Drosophila melanogaster

16 known processes

Spn3 (Dmel_CG9334)

Serine protease inhibitor 3

(Aliases: Dmel\CG9334,Sp3,Spn38F,CG9334,sp3)

Spn3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sterol homeostasisGO:005509240.187
cholesterol homeostasisGO:004263230.143
inseminationGO:0007320220.121
sperm competitionGO:0046692210.059
protein modification processGO:00362114380.052
small molecule metabolic processGO:00442813050.048
organic acid metabolic processGO:00060821030.043
carboxylic acid metabolic processGO:0019752920.043
sperm storageGO:0046693100.042
vesicle mediated transportGO:00161923810.040
homeostatic processGO:00425921990.038
oxoacid metabolic processGO:00434361030.037
imaginal disc derived appendage developmentGO:00487373990.037
catabolic processGO:00090564090.035
response to abiotic stimulusGO:00096283410.035
cellular protein modification processGO:00064644380.034
imaginal disc derived wing morphogenesisGO:00074763370.033
multicellular organismal reproductive behaviorGO:00330571100.033
endocytosisGO:00068973100.033
appendage morphogenesisGO:00351073970.033
cell cell signaling involved in cell fate commitmentGO:00451682100.031
multi organism behaviorGO:00517051750.031
appendage developmentGO:00487364010.031
organonitrogen compound metabolic processGO:19015643180.031
Fly
phagocytosisGO:00069092150.030
imaginal disc derived appendage morphogenesisGO:00351143950.030
cellular catabolic processGO:00442483720.029
regulation of multicellular organismal developmentGO:20000264140.029
wing disc morphogenesisGO:00074723440.029
organic hydroxy compound metabolic processGO:1901615830.029
post embryonic appendage morphogenesisGO:00351203850.029
negative regulation of cellular metabolic processGO:00313243820.028
Rat Fly
body morphogenesisGO:001017120.028
regionalizationGO:00030024160.027
developmental growthGO:00485892800.027
Rat
matingGO:00076181200.026
positive regulation of response to stimulusGO:00485843230.026
response to external biotic stimulusGO:00432072930.026
organic substance catabolic processGO:19015753080.026
ethanolamine containing compound metabolic processGO:004243940.026
lateral inhibitionGO:00463312060.025
positive regulation of cell communicationGO:00106472500.025
lipid metabolic processGO:00066291210.025
female mating behaviorGO:0060180300.025
cellular amino acid metabolic processGO:0006520610.024
oxidation reduction processGO:00551141230.024
single organism behaviorGO:00447083910.024
regulation of localizationGO:00328792750.024
triglyceride biosynthetic processGO:001943220.023
forebrain developmentGO:003090020.023
open tracheal system developmentGO:00074242040.023
response to other organismGO:00517072930.023
compound eye developmentGO:00487493070.023
establishment of localization in cellGO:00516494020.023
negative regulation of gene expressionGO:00106293870.023
Rat Fly
cell proliferationGO:00082832990.023
acylglycerol catabolic processGO:004646430.023
response to biotic stimulusGO:00096072940.023
regulation of female receptivityGO:0045924240.023
kidney developmentGO:000182230.022
compound eye morphogenesisGO:00017452490.022
growthGO:00400073590.022
Rat
single organism catabolic processGO:00447122280.022
organic substance transportGO:00717022570.022
phosphorylationGO:00163102940.022
chromosome organizationGO:00512763600.022
regulation of female receptivity post matingGO:0046008170.022
immune system processGO:00023763470.022
Fly
lipid homeostasisGO:0055088330.022
cellular lipid metabolic processGO:0044255830.021
regulation of cellular ketone metabolic processGO:001056530.021
nuclear divisionGO:00002803320.021
single organism biosynthetic processGO:00447112060.021
neurological system processGO:00508773580.021
positive regulation of lipid storageGO:001088440.021
defense response to other organismGO:00985422250.021
intracellular signal transductionGO:00355563000.021
epithelial cell differentiationGO:00308553220.021
amine metabolic processGO:0009308120.020
salivary gland developmentGO:00074311620.020
protein complex biogenesisGO:00702712010.020
