IMP: Integrative Multi-species Prediction

Drosophila melanogaster

133 known processes

dome (Dmel_CG14226)

domeless

(Aliases: mom,l(1)G0321,l(1)G0405,Dmel\CG14226,l(1)G0282,l(1)G0218,CT33841,l(1)G0217,anon-18DEb,l(1)G0264,Dome,DOME,142932_at,l(1)G0441,l(1)G0468,vsp,l(1)G0367,CG14226)

Entrez: 32976
FLYBASE: FBgn0043903
UniProtKB: Q9VWE0

Process Predictions
Disease Predictions

dome biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
border follicle cell migration	GO:0007298	113	1.000
columnar cuboidal epithelial cell differentiation	GO:0002065	256	1.000
epithelial cell differentiation	GO:0030855	322	1.000
ovarian follicle cell migration	GO:0007297	121	1.000
ovarian follicle cell development	GO:0030707	248	1.000
female germ line cyst formation	GO:0048135	42	0.999
germ line cyst formation	GO:0048134	44	0.998
tissue migration	GO:0090130	155	0.997
germarium derived female germ line cyst formation	GO:0030727	42	0.997
epithelial cell migration	GO:0010631	148	0.997
epithelium migration	GO:0090132	148	0.996
columnar cuboidal epithelial cell development	GO:0002066	249	0.995
cell proliferation	GO:0008283	299	0.995
muscle structure development	GO:0061061	224	0.991
epithelial cell development	GO:0002064	274	0.991
cell motility	GO:0048870	251	0.979
cell migration	GO:0016477	238	0.967
long term memory	GO:0007616	62	0.966
hindgut morphogenesis	GO:0007442	58	0.945
germarium derived egg chamber formation	GO:0007293	101	0.924
ameboidal type cell migration	GO:0001667	151	0.916
positive regulation of cell communication	GO:0010647	250	0.912
jak stat cascade	GO:0007259	49	0.866
negative regulation of transcription dna templated	GO:0045892	237	0.866
positive regulation of biosynthetic process	GO:0009891	316	0.857
embryonic development via the syncytial blastoderm	GO:0001700	148	0.848
blastoderm segmentation	GO:0007350	159	0.836
response to external biotic stimulus	GO:0043207	293	0.833
defense response	GO:0006952	300	0.829
response to bacterium	GO:0009617	198	0.826
circadian rhythm	GO:0007623	105	0.822
positive regulation of rna metabolic process	GO:0051254	271	0.816
localization of cell	GO:0051674	257	0.800
defense response to other organism	GO:0098542	225	0.785
immune response	GO:0006955	246	0.773
developmental growth	GO:0048589	280	0.769
intracellular signal transduction	GO:0035556	300	0.762
positive regulation of response to stimulus	GO:0048584	323	0.740
negative regulation of cellular biosynthetic process	GO:0031327	277	0.720
positive regulation of signaling	GO:0023056	243	0.710
compound eye morphogenesis	GO:0001745	249	0.705
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.704
respiratory system development	GO:0060541	213	0.695
oocyte construction	GO:0007308	112	0.682
regulation of cell differentiation	GO:0045595	302	0.681
meiotic nuclear division	GO:0007126	151	0.674
digestive tract development	GO:0048565	149	0.672
positive regulation of transcription dna templated	GO:0045893	266	0.672
positive regulation of gene expression	GO:0010628	290	0.669
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.655
embryonic pattern specification	GO:0009880	174	0.650
hindgut development	GO:0061525	58	0.647
open tracheal system development	GO:0007424	204	0.637
actin filament based process	GO:0030029	220	0.633
transcription from rna polymerase ii promoter	GO:0006366	368	0.626
memory	GO:0007613	94	0.616
regulation of growth	GO:0040008	233	0.598
axon development	GO:0061564	297	0.594
tissue morphogenesis	GO:0048729	297	0.583
sensory organ morphogenesis	GO:0090596	260	0.579
eye morphogenesis	GO:0048592	260	0.577
regulation of anatomical structure morphogenesis	GO:0022603	242	0.567
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.566
defense response to bacterium	GO:0042742	178	0.537
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.522
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.508
