Drosophila melanogaster

28 known processes

m4 (Dmel_CG6099)

E(spl) region transcript m4

(Aliases: CG6099,HLHm4,Dmel\CG6099,E(spl)m4)

m4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ precursor cell fate determinationGO:0016360191.000
Fly
cell fate determination involved in pattern specificationGO:0060582190.991
Fly
neuron fate determinationGO:004866410.990
cell fate determinationGO:0001709910.969
Fly
r7 cell differentiationGO:0045466430.897
formation of anatomical boundaryGO:0048859370.877
Fly
regionalizationGO:00030024160.865
Fly
notch signaling pathwayGO:00072191200.851
formation of organ boundaryGO:0010160300.829
Fly
cell fate specificationGO:0001708710.814
compound eye morphogenesisGO:00017452490.801
cell fate commitment involved in pattern specificationGO:0060581310.784
Fly
compound eye developmentGO:00487493070.781
regulation of timing of cell differentiationGO:004850510.756
r1 r6 cell differentiationGO:004805240.721
eye morphogenesisGO:00485922600.705
eye photoreceptor cell differentiationGO:00017541450.655
eye developmentGO:00016543230.650
sensory organ morphogenesisGO:00905962600.625
compound eye photoreceptor cell differentiationGO:00017511400.552
stem cell maintenanceGO:0019827670.534
hair cell differentiationGO:0035315470.533
organ formationGO:0048645390.512
Fly
glial cell fate commitmentGO:002178130.510
stem cell fate specificationGO:004886620.500
neuron fate specificationGO:0048665120.496
negative regulation of cell developmentGO:0010721620.476
neuroblast fate specificationGO:001401820.449
epithelial cell differentiationGO:00308553220.418
positive regulation of bmp signaling pathwayGO:003051350.411
cranial nerve developmentGO:002154510.390
sensory organ boundary specificationGO:0008052220.368
Fly
tissue morphogenesisGO:00487292970.368
Fly
regulation of notch signaling pathwayGO:00085931000.351
Fly
negative regulation of response to stimulusGO:00485852580.350
Fly
negative regulation of gene expressionGO:00106293870.348
nephron epithelium morphogenesisGO:007208830.317
regulation of nervous system developmentGO:00519602480.317
negative regulation of signalingGO:00230572190.308
Fly
tyrosine phosphorylation of stat proteinGO:000726010.304
somatic sex determinationGO:001899320.291
sex determination establishment of x a ratioGO:000754010.289
camera type eye developmentGO:004301040.288
axonogenesisGO:00074092900.282
axon ensheathment in central nervous systemGO:003229130.271
regulation of glial cell differentiationGO:004568510.256
regulation of stem cell proliferationGO:0072091400.246
regulation of cell morphogenesisGO:00226041630.234
appendage developmentGO:00487364010.233
negative regulation of neurogenesisGO:0050768530.221
regulation of cell developmentGO:00602842150.220
appendage morphogenesisGO:00351073970.220
epithelial cell developmentGO:00020642740.206
kidney epithelium developmentGO:007207330.202
peripheral nervous system neuron developmentGO:004893580.197
bolwig s organ developmentGO:005503480.195
regulation of neurogenesisGO:00507671580.190
chaeta developmentGO:0022416970.184
columnar cuboidal epithelial cell differentiationGO:00020652560.182
regulation of neuroblast proliferationGO:1902692340.179
stem cell fate determinationGO:0048867150.178
imaginal disc derived wing morphogenesisGO:00074763370.172
negative regulation of biosynthetic processGO:00098902770.169
regulation of response to stressGO:00801342000.166
regulation of hematopoietic progenitor cell differentiationGO:190153210.164
gliogenesisGO:0042063800.163
stem cell fate commitmentGO:0048865250.161
segment specificationGO:0007379330.160
establishment of tissue polarityGO:0007164870.154
Fly
negative regulation of cell communicationGO:00106482230.147
Fly
negative regulation of signal transductionGO:00099682060.146
Fly
stem cell differentiationGO:00488631170.143
intracellular signal transductionGO:00355563000.138
axon developmentGO:00615642970.136
positive regulation of notch signaling pathwayGO:0045747340.134
regulation of multicellular organismal developmentGO:20000264140.131
photoreceptor cell differentiationGO:00465301700.130
regulation of mitosisGO:0007088560.130
negative regulation of nucleic acid templated transcriptionGO:19035072400.127
morphogenesis of an epitheliumGO:00020092760.126
Fly
renal tubule morphogenesisGO:0061333440.126
primary sex determination somaGO:000753920.124
sex determinationGO:0007530180.122
negative regulation of macromolecule biosynthetic processGO:00105582700.122
regulation of transcription from rna polymerase ii promoterGO:00063573780.121
