Drosophila melanogaster

36 known processes

cyc (Dmel_CG8727)

cycle

(Aliases: Bmal1,CG8727,CYC,dCYC,Cyc,dBma1,dbmal,dBMAL1,dBmal,dBMAL,bmal1,MOP3,BMAL1,Dmel\CG8727,bMAL1,bHLHe7,Mop3,Cycle,dbmal1,CYCLE)

cyc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rhythmic processGO:00485111060.998
circadian behaviorGO:0048512760.998
circadian rhythmGO:00076231050.987
regulation of circadian rhythmGO:0042752490.936
single organism behaviorGO:00447083910.933
rhythmic behaviorGO:0007622760.895
locomotory behaviorGO:00076261760.814
circadian sleep wake cycle sleepGO:0050802230.509
locomotor rhythmGO:0045475560.465
circadian sleep wake cycle processGO:0022410240.232
negative regulation of rna metabolic processGO:00512532510.221
Zebrafish Mouse Fly
chromatin modificationGO:00165681470.208
organelle fissionGO:00482853400.185
sleepGO:0030431490.182
protein acetylationGO:0006473390.178
negative regulation of gene expressionGO:00106293870.172
Zebrafish Mouse Fly
response to light stimulusGO:00094161240.151
Zebrafish
response to radiationGO:00093141550.149
Zebrafish
dna metabolic processGO:00062592270.140
negative regulation of transcription dna templatedGO:00458922370.138
Zebrafish Mouse Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.130
Human Mouse Fly
histone acetylationGO:0016573380.129
negative regulation of nucleobase containing compound metabolic processGO:00459342610.123
Zebrafish Mouse Fly
circadian sleep wake cycleGO:0042745280.123
peptidyl lysine acetylationGO:0018394390.123
regulation of behaviorGO:0050795750.112
transcription from rna polymerase ii promoterGO:00063663680.106
Human Mouse Fly
mitotic cell cycle phase transitionGO:00447721380.102
protein modification processGO:00362114380.102
chromatin organizationGO:00063252070.100
gene silencingGO:00164581380.098
regulation of circadian sleep wake cycle sleepGO:0045187210.097
dna integrity checkpointGO:0031570810.086
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.086
Zebrafish Mouse Fly
cell cycle checkpointGO:0000075950.076
regulation of circadian sleep wake cycleGO:0042749250.070
male gamete generationGO:00482322010.067
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.066
Human Zebrafish Mouse Rat Fly
epithelial cell differentiationGO:00308553220.063
Mouse
negative regulation of cell communicationGO:00106482230.062
Mouse
olfactory learningGO:0008355560.061
nuclear divisionGO:00002803320.060
meiotic cell cycleGO:00513211710.059
negative regulation of nitrogen compound metabolic processGO:00511722650.059
Zebrafish Mouse Fly
multi organism behaviorGO:00517051750.059
negative regulation of cellular biosynthetic processGO:00313272770.056
Zebrafish Mouse Fly
negative regulation of signal transductionGO:00099682060.056
Mouse
positive regulation of biosynthetic processGO:00098913160.055
Human Zebrafish Mouse Rat Fly
meiotic nuclear divisionGO:00071261510.053
negative regulation of cellular metabolic processGO:00313243820.052
Zebrafish Mouse Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.048
Human Zebrafish Mouse Rat Fly
response to temperature stimulusGO:00092661060.048
chromosome organizationGO:00512763600.046
cellular response to dna damage stimulusGO:00069742230.045
taxisGO:00423303040.045
peptidyl lysine modificationGO:0018205570.045
positive regulation of behaviorGO:0048520190.044
meiotic cell cycle processGO:19030461320.043
protein dna complex subunit organizationGO:0071824860.043
muscle organ developmentGO:00075171270.042
Mouse Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.042
Zebrafish Mouse Fly
cellular protein modification processGO:00064644380.038
learning or memoryGO:00076111410.038
spermatogenesisGO:00072832000.038
Mouse
negative regulation of biosynthetic processGO:00098902770.037
Zebrafish Mouse Fly
regulation of intracellular signal transductionGO:19025312360.037
Mouse
response to organophosphorusGO:004668320.037
regulation of phosphorylationGO:00423251470.037
negative regulation of macromolecule biosynthetic processGO:00105582700.035
Zebrafish Mouse Fly
positive regulation of defense responseGO:0031349590.035
regulation of mitotic cell cycleGO:00073461900.033
posttranscriptional gene silencingGO:0016441460.032