negative regulation of female receptivityGO:0007621140.020
response to nutrient levelsGO:00316671140.020
Rat
positive regulation of signal transductionGO:00099672230.020
response to organic substanceGO:00100332840.020
organelle fissionGO:00482853400.020
positive regulation of signalingGO:00230562430.020
regulation of immune system processGO:00026821760.020
Fly
response to lipopolysaccharideGO:003249640.020
cellular amine metabolic processGO:0044106120.019
negative regulation of signalingGO:00230572190.019
Fly
protein localizationGO:00081042840.019
regulation of response to stressGO:00801342000.019
Rat
cellular response to dna damage stimulusGO:00069742230.019
sensory perception of smellGO:0007608800.019
defense response to bacteriumGO:00427421780.019
regulation of cellular amine metabolic processGO:003323830.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
regulation of molecular functionGO:00650092170.019
Rat Fly
cholesterol transportGO:003030120.019
negative regulation of signal transductionGO:00099682060.018
Fly
immune responseGO:00069552460.018
Fly
macromolecular complex assemblyGO:00650032560.018
negative regulation of response to stimulusGO:00485852580.018
Rat Fly
carbohydrate derivative metabolic processGO:19011352170.018
proteolysisGO:00065081920.018
Rat Fly
negative regulation of cell communicationGO:00106482230.018
Fly
regulation of cell differentiationGO:00455953020.018
cell divisionGO:00513012480.018
xenobiotic catabolic processGO:004217810.018
regulation of cellular protein metabolic processGO:00322682430.018
Rat Fly
steroid catabolic processGO:000670610.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
Fly
reproductive behaviorGO:00190981220.018
camera type eye developmentGO:004301040.018
photoreceptor cell differentiationGO:00465301700.018
gland developmentGO:00487321910.018
telencephalon developmentGO:002153720.017
negative regulation of developmental processGO:00510932010.017
positive regulation of biosynthetic processGO:00098913160.017
cell deathGO:00082192790.017
adult behaviorGO:00305341370.017
positive regulation of macromolecule metabolic processGO:00106044050.017
triglyceride catabolic processGO:001943330.017
single organism intracellular transportGO:19025822070.017
sensory organ morphogenesisGO:00905962600.017
regulation of multi organism processGO:00439001310.017
Fly
regulation of transportGO:00510491810.017
regulation of cellular amino acid metabolic processGO:000652100.017
intracellular transportGO:00469072280.017
eye morphogenesisGO:00485922600.017
developmental maturationGO:00217001720.017
antimicrobial humoral responseGO:0019730990.016
Fly
positive regulation of cellular biosynthetic processGO:00313283160.016
small gtpase mediated signal transductionGO:0007264880.016
cellular response to chemical stimulusGO:00708871990.016
mating behaviorGO:00076171060.016
organophosphate metabolic processGO:00196371950.016
cellular ketone metabolic processGO:0042180240.016
response to bacteriumGO:00096171980.016
defense responseGO:00069523000.016
acylglycerol biosynthetic processGO:004646320.016
tube morphogenesisGO:00352391910.016
positive regulation of sequestering of triglycerideGO:001089010.016
regulation of protein metabolic processGO:00512462560.016
Rat Fly
regulation of cell cycleGO:00517262910.016
tube developmentGO:00352952440.016
positive regulation of cell motilityGO:200014730.016
response to extracellular stimulusGO:00099911160.016
Rat
chemical homeostasisGO:0048878920.016
axis specificationGO:00097981670.015
eye developmentGO:00016543230.015
regulation of nervous system developmentGO:00519602480.015
eye photoreceptor cell differentiationGO:00017541450.015
peptide metabolic processGO:0006518800.015
Fly
deathGO:00162652840.015
dna metabolic processGO:00062592270.015
segmentationGO:00352822070.015
protein hydroxylationGO:001812610.015
organic cyclic compound catabolic processGO:19013611680.015
anion homeostasisGO:005508130.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