connective tissue developmentGO:006144830.118
nephron tubule formationGO:007207930.118
negative regulation of nitrogen compound metabolic processGO:00511722650.117
regulation of neural precursor cell proliferationGO:2000177350.116
positive regulation of signal transductionGO:00099672230.114
spinal cord patterningGO:002151110.114
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.113
chorion containing eggshell formationGO:00073041050.113
cellular amino acid metabolic processGO:0006520610.113
tube developmentGO:00352952440.110
epidermal growth factor receptor signaling pathwayGO:0007173580.109
telencephalon developmentGO:002153720.109
stem cell developmentGO:0048864790.104
epidermal cell differentiationGO:0009913510.102
chaeta morphogenesisGO:0008407420.102
eye photoreceptor cell fate commitmentGO:0042706370.102
defense responseGO:00069523000.101
regulation of cellular amino acid metabolic processGO:000652100.101
epithelial tube morphogenesisGO:0060562880.100
regulation of cellular amine metabolic processGO:003323830.100
negative regulation of notch signaling pathwayGO:0045746410.100
Fly
regulation of neuron differentiationGO:00456641030.099
gland morphogenesisGO:00226121450.099
glial cell differentiationGO:0010001350.099
biological adhesionGO:00226101380.094
cellular ketone metabolic processGO:0042180240.092
bolwig s organ morphogenesisGO:000174680.092
mitotic nuclear divisionGO:00070672130.091
brain developmentGO:00074201200.091
nerve developmentGO:002167560.090
regulation of cell morphogenesis involved in differentiationGO:0010769610.090
tube morphogenesisGO:00352391910.089
embryonic organ developmentGO:0048568500.089
positive regulation of cellular amine metabolic processGO:003324000.088
embryonic organ morphogenesisGO:004856250.086
negative regulation of multicellular organismal processGO:00512411420.086
regulation of tyrosine phosphorylation of stat proteinGO:004250910.085
neuroblast proliferationGO:0007405740.085
regulation of cellular ketone metabolic processGO:001056530.083
positive regulation of cellular amino acid metabolic processGO:004576400.083
forebrain developmentGO:003090020.081
neuronal action potentialGO:0019228100.080
spinal cord dorsal ventral patterningGO:002151310.079
dosage compensationGO:0007549160.079
regulation of epithelial cell differentiationGO:003085640.078
glial cell developmentGO:0021782270.077
neuron projection guidanceGO:00974852410.077
dorsal ventral pattern formationGO:00099531330.076
compound eye cone cell differentiationGO:0042675130.074
nuclear divisionGO:00002803320.074
larval behaviorGO:0030537420.072
actin cytoskeleton organizationGO:00300362060.071
positive regulation of nucleobase containing compound metabolic processGO:00459353320.070
nephron tubule developmentGO:007208030.070
negative regulation of transcription dna templatedGO:00458922370.070
neuroepithelial cell differentiationGO:006056360.070
compound eye photoreceptor fate commitmentGO:0001752360.070
immune system processGO:00023763470.069
dendrite morphogenesisGO:00488131990.068
regulation of neuron projection developmentGO:0010975690.068
positive regulation of macromolecule metabolic processGO:00106044050.067
regulation of cell differentiationGO:00455953020.065
positive regulation of response to stimulusGO:00485843230.065
nephron epithelium developmentGO:007200930.064
carboxylic acid metabolic processGO:0019752920.064
renal tubule developmentGO:0061326640.064
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.062
locomotory behaviorGO:00076261760.062
neuronal stem cell maintenanceGO:009715040.062
organelle fissionGO:00482853400.061
nephron tubule morphogenesisGO:007207830.061
transcription from rna polymerase ii promoterGO:00063663680.061
response to external biotic stimulusGO:00432072930.060
positive regulation of nitrogen compound metabolic processGO:00511733540.060
regulation of axon extensionGO:003051680.059
proximal distal pattern formationGO:0009954150.059
immune effector processGO:0002252980.059
medulla oblongata developmentGO:002155020.059
morphogenesis of embryonic epitheliumGO:0016331940.058
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.057
negative regulation of nervous system developmentGO:0051961920.056
smoothened signaling pathwayGO:0007224490.056
cellular amine metabolic processGO:0044106120.056
enzyme linked receptor protein signaling pathwayGO:00071671790.056
brain morphogenesisGO:0048854160.055
protein complex assemblyGO:00064612000.055
cell deathGO:00082192790.055
