IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

sec63 (Dmel_CG8583)

CG8583 gene product from transcript CG8583-RA

(Aliases: Dmel\CG8583,peg,anon-WO0118547.333,CG8583)

Entrez: 38819
FLYBASE: FBgn0035771
UniProtKB: Q9VS57

Process Predictions
Disease Predictions

sec63 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
establishment of localization in cell	GO:0051649	402	0.119	Human Mouse
secretion	GO:0046903	109	0.107
carbohydrate derivative metabolic process	GO:1901135	217	0.085
oligosaccharide biosynthetic process	GO:0009312	10	0.071
protein localization	GO:0008104	284	0.063	Human Mouse
organic substance transport	GO:0071702	257	0.063	Human Mouse
secretory granule organization	GO:0033363	6	0.052
o glycan processing	GO:0016266	3	0.050
catabolic process	GO:0009056	409	0.048
endomembrane system organization	GO:0010256	119	0.048
respiratory system development	GO:0060541	213	0.047
vesicle organization	GO:0016050	44	0.045
vesicle mediated transport	GO:0016192	381	0.043
single organism catabolic process	GO:0044712	228	0.042
modification dependent protein catabolic process	GO:0019941	78	0.041
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.038
defense response to bacterium	GO:0042742	178	0.038
positive regulation of secretion	GO:0051047	22	0.035
organic substance catabolic process	GO:1901575	308	0.035
positive regulation of rna biosynthetic process	GO:1902680	266	0.034
camera type eye development	GO:0043010	4	0.034
death	GO:0016265	284	0.033
response to other organism	GO:0051707	293	0.033
organonitrogen compound metabolic process	GO:1901564	318	0.032
response to biotic stimulus	GO:0009607	294	0.032
protein transport	GO:0015031	155	0.032	Human Mouse
secretion by cell	GO:0032940	101	0.032
cellular catabolic process	GO:0044248	372	0.031
purine containing compound metabolic process	GO:0072521	155	0.031
small molecule metabolic process	GO:0044281	305	0.031
regulation of response to stress	GO:0080134	200	0.031
regulation of localization	GO:0032879	275	0.030
defense response	GO:0006952	300	0.030
positive regulation of transcription dna templated	GO:0045893	266	0.030
positive regulation of macromolecule metabolic process	GO:0010604	405	0.029
heterocycle catabolic process	GO:0046700	166	0.028
protein catabolic process	GO:0030163	101	0.028
purine nucleoside metabolic process	GO:0042278	127	0.027
cell death	GO:0008219	279	0.026
body morphogenesis	GO:0010171	2	0.026
single organism biosynthetic process	GO:0044711	206	0.026
nucleobase containing compound catabolic process	GO:0034655	165	0.026
regulation of transport	GO:0051049	181	0.026
ribonucleoside metabolic process	GO:0009119	127	0.026
positive regulation of rna metabolic process	GO:0051254	271	0.026
response to external biotic stimulus	GO:0043207	293	0.025
tube morphogenesis	GO:0035239	191	0.025
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.025
open tracheal system development	GO:0007424	204	0.025
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.024
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.024
purine ribonucleotide catabolic process	GO:0009154	109	0.024
regionalization	GO:0003002	416	0.023
purine nucleotide metabolic process	GO:0006163	146	0.023
purine nucleotide catabolic process	GO:0006195	109	0.023
single organism carbohydrate metabolic process	GO:0044723	72	0.023
endocytosis	GO:0006897	310	0.022
phagocytosis	GO:0006909	215	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.022
nucleobase containing small molecule metabolic process	GO:0055086	174	0.022
dendrite development	GO:0016358	204	0.022
purine ribonucleotide metabolic process	GO:0009150	145	0.022
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.021
ribonucleotide metabolic process	GO:0009259	145	0.021
ribose phosphate metabolic process	GO:0019693	145	0.021
purine ribonucleoside metabolic process	GO:0046128	127	0.021
positive regulation of cellular biosynthetic process	GO:0031328	316	0.021
ribonucleoside catabolic process	GO:0042454	112	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.020
lipid localization	GO:0010876	54	0.019
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.019
cellular protein localization	GO:0034613	160	0.019	Human Mouse
oxoacid metabolic process	GO:0043436	103	0.019
cellular protein modification process	GO:0006464	438	0.019
single organism behavior	GO:0044708	391	0.019
membrane organization	GO:0061024	112	0.018	Human Mouse
homeostatic process	GO:0042592	199	0.018
nucleotide metabolic process	GO:0009117	161	0.018
ribonucleotide catabolic process	GO:0009261	109	0.018
golgi vesicle transport	GO:0048193	27	0.018
nucleoside catabolic process	GO:0009164	112	0.018
response to bacterium	GO:0009617	198	0.018
nucleoside triphosphate metabolic process	GO:0009141	120	0.017
regulation of secretion	GO:0051046	44	0.017
organic acid metabolic process	GO:0006082	103	0.017
purine nucleoside catabolic process	GO:0006152	112	0.017
cellular nitrogen compound catabolic process	GO:0044270	165	0.017
