IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Map60 (Dmel_CG1825)

Microtubule-associated protein 60

(Aliases: CP60,DMAP-60,Dmel\CG1825,CG1825,DMAP60,Cp60,CP-60)

Entrez: 35991
FLYBASE: FBgn0010342
UniProtKB: Q7K180

Process Predictions
Disease Predictions

Map60 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
chromosome organization	GO:0051276	360	0.760
transcription from rna polymerase ii promoter	GO:0006366	368	0.738
positive regulation of macromolecule metabolic process	GO:0010604	405	0.687
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.655
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.558
positive regulation of cellular biosynthetic process	GO:0031328	316	0.537
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.509
positive regulation of biosynthetic process	GO:0009891	316	0.467
mitotic nuclear division	GO:0007067	213	0.440
negative regulation of rna metabolic process	GO:0051253	251	0.398
regulation of cell differentiation	GO:0045595	302	0.344
chromatin organization	GO:0006325	207	0.343
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.342
dna conformation change	GO:0071103	105	0.322
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.321
intracellular signal transduction	GO:0035556	300	0.310
positive regulation of rna metabolic process	GO:0051254	271	0.302
positive regulation of rna biosynthetic process	GO:1902680	266	0.293
cell death	GO:0008219	279	0.292
positive regulation of transcription dna templated	GO:0045893	266	0.288
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.285
organelle fission	GO:0048285	340	0.272
positive regulation of gene expression	GO:0010628	290	0.253
regulation of molecular function	GO:0065009	217	0.204
positive regulation of cellular protein metabolic process	GO:0032270	118	0.175
regulation of cellular protein metabolic process	GO:0032268	243	0.168
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.166
negative regulation of transcription dna templated	GO:0045892	237	0.164
establishment of localization in cell	GO:0051649	402	0.161
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.160
regulation of programmed cell death	GO:0043067	152	0.150
intracellular transport	GO:0046907	228	0.142
regulation of protein metabolic process	GO:0051246	256	0.142
central nervous system development	GO:0007417	201	0.135
regulation of cell death	GO:0010941	173	0.134
mitotic spindle organization	GO:0007052	220	0.126
negative regulation of biosynthetic process	GO:0009890	277	0.123
regulation of phosphate metabolic process	GO:0019220	210	0.119
nuclear division	GO:0000280	332	0.118
regulation of hydrolase activity	GO:0051336	97	0.117
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.113
spindle organization	GO:0007051	253	0.109
spindle assembly	GO:0051225	80	0.107
negative regulation of gene expression	GO:0010629	387	0.106
death	GO:0016265	284	0.105
regulation of cell cycle process	GO:0010564	181	0.104
catabolic process	GO:0009056	409	0.095
regulation of cellular component biogenesis	GO:0044087	201	0.089
immune system process	GO:0002376	347	0.089
protein localization	GO:0008104	284	0.087
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.087
regulation of cellular catabolic process	GO:0031329	157	0.087
regulation of mitosis	GO:0007088	56	0.086
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.082
positive regulation of molecular function	GO:0044093	136	0.081
negative regulation of cellular metabolic process	GO:0031324	382	0.078
negative regulation of developmental process	GO:0051093	201	0.077
regulation of phosphorylation	GO:0042325	147	0.076
chromatin modification	GO:0016568	147	0.076
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.075
regulation of phosphorus metabolic process	GO:0051174	210	0.075
phosphorylation	GO:0016310	294	0.075
spindle assembly involved in mitosis	GO:0090307	50	0.074
cellular response to dna damage stimulus	GO:0006974	223	0.074
negative regulation of rna biosynthetic process	GO:1902679	240	0.074
regulation of cell cycle	GO:0051726	291	0.073
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.073
dendrite development	GO:0016358	204	0.070
negative regulation of cell differentiation	GO:0045596	143	0.070
regulation of catalytic activity	GO:0050790	185	0.070
nuclear transport	GO:0051169	72	0.069
protein modification process	GO:0036211	438	0.068
cellular catabolic process	GO:0044248	372	0.066
response to biotic stimulus	GO:0009607	294	0.066
aging	GO:0007568	143	0.065
protein dna complex assembly	GO:0065004	63	0.063
protein complex biogenesis	GO:0070271	201	0.062
ubiquitin dependent protein catabolic process	GO:0006511	78	0.060
positive regulation of phosphate metabolic process	GO:0045937	139	0.058
organic substance transport	GO:0071702	257	0.058
embryo development ending in birth or egg hatching	GO:0009792	152	0.055