negative regulation of cell differentiationGO:00455961430.054
imaginal disc derived appendage morphogenesisGO:00351143950.053
respiratory system developmentGO:00605412130.053
neural retina developmentGO:000340740.051
taxisGO:00423303040.051
positive regulation of nucleic acid templated transcriptionGO:19035082660.050
lateral inhibitionGO:00463312060.050
negative regulation of glial cell proliferationGO:006025360.050
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.050
cell maturationGO:00484691440.049
wing disc morphogenesisGO:00074723440.048
digestive tract morphogenesisGO:00485461270.048
adult behaviorGO:00305341370.047
retina morphogenesis in camera type eyeGO:006004220.047
neuroblast differentiationGO:0014016290.047
positive regulation of developmental processGO:00510941430.047
r8 cell fate commitmentGO:000746060.046
axon extension involved in axon guidanceGO:0048846100.046
positive regulation of cellular biosynthetic processGO:00313283160.045
positive regulation of transcription dna templatedGO:00458932660.045
erbb signaling pathwayGO:0038127580.044
response to other organismGO:00517072930.043
imaginal disc derived appendage developmentGO:00487373990.043
response to abiotic stimulusGO:00096283410.042
circadian rhythmGO:00076231050.042
small molecule metabolic processGO:00442813050.042
embryonic morphogenesisGO:00485982060.042
imaginal disc pattern formationGO:0007447910.042
positive regulation of biosynthetic processGO:00098913160.041
developmental maturationGO:00217001720.040
body morphogenesisGO:001017120.040
neuroblast fate commitmentGO:0014017190.040
epidermis developmentGO:0008544650.040
protein complex biogenesisGO:00702712010.039
cell growthGO:00160491080.039
negative regulation of cellular metabolic processGO:00313243820.039
neural precursor cell proliferationGO:0061351750.039
regulation of glial cell proliferationGO:0060251110.039
deathGO:00162652840.039
humoral immune responseGO:00069591170.039
malpighian tubule morphogenesisGO:0007443440.039
central nervous system developmentGO:00074172010.038
positive regulation of gene expressionGO:00106282900.038
neuron apoptotic processGO:0051402170.038
regulation of cell cycle processGO:00105641810.038
regulation of gliogenesisGO:0014013110.037
multi organism reproductive behaviorGO:00447051210.037
positive regulation of signalingGO:00230562430.037
cellular component assembly involved in morphogenesisGO:00109271510.037
positive regulation of rna biosynthetic processGO:19026802660.036
ensheathment of neuronsGO:0007272100.036
negative regulation of cellular biosynthetic processGO:00313272770.036
oenocyte developmentGO:000743880.035
organonitrogen compound metabolic processGO:19015643180.034
oxoacid metabolic processGO:00434361030.034
hindbrain developmentGO:003090220.034
regulation of production of molecular mediator of immune responseGO:0002700440.034
regulation of erbb signaling pathwayGO:1901184420.034
spinal cord developmentGO:002151010.034
negative regulation of developmental processGO:00510932010.033
embryonic epithelial tube formationGO:000183860.033
negative regulation of programmed cell deathGO:0043069720.033
regulation of intracellular signal transductionGO:19025312360.033
peripheral nervous system neuron differentiationGO:004893480.033
negative regulation of stem cell differentiationGO:200073780.032
negative regulation of erbb signaling pathwayGO:1901185290.032
neuron projection extensionGO:1990138320.032
gland developmentGO:00487321910.032
regulation of response to external stimulusGO:00321011150.032
renal system developmentGO:0072001720.032
organic acid metabolic processGO:00060821030.031
regulation of cellular response to stressGO:0080135890.031
retina development in camera type eyeGO:006004140.031
nephron developmentGO:007200630.030
positive regulation of cell cycleGO:0045787430.030
positive regulation of mitotic cell cycleGO:0045931340.030
startle responseGO:0001964160.030
epithelial tube formationGO:007217570.030
striated muscle cell differentiationGO:0051146900.030
regulation of catalytic activityGO:00507901850.029
regulation of localizationGO:00328792750.029
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.029
salivary gland morphogenesisGO:00074351450.029
dendrite developmentGO:00163582040.029
positive regulation of intracellular signal transductionGO:19025331160.028
neuroblast fate determinationGO:0007400120.028
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.028
regulation of bmp signaling pathwayGO:0030510230.028
dedifferentiationGO:004369620.028
