IMP: Integrative Multi-species Prediction

Drosophila melanogaster

27 known processes

Gcn2 (Dmel_CG1609)

CG1609 gene product from transcript CG1609-RA

(Aliases: EIF2,dGCN2,CG1609,GCN2,Dmel\CG1609,DGCN2)

Entrez: 43709
FLYBASE: FBgn0019990
UniProtKB: Q9V9X8

Process Predictions
Disease Predictions

Gcn2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
defense response to bacterium	GO:0042742	178	0.292
immune system process	GO:0002376	347	0.220
protein modification process	GO:0036211	438	0.202
regionalization	GO:0003002	416	0.186
positive regulation of macromolecule metabolic process	GO:0010604	405	0.180
response to biotic stimulus	GO:0009607	294	0.177
negative regulation of gene expression	GO:0010629	387	0.167	Mouse
intracellular signal transduction	GO:0035556	300	0.156
response to external biotic stimulus	GO:0043207	293	0.155
cuticle development	GO:0042335	86	0.146
regulation of catabolic process	GO:0009894	170	0.145
negative regulation of cellular metabolic process	GO:0031324	382	0.142	Mouse
positive regulation of protein metabolic process	GO:0051247	128	0.132
transcription from rna polymerase ii promoter	GO:0006366	368	0.128
catabolic process	GO:0009056	409	0.123
defense response	GO:0006952	300	0.121
response to other organism	GO:0051707	293	0.119
chromosome organization	GO:0051276	360	0.112
organonitrogen compound metabolic process	GO:1901564	318	0.107	Yeast
cell proliferation	GO:0008283	299	0.104
cellular protein modification process	GO:0006464	438	0.099
innate immune response	GO:0045087	144	0.099
regulation of cell cycle process	GO:0010564	181	0.098
positive regulation of catabolic process	GO:0009896	105	0.098
response to abiotic stimulus	GO:0009628	341	0.093
response to bacterium	GO:0009617	198	0.091
regulation of chitin based cuticle tanning	GO:0007564	14	0.088
negative regulation of signal transduction	GO:0009968	206	0.087
negative regulation of response to stimulus	GO:0048585	258	0.086
regulation of molecular function	GO:0065009	217	0.085
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.083
positive regulation of biosynthetic process	GO:0009891	316	0.082
organic substance catabolic process	GO:1901575	308	0.082
cellular catabolic process	GO:0044248	372	0.081
dorsal ventral pattern formation	GO:0009953	133	0.080
pigmentation	GO:0043473	75	0.079
trna aminoacylation	GO:0043039	2	0.078
purine containing compound catabolic process	GO:0072523	112	0.078
vesicle mediated transport	GO:0016192	381	0.078
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.078
posttranscriptional regulation of gene expression	GO:0010608	145	0.075	Yeast Mouse
proteolysis	GO:0006508	192	0.073
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.073
phagocytosis	GO:0006909	215	0.073
regulation of intracellular signal transduction	GO:1902531	236	0.072
regulation of catalytic activity	GO:0050790	185	0.072
negative regulation of biosynthetic process	GO:0009890	277	0.071	Mouse
regulation of hydrolase activity	GO:0051336	97	0.071
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.069
molting cycle chitin based cuticle	GO:0007591	56	0.068
localization of cell	GO:0051674	257	0.066
positive regulation of hydrolase activity	GO:0051345	78	0.063
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.063
lateral inhibition	GO:0046331	206	0.062
response to organic substance	GO:0010033	284	0.062	Mouse
molting cycle	GO:0042303	56	0.061
chromatin assembly or disassembly	GO:0006333	52	0.061
positive regulation of molecular function	GO:0044093	136	0.061
regulation of protein metabolic process	GO:0051246	256	0.061	Yeast Mouse
mapk cascade	GO:0000165	107	0.060
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.060
regulation of transport	GO:0051049	181	0.060