covalent chromatin modification	GO:0016569	106	0.055
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.055
sister chromatid segregation	GO:0000819	92	0.055
mitotic sister chromatid segregation	GO:0000070	87	0.055
appendage morphogenesis	GO:0035107	397	0.054
positive regulation of response to stimulus	GO:0048584	323	0.054
regulation of apoptotic process	GO:0042981	130	0.053
regulation of proteolysis	GO:0030162	87	0.052
response to other organism	GO:0051707	293	0.052
proteolysis	GO:0006508	192	0.052
organonitrogen compound metabolic process	GO:1901564	318	0.051
neuroblast proliferation	GO:0007405	74	0.051
cell proliferation	GO:0008283	299	0.050
positive regulation of protein metabolic process	GO:0051247	128	0.049
g1 s transition of mitotic cell cycle	GO:0000082	31	0.049
centrosome organization	GO:0051297	163	0.049
regulation of catabolic process	GO:0009894	170	0.047
cell division	GO:0051301	248	0.047
chromosome segregation	GO:0007059	157	0.046
regulation of response to stress	GO:0080134	200	0.045
regulation of mitotic cell cycle	GO:0007346	190	0.045
intracellular protein transport	GO:0006886	104	0.045
negative regulation of response to stimulus	GO:0048585	258	0.044
response to organic substance	GO:0010033	284	0.043
regulation of multicellular organismal development	GO:2000026	414	0.042
programmed cell death	GO:0012501	257	0.042
positive regulation of phosphorus metabolic process	GO:0010562	139	0.041
mitotic sister chromatid separation	GO:0051306	30	0.041
dendrite morphogenesis	GO:0048813	199	0.041
cellularization	GO:0007349	90	0.040
mrna metabolic process	GO:0016071	124	0.040
positive regulation of signal transduction	GO:0009967	223	0.040
dna metabolic process	GO:0006259	227	0.039
stem cell differentiation	GO:0048863	117	0.039
stem cell maintenance	GO:0019827	67	0.039
ras protein signal transduction	GO:0007265	88	0.039
positive regulation of developmental process	GO:0051094	143	0.038
negative regulation of cell cycle	GO:0045786	116	0.038
mrna processing	GO:0006397	104	0.038
positive regulation of catalytic activity	GO:0043085	118	0.038
regulation of immune system process	GO:0002682	176	0.037
epithelial cell differentiation	GO:0030855	322	0.037
positive regulation of hydrolase activity	GO:0051345	78	0.037
single organism catabolic process	GO:0044712	228	0.036
protein processing	GO:0016485	68	0.036
cell cycle dna replication	GO:0044786	23	0.036
regulation of cellular localization	GO:0060341	136	0.036
regulation of cell cycle phase transition	GO:1901987	130	0.036
regulation of dna recombination	GO:0000018	4	0.035
mitotic cell cycle phase transition	GO:0044772	138	0.035
cellular protein modification process	GO:0006464	438	0.034
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.034
organic substance catabolic process	GO:1901575	308	0.034
purine containing compound catabolic process	GO:0072523	112	0.034
negative regulation of cell communication	GO:0010648	223	0.033
protein transport	GO:0015031	155	0.033
actin filament organization	GO:0007015	126	0.033
negative regulation of molecular function	GO:0044092	51	0.033
cellular protein catabolic process	GO:0044257	83	0.032
muscle organ development	GO:0007517	127	0.032
camera type eye development	GO:0043010	4	0.032
nucleobase containing small molecule metabolic process	GO:0055086	174	0.032
positive regulation of phosphorylation	GO:0042327	87	0.032
regulation of intracellular signal transduction	GO:1902531	236	0.032
positive regulation of mitotic cell cycle	GO:0045931	34	0.031
protein phosphorylation	GO:0006468	169	0.031
eye morphogenesis	GO:0048592	260	0.031
nucleoside phosphate catabolic process	GO:1901292	110	0.031
modification dependent protein catabolic process	GO:0019941	78	0.031
negative regulation of cell cycle process	GO:0010948	109	0.030
macromolecule catabolic process	GO:0009057	161	0.030
establishment or maintenance of cell polarity	GO:0007163	167	0.029
cell cycle g1 s phase transition	GO:0044843	31	0.028
negative regulation of signaling	GO:0023057	219	0.028
immune response	GO:0006955	246	0.028
open tracheal system development	GO:0007424	204	0.027
carbohydrate derivative metabolic process	GO:1901135	217	0.027
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.027
germ line stem cell maintenance	GO:0030718	50	0.027
dephosphorylation	GO:0016311	51	0.027
negative regulation of meiotic cell cycle	GO:0051447	2	0.026
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.026
cellular macromolecule localization	GO:0070727	220	0.026
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.026
regulation of protein catabolic process	GO:0042176	55	0.026
response to oxidative stress	GO:0006979	86	0.025
eye development	GO:0001654	323	0.025
negative regulation of organelle organization	GO:0010639	56	0.025
response to external biotic stimulus	GO:0043207	293	0.024
regionalization	GO:0003002	416	0.024