dorsal ventral pattern formation imaginal discGO:0007450510.028
embryonic hindgut morphogenesisGO:0048619480.028
open tracheal system developmentGO:00074242040.028
negative regulation of rna metabolic processGO:00512532510.027
negative regulation of mitotic cell cycleGO:00459301090.027
camera type eye morphogenesisGO:004859320.027
positive regulation of neural precursor cell proliferationGO:200017980.027
regulation of axon extension involved in axon guidanceGO:004884140.027
positive regulation of macromolecule biosynthetic processGO:00105572830.027
wing disc pattern formationGO:0035222660.027
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.026
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.026
protein modification processGO:00362114380.026
regulation of axonogenesisGO:0050770320.025
compound eye photoreceptor developmentGO:0042051780.024
adult locomotory behaviorGO:0008344760.024
cell divisionGO:00513012480.024
post embryonic appendage morphogenesisGO:00351203850.024
positive regulation of rna metabolic processGO:00512542710.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.024
regulation of axon guidanceGO:1902667100.024
organelle assemblyGO:00709251980.024
ovarian follicle cell developmentGO:00307072480.023
endocytosisGO:00068973100.023
stem cell proliferationGO:0072089880.023
response to bacteriumGO:00096171980.023
positive regulation of cell communicationGO:00106472500.023
negative regulation of rna biosynthetic processGO:19026792400.023
apoptotic processGO:00069151590.023
larval locomotory behaviorGO:0008345270.022
neurological system processGO:00508773580.022
regulation of organelle organizationGO:00330431960.022
muscle cell differentiationGO:00426921030.022
mesoderm developmentGO:0007498780.022
regulation of cell cycleGO:00517262910.022
positive regulation of phosphorus metabolic processGO:00105621390.022
negative regulation of gliogenesisGO:001401460.022
muscle cell developmentGO:0055001500.021
regulation of ovipositionGO:0046662140.021
regulation of cellular component sizeGO:0032535980.021
positive regulation of catabolic processGO:00098961050.021
larval developmentGO:00021641040.021
regulation of antimicrobial peptide productionGO:0002784440.021
rhythmic processGO:00485111060.021
positive regulation of molecular functionGO:00440931360.021
positive regulation of nervous system developmentGO:0051962690.020
developmental cell growthGO:0048588520.020
hindgut morphogenesisGO:0007442580.020
phosphorylationGO:00163102940.020
regulation of cell sizeGO:0008361630.020
positive regulation of neuroblast proliferationGO:000205270.020
epithelial cell proliferation involved in malpighian tubule morphogenesisGO:0061331110.020
response to decreased oxygen levelsGO:0036293580.020
hematopoietic progenitor cell differentiationGO:000224410.020
response to biotic stimulusGO:00096072940.020
exocrine system developmentGO:00352721620.020
compound eye cone cell fate commitmentGO:004267650.020
neuron fate commitmentGO:0048663500.019
regulation of immune system processGO:00026821760.019
columnar cuboidal epithelial cell developmentGO:00020662490.019
cellular protein modification processGO:00064644380.019
neuromuscular processGO:0050905210.019
regulation of multi organism processGO:00439001310.019
single organism intracellular transportGO:19025822070.019
regulation of cell deathGO:00109411730.019
skin developmentGO:0043588650.019
establishment of ommatidial planar polarityGO:0042067490.019
regulation of epidermal cell differentiationGO:004560430.019
defense response to bacteriumGO:00427421780.018
camera type eye photoreceptor cell differentiationGO:006021920.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.018
cell adhesionGO:00071551360.018
regulation of molecular functionGO:00650092170.018
kidney developmentGO:000182230.018
syncytium formation by plasma membrane fusionGO:0000768430.018
amine metabolic processGO:0009308120.018
cell cell signaling involved in cell fate commitmentGO:00451682100.017
hematopoietic or lymphoid organ developmentGO:0048534570.017
macromolecule catabolic processGO:00090571610.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010090.017
kidney morphogenesisGO:006099330.017
salivary gland developmentGO:00074311620.017
regulation of compound eye cone cell fate specificationGO:004268240.017
glial cell proliferationGO:0014009130.017
head developmentGO:00603221350.016
cellular catabolic processGO:00442483720.016
tube formationGO:0035148210.016
cellular response to dna damage stimulusGO:00069742230.016