regulation of phosphate metabolic process	GO:0019220	210	0.059
negative regulation of developmental process	GO:0051093	201	0.058
ribonucleotide catabolic process	GO:0009261	109	0.058
regulation of ras protein signal transduction	GO:0046578	93	0.058
regulation of cell cycle	GO:0051726	291	0.056
positive regulation of phosphate metabolic process	GO:0045937	139	0.056
positive regulation of cellular catabolic process	GO:0031331	95	0.055
dna damage checkpoint	GO:0000077	78	0.055	Yeast
regulation of phosphorus metabolic process	GO:0051174	210	0.055
response to lipopolysaccharide	GO:0032496	4	0.055
organelle fission	GO:0048285	340	0.055
phosphorylation	GO:0016310	294	0.054
negative regulation of cellular biosynthetic process	GO:0031327	277	0.054	Mouse
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.054	Mouse
positive regulation of catalytic activity	GO:0043085	118	0.053
macromolecule catabolic process	GO:0009057	161	0.053
regulation of mitotic cell cycle	GO:0007346	190	0.052
male gamete generation	GO:0048232	201	0.052
organic acid metabolic process	GO:0006082	103	0.051	Yeast
ribonucleoside catabolic process	GO:0042454	112	0.051
regulation of defense response to virus by host	GO:0050691	10	0.051
negative regulation of kinase activity	GO:0033673	16	0.050
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.049
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.049	Mouse
appendage morphogenesis	GO:0035107	397	0.048
regulation of localization	GO:0032879	275	0.047
negative regulation of multicellular organismal process	GO:0051241	142	0.047
imaginal disc derived appendage development	GO:0048737	399	0.047
cell death	GO:0008219	279	0.047
purine ribonucleotide catabolic process	GO:0009154	109	0.047
positive regulation of cell communication	GO:0010647	250	0.047
immune response	GO:0006955	246	0.046
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.046
regulation of mapk cascade	GO:0043408	92	0.046
organic cyclic compound catabolic process	GO:1901361	168	0.046
endocytosis	GO:0006897	310	0.045
dna integrity checkpoint	GO:0031570	81	0.045	Yeast
protein import	GO:0017038	55	0.045
appendage development	GO:0048736	401	0.044
response to oxidative stress	GO:0006979	86	0.044
protein phosphorylation	GO:0006468	169	0.043
positive regulation of immune response	GO:0050778	63	0.043
cell fate determination	GO:0001709	91	0.043
regulation of cell differentiation	GO:0045595	302	0.042
camera type eye development	GO:0043010	4	0.042
heterochromatin organization	GO:0070828	25	0.041
connective tissue development	GO:0061448	3	0.041
establishment of localization in cell	GO:0051649	402	0.041
ras protein signal transduction	GO:0007265	88	0.041
heterocycle catabolic process	GO:0046700	166	0.041
positive regulation of cellular protein metabolic process	GO:0032270	118	0.040
gene silencing by rna	GO:0031047	57	0.039
death	GO:0016265	284	0.039
chromatin modification	GO:0016568	147	0.039
single organism nuclear import	GO:1902593	51	0.038
wing disc morphogenesis	GO:0007472	344	0.038
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO:0070059	4	0.037
negative regulation of rna biosynthetic process	GO:1902679	240	0.037
regulation of cellular catabolic process	GO:0031329	157	0.037
developmental pigmentation	GO:0048066	68	0.037
negative regulation of signaling	GO:0023057	219	0.037
regulation of gene expression epigenetic	GO:0040029	128	0.036
growth	GO:0040007	359	0.036
ion transport	GO:0006811	145	0.036
programmed cell death	GO:0012501	257	0.035
covalent chromatin modification	GO:0016569	106	0.035
membrane fusion	GO:0061025	42	0.035
positive regulation of gene expression	GO:0010628	290	0.035
gene silencing	GO:0016458	138	0.035
positive regulation of cellular biosynthetic process	GO:0031328	316	0.035