small molecule metabolic process	GO:0044281	305	0.024
regulation of proteasomal protein catabolic process	GO:0061136	39	0.024
positive regulation of multicellular organismal process	GO:0051240	143	0.024
macromolecular complex assembly	GO:0065003	256	0.024
positive regulation of protein modification process	GO:0031401	58	0.024
cellular response to chemical stimulus	GO:0070887	199	0.023
compound eye development	GO:0048749	307	0.023
organonitrogen compound catabolic process	GO:1901565	128	0.023
respiratory system development	GO:0060541	213	0.022
terminal button organization	GO:0072553	19	0.022
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.022
rna processing	GO:0006396	147	0.022
mitotic cytokinesis	GO:0000281	50	0.022
negative regulation of mitotic cell cycle	GO:0045930	109	0.022
camera type eye morphogenesis	GO:0048593	2	0.022
regulation of cytoplasmic transport	GO:1903649	47	0.022
negative regulation of protein processing	GO:0010955	31	0.022
protein targeting	GO:0006605	64	0.022
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.022
protein maturation	GO:0051604	71	0.022
negative regulation of cellular protein metabolic process	GO:0032269	85	0.021
single organism intracellular transport	GO:1902582	207	0.021
stem cell development	GO:0048864	79	0.021
circulatory system development	GO:0072359	82	0.021
chromosome separation	GO:0051304	42	0.020
regulation of gene expression epigenetic	GO:0040029	128	0.020
protein catabolic process	GO:0030163	101	0.020
response to abiotic stimulus	GO:0009628	341	0.020
protein complex assembly	GO:0006461	200	0.020
purine ribonucleotide metabolic process	GO:0009150	145	0.020
regulation of transport	GO:0051049	181	0.019
positive regulation of cell communication	GO:0010647	250	0.019
regulation of cellular amino acid metabolic process	GO:0006521	0	0.019
regulation of nucleocytoplasmic transport	GO:0046822	35	0.019
negative regulation of cell cycle phase transition	GO:1901988	103	0.019
nucleoside catabolic process	GO:0009164	112	0.019
retina development in camera type eye	GO:0060041	4	0.019
cell chemotaxis involved in malpighian tubule morphogenesis	GO:0061352	3	0.019
regulation of cell development	GO:0060284	215	0.019
regulation of chromosome organization	GO:0033044	64	0.019
regulation of intracellular transport	GO:0032386	64	0.019
chaeta development	GO:0022416	97	0.019
regulation of localization	GO:0032879	275	0.019
heart contraction	GO:0060047	26	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
cytokinesis	GO:0000910	90	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
negative regulation of proteolysis	GO:0045861	31	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.018
nucleotide metabolic process	GO:0009117	161	0.018
nuclear dna replication	GO:0033260	1	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.018
developmental maturation	GO:0021700	172	0.018
organelle assembly	GO:0070925	198	0.018
nuclear import	GO:0051170	51	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018
purine nucleoside catabolic process	GO:0006152	112	0.018
regulation of protein modification process	GO:0031399	112	0.018
cell migration	GO:0016477	238	0.018
positive regulation of rho protein signal transduction	GO:0035025	4	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
cystoblast division	GO:0007282	10	0.017
positive regulation of cell cycle process	GO:0090068	28	0.017
dna packaging	GO:0006323	91	0.017
cellular amine metabolic process	GO:0044106	12	0.017
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.017
cytoplasmic transport	GO:0016482	130	0.017
regulation of cell proliferation	GO:0042127	163	0.017
meiotic cell cycle process	GO:1903046	132	0.017
ribonucleoside catabolic process	GO:0042454	112	0.016
positive regulation of mitotic cell cycle phase transition	GO:1901992	20	0.016
ribonucleoside metabolic process	GO:0009119	127	0.016
neuronal stem cell division	GO:0036445	35	0.016
positive regulation of cellular component biogenesis	GO:0044089	80	0.016
carbohydrate derivative catabolic process	GO:1901136	118	0.016
regulation of organelle organization	GO:0033043	196	0.016
cellular macromolecule catabolic process	GO:0044265	136	0.016
spinal cord development	GO:0021510	1	0.016
synapse organization	GO:0050808	196	0.016
tube development	GO:0035295	244	0.016
response to endogenous stimulus	GO:0009719	119	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.016
nucleoside monophosphate metabolic process	GO:0009123	52	0.016
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.015
negative regulation of cell death	GO:0060548	81	0.015
hematopoietic or lymphoid organ development	GO:0048534	57	0.015
sensory organ morphogenesis	GO:0090596	260	0.015
stem cell proliferation	GO:0072089	88	0.015
regulation of nucleoside metabolic process	GO:0009118	50	0.015
mrna cis splicing via spliceosome	GO:0045292	1	0.015