urogenital system development	GO:0001655	72	0.504
epithelial cell proliferation	GO:0050673	15	0.483
compound eye photoreceptor cell differentiation	GO:0001751	140	0.477
digestive tract morphogenesis	GO:0048546	127	0.470
regionalization	GO:0003002	416	0.455
multi organism reproductive behavior	GO:0044705	121	0.454
positive regulation of cellular biosynthetic process	GO:0031328	316	0.451
glycosyl compound metabolic process	GO:1901657	127	0.448
positive regulation of macromolecule metabolic process	GO:0010604	405	0.442
muscle tissue development	GO:0060537	30	0.438
multi multicellular organism process	GO:0044706	123	0.435
negative regulation of cell communication	GO:0010648	223	0.430
hemopoiesis	GO:0030097	46	0.430
regulation of stem cell proliferation	GO:0072091	40	0.427
macromolecular complex assembly	GO:0065003	256	0.423
locomotory behavior	GO:0007626	176	0.421
oocyte development	GO:0048599	124	0.420
response to biotic stimulus	GO:0009607	294	0.412
innate immune response	GO:0045087	144	0.411
negative regulation of rna biosynthetic process	GO:1902679	240	0.411
photoreceptor cell differentiation	GO:0046530	170	0.408
embryo development ending in birth or egg hatching	GO:0009792	152	0.402
regulation of response to stress	GO:0080134	200	0.400
regulation of cell death	GO:0010941	173	0.391
wing disc morphogenesis	GO:0007472	344	0.387
negative regulation of rna metabolic process	GO:0051253	251	0.387
negative regulation of response to stimulus	GO:0048585	258	0.371
appendage development	GO:0048736	401	0.363
hematopoietic or lymphoid organ development	GO:0048534	57	0.363
learning or memory	GO:0007611	141	0.358
striated muscle tissue development	GO:0014706	27	0.357
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.345
chemotaxis	GO:0006935	249	0.331
multicellular organismal reproductive behavior	GO:0033057	110	0.328
organonitrogen compound metabolic process	GO:1901564	318	0.318
regulation of notch signaling pathway	GO:0008593	100	0.311
positive regulation of signal transduction	GO:0009967	223	0.309
biological adhesion	GO:0022610	138	0.306
positive regulation of cell proliferation	GO:0008284	47	0.299
morphogenesis of an epithelium	GO:0002009	276	0.297
chromosome organization	GO:0051276	360	0.284
epithelial structure maintenance	GO:0010669	17	0.282
regulation of cell morphogenesis	GO:0022604	163	0.277
glycoprotein metabolic process	GO:0009100	41	0.269
protein complex assembly	GO:0006461	200	0.265
death	GO:0016265	284	0.262
regulation of nervous system development	GO:0051960	248	0.259
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.253
response to other organism	GO:0051707	293	0.246
circadian behavior	GO:0048512	76	0.243
regulation of cell shape	GO:0008360	113	0.243
negative regulation of apoptotic process	GO:0043066	63	0.236
striated muscle cell differentiation	GO:0051146	90	0.233
axonogenesis	GO:0007409	290	0.229
axis specification	GO:0009798	167	0.225
oocyte axis specification	GO:0007309	108	0.222
establishment or maintenance of cell polarity	GO:0007163	167	0.221
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.212
small molecule metabolic process	GO:0044281	305	0.209
multicellular organismal aging	GO:0010259	140	0.207
dna metabolic process	GO:0006259	227	0.205
growth	GO:0040007	359	0.204
multicellular organismal homeostasis	GO:0048871	41	0.204
neuron projection guidance	GO:0097485	241	0.204
appendage morphogenesis	GO:0035107	397	0.202
dendrite morphogenesis	GO:0048813	199	0.201
response to organic cyclic compound	GO:0014070	89	0.198
eye antennal disc morphogenesis	GO:0007455	34	0.197
nucleobase containing small molecule metabolic process	GO:0055086	174	0.196
protein modification process	GO:0036211	438	0.196
negative regulation of signal transduction	GO:0009968	206	0.195
actin cytoskeleton organization	GO:0030036	206	0.188
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.186