gene silencing by rnaGO:0031047570.031
response to abiotic stimulusGO:00096283410.031
Zebrafish Fly
columnar cuboidal epithelial cell developmentGO:00020662490.031
Mouse
negative regulation of rna biosynthetic processGO:19026792400.030
Zebrafish Mouse Fly
regulation of cell cycleGO:00517262910.030
Mouse
photoperiodismGO:0009648100.030
Zebrafish
developmental maturationGO:00217001720.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
Human Zebrafish Mouse Rat Fly
positive regulation of rna biosynthetic processGO:19026802660.029
Human Zebrafish Mouse Rat Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.029
Human Mouse Fly
covalent chromatin modificationGO:00165691060.028
cognitionGO:00508901410.028
determination of adult lifespanGO:00083401370.027
regulation of defense responseGO:00313471020.027
mitotic nuclear divisionGO:00070672130.026
positive regulation of rna metabolic processGO:00512542710.025
Human Zebrafish Mouse Rat Fly
internal protein amino acid acetylationGO:0006475380.025
entrainment of circadian clockGO:0009649160.024
internal peptidyl lysine acetylationGO:0018393380.024
cellular catabolic processGO:00442483720.024
Mouse
neuroblast divisionGO:0055057350.024
negative regulation of cell deathGO:0060548810.024
oocyte differentiationGO:00099941450.024
regulation of multicellular organismal developmentGO:20000264140.024
Zebrafish Mouse Fly
negative regulation of signalingGO:00230572190.024
Mouse
neurological system processGO:00508773580.023
macromolecule catabolic processGO:00090571610.023
Mouse
appendage morphogenesisGO:00351073970.022
response to nutrient levelsGO:00316671140.022
negative regulation of small gtpase mediated signal transductionGO:0051058130.022
positive regulation of transcription dna templatedGO:00458932660.022
Human Zebrafish Mouse Rat Fly
positive regulation of macromolecule metabolic processGO:00106044050.022
Human Zebrafish Mouse Rat Fly
response to bacteriumGO:00096171980.021
regulation of cellular response to stressGO:0080135890.021
Mouse
response to oxygen containing compoundGO:19017002000.021
Fly
peptidyl amino acid modificationGO:00181931050.021
adult locomotory behaviorGO:0008344760.020
regulation of epithelial cell differentiationGO:003085640.020
Mouse
regulation of gene expression epigeneticGO:00400291280.020
cell cycle phase transitionGO:00447701400.019
intracellular receptor signaling pathwayGO:0030522190.019
Mouse
learningGO:0007612750.019
regulation of cellular protein metabolic processGO:00322682430.019
peptidyl threonine phosphorylationGO:001810720.019
dna repairGO:0006281540.019
asymmetric stem cell divisionGO:0098722490.018
secretionGO:00469031090.018
Mouse
defense response to gram negative bacteriumGO:0050829940.018
cell maturationGO:00484691440.018
oocyte axis specificationGO:00073091080.017
camera type eye developmentGO:004301040.017
endocytosisGO:00068973100.017
enzyme linked receptor protein signaling pathwayGO:00071671790.017
positive regulation of gene expressionGO:00106282900.017
Human Zebrafish Mouse Rat Fly
histone modificationGO:00165701060.017
detection of external stimulusGO:0009581660.017
catabolic processGO:00090564090.017
Mouse
muscle structure developmentGO:00610612240.017
Mouse Fly
phagocytosisGO:00069092150.017
rna interferenceGO:0016246270.017
protein catabolic processGO:00301631010.016
Mouse
detection of abiotic stimulusGO:0009582660.016
positive regulation of response to stimulusGO:00485843230.016
Mouse
ubiquitin dependent protein catabolic processGO:0006511780.016
Mouse
regulation of localizationGO:00328792750.016
Mouse
multicellular organismal reproductive behaviorGO:00330571100.016
positive regulation of response to external stimulusGO:0032103440.016
modification dependent macromolecule catabolic processGO:0043632790.016
Mouse
male mating behaviorGO:0060179700.016
vesicle mediated transportGO:00161923810.016
organic substance catabolic processGO:19015753080.016
Mouse
associative learningGO:0008306650.016
modification dependent protein catabolic processGO:0019941780.015
Mouse
rna processingGO:00063961470.015
phototransductionGO:0007602520.015
negative regulation of intracellular signal transductionGO:1902532570.015