regulation of cytoplasmic transport	GO:1903649	47	0.034
posttranscriptional gene silencing by rna	GO:0035194	45	0.034
defense response to other organism	GO:0098542	225	0.034
regulation of nucleocytoplasmic transport	GO:0046822	35	0.034
trna aminoacylation for protein translation	GO:0006418	2	0.034
necrotic cell death	GO:0070265	1	0.034
positive regulation of defense response	GO:0031349	59	0.033
single organism biosynthetic process	GO:0044711	206	0.033	Yeast
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.033
positive regulation of response to stimulus	GO:0048584	323	0.033
nucleoside triphosphate metabolic process	GO:0009141	120	0.032
positive regulation of defense response to virus by host	GO:0002230	10	0.032
small molecule metabolic process	GO:0044281	305	0.032	Yeast
positive regulation of signaling	GO:0023056	243	0.032
purine nucleoside catabolic process	GO:0006152	112	0.032
small gtpase mediated signal transduction	GO:0007264	88	0.032
adult chitin containing cuticle pigmentation	GO:0048085	16	0.031
positive regulation of jun kinase activity	GO:0043507	4	0.031
nucleobase containing small molecule metabolic process	GO:0055086	174	0.031
regulation of organelle organization	GO:0033043	196	0.030
regulation of cellular protein metabolic process	GO:0032268	243	0.030	Yeast Mouse
regulation of nuclear division	GO:0051783	58	0.030
regulation of developmental pigmentation	GO:0048070	24	0.029
cellular response to abiotic stimulus	GO:0071214	58	0.029
protein catabolic process	GO:0030163	101	0.029
positive regulation of proteolysis	GO:0045862	52	0.029
single organism membrane fusion	GO:0044801	42	0.029
regulation of developmental growth	GO:0048638	174	0.029
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.028
central nervous system development	GO:0007417	201	0.028
mucosal immune response	GO:0002385	10	0.028
spindle assembly	GO:0051225	80	0.028
positive regulation of intracellular signal transduction	GO:1902533	116	0.028
antimicrobial humoral response	GO:0019730	99	0.028
regulation of growth	GO:0040008	233	0.028
cellular amino acid metabolic process	GO:0006520	61	0.027	Yeast
glycosyl compound catabolic process	GO:1901658	112	0.027
cellular response to chemical stimulus	GO:0070887	199	0.027	Mouse
regulation of establishment of protein localization	GO:0070201	61	0.027
immune response regulating signaling pathway	GO:0002764	2	0.027
spermatogenesis	GO:0007283	200	0.027
dna repair	GO:0006281	54	0.027
nuclear division	GO:0000280	332	0.026
epithelial cell differentiation	GO:0030855	322	0.026
defense response to gram negative bacterium	GO:0050829	94	0.026
regulation of proteolysis	GO:0030162	87	0.026
positive regulation of peptidase activity	GO:0010952	29	0.026
glycosyl compound metabolic process	GO:1901657	127	0.026
regulation of defense response	GO:0031347	102	0.026
organelle assembly	GO:0070925	198	0.026
carbohydrate metabolic process	GO:0005975	82	0.025
mitotic dna integrity checkpoint	GO:0044774	75	0.025
imaginal disc derived wing morphogenesis	GO:0007476	337	0.025
cellular response to organic substance	GO:0071310	132	0.025	Mouse
positive regulation of transcription dna templated	GO:0045893	266	0.025
regulation of protein transport	GO:0051223	57	0.025
regulation of multicellular organismal development	GO:2000026	414	0.025
regulation of map kinase activity	GO:0043405	17	0.025
cellular nitrogen compound catabolic process	GO:0044270	165	0.025
regulation of intracellular transport	GO:0032386	64	0.024
positive regulation of mapk cascade	GO:0043410	63	0.024
mitotic nuclear division	GO:0007067	213	0.024
humoral immune response	GO:0006959	117	0.024
intracellular transport	GO:0046907	228	0.024
negative regulation of transcription dna templated	GO:0045892	237	0.024
single organism catabolic process	GO:0044712	228	0.024
