00351073970.017
regulation of multi organism processGO:00439001310.017
heart morphogenesisGO:0003007320.017
positive regulation of lipid metabolic processGO:004583440.017
cellular amine metabolic processGO:0044106120.017
ras protein signal transductionGO:0007265880.017
positive regulation of cell communicationGO:00106472500.017
ovarian follicle cell developmentGO:00307072480.016
open tracheal system developmentGO:00074242040.016
regulation of mapk cascadeGO:0043408920.016
wing disc morphogenesisGO:00074723440.016
positive regulation of cellular component biogenesisGO:0044089800.016
regulation of cellular localizationGO:00603411360.016
homeostatic processGO:00425921990.016
regulation of cell cycle processGO:00105641810.016
purine containing compound catabolic processGO:00725231120.016
chromosome organizationGO:00512763600.016
nucleoside catabolic processGO:00091641120.016
rac protein signal transductionGO:001660130.016
chemotaxisGO:00069352490.016
peptidyl amino acid modificationGO:00181931050.016
Human
organophosphate metabolic processGO:00196371950.016
endomembrane system organizationGO:00102561190.016
chloride transportGO:0006821100.015
organic substance catabolic processGO:19015753080.015
positive regulation of signal transductionGO:00099672230.015
ribose phosphate metabolic processGO:00196931450.015
nucleotide catabolic processGO:00091661090.015
positive regulation of molecular functionGO:00440931360.015
developmental growth involved in morphogenesisGO:0060560650.015
negative regulation of signalingGO:00230572190.015
positive regulation of response to stimulusGO:00485843230.015
Mouse
eye developmentGO:00016543230.015
cellular protein localizationGO:00346131600.015
regulation of phosphatase activityGO:001092130.015
regulation of actin filament based processGO:0032970420.014
neuronal stem cell divisionGO:0036445350.014
biological adhesionGO:00226101380.014
regulation of immune effector processGO:0002697520.014
ribonucleotide metabolic processGO:00092591450.014
purine nucleoside metabolic processGO:00422781270.014
imaginal disc derived wing morphogenesisGO:00074763370.014
regulation of cellular catabolic processGO:00313291570.014
response to nitrogen compoundGO:1901698900.014
response to oxygen containing compoundGO:19017002000.014
Mouse
regulation of hemocyte proliferationGO:0035206370.014
cell divisionGO:00513012480.014
negative regulation of intracellular signal transductionGO:1902532570.014
inorganic ion transmembrane transportGO:0098660730.014
carbohydrate derivative metabolic processGO:19011352170.014
positive regulation of transportGO:0051050920.013
regulation of protein transportGO:0051223570.013
positive regulation of phosphorus metabolic processGO:00105621390.013
dna metabolic processGO:00062592270.013
spindle organizationGO:00070512530.013
positive regulation of phosphate metabolic processGO:00459371390.013
stress activated protein kinase signaling cascadeGO:0031098550.013
cellular protein modification processGO:00064644380.013
Human Mouse
regulation of actin cytoskeleton organizationGO:0032956420.013
regulation of cellular protein metabolic processGO:00322682430.013
fatty acid catabolic processGO:000906290.013
positive regulation of catalytic activityGO:00430851180.013
cell agingGO:000756920.013
negative regulation of protein metabolic processGO:0051248850.013
organic acid catabolic processGO:0016054160.012
neuron projection guidanceGO:00974852410.012
cellular response to hormone stimulusGO:0032870440.012
purine ribonucleoside monophosphate catabolic processGO:0009169380.012
muscle cell differentiationGO:00426921030.012
sensory perceptionGO:00076001960.012
embryonic morphogenesisGO:00485982060.012
Zebrafish
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of cell sizeGO:0008361630.012
negative regulation of nitrogen compound metabolic processGO:00511722650.012
regulation of catalytic activityGO:00507901850.012
septate junction assemblyGO:0019991260.012
regulation of protein modification processGO:00313991120.012
cell growthGO:00160491080.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
nucleoside triphosphate catabolic processGO:00091431080.012
organonitrogen compound catabolic processGO:19015651280.012
organic cyclic compound catabolic processGO:19013611680.012
small molecule catabolic processGO:0044282210.012
cuticle developmentGO:0042335860.012
positive regulation of signalingGO:00230562430.012
negative regulation of multicellular organismal processGO:00512411420.012
negative regulation of cell deathGO:0060548810.012
stress activated mapk cascadeGO:0051403520.012
regulation of synapse assemblyGO:0051963940.012
muscle structure developmentGO:00610612240.012
cellular response to abiotic stimulusGO:0071214580.011
organonitrogen compound metabolic processGO:19015643180.011
gland developmentGO:00487321910.011
gliogenesisGO:0042063800.011
dendrite developmentGO:00163582040.011
establishment or maintenance of cell polarityGO:00071631670.011
collateral sproutingGO:004866830.011
response to growth factorGO:0070848310.011
Human
regulation of adult chitin containing cuticle pigmentationGO:0048082130.011
purine nucleoside catabolic processGO:00061521120.011
transcription from rna polymerase ii promoterGO:00063663680.011
regulation of hydrolase activityGO:0051336970.011
regulation of synapse organizationGO:00508071100.011
negative regulation of cell differentiationGO:00455961430.011
internal peptidyl lysine acetylationGO:0018393380.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
regulation of protein polymerizationGO:0032271280.011
negative regulation of cellular protein metabolic processGO:0032269850.011
nucleocytoplasmic transportGO:0006913720.011
developmental pigmentationGO:0048066680.011
nucleoside monophosphate metabolic processGO:0009123520.011
nucleoside metabolic processGO:00091161270.011
regulation of synapse structure and activityGO:00508031280.010
deathGO:00162652840.010
monocarboxylic acid catabolic processGO:0072329100.010
protein phosphorylationGO:00064681690.010
Human Mouse
egg activationGO:000734390.010
organophosphate catabolic processGO:00464341120.010
regulation of response to biotic stimulusGO:0002831630.010
defense response to other organismGO:00985422250.010
ribonucleoside catabolic processGO:00424541120.010

MAPk-Ak2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.013
musculoskeletal system diseaseDOID:1700.010