cell death	GO:0008219	279	0.182
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.182
cuticle development	GO:0042335	86	0.180
gland development	GO:0048732	191	0.179
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.179
regulation of immune system process	GO:0002682	176	0.175
imaginal disc derived wing morphogenesis	GO:0007476	337	0.173
kidney development	GO:0001822	3	0.172
regulation of phosphorus metabolic process	GO:0051174	210	0.171
reproductive behavior	GO:0019098	122	0.169
negative regulation of developmental process	GO:0051093	201	0.168
digestive system development	GO:0055123	149	0.166
cognition	GO:0050890	141	0.166
dendrite development	GO:0016358	204	0.165
carbohydrate derivative metabolic process	GO:1901135	217	0.164
chitin based cuticle development	GO:0040003	49	0.162
carbohydrate derivative catabolic process	GO:1901136	118	0.162
cell maturation	GO:0048469	144	0.161
positive regulation of rna biosynthetic process	GO:1902680	266	0.160
cellular protein modification process	GO:0006464	438	0.156
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.155
cellular macromolecule localization	GO:0070727	220	0.150
purine nucleoside catabolic process	GO:0006152	112	0.149
reproductive system development	GO:0061458	74	0.148
negative regulation of multicellular organismal process	GO:0051241	142	0.148
covalent chromatin modification	GO:0016569	106	0.147
eye development	GO:0001654	323	0.145
stem cell proliferation	GO:0072089	88	0.145
protein complex biogenesis	GO:0070271	201	0.144
rhythmic process	GO:0048511	106	0.141
malpighian tubule morphogenesis	GO:0007443	44	0.140
ovarian follicle cell stalk formation	GO:0030713	17	0.138
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.137
single organism intracellular transport	GO:1902582	207	0.136
locomotor rhythm	GO:0045475	56	0.136
regulation of wnt signaling pathway	GO:0030111	68	0.136
multi organism behavior	GO:0051705	175	0.135
determination of adult lifespan	GO:0008340	137	0.134
regulation of erbb signaling pathway	GO:1901184	42	0.133
tissue homeostasis	GO:0001894	36	0.128
phosphorylation	GO:0016310	294	0.126
immune system process	GO:0002376	347	0.124
foregut morphogenesis	GO:0007440	10	0.123
positive regulation of phosphate metabolic process	GO:0045937	139	0.123
peptidyl lysine modification	GO:0018205	57	0.122
negative regulation of heart induction by canonical wnt signaling pathway	GO:0003136	3	0.121
regulation of intracellular signal transduction	GO:1902531	236	0.121
catabolic process	GO:0009056	409	0.121
regulation of cell proliferation	GO:0042127	163	0.120
positive regulation of axon guidance	GO:1902669	1	0.118
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.118
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.115
cytokinesis	GO:0000910	90	0.115
regulation of apoptotic process	GO:0042981	130	0.113
internal protein amino acid acetylation	GO:0006475	38	0.113
endocytosis	GO:0006897	310	0.112
positive regulation of multicellular organismal process	GO:0051240	143	0.110
post embryonic appendage morphogenesis	GO:0035120	385	0.109
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.109
morphogenesis of embryonic epithelium	GO:0016331	94	0.109
oocyte differentiation	GO:0009994	145	0.108
antimicrobial humoral response	GO:0019730	99	0.107
camera type eye development	GO:0043010	4	0.107
nucleotide metabolic process	GO:0009117	161	0.107
purine nucleotide metabolic process	GO:0006163	146	0.105
nucleoside catabolic process	GO:0009164	112	0.103
regulation of multicellular organismal development	GO:2000026	414	0.103
positive regulation of immune system process	GO:0002684	68	0.103
negative regulation of cell differentiation	GO:0045596	143	0.101
embryonic hemopoiesis	GO:0035162	26	0.101
meiotic cell cycle process	GO:1903046	132	0.100
regulation of epithelial cell differentiation	GO:0030856	4	0.099