single organism intracellular transport	GO:1902582	207	0.017	Human Mouse
vesicle targeting to from or within golgi	GO:0048199	1	0.017
embryo development ending in birth or egg hatching	GO:0009792	152	0.016
purine containing compound catabolic process	GO:0072523	112	0.016
tube development	GO:0035295	244	0.016
immune system process	GO:0002376	347	0.016
nucleoside triphosphate catabolic process	GO:0009143	108	0.016
establishment of protein localization	GO:0045184	163	0.016	Human Mouse
positive regulation of response to stimulus	GO:0048584	323	0.016
organic cyclic compound catabolic process	GO:1901361	168	0.016
proteasomal protein catabolic process	GO:0010498	59	0.016
organophosphate metabolic process	GO:0019637	195	0.016
defense response to other organism	GO:0098542	225	0.015
immune response	GO:0006955	246	0.015
nucleoside phosphate catabolic process	GO:1901292	110	0.015
nucleoside metabolic process	GO:0009116	127	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.015
nucleotide catabolic process	GO:0009166	109	0.015
positive regulation of transport	GO:0051050	92	0.015
maintenance of location	GO:0051235	73	0.015
carboxylic acid metabolic process	GO:0019752	92	0.015
dendrite morphogenesis	GO:0048813	199	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
programmed cell death	GO:0012501	257	0.015
lipid storage	GO:0019915	38	0.015
regulation of immune response	GO:0050776	118	0.014
autophagy	GO:0006914	108	0.014
macromolecule catabolic process	GO:0009057	161	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
forebrain development	GO:0030900	2	0.014
aromatic compound catabolic process	GO:0019439	166	0.014
spermatogenesis	GO:0007283	200	0.014
ion transport	GO:0006811	145	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.014
response to hexose	GO:0009746	3	0.014
purine ribonucleoside catabolic process	GO:0046130	112	0.013
single organism membrane organization	GO:0044802	93	0.013	Human Mouse
modification dependent macromolecule catabolic process	GO:0043632	79	0.013
intracellular protein transport	GO:0006886	104	0.013	Human Mouse
organophosphate catabolic process	GO:0046434	112	0.013
cellular macromolecule localization	GO:0070727	220	0.013	Human Mouse
golgi organization	GO:0007030	66	0.013
digestive tract development	GO:0048565	149	0.013
glycosyl compound metabolic process	GO:1901657	127	0.013
tricarboxylic acid metabolic process	GO:0072350	1	0.013
positive regulation of gene expression	GO:0010628	290	0.013
glycosyl compound catabolic process	GO:1901658	112	0.013
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.012
carbohydrate derivative biosynthetic process	GO:1901137	85	0.012
cytoplasmic transport	GO:0016482	130	0.012	Human Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.012
synaptic transmission	GO:0007268	288	0.012
adult behavior	GO:0030534	137	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
regulation of multi organism process	GO:0043900	131	0.012
positive regulation of catabolic process	GO:0009896	105	0.012
regulation of cellular catabolic process	GO:0031329	157	0.012
protein glycosylation	GO:0006486	32	0.012
chromosome separation	GO:0051304	42	0.012
proteolysis	GO:0006508	192	0.012
secondary metabolite biosynthetic process	GO:0044550	24	0.012
intracellular transport	GO:0046907	228	0.011	Human Mouse
nucleoside phosphate metabolic process	GO:0006753	162	0.011
positive regulation of cellular component organization	GO:0051130	156	0.011
digestive system development	GO:0055123	149	0.011
defense response to gram negative bacterium	GO:0050829	94	0.011
regulation of immune system process	GO:0002682	176	0.011
response to unfolded protein	GO:0006986	9	0.011
regulation of innate immune response	GO:0045088	71	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
protein transmembrane transport	GO:0071806	4	0.011
ubiquitin dependent protein catabolic process	GO:0006511	78	0.011
nuclear division	GO:0000280	332	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
regulation of catabolic process	GO:0009894	170	0.011
compound eye development	GO:0048749	307	0.011
male gamete generation	GO:0048232	201	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
protein complex biogenesis	GO:0070271	201	0.011
extracellular matrix organization	GO:0030198	32	0.010
regulation of defense response	GO:0031347	102	0.010
negative regulation of gene expression	GO:0010629	387	0.010
regulation of anatomical structure size	GO:0090066	163	0.010
negative regulation of cellular metabolic process	GO:0031324	382	0.010
positive regulation of cellular catabolic process	GO:0031331	95	0.010
carbohydrate metabolic process	GO:0005975	82	0.010
digestive tract morphogenesis	GO:0048546	127	0.010
apoptotic process	GO:0006915	159	0.010

sec63 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.026
nervous system disease	DOID:863	0.014
disease of metabolism	DOID:0014667	0.011
urinary system disease	DOID:18	0.011

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