IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

RpL18 (Dmel_CG8615)

Ribosomal protein L18

(Aliases: CG8615,M(3)65F,Dmel\CG8615,RpL18e)

Entrez: 38794
FLYBASE: FBgn0035753
UniProtKB: Q9VS34
UniProtKB: M9PHM6

Process Predictions
Disease Predictions

RpL18 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.932
spindle elongation	GO:0051231	83	0.674
centrosome cycle	GO:0007098	137	0.589
spindle organization	GO:0007051	253	0.552
cytoplasmic translation	GO:0002181	0	0.507
mitotic spindle organization	GO:0007052	220	0.503
centrosome organization	GO:0051297	163	0.441
microtubule organizing center organization	GO:0031023	168	0.389
translation	GO:0006412	69	0.367
centrosome duplication	GO:0051298	121	0.342
larval development	GO:0002164	104	0.277	Worm
ribosomal large subunit biogenesis	GO:0042273	1	0.226
rrna processing	GO:0006364	3	0.175
death	GO:0016265	284	0.108	Worm
negative regulation of gene expression	GO:0010629	387	0.103
endocytosis	GO:0006897	310	0.100	Worm
programmed cell death	GO:0012501	257	0.098	Worm
regulation of protein metabolic process	GO:0051246	256	0.082
immune system process	GO:0002376	347	0.081
cellular catabolic process	GO:0044248	372	0.077
embryo development ending in birth or egg hatching	GO:0009792	152	0.062	Worm
body morphogenesis	GO:0010171	2	0.057
ribonucleoprotein complex biogenesis	GO:0022613	31	0.056
regulation of cellular protein metabolic process	GO:0032268	243	0.055
phagocytosis	GO:0006909	215	0.047
regulation of translation	GO:0006417	56	0.045
catabolic process	GO:0009056	409	0.042
cellular response to chemical stimulus	GO:0070887	199	0.039
vesicle mediated transport	GO:0016192	381	0.039	Worm
cellular protein modification process	GO:0006464	438	0.038
rna processing	GO:0006396	147	0.038
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.037
organic acid metabolic process	GO:0006082	103	0.037
cell proliferation	GO:0008283	299	0.036
aromatic compound catabolic process	GO:0019439	166	0.035
molting cycle	GO:0042303	56	0.035	Worm
positive regulation of biosynthetic process	GO:0009891	316	0.034
small molecule metabolic process	GO:0044281	305	0.034
positive regulation of phosphate metabolic process	GO:0045937	139	0.034
organelle assembly	GO:0070925	198	0.034
negative regulation of biosynthetic process	GO:0009890	277	0.032
positive regulation of protein metabolic process	GO:0051247	128	0.032
posttranscriptional regulation of gene expression	GO:0010608	145	0.031
intracellular signal transduction	GO:0035556	300	0.031
positive regulation of cellular protein metabolic process	GO:0032270	118	0.030
cell death	GO:0008219	279	0.029	Worm
macromolecule catabolic process	GO:0009057	161	0.029
rna localization	GO:0006403	115	0.028
axon development	GO:0061564	297	0.027
developmental growth	GO:0048589	280	0.027
negative regulation of translation	GO:0017148	28	0.027
organic substance catabolic process	GO:1901575	308	0.027
single organism biosynthetic process	GO:0044711	206	0.026
response to external biotic stimulus	GO:0043207	293	0.026
cellular ketone metabolic process	GO:0042180	24	0.026
regulation of localization	GO:0032879	275	0.026
negative regulation of cellular metabolic process	GO:0031324	382	0.026
ncrna metabolic process	GO:0034660	43	0.025
organic cyclic compound catabolic process	GO:1901361	168	0.025
ribonucleoside catabolic process	GO:0042454	112	0.024
macromolecular complex assembly	GO:0065003	256	0.024
multicellular organismal aging	GO:0010259	140	0.023
cell recognition	GO:0008037	102	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.022
regulation of cell cycle	GO:0051726	291	0.022
response to oxygen containing compound	GO:1901700	200	0.022
establishment of localization in cell	GO:0051649	402	0.021
response to organic substance	GO:0010033	284	0.021
protein modification process	GO:0036211	438	0.021
cellular macromolecule catabolic process	GO:0044265	136	0.021
positive regulation of phosphorylation	GO:0042327	87	0.021
positive regulation of phosphorus metabolic process	GO:0010562	139	0.021
response to other organism	GO:0051707	293	0.021
intracellular transport	GO:0046907	228	0.021
protein phosphorylation	GO:0006468	169	0.021