neuron fate commitment	GO:0048663	50	0.099
positive regulation of intracellular signal transduction	GO:1902533	116	0.098
regulation of innate immune response	GO:0045088	71	0.098
endosomal transport	GO:0016197	44	0.097
negative regulation of biosynthetic process	GO:0009890	277	0.097
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.096
programmed cell death	GO:0012501	257	0.094
regulation of organelle organization	GO:0033043	196	0.093
hemocyte differentiation	GO:0042386	38	0.092
spiracle morphogenesis open tracheal system	GO:0035277	22	0.091
oviposition	GO:0018991	19	0.091
nucleoside phosphate metabolic process	GO:0006753	162	0.090
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.089
imaginal disc growth	GO:0007446	37	0.089
response to light stimulus	GO:0009416	124	0.088
compound eye development	GO:0048749	307	0.088
segmentation	GO:0035282	207	0.086
nucleotide catabolic process	GO:0009166	109	0.085
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.084
erbb signaling pathway	GO:0038127	58	0.084
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.084
immune system development	GO:0002520	57	0.083
organic acid metabolic process	GO:0006082	103	0.083
mitotic cytokinesis	GO:0000281	50	0.082
mesoderm development	GO:0007498	78	0.082
photoreceptor cell development	GO:0042461	96	0.082
regulation of neural precursor cell proliferation	GO:2000177	35	0.081
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.080
immune effector process	GO:0002252	98	0.079
renal tubule development	GO:0061326	64	0.079
response to nitrogen compound	GO:1901698	90	0.078
purine ribonucleotide metabolic process	GO:0009150	145	0.078
chromatin organization	GO:0006325	207	0.077
wnt signaling pathway	GO:0016055	98	0.076
histone modification	GO:0016570	106	0.075
organic substance catabolic process	GO:1901575	308	0.074
cell growth	GO:0016049	108	0.074
mapk cascade	GO:0000165	107	0.073
proteolysis	GO:0006508	192	0.073
regulation of heart induction	GO:0090381	3	0.073
anatomical structure homeostasis	GO:0060249	97	0.072
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.072
taxis	GO:0042330	304	0.072
positive regulation of immune response	GO:0050778	63	0.072
positive regulation of cell differentiation	GO:0045597	64	0.071
histone h3 acetylation	GO:0043966	11	0.071
cell adhesion	GO:0007155	136	0.069
muscle organ development	GO:0007517	127	0.068
regulation of cytoskeleton organization	GO:0051493	89	0.068
ribose phosphate metabolic process	GO:0019693	145	0.067
axon guidance	GO:0007411	233	0.067
regulation of neuron differentiation	GO:0045664	103	0.067
negative regulation of gene expression	GO:0010629	387	0.066
homeostatic process	GO:0042592	199	0.066
nucleoside metabolic process	GO:0009116	127	0.066
development of primary sexual characteristics	GO:0045137	50	0.065
circadian regulation of gene expression	GO:0032922	5	0.065
defense response to gram negative bacterium	GO:0050829	94	0.065
response to wounding	GO:0009611	94	0.064
regulation of tube architecture open tracheal system	GO:0035152	68	0.063
aging	GO:0007568	143	0.063
oxoacid metabolic process	GO:0043436	103	0.063
regulation of organ morphogenesis	GO:2000027	78	0.062
negative regulation of cellular metabolic process	GO:0031324	382	0.062
purine containing compound catabolic process	GO:0072523	112	0.060
r3 r4 cell differentiation	GO:0048056	12	0.060
vesicle mediated transport	GO:0016192	381	0.060
morphogenesis of follicular epithelium	GO:0016333	36	0.060
nucleoside triphosphate metabolic process	GO:0009141	120	0.058
notch signaling pathway	GO:0007219	120	0.058
cellular protein localization	GO:0034613	160	0.058
neurological system process	GO:0050877	358	0.058
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.058
response to lipopolysaccharide	GO:0032496	4	0.057
striated muscle cell development	GO:0055002	50	0.057