protein transport	GO:0015031	155	0.023
positive regulation of rna metabolic process	GO:0051254	271	0.023
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.023
purine ribonucleoside catabolic process	GO:0046130	112	0.023
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.023
anatomical structure homeostasis	GO:0060249	97	0.023
chromatin organization	GO:0006325	207	0.023
dna metabolic process	GO:0006259	227	0.023
protein localization to nucleus	GO:0034504	55	0.023
regulation of innate immune response	GO:0045088	71	0.023
macromolecular complex assembly	GO:0065003	256	0.023
carbohydrate derivative catabolic process	GO:1901136	118	0.023
imaginal disc pattern formation	GO:0007447	91	0.023
negative regulation of cell cycle phase transition	GO:1901988	103	0.023
protein complex biogenesis	GO:0070271	201	0.023
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.023
regulation of adult chitin containing cuticle pigmentation	GO:0048082	13	0.023
carbohydrate derivative metabolic process	GO:1901135	217	0.023
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022
nucleoside catabolic process	GO:0009164	112	0.022
membrane organization	GO:0061024	112	0.022
positive regulation of transport	GO:0051050	92	0.022
regulation of jun kinase activity	GO:0043506	8	0.022
establishment of protein localization	GO:0045184	163	0.022
jak stat cascade	GO:0007259	49	0.022
regulation of mitosis	GO:0007088	56	0.021
response to starvation	GO:0042594	97	0.021	Mouse
organophosphate metabolic process	GO:0019637	195	0.021
posttranscriptional gene silencing	GO:0016441	46	0.021
heart development	GO:0007507	82	0.021
negative regulation of cell communication	GO:0010648	223	0.021
regulation of multi organism process	GO:0043900	131	0.021
negative regulation of rna metabolic process	GO:0051253	251	0.021
nucleotide catabolic process	GO:0009166	109	0.021
protein targeting to nucleus	GO:0044744	51	0.021
positive regulation of signal transduction	GO:0009967	223	0.021
regulation of intracellular protein transport	GO:0033157	46	0.021
regulation of response to stress	GO:0080134	200	0.021
regulation of cell cycle phase transition	GO:1901987	130	0.020
post embryonic appendage morphogenesis	GO:0035120	385	0.020
response to light stimulus	GO:0009416	124	0.020
regulation of dna metabolic process	GO:0051052	34	0.020
mrna metabolic process	GO:0016071	124	0.020
protein targeting	GO:0006605	64	0.020
regulation of protein modification process	GO:0031399	112	0.020
eye development	GO:0001654	323	0.020
aromatic compound catabolic process	GO:0019439	166	0.020
skin development	GO:0043588	65	0.020
positive regulation of protein transport	GO:0051222	37	0.020
ribonucleotide metabolic process	GO:0009259	145	0.019
cellular response to dsrna	GO:0071359	15	0.019
protein modification by small protein conjugation	GO:0032446	79	0.019
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.019
homeostatic process	GO:0042592	199	0.019
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.019
nucleoside phosphate catabolic process	GO:1901292	110	0.019
regulation of cell development	GO:0060284	215	0.019
aging	GO:0007568	143	0.019	Yeast
single organism carbohydrate metabolic process	GO:0044723	72	0.019
sensory organ morphogenesis	GO:0090596	260	0.018
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.018
response to organic cyclic compound	GO:0014070	89	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.018
atp catabolic process	GO:0006200	38	0.018
nucleoside metabolic process	GO:0009116	127	0.018
organonitrogen compound catabolic process	GO:1901565	128	0.017
response to organophosphorus	GO:0046683	2	0.017
purine ribonucleotide metabolic process	GO:0009150	145	0.017
telencephalon development	GO:0021537	2	0.017