regulation of cell shape	GO:0008360	113	0.015
positive regulation of gtpase activity	GO:0043547	43	0.015
female germ line cyst formation	GO:0048135	42	0.014
glycosyl compound metabolic process	GO:1901657	127	0.014
ribonucleotide metabolic process	GO:0009259	145	0.014
proteasomal protein catabolic process	GO:0010498	59	0.014
positive regulation of immune system process	GO:0002684	68	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
homeostatic process	GO:0042592	199	0.014
positive regulation of catabolic process	GO:0009896	105	0.014
single organism biosynthetic process	GO:0044711	206	0.014
oocyte development	GO:0048599	124	0.014
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.014
regulation of protein processing	GO:0070613	32	0.014
regulation of protein phosphorylation	GO:0001932	64	0.013
germarium derived egg chamber formation	GO:0007293	101	0.013
establishment of protein localization to organelle	GO:0072594	62	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
vesicle mediated transport	GO:0016192	381	0.013
metaphase anaphase transition of cell cycle	GO:0044784	28	0.013
organophosphate metabolic process	GO:0019637	195	0.013
regulation of anatomical structure morphogenesis	GO:0022603	242	0.013
positive regulation of neuron projection regeneration	GO:0070572	3	0.013
glycosyl compound catabolic process	GO:1901658	112	0.013
multicellular organismal aging	GO:0010259	140	0.013
regulation of multi organism process	GO:0043900	131	0.013
positive regulation of cellular component organization	GO:0051130	156	0.013
glial cell migration	GO:0008347	31	0.013
regulation of transcription by chromatin organization	GO:0034401	3	0.013
nucleocytoplasmic transport	GO:0006913	72	0.013
negative regulation of phosphate metabolic process	GO:0045936	45	0.013
tissue migration	GO:0090130	155	0.013
histone methylation	GO:0016571	40	0.013
nucleoside phosphate metabolic process	GO:0006753	162	0.013
purine nucleoside metabolic process	GO:0042278	127	0.013
ribonucleotide catabolic process	GO:0009261	109	0.013
apoptotic process	GO:0006915	159	0.012
atp catabolic process	GO:0006200	38	0.012
cellular protein localization	GO:0034613	160	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
positive regulation of organelle organization	GO:0010638	65	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
establishment of protein localization	GO:0045184	163	0.012
protein alkylation	GO:0008213	43	0.012
modification dependent macromolecule catabolic process	GO:0043632	79	0.012
rna localization	GO:0006403	115	0.012
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.012
small gtpase mediated signal transduction	GO:0007264	88	0.012
dna duplex unwinding	GO:0032508	16	0.012
histone modification	GO:0016570	106	0.012
positive regulation of intracellular transport	GO:0032388	42	0.012
embryonic organ development	GO:0048568	50	0.012
somatic stem cell division	GO:0048103	37	0.011
regulation of cell morphogenesis	GO:0022604	163	0.011
larval development	GO:0002164	104	0.011
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.011
endocytosis	GO:0006897	310	0.011
nucleosome assembly	GO:0006334	35	0.011
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
nucleoside triphosphate catabolic process	GO:0009143	108	0.011
male gamete generation	GO:0048232	201	0.011
cell cycle checkpoint	GO:0000075	95	0.011
nitrogen compound transport	GO:0071705	85	0.011
regulation of double strand break repair	GO:2000779	3	0.011
body morphogenesis	GO:0010171	2	0.011
protein localization to nucleus	GO:0034504	55	0.011
aromatic compound catabolic process	GO:0019439	166	0.011
regulation of cytoskeleton organization	GO:0051493	89	0.011
heart development	GO:0007507	82	0.011
negative regulation of phosphorylation	GO:0042326	35	0.011
wing disc morphogenesis	GO:0007472	344	0.011
single organism behavior	GO:0044708	391	0.011
oocyte differentiation	GO:0009994	145	0.011
ribose phosphate metabolic process	GO:0019693	145	0.011
negative regulation of programmed cell death	GO:0043069	72	0.011
phagocytosis	GO:0006909	215	0.011
regulation of rac gtpase activity	GO:0032314	1	0.011
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.011
maintenance of location	GO:0051235	73	0.010
positive regulation of cell cycle	GO:0045787	43	0.010
mitochondrial membrane organization	GO:0007006	3	0.010
protein import into nucleus	GO:0006606	51	0.010
single organism cellular localization	GO:1902580	180	0.010
cellular amino acid metabolic process	GO:0006520	61	0.010
ion transport	GO:0006811	145	0.010
asymmetric stem cell division	GO:0098722	49	0.010
regulation of cell division	GO:0051302	72	0.010

Map60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.033
disease of cellular proliferation	DOID:14566	0.022
organ system cancer	DOID:0050686	0.014
cancer	DOID:162	0.014

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