pseudocleavage involved in syncytial blastoderm formation	GO:0030589	9	0.057
cellular response to external stimulus	GO:0071496	66	0.055
eggshell formation	GO:0030703	105	0.054
body morphogenesis	GO:0010171	2	0.054
chromatin modification	GO:0016568	147	0.053
protein targeting to nucleus	GO:0044744	51	0.052
establishment of protein localization to organelle	GO:0072594	62	0.052
developmental maturation	GO:0021700	172	0.052
regulation of defense response	GO:0031347	102	0.052
negative regulation of smoothened signaling pathway	GO:0045879	16	0.052
regulation of developmental growth	GO:0048638	174	0.052
positive regulation of phosphorus metabolic process	GO:0010562	139	0.051
negative regulation of cell death	GO:0060548	81	0.051
gtp catabolic process	GO:0006184	72	0.051
small gtpase mediated signal transduction	GO:0007264	88	0.051
germarium derived female germ line cyst encapsulation	GO:0030708	8	0.051
gliogenesis	GO:0042063	80	0.050
protein localization to organelle	GO:0033365	82	0.050
regulation of ras protein signal transduction	GO:0046578	93	0.050
protein targeting	GO:0006605	64	0.050
positive regulation of response to external stimulus	GO:0032103	44	0.050
response to lipid	GO:0033993	38	0.049
regulation of hydrolase activity	GO:0051336	97	0.049
negative regulation of chromatin silencing	GO:0031936	9	0.049
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.049
response to endogenous stimulus	GO:0009719	119	0.048
cellular response to hormone stimulus	GO:0032870	44	0.048
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.048
regulation of protein metabolic process	GO:0051246	256	0.047
compound eye photoreceptor fate commitment	GO:0001752	36	0.047
regulation of nucleocytoplasmic transport	GO:0046822	35	0.047
sex differentiation	GO:0007548	81	0.047
larval development	GO:0002164	104	0.046
negative regulation of organelle organization	GO:0010639	56	0.046
nephron development	GO:0072006	3	0.045
renal tubule morphogenesis	GO:0061333	44	0.045
chemosensory behavior	GO:0007635	106	0.044
peptidyl tyrosine modification	GO:0018212	24	0.044
establishment of ommatidial planar polarity	GO:0042067	49	0.044
protein transport	GO:0015031	155	0.044
chromosome segregation	GO:0007059	157	0.044
purine ribonucleoside metabolic process	GO:0046128	127	0.043
positive regulation of defense response	GO:0031349	59	0.043
glial cell differentiation	GO:0010001	35	0.042
negative regulation of intracellular signal transduction	GO:1902532	57	0.042
negative regulation of cellular component organization	GO:0051129	108	0.042
regulation of neuroblast proliferation	GO:1902692	34	0.042
maintenance of gastrointestinal epithelium	GO:0030277	3	0.041
signal transduction by phosphorylation	GO:0023014	107	0.041
regulation of tube size	GO:0035150	46	0.040
cytoplasmic transport	GO:0016482	130	0.040
negative regulation of signaling	GO:0023057	219	0.040
positive regulation of developmental process	GO:0051094	143	0.039
cellular amino acid metabolic process	GO:0006520	61	0.039
detection of abiotic stimulus	GO:0009582	66	0.039
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.039
purine nucleoside metabolic process	GO:0042278	127	0.039
mating	GO:0007618	120	0.038
malpighian tubule development	GO:0072002	64	0.038
nucleoside phosphate catabolic process	GO:1901292	110	0.038
muscle cell differentiation	GO:0042692	103	0.038
regulation of phosphorylation	GO:0042325	147	0.038
phagocytosis	GO:0006909	215	0.038
skeletal muscle tissue development	GO:0007519	13	0.038
single organism nuclear import	GO:1902593	51	0.037
nucleoside triphosphate catabolic process	GO:0009143	108	0.037
mitotic nuclear division	GO:0007067	213	0.037
protein localization	GO:0008104	284	0.037
dorsal closure	GO:0007391	79	0.037
regulation of epithelial cell proliferation	GO:0050678	4	0.037
ribonucleoside metabolic process	GO:0009119	127	0.036
regulation of response to external stimulus	GO:0032101	115	0.036
