Drosophila melanogaster

46 known processes

Ptp4E (Dmel_CG6899)

Protein tyrosine phosphatase 4E

(Aliases: PTP4E,PtP4E,CG6899,DPTP4E,Dmel\CG6899,R-PTP 4E,CT21187)

Ptp4E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.335
cholesterol homeostasisGO:004263230.106
alcohol metabolic processGO:0006066250.097
positive regulation of response to stimulusGO:00485843230.095
Human Mouse
sterol homeostasisGO:005509240.093
single organism behaviorGO:00447083910.086
Fly
actomyosin structure organizationGO:0031032560.082
chemical homeostasisGO:0048878920.079
vesicle mediated transportGO:00161923810.075
cell migrationGO:00164772380.074
Human Mouse
cell projection assemblyGO:0030031940.073
Mouse
morphogenesis of an epitheliumGO:00020092760.069
lateral inhibitionGO:00463312060.064
protein complex assemblyGO:00064612000.062
cell cell signaling involved in cell fate commitmentGO:00451682100.062
homeostatic processGO:00425921990.059
cell deathGO:00082192790.059
tube developmentGO:00352952440.055
protein modification processGO:00362114380.053
Human Mouse Rat Fly
embryonic morphogenesisGO:00485982060.051
Mouse
regulation of protein metabolic processGO:00512462560.048
Human Mouse
male gamete generationGO:00482322010.046
deathGO:00162652840.045
oxidation reduction processGO:00551141230.045
rna processingGO:00063961470.045
regulation of apoptotic processGO:00429811300.042
positive regulation of cell communicationGO:00106472500.042
Human
organelle assemblyGO:00709251980.042
spermatid developmentGO:0007286980.041
regulation of cellular amino acid metabolic processGO:000652100.041
cellular lipid metabolic processGO:0044255830.040
programmed cell deathGO:00125012570.039
spermatid differentiationGO:00485151140.039
axonogenesisGO:00074092900.038
apoptotic processGO:00069151590.038
response to woundingGO:0009611940.038
Mouse
positive regulation of signalingGO:00230562430.037
Human
embryonic development via the syncytial blastodermGO:00017001480.037
regulation of molecular functionGO:00650092170.037
Human Mouse
lipid metabolic processGO:00066291210.036
protein maturationGO:0051604710.035
actin cytoskeleton organizationGO:00300362060.035
embryo development ending in birth or egg hatchingGO:00097921520.035
negative regulation of cellular protein metabolic processGO:0032269850.035
Human Mouse
regulation of programmed cell deathGO:00430671520.035
regulation of cellular ketone metabolic processGO:001056530.035
regulation of localizationGO:00328792750.035
Human Mouse
cellular ketone metabolic processGO:0042180240.034
organic hydroxy compound metabolic processGO:1901615830.034
tissue morphogenesisGO:00487292970.034
mrna splicing via spliceosomeGO:0000398730.033
adult behaviorGO:00305341370.032
macromolecular complex assemblyGO:00650032560.032
protein complex biogenesisGO:00702712010.030
sister chromatid segregationGO:0000819920.030
cellular response to dna damage stimulusGO:00069742230.030
regulation of cellular amine metabolic processGO:003323830.029
cellular protein modification processGO:00064644380.029
Human Mouse Rat Fly
cell adhesionGO:00071551360.028
Human Mouse
carboxylic acid metabolic processGO:0019752920.028
regulation of catalytic activityGO:00507901850.028
Human Mouse
pigment metabolic processGO:0042440840.027
cell maturationGO:00484691440.027
response to abiotic stimulusGO:00096283410.027
Mouse
regulation of cellular localizationGO:00603411360.027
proteolysisGO:00065081920.026
regulation of immune system processGO:00026821760.026
Human Mouse
positive regulation of signal transductionGO:00099672230.026
Human
negative regulation of cell communicationGO:00106482230.025
Human Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.025
negative regulation of response to stimulusGO:00485852580.025
Human Mouse
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.025
Human Mouse
response to monosaccharideGO:003428440.025
regionalizationGO:00030024160.024
actin filament based processGO:00300292200.024
cellular component assembly involved in morphogenesisGO:00109271510.024
regulation of cell deathGO:00109411730.024
regulation of notch signaling pathwayGO:00085931000.024
cation transmembrane transportGO:0098655880.024
catabolic processGO:00090564090.024
wound healingGO:0042060750.023
Mouse
mrna metabolic processGO:00160711240.023
cellular amine metabolic processGO:0044106120.023
organic acid metabolic processGO:00060821030.023
anterior posterior pattern specificationGO:00099521360.023
actin filament organizationGO:00070151260.022
morphogenesis of embryonic epitheliumGO:0016331940.022
oxoacid metabolic processGO:00434361030.022
positive regulation of gtpase activityGO:0043547430.022
axon guidanceGO:00074112330.021
organonitrogen compound metabolic processGO:19015643180.021
immune system processGO:00023763470.021
Human Mouse
tube morphogenesisGO:00352391910.021
growthGO:00400073590.021
Human
regulation of intracellular signal transductionGO:19025312360.021
Human Mouse
positive regulation of programmed cell deathGO:0043068620.020
mrna processingGO:00063971040.020
regulation of response to stressGO:00801342000.020
Mouse
negative regulation of protein metabolic processGO:0051248850.020
Human Mouse
monovalent inorganic cation transportGO:0015672400.020
negative regulation of gene expressionGO:00106293870.020
endocytosisGO:00068973100.019
oocyte differentiationGO:00099941450.019
developmental programmed cell deathGO:00106231380.019
sensory perceptionGO:00076001960.019
Mouse
regulation of cysteine type endopeptidase activityGO:2000116270.019
