Drosophila melanogaster

0 known processes

Spn42Db (Dmel_CG9454)

Serpin 42Db

(Aliases: Dmel\CG9454,CG9454)

Spn42Db biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523000.061
Rat Fly
response to biotic stimulusGO:00096072940.061
Fly
defense response to other organismGO:00985422250.058
Fly
response to other organismGO:00517072930.057
Fly
response to external biotic stimulusGO:00432072930.055
Fly
immune system processGO:00023763470.052
Fly
defense response to bacteriumGO:00427421780.047
Fly
response to bacteriumGO:00096171980.042
Fly
organonitrogen compound metabolic processGO:19015643180.041
Fly
catabolic processGO:00090564090.036
organelle fissionGO:00482853400.035
nuclear divisionGO:00002803320.035
endocytosisGO:00068973100.034
positive regulation of response to stimulusGO:00485843230.033
cell cell signaling involved in cell fate commitmentGO:00451682100.033
immune responseGO:00069552460.032
Fly
vesicle mediated transportGO:00161923810.032
small molecule metabolic processGO:00442813050.032
organic substance transportGO:00717022570.031
regulation of immune system processGO:00026821760.031
Fly
taxisGO:00423303040.030
response to abiotic stimulusGO:00096283410.030
organic substance catabolic processGO:19015753080.030
sterol homeostasisGO:005509240.029
appendage morphogenesisGO:00351073970.029
imaginal disc derived appendage morphogenesisGO:00351143950.029
cellular catabolic processGO:00442483720.028
appendage developmentGO:00487364010.028
response to lipopolysaccharideGO:003249640.028
positive regulation of signalingGO:00230562430.028
cellular protein modification processGO:00064644380.027
establishment of localization in cellGO:00516494020.027
response to organic substanceGO:00100332840.027
protein modification processGO:00362114380.027
negative regulation of gene expressionGO:00106293870.027
Rat Fly
developmental growthGO:00485892800.027
Rat
single organism behaviorGO:00447083910.026
organic acid metabolic processGO:00060821030.026
sensory perception of chemical stimulusGO:00076061160.026
wing disc morphogenesisGO:00074723440.026
oxoacid metabolic processGO:00434361030.026
body morphogenesisGO:001017120.026
neurological system processGO:00508773580.025
positive regulation of cell communicationGO:00106472500.025
regulation of localizationGO:00328792750.025
phagocytosisGO:00069092150.025
homeostatic processGO:00425921990.024
forebrain developmentGO:003090020.024
cell proliferationGO:00082832990.024
imaginal disc derived wing morphogenesisGO:00074763370.024
growthGO:00400073590.024
Rat
positive regulation of signal transductionGO:00099672230.024
intracellular transportGO:00469072280.024
response to oxygen containing compoundGO:19017002000.023
chromosome organizationGO:00512763600.023
protein localizationGO:00081042840.023
regulation of cellular amine metabolic processGO:003323830.023
imaginal disc derived appendage developmentGO:00487373990.023
transcription from rna polymerase ii promoterGO