eye photoreceptor cell differentiation	GO:0001754	145	0.036
spindle organization	GO:0007051	253	0.036
connective tissue development	GO:0061448	3	0.036
apoptotic process	GO:0006915	159	0.036
skeletal muscle organ development	GO:0060538	48	0.036
positive regulation of wnt signaling pathway	GO:0030177	25	0.036
regulation of protein phosphorylation	GO:0001932	64	0.036
glycosyl compound catabolic process	GO:1901658	112	0.036
regulation of tube size open tracheal system	GO:0035151	43	0.036
response to x ray	GO:0010165	8	0.035
positive regulation of fibroblast growth factor receptor signaling pathway	GO:0045743	5	0.035
regulation of phosphate metabolic process	GO:0019220	210	0.035
regulation of molecular function	GO:0065009	217	0.035
embryonic axis specification	GO:0000578	107	0.034
response to ecdysone	GO:0035075	34	0.034
amine metabolic process	GO:0009308	12	0.034
nucleobase containing compound catabolic process	GO:0034655	165	0.034
cellular component assembly involved in morphogenesis	GO:0010927	151	0.034
positive regulation of stem cell differentiation	GO:2000738	3	0.034
organic cyclic compound catabolic process	GO:1901361	168	0.034
single organism behavior	GO:0044708	391	0.034
mesenchymal cell differentiation	GO:0048762	1	0.033
response to nutrient levels	GO:0031667	114	0.033
cellular response to endogenous stimulus	GO:0071495	80	0.033
response to hormone	GO:0009725	45	0.033
cellular response to nitrogen compound	GO:1901699	51	0.033
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.033
response to alcohol	GO:0097305	95	0.032
protein localization to nucleus	GO:0034504	55	0.032
reproductive structure development	GO:0048608	74	0.032
carboxylic acid metabolic process	GO:0019752	92	0.032
positive regulation of cellular component organization	GO:0051130	156	0.032
regulation of cellular amino acid metabolic process	GO:0006521	0	0.032
regulation of cell division	GO:0051302	72	0.032
imaginal disc pattern formation	GO:0007447	91	0.031
embryonic hindgut morphogenesis	GO:0048619	48	0.031
guanosine containing compound catabolic process	GO:1901069	74	0.031
regulation of cellular catabolic process	GO:0031329	157	0.030
atp metabolic process	GO:0046034	49	0.030
response to organic substance	GO:0010033	284	0.030
positive regulation of innate immune response	GO:0045089	38	0.030
cellular catabolic process	GO:0044248	372	0.030
rna localization	GO:0006403	115	0.030
cellular response to organic substance	GO:0071310	132	0.029
mitotic spindle organization	GO:0007052	220	0.029
imaginal disc derived appendage development	GO:0048737	399	0.029
imaginal disc derived leg joint morphogenesis	GO:0016348	15	0.029
purine ribonucleotide catabolic process	GO:0009154	109	0.028
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.028
regulation of proteolysis	GO:0030162	87	0.028
peptidyl tyrosine phosphorylation	GO:0018108	24	0.028
peptidyl amino acid modification	GO:0018193	105	0.028
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.028
telencephalon development	GO:0021537	2	0.028
regulation of neurogenesis	GO:0050767	158	0.028
macromolecule catabolic process	GO:0009057	161	0.027
instar larval development	GO:0002168	55	0.027
compound eye photoreceptor development	GO:0042051	78	0.026
cellular response to extracellular stimulus	GO:0031668	64	0.026
zygotic determination of anterior posterior axis embryo	GO:0007354	27	0.026
humoral immune response	GO:0006959	117	0.026
negative regulation of nucleotide catabolic process	GO:0030812	1	0.026
hindbrain development	GO:0030902	2	0.026
regulation of cell migration	GO:0030334	22	0.026
ras protein signal transduction	GO:0007265	88	0.026
meiotic cell cycle	GO:0051321	171	0.026
immune response activating signal transduction	GO:0002757	2	0.026
ribonucleotide catabolic process	GO:0009261	109	0.026
convergent extension involved in gastrulation	GO:0060027	2	0.026