positive regulation of protein metabolic processGO:00512471280.016
regulation of cellular protein metabolic processGO:00322682430.016
peripheral nervous system developmentGO:0007422520.016
regulation of immune effector processGO:0002697520.016
actin filament based processGO:00300292200.016
regulation of phosphorus metabolic processGO:00511742100.016
anterior posterior pattern specificationGO:00099521360.015
positive regulation of catalytic activityGO:00430851180.015
gastrulation involving germ band extensionGO:0010004360.015
circadian behaviorGO:0048512760.015
small gtpase mediated signal transductionGO:0007264880.015
eggshell formationGO:00307031050.015
vesicle mediated transportGO:00161923810.015
regulation of hemocyte proliferationGO:0035206370.015
gastrulation with mouth forming firstGO:0001703360.015
wing disc dorsal ventral pattern formationGO:0048190470.015
r8 cell differentiationGO:0045465130.014
regulation of reproductive processGO:2000241540.014
morphogenesis of a polarized epitheliumGO:0001738930.014
Fly
regulation of antimicrobial peptide biosynthetic processGO:0002805380.014
central nervous system neuron developmentGO:002195480.014
negative regulation of neuron differentiationGO:0045665160.014
negative regulation of apoptotic processGO:0043066630.014
immune responseGO:00069552460.014
regulation of apoptotic processGO:00429811300.014
programmed cell deathGO:00125012570.014
regulation of phosphate metabolic processGO:00192202100.014
growthGO:00400073590.013
retinal cone cell differentiationGO:004267020.013
muscle organ developmentGO:00075171270.013
wound healingGO:0042060750.013
phagocytosisGO:00069092150.013
positive regulation of cell differentiationGO:0045597640.013
nephron morphogenesisGO:007202830.013
regulation of nuclear divisionGO:0051783580.013
chemotaxisGO:00069352490.013
regulation of mitotic cell cycleGO:00073461900.013
cell recognitionGO:00080371020.013
central nervous system neuron differentiationGO:002195380.013
positive regulation of protein serine threonine kinase activityGO:0071902150.012
regulation of chemotaxisGO:0050920120.012
mesenchymal cell differentiationGO:004876210.012
germ line stem cell maintenanceGO:0030718500.012
macromolecular complex assemblyGO:00650032560.012
regulation of programmed cell deathGO:00430671520.012
chromosome organizationGO:00512763600.012
regulation of response to dna damage stimulusGO:2001020230.012
neuron recognitionGO:00080381010.012
multi organism behaviorGO:00517051750.012
negative regulation of cell deathGO:0060548810.012
regulation of cell proliferationGO:00421271630.012
antimicrobial peptide biosynthetic processGO:0002777380.012
axon guidanceGO:00074112330.012
response to oxygen levelsGO:0070482590.012
regulation of anatomical structure morphogenesisGO:00226032420.012
ommatidial rotationGO:0016318200.011
positive regulation of neuron apoptotic processGO:004352510.011
oenocyte differentiationGO:000174280.011
locomotor rhythmGO:0045475560.011
protein phosphorylationGO:00064681690.011
defense response to other organismGO:00985422250.011
rhythmic behaviorGO:0007622760.011
antimicrobial humoral responseGO:0019730990.011
organic substance transportGO:00717022570.011
negative regulation of cell cycleGO:00457861160.011
transmission of nerve impulseGO:0019226120.011
protein modification by small protein conjugation or removalGO:00706471060.011
regulation of gene expression epigeneticGO:00400291280.011
imaginal disc derived wing vein specificationGO:0007474480.011
jak stat cascadeGO:0007259490.011
cellular response to organic substanceGO:00713101320.011
negative regulation of cell cycle processGO:00109481090.010
negative regulation of cell divisionGO:0051782170.010
single organism behaviorGO:00447083910.010
regulation of kinase activityGO:0043549530.010
regulation of humoral immune responseGO:0002920510.010
positive regulation of transferase activityGO:0051347260.010
regulation of jak stat cascadeGO:0046425430.010
regulation of developmental growthGO:00486381740.010
regulation of cell fate specificationGO:0042659270.010
glandular epithelial cell differentiationGO:000206710.010
negative regulation of cellular component organizationGO:00511291080.010

m4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
dysostosisDOID:193400.517
bone diseaseDOID:008000100.517
disease of anatomical entityDOID:700.517
bone development diseaseDOID:008000600.517
connective tissue diseaseDOID:6500.517
musculoskeletal system diseaseDOID:1700.517
spondylocostal dysostosisDOID:005056800.517