regulation of immune system process	GO:0002682	176	0.017
protein import into nucleus	GO:0006606	51	0.017
nucleoside triphosphate catabolic process	GO:0009143	108	0.017
nucleotide metabolic process	GO:0009117	161	0.017
positive regulation of nucleoside metabolic process	GO:0045979	47	0.017
negative regulation of nervous system development	GO:0051961	92	0.017
regulation of cellular localization	GO:0060341	136	0.017
response to radiation	GO:0009314	155	0.017
cation transmembrane transport	GO:0098655	88	0.017
chitin based cuticle sclerotization	GO:0007593	19	0.017
cell division	GO:0051301	248	0.017
detection of stimulus	GO:0051606	156	0.017
positive regulation of cell death	GO:0010942	69	0.017
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016	Mouse
cellular response to unfolded protein	GO:0034620	9	0.016	Mouse
cellular macromolecule catabolic process	GO:0044265	136	0.016
cellular hyperosmotic salinity response	GO:0071475	1	0.016
response to copper ion	GO:0046688	4	0.016
regulation of cuticle pigmentation	GO:0048079	16	0.016
germ line stem cell maintenance	GO:0030718	50	0.016
regulation of protein catabolic process	GO:0042176	55	0.016
ensheathment of neurons	GO:0007272	10	0.016
cation homeostasis	GO:0055080	51	0.016
negative regulation of growth	GO:0045926	84	0.016
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.016
response to temperature stimulus	GO:0009266	106	0.016
positive regulation of cellular component biogenesis	GO:0044089	80	0.016
purine nucleotide catabolic process	GO:0006195	109	0.016
regulation of purine nucleotide catabolic process	GO:0033121	48	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.016
organophosphate catabolic process	GO:0046434	112	0.015
regulation of response to external stimulus	GO:0032101	115	0.015
cellular response to biotic stimulus	GO:0071216	4	0.015
negative regulation of epidermal growth factor receptor signaling pathway	GO:0042059	29	0.015
cell migration	GO:0016477	238	0.015
negative regulation of developmental growth	GO:0048640	64	0.015
regulation of programmed cell death	GO:0043067	152	0.015
skeletal muscle fiber development	GO:0048741	3	0.015
antennal development	GO:0007469	25	0.015
autophagy	GO:0006914	108	0.015
response to alcohol	GO:0097305	95	0.015
regulation of membrane potential	GO:0042391	35	0.015
regulation of protein import into nucleus	GO:0042306	28	0.015
ribonucleoside metabolic process	GO:0009119	127	0.015
organ or tissue specific immune response	GO:0002251	10	0.015
hair cell differentiation	GO:0035315	47	0.014
response to endoplasmic reticulum stress	GO:0034976	28	0.014	Mouse
organic substance transport	GO:0071702	257	0.014
defense response to gram positive bacterium	GO:0050830	41	0.014
limb development	GO:0060173	1	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
antimicrobial peptide production	GO:0002775	46	0.014
immune response activating signal transduction	GO:0002757	2	0.014
oxoacid metabolic process	GO:0043436	103	0.014	Yeast
spindle organization	GO:0007051	253	0.014
forebrain development	GO:0030900	2	0.014
rna processing	GO:0006396	147	0.014
cellular response to dna damage stimulus	GO:0006974	223	0.014	Yeast
stem cell maintenance	GO:0019827	67	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.014
regulation of sequestering of calcium ion	GO:0051282	3	0.014
regulation of cellular component biogenesis	GO:0044087	201	0.013
neuronal action potential	GO:0019228	10	0.013
regulation of nucleotide metabolic process	GO:0006140	62	0.013
axon ensheathment	GO:0008366	10	0.013
positive regulation of phosphorylation	GO:0042327	87	0.013
negative regulation of cell cycle process	GO:0010948	109	0.013
carboxylic acid metabolic process	GO:0019752	92	0.013	Yeast
hindbrain development	GO:0030902	2	0.013