regulation of immune response	GO:0050776	118	0.025
regulation of cell growth	GO:0001558	43	0.025
single organism carbohydrate metabolic process	GO:0044723	72	0.024
protein import into nucleus	GO:0006606	51	0.024
glycoprotein biosynthetic process	GO:0009101	41	0.024
regulation of mapk cascade	GO:0043408	92	0.024
response to ketone	GO:1901654	34	0.024
germarium derived oocyte fate determination	GO:0007294	26	0.023
photoreceptor cell fate commitment	GO:0046552	41	0.023
regulation of stem cell differentiation	GO:2000736	14	0.023
regulation of nuclear division	GO:0051783	58	0.023
purine ribonucleoside catabolic process	GO:0046130	112	0.023
positive regulation of catalytic activity	GO:0043085	118	0.023
regulation of cell cycle	GO:0051726	291	0.023
organelle fission	GO:0048285	340	0.023
carbohydrate derivative biosynthetic process	GO:1901137	85	0.023
negative regulation of programmed cell death	GO:0043069	72	0.022
cellular response to organic cyclic compound	GO:0071407	32	0.022
positive regulation of molecular function	GO:0044093	136	0.022
salivary gland cell autophagic cell death	GO:0035071	83	0.022
cellular response to chemical stimulus	GO:0070887	199	0.022
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.022
positive regulation of receptor mediated endocytosis	GO:0048260	7	0.021
somatic stem cell maintenance	GO:0035019	14	0.021
gonad development	GO:0008406	50	0.021
cellular amine metabolic process	GO:0044106	12	0.021
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.021
renal system development	GO:0072001	72	0.021
regulation of jak stat cascade	GO:0046425	43	0.021
wing disc pattern formation	GO:0035222	66	0.020
nucleoside monophosphate metabolic process	GO:0009123	52	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
myotube cell development	GO:0014904	3	0.020
kidney epithelium development	GO:0072073	3	0.020
regulation of anatomical structure size	GO:0090066	163	0.020
regulation of catalytic activity	GO:0050790	185	0.020
regulation of mitotic cell cycle	GO:0007346	190	0.020
regulation of cellular protein metabolic process	GO:0032268	243	0.020
establishment of protein localization	GO:0045184	163	0.020
response to radiation	GO:0009314	155	0.020
regulation of mrna splicing via spliceosome	GO:0048024	64	0.020
regulation of purine nucleotide metabolic process	GO:1900542	62	0.020
positive regulation of growth	GO:0045927	75	0.020
regulation of localization	GO:0032879	275	0.020
regulation of multicellular organism growth	GO:0040014	40	0.020
ribonucleoside catabolic process	GO:0042454	112	0.019
negative regulation of neurogenesis	GO:0050768	53	0.019
endoderm formation	GO:0001706	3	0.019
spermatid differentiation	GO:0048515	114	0.019
nuclear division	GO:0000280	332	0.019
negative regulation of nervous system development	GO:0051961	92	0.019
cellular nitrogen compound catabolic process	GO:0044270	165	0.019
neural precursor cell proliferation	GO:0061351	75	0.019
organophosphate metabolic process	GO:0019637	195	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.018
embryonic foregut morphogenesis	GO:0048617	3	0.018
oocyte dorsal ventral axis specification	GO:0007310	34	0.018
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	15	0.018
purine containing compound metabolic process	GO:0072521	155	0.018
actin filament organization	GO:0007015	126	0.018
central nervous system development	GO:0007417	201	0.018
organ growth	GO:0035265	56	0.018
establishment of tissue polarity	GO:0007164	87	0.017
negative regulation of neurotransmitter secretion	GO:0046929	2	0.017

dome disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
organ system cancer	DOID:0050686	0.294
disease of cellular proliferation	DOID:14566	0.294
cancer	DOID:162	0.294
disease of anatomical entity	DOID:7	0.028
cardiovascular system disease	DOID:1287	0.022

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