cellular macromolecule catabolic processGO:00442651360.015
macromolecule catabolic processGO:00090571610.015
negative regulation of multicellular organismal processGO:00512411420.015
response to monosaccharideGO:003428440.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
multi multicellular organism processGO:00447061230.015
regulation of catalytic activityGO:00507901850.015
Rat Fly
taxisGO:00423303040.015
regulation of cell developmentGO:00602842150.015
copulationGO:0007620260.015
protein complex assemblyGO:00064612000.015
gland morphogenesisGO:00226121450.015
gene silencingGO:00164581380.015
spermatogenesisGO:00072832000.015
response to copper ionGO:004668840.015
male gamete generationGO:00482322010.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
ras protein signal transductionGO:0007265880.015
respiratory system developmentGO:00605412130.015
response to radiationGO:00093141550.014
cellular nitrogen compound catabolic processGO:00442701650.014
morphogenesis of an epitheliumGO:00020092760.014
response to organophosphorusGO:004668320.014
epithelial cell developmentGO:00020642740.014
embryonic pattern specificationGO:00098801740.014
negative regulation of biosynthetic processGO:00098902770.014
regulation of gene expression epigeneticGO:00400291280.014
regulation of phosphorus metabolic processGO:00511742100.014
negative regulation of cellular biosynthetic processGO:00313272770.014
negative regulation of rna biosynthetic processGO:19026792400.014
blastoderm segmentationGO:00073501590.014
cellular macromolecule localizationGO:00707272200.014
carbohydrate derivative biosynthetic processGO:1901137850.014
regulation of anatomical structure morphogenesisGO:00226032420.014
multicellular organismal agingGO:00102591400.014
meiotic cell cycleGO:00513211710.014
aromatic compound catabolic processGO:00194391660.014
response to oxygen containing compoundGO:19017002000.014
protein phosphorylationGO:00064681690.014
organelle assemblyGO:00709251980.014
sensory perception of chemical stimulusGO:00076061160.014
mitotic nuclear divisionGO:00070672130.014
response to hexoseGO:000974630.014
regulation of anatomical structure sizeGO:00900661630.014
positive regulation of multicellular organismal processGO:00512401430.014
multi organism reproductive behaviorGO:00447051210.014
regulation of developmental growthGO:00486381740.014
tissue morphogenesisGO:00487292970.014
salivary gland morphogenesisGO:00074351450.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
protein maturationGO:0051604710.014
Fly
exocrine system developmentGO:00352721620.014
regulation of cellular component biogenesisGO:00440872010.014
regulation of intracellular signal transductionGO:19025312360.014
positive regulation of gene expressionGO:00106282900.013
axon developmentGO:00615642970.013
glycerolipid catabolic processGO:004650330.013
immune effector processGO:0002252980.013
Fly
heterocycle catabolic processGO:00467001660.013
positive regulation of rna metabolic processGO:00512542710.013
compound eye photoreceptor cell differentiationGO:00017511400.013
positive regulation of rna biosynthetic processGO:19026802660.013
regulation of phosphate metabolic processGO:00192202100.013
positive regulation of cell migrationGO:003033520.013
peptidyl amino acid modificationGO:00181931050.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
regulation of defense responseGO:00313471020.013
Rat
enzyme linked receptor protein signaling pathwayGO:00071671790.013
transcription from rna polymerase ii promoterGO:00063663680.013
peptidyl proline modificationGO:001820830.013
synaptic transmissionGO:00072682880.013
connective tissue developmentGO:006144830.013
single organism cellular localizationGO:19025801800.013
negative regulation of female receptivity post matingGO:0045434120.013
sulfur compound metabolic processGO:0006790590.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
regulation of immune responseGO:00507761180.013
Fly
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
transmembrane transportGO:00550851390.013
protein transportGO:00150311550.013
response to woundingGO:0009611940.013
Rat
nucleobase containing compound catabolic processGO:00346551650.013
regulation of mitotic cell cycleGO:00073461900.013
rna localizationGO:00064031150.013
negative regulation of rna metabolic processGO:00512532510.013
regulation of growthGO:00400082330.013
cytoplasmic transportGO:00164821300.013
regulation of cellular localizationGO:00603411360.012
mapk cascadeGO:00001651070.012
maintenance of locationGO:0051235730.012
modification dependent macromolecule catabolic processGO:0043632790.012
negative regulation of cell differentiationGO:00455961430.012
programmed cell deathGO:00125012570.012
phosphatidic acid metabolic processGO:004647310.012
dorsal ventral pattern formationGO:00099531330.012
positive regulation of transcription dna templatedGO:00458932660.012
regulation of cell deathGO:00109411730.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
agingGO:00075681430.012
cellular macromolecular complex assemblyGO:00346221530.012
chaeta developmentGO:0022416970.012
response to glucoseGO:000974920.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
very long chain fatty acid metabolic processGO:000003840.012
neutral lipid biosynthetic processGO:004646020.012
organophosphate catabolic processGO:00464341120.012
rna processingGO:00063961470.012
immune response activating signal transductionGO:000275720.012
cell cycle phase transitionGO:00447701400.012
alditol phosphate metabolic processGO:005264620.012
g protein coupled receptor signaling pathwayGO:00071861360.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
embryonic development via the syncytial blastodermGO:00017001480.012
ovarian follicle cell developmentGO:00307072480.012
establishment of protein localizationGO:00451841630.012
endomembrane system organizationGO:00102561190.012
dorsal ventral axis specificationGO:0009950660.012
response to organic cyclic compoundGO:0014070890.012
positive regulation of cellular amine metabolic processGO:003324000.012
axonogenesisGO:00074092900.012
monocarboxylic acid metabolic processGO:0032787290.012
phosphatidylcholine metabolic processGO:004647030.012
positive regulation of phosphorus metabolic processGO:00105621390.012
nucleoside phosphate metabolic processGO:00067531620.012
cell adhesionGO:00071551360.012
Rat
chromatin remodelingGO:0006338720.012
limb developmentGO:006017310.012
response to endogenous stimulusGO:00097191190.012
dendrite morphogenesisGO:00488131990.011
chromatin modificationGO:00165681470.011
regulation of phosphorylationGO:00423251470.011
innate immune responseGO:00450871440.011
chromatin organizationGO:00063252070.011
wnt signaling pathwayGO:0016055980.011
spindle organizationGO:00070512530.011
regulation of sterol transportGO:003237110.011
regulation of catabolic processGO:00098941700.011
regulation of cellular catabolic processGO:00313291570.011
regulation of synapse structure and activityGO:00508031280.011
regulation of reproductive processGO:2000241540.011
protein catabolic processGO:00301631010.011
cell migrationGO:00164772380.011
actin cytoskeleton organizationGO:00300362060.011
polyol biosynthetic processGO:004617330.011
medium chain fatty acid metabolic processGO:005179110.011
regulation of humoral immune responseGO:0002920510.011
Fly
cellular response to organic substanceGO:00713101320.011
regulation of sequestering of triglycerideGO:001088930.011
vitamin biosynthetic processGO:000911010.011
immune response regulating signaling pathwayGO:000276420.011
regulation of production of molecular mediator of immune responseGO:0002700440.011
Fly
mesenchymal cell differentiationGO:004876210.011
mitotic spindle organizationGO:00070522200.011
regulation of epithelial cell differentiationGO:003085640.011
sensory perceptionGO:00076001960.011
regulation of organelle organizationGO:00330431960.011
modification dependent protein catabolic processGO:0019941780.011
fat soluble vitamin metabolic processGO:000677510.011
cell maturationGO:00484691440.011