epithelial cell development	GO:0002064	274	0.013
amino acid activation	GO:0043038	3	0.013
response to nitrogen compound	GO:1901698	90	0.013
response to decreased oxygen levels	GO:0036293	58	0.013
wnt signaling pathway	GO:0016055	98	0.013
body morphogenesis	GO:0010171	2	0.012
regulation of nucleoside metabolic process	GO:0009118	50	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
glycoprotein metabolic process	GO:0009100	41	0.012
regulation of immune response	GO:0050776	118	0.012
protein localization	GO:0008104	284	0.012
regulation of apoptotic process	GO:0042981	130	0.012
cytoplasmic translation	GO:0002181	0	0.012
nuclear transport	GO:0051169	72	0.012
regulation of response to oxidative stress	GO:1902882	4	0.012
purine containing compound metabolic process	GO:0072521	155	0.012
positive regulation of ras gtpase activity	GO:0032320	36	0.012
gastrulation with mouth forming first	GO:0001703	36	0.012
regulation of mrna metabolic process	GO:1903311	72	0.012
dna conformation change	GO:0071103	105	0.012
regulation of protein phosphorylation	GO:0001932	64	0.012
cellular macromolecular complex assembly	GO:0034622	153	0.012
taxis	GO:0042330	304	0.012
regulation of phosphorylation	GO:0042325	147	0.012
nucleoside monophosphate catabolic process	GO:0009125	39	0.012
inositol lipid mediated signaling	GO:0048017	4	0.012
endosomal transport	GO:0016197	44	0.012
response to hexose	GO:0009746	3	0.012
single organism intracellular transport	GO:1902582	207	0.012
purine nucleoside metabolic process	GO:0042278	127	0.011
regulation of protein localization	GO:0032880	76	0.011
immune effector process	GO:0002252	98	0.011
apoptotic process	GO:0006915	159	0.011
purine nucleotide metabolic process	GO:0006163	146	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.011
nucleocytoplasmic transport	GO:0006913	72	0.011
response to topologically incorrect protein	GO:0035966	10	0.011	Mouse
cation transport	GO:0006812	110	0.011
regulation of epithelial cell differentiation	GO:0030856	4	0.011
positive regulation of exocytosis	GO:0045921	4	0.011
i kappab phosphorylation	GO:0007252	3	0.011
production of small rna involved in gene silencing by rna	GO:0070918	15	0.011
regulation of cellular component size	GO:0032535	98	0.011
positive regulation of reactive oxygen species metabolic process	GO:2000379	0	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
regulation of gtpase activity	GO:0043087	44	0.011
single organism membrane organization	GO:0044802	93	0.010
cellular homeostasis	GO:0019725	80	0.010
regulation of gtp catabolic process	GO:0033124	44	0.010
response to organonitrogen compound	GO:0010243	75	0.010
regulation of rab gtpase activity	GO:0032313	7	0.010
ribose phosphate metabolic process	GO:0019693	145	0.010
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.010
extrinsic apoptotic signaling pathway	GO:0097191	1	0.010
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.010
negative regulation of homeostatic process	GO:0032845	2	0.010
cellular response to lipopolysaccharide	GO:0071222	3	0.010
detection of stimulus involved in sensory perception	GO:0050906	92	0.010
positive regulation of ion transmembrane transporter activity	GO:0032414	4	0.010
guanosine containing compound catabolic process	GO:1901069	74	0.010
eye antennal disc development	GO:0035214	60	0.010
xenobiotic transport	GO:0042908	1	0.010

Gcn2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.053
disease of metabolism	DOID:0014667	0.019
nervous system disease	DOID:863	0.018
disease of cellular proliferation	DOID:14566	0.017
cancer	DOID:162	0.017
organ system cancer	DOID:0050686	0.017
inherited metabolic disorder	DOID:655	0.015
central nervous system disease	DOID:331	0.013

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