Mouse
detection of stimulusGO:00516061560.015
cellular homeostasisGO:0019725800.015
positive regulation of apoptotic signaling pathwayGO:200123540.015
nucleoside phosphate biosynthetic processGO:1901293340.015
protein complex assemblyGO:00064612000.014
negative regulation of homeostatic processGO:003284520.014
negative regulation of cell cycle processGO:00109481090.014
response to organic substanceGO:00100332840.014
Fly
immune response activating signal transductionGO:000275720.014
single organism biosynthetic processGO:00447112060.014
negative regulation of cell cycle phase transitionGO:19019881030.014
heart contractionGO:0060047260.014
rna splicing via transesterification reactionsGO:0000375730.014
ion transportGO:00068111450.013
mitotic cell cycle checkpointGO:0007093880.013
regulation of mapk cascadeGO:0043408920.013
regulation of phosphate metabolic processGO:00192202100.013
trna modificationGO:000640020.013
axon developmentGO:00615642970.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
posttranscriptional regulation of gene expressionGO:00106081450.013
cellular protein catabolic processGO:0044257830.013
Mouse
regulation of catabolic processGO:00098941700.013
Mouse
regulation of mrna metabolic processGO:1903311720.013
multicellular organismal agingGO:00102591400.013
eye developmentGO:00016543230.012
Fly
dna conformation changeGO:00711031050.012
adult behaviorGO:00305341370.012
cell deathGO:00082192790.012
multicellular organismal homeostasisGO:0048871410.012
organonitrogen compound metabolic processGO:19015643180.012
regulation of molecular functionGO:00650092170.012
response to other organismGO:00517072930.012
response to organonitrogen compoundGO:0010243750.012
Fly
memoryGO:0007613940.012
eye morphogenesisGO:00485922600.012
Fly
protein acylationGO:0043543420.012
response to lipopolysaccharideGO:003249640.012
negative regulation of developmental processGO:00510932010.012
Mouse
positive regulation of signalingGO:00230562430.012
Mouse
cellular amino acid metabolic processGO:0006520610.012
regulation of insulin secretionGO:005079650.012
Mouse
regulation of sequence specific dna binding transcription factor activityGO:0051090120.012
phosphorylationGO:00163102940.012
developmental growthGO:00485892800.012
oocyte dorsal ventral axis specificationGO:0007310340.012
regulation of cell cycle processGO:00105641810.012
cellular response to ionizing radiationGO:0071479150.012
detection of light stimulusGO:0009583580.012
regulation of catalytic activityGO:00507901850.012
regulation of response to stressGO:00801342000.012
Mouse
dopamine receptor signaling pathwayGO:000721240.012
chemotaxisGO:00069352490.012
regulation of embryonic developmentGO:0045995680.011
branching morphogenesis of an epithelial tubeGO:0048754450.011
oocyte developmentGO:00485991240.011
female meiotic divisionGO:0007143700.011
chromosome segregationGO:00070591570.011
oocyte constructionGO:00073081120.011
striated muscle myosin thick filament assemblyGO:007168830.011
mrna processingGO:00063971040.011
embryo development ending in birth or egg hatchingGO:00097921520.011
respiratory system developmentGO:00605412130.011
positive regulation of signal transductionGO:00099672230.011
Mouse
negative regulation of mitotic cell cycleGO:00459301090.011
proteolysisGO:00065081920.011
Mouse
response to ionizing radiationGO:0010212320.011
immune response regulating signaling pathwayGO:000276420.011
spermatid differentiationGO:00485151140.011
regulation of response to external stimulusGO:00321011150.011
secretion by cellGO:00329401010.011
Mouse
negative regulation of multicellular organismal processGO:00512411420.011
protein dna complex assemblyGO:0065004630.011
posttranscriptional gene silencing by rnaGO:0035194450.010
dorsal ventral pattern formationGO:00099531330.010
regulation of immune responseGO:00507761180.010
spinal cord developmentGO:002151010.010
small gtpase mediated signal transductionGO:0007264880.010
regulation of heart contractionGO:0008016210.010
regulation of phosphorus metabolic processGO:00511742100.010
cellular response to chemical stimulusGO:00708871990.010
Mouse Fly

cyc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.019