retina development in camera type eyeGO:006004140.011
nucleobase containing small molecule metabolic processGO:00550861740.011
response to temperature stimulusGO:00092661060.011
central nervous system developmentGO:00074172010.011
notch signaling pathwayGO:00072191200.011
axon guidanceGO:00074112330.011
cell motilityGO:00488702510.011
hindbrain developmentGO:003090220.011
regulation of programmed cell deathGO:00430671520.011
cellular protein localizationGO:00346131600.011
embryonic morphogenesisGO:00485982060.011
positive regulation of intracellular signal transductionGO:19025331160.011
photoreceptor cell developmentGO:0042461960.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
negative regulation of protein metabolic processGO:0051248850.011
Rat Fly
neutral lipid catabolic processGO:004646130.011
dendrite developmentGO:00163582040.011
chromosome segregationGO:00070591570.011
response to starvationGO:0042594970.011
androgen metabolic processGO:000820910.011
localization of cellGO:00516742570.011
regulation of cellular response to stressGO:0080135890.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
hematopoietic progenitor cell differentiationGO:000224410.011
somatic muscle developmentGO:0007525660.011
estrogen metabolic processGO:000821010.011
kidney epithelium developmentGO:007207330.011
cellular response to ethanolGO:007136140.011
centrosome organizationGO:00512971630.011
microtubule organizing center organizationGO:00310231680.011
mesenchymal cell developmentGO:001403110.010
regulation of proteolysisGO:0030162870.010
Rat Fly
cellular amide metabolic processGO:0043603800.010
Fly
anterior posterior pattern specificationGO:00099521360.010
positive regulation of phosphate metabolic processGO:00459371390.010
positive regulation of developmental processGO:00510941430.010
embryonic axis specificationGO:00005781070.010
nucleotide metabolic processGO:00091171610.010
cognitionGO:00508901410.010
mrna metabolic processGO:00160711240.010
cellular protein catabolic processGO:0044257830.010
regulation of lipid transportGO:003236830.010
regulation of epithelial cell proliferationGO:005067840.010
locomotory behaviorGO:00076261760.010
defense response to gram negative bacteriumGO:0050829940.010
nitrogen compound transportGO:0071705850.010
response to organonitrogen compoundGO:0010243750.010
organonitrogen compound biosynthetic processGO:19015661170.010
vitamin metabolic processGO:000676620.010
monocarboxylic acid transportGO:001571830.010
cellular component assembly involved in morphogenesisGO:00109271510.010
positive regulation of catabolic processGO:00098961050.010
regulation of cell cycle phase transitionGO:19019871300.010
determination of adult lifespanGO:00083401370.010
synapse organizationGO:00508081960.010
actin filament based processGO:00300292200.010
regulation of notch signaling pathwayGO:00085931000.010
positive regulation of molecular functionGO:00440931360.010
tripartite regional subdivisionGO:00073511030.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010
ribonucleotide metabolic processGO:00092591450.010
limb morphogenesisGO:003510810.010
glycoprotein metabolic processGO:0009100410.010
ribonucleoside metabolic processGO:00091191270.010
mitotic sister chromatid segregationGO:0000070870.010

Spn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
diabetes mellitusDOID:935100.023
glucose metabolism diseaseDOID:419400.023
acquired metabolic diseaseDOID:006015800.023
carbohydrate metabolism diseaseDOID:005001300.023
disease of metabolismDOID:001466700.023
inherited metabolic disorderDOID:65500.023
nervous system diseaseDOID:86300.019
type 2 diabetes mellitusDOID:935200.017
familial hypertriglyceridemiaDOID:005052700.015
lipid metabolism disorderDOID:314600.015
sensory system diseaseDOID:005015500.012
cardiovascular system diseaseDOID:128700.012
artery diseaseDOID:005082800.012
hypertensionDOID:1076300.012
vascular diseaseDOID:17800.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
eye and adnexa diseaseDOID:149200.010