enzyme linked receptor protein signaling pathwayGO:00071671790.019
Human Mouse
amine metabolic processGO:0009308120.018
exocrine system developmentGO:00352721620.018
cellular response to chemical stimulusGO:00708871990.018
Human Mouse
endoderm formationGO:000170630.018
notch signaling pathwayGO:00072191200.018
regulation of cell proliferationGO:00421271630.017
Human Mouse
spindle organizationGO:00070512530.017
cellular homeostasisGO:0019725800.017
cellular amino acid metabolic processGO:0006520610.017
establishment of localization in cellGO:00516494020.017
regulation of anatomical structure morphogenesisGO:00226032420.017
regulation of cell differentiationGO:00455953020.016
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.016
regulation of hydrolase activityGO:0051336970.016
protein secretionGO:0009306450.016
positive regulation of nucleoside metabolic processGO:0045979470.016
intracellular signal transductionGO:00355563000.016
Human Mouse
spermatogenesisGO:00072832000.016
cellular macromolecule catabolic processGO:00442651360.016
regulation of cellular protein metabolic processGO:00322682430.015
Human Mouse
single organism cellular localizationGO:19025801800.015
cell motilityGO:00488702510.015
Human Mouse
metal ion transportGO:0030001740.015
regulation of phosphate metabolic processGO:00192202100.015
Human Mouse
protein phosphorylationGO:00064681690.015
Human Mouse
eye developmentGO:00016543230.015
regulation of proteolysisGO:0030162870.015
membrane organizationGO:00610241120.015
regulation of phosphorus metabolic processGO:00511742100.015
Human Mouse
immune response regulating signaling pathwayGO:000276420.015
Human Mouse
peptidyl amino acid modificationGO:00181931050.014
rna localizationGO:00064031150.014
imaginal disc derived wing morphogenesisGO:00074763370.014
regulation of phosphorylationGO:00423251470.014
Human Mouse
negative regulation of immune system processGO:0002683500.014
Human Mouse
regulation of establishment of protein localizationGO:0070201610.014
positive regulation of cellular component biogenesisGO:0044089800.014
Human
secondary metabolic processGO:0019748750.014
regulation of transportGO:00510491810.014
smoothened signaling pathwayGO:0007224490.014
agingGO:00075681430.014
positive regulation of immune system processGO:0002684680.013
Human Mouse
rna splicingGO:0008380830.013
biological adhesionGO:00226101380.013
Human Mouse
phagocytosisGO:00069092150.013
response to hexoseGO:000974630.013
tissue deathGO:00162711020.013
positive regulation of purine nucleotide catabolic processGO:0033123460.013
negative regulation of signal transductionGO:00099682060.013
Human Mouse
metal ion homeostasisGO:0055065440.013
protein modification by small protein conjugationGO:0032446790.013
small gtpase mediated signal transductionGO:0007264880.013
cation transportGO:00068121100.013
salivary gland developmentGO:00074311620.013
chemotaxisGO:00069352490.012
compound eye developmentGO:00487493070.012
aromatic compound catabolic processGO:00194391660.012
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.012
purine nucleotide metabolic processGO:00061631460.012
organic substance catabolic processGO:19015753080.012
regulation of reproductive processGO:2000241540.012
nucleobase containing compound catabolic processGO:00346551650.012
single organism carbohydrate metabolic processGO:0044723720.012
oocyte developmentGO:00485991240.012
digestive system developmentGO:00551231490.012
kidney developmentGO:000182230.012
Human Mouse
intracellular mrna localization involved in pattern specification processGO:0060810560.012
negative regulation of catalytic activityGO:0043086420.012
Human Mouse
retina development in camera type eyeGO:006004140.011
developmental maturationGO:00217001720.011
response to lipopolysaccharideGO:003249640.011
cell proliferationGO:00082832990.011
Human Mouse
dephosphorylationGO:0016311510.011
Human Mouse Rat Fly
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.011
peripheral nervous system developmentGO:0007422520.011
regulation of peptidase activityGO:0052547390.011
pole plasm oskar mrna localizationGO:0045451460.011
neurological system processGO:00508773580.011
Mouse Fly
protein localizationGO:00081042840.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
negative regulation of multicellular organismal processGO:00512411420.011
Rat
cellular chemical homeostasisGO:0055082400.011
response to extracellular stimulusGO:00099911160.011
rna splicing via transesterification reactionsGO:0000375730.011
body morphogenesisGO:001017120.011
cellular macromolecular complex assemblyGO:00346221530.011
response to nutrient levelsGO:00316671140.011
protein transportGO:00150311550.011
ion transportGO:00068111450.011
response to light stimulusGO:00094161240.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
Human
positive regulation of lipid metabolic processGO:004583440.010
camera type eye developmentGO:004301040.010
salivary gland morphogenesisGO:00074351450.010
cellular response to transforming growth factor beta stimulusGO:0071560180.010
cell divisionGO:00513012480.010
cell cell junction organizationGO:0045216550.010
Human Mouse
response to radiationGO:00093141550.010
regulation of membrane potentialGO:0042391350.010

Ptp4E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
Human
urinary system diseaseDOID:1800.020
Human
sensory system diseaseDOID:005015500.016
eye and adnexa diseaseDOID:149200.016
nervous system diseaseDOID:86300.016