heterocycle catabolic process	GO:0046700	166	0.020
nucleocytoplasmic transport	GO:0006913	72	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
cytoplasmic transport	GO:0016482	130	0.020
regulation of phosphate metabolic process	GO:0019220	210	0.020
growth	GO:0040007	359	0.019
positive regulation of catalytic activity	GO:0043085	118	0.019
phosphorylation	GO:0016310	294	0.018
cellular response to organic substance	GO:0071310	132	0.018
aging	GO:0007568	143	0.018
response to hexose	GO:0009746	3	0.018
apoptotic process	GO:0006915	159	0.018	Worm
single organism catabolic process	GO:0044712	228	0.018
organic substance transport	GO:0071702	257	0.018
cellular nitrogen compound catabolic process	GO:0044270	165	0.018
positive regulation of molecular function	GO:0044093	136	0.017
regulation of intracellular signal transduction	GO:1902531	236	0.017
small gtpase mediated signal transduction	GO:0007264	88	0.017
regulation of molecular function	GO:0065009	217	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
determination of adult lifespan	GO:0008340	137	0.016
tissue morphogenesis	GO:0048729	297	0.016
amine metabolic process	GO:0009308	12	0.016
oxoacid metabolic process	GO:0043436	103	0.016
positive regulation of cell communication	GO:0010647	250	0.015
innate immune response	GO:0045087	144	0.015
cell migration	GO:0016477	238	0.015
compound eye development	GO:0048749	307	0.015
regulation of phosphatase activity	GO:0010921	3	0.015
negative regulation of signal transduction	GO:0009968	206	0.015
nuclear transport	GO:0051169	72	0.015
negative regulation of cell communication	GO:0010648	223	0.015
inorganic ion transmembrane transport	GO:0098660	73	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
ribonucleoprotein complex subunit organization	GO:0071826	28	0.014
response to biotic stimulus	GO:0009607	294	0.014
membrane organization	GO:0061024	112	0.014
mitotic dna integrity checkpoint	GO:0044774	75	0.014
central nervous system development	GO:0007417	201	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
nucleobase containing compound catabolic process	GO:0034655	165	0.013
morphogenesis of follicular epithelium	GO:0016333	36	0.013
positive regulation of peptidase activity	GO:0010952	29	0.013
axon guidance	GO:0007411	233	0.013
defense response	GO:0006952	300	0.013
regulation of catalytic activity	GO:0050790	185	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
positive regulation of translation	GO:0045727	12	0.013
sex differentiation	GO:0007548	81	0.013
proteolysis	GO:0006508	192	0.013
response to abiotic stimulus	GO:0009628	341	0.013
cell division	GO:0051301	248	0.013
salivary gland histolysis	GO:0035070	88	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.012
mitotic nuclear division	GO:0007067	213	0.012
neuron recognition	GO:0008038	101	0.012
multicellular organism growth	GO:0035264	46	0.012
positive regulation of intracellular signal transduction	GO:1902533	116	0.012
positive regulation of macromolecule metabolic process	GO:0010604	405	0.012
localization of cell	GO:0051674	257	0.012
cell motility	GO:0048870	251	0.012
single organism intracellular transport	GO:1902582	207	0.011
hematopoietic or lymphoid organ development	GO:0048534	57	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
nitrogen compound transport	GO:0071705	85	0.011
phosphatidic acid metabolic process	GO:0046473	1	0.011
homeostatic process	GO:0042592	199	0.011
meiotic cell cycle	GO:0051321	171	0.011
humoral immune response	GO:0006959	117	0.011
translational elongation	GO:0006414	4	0.010
lipid metabolic process	GO:0006629	121	0.010
carboxylic acid metabolic process	GO:0019752	92	0.010
histolysis	GO:0007559	102	0.010
positive regulation of multicellular organismal process	GO:0051240	143	0.010
notch signaling pathway	GO:0007219	120	0.010

RpL18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
hematopoietic system disease	DOID:74	0.038
immune system disease	DOID:2914	0.038
disease of anatomical entity	DOID:7	0.038
anemia	DOID:2355	0.038
aplastic anemia	DOID:12449	0.038
congenital hypoplastic anemia	DOID:1342	0.038
bone marrow disease	DOID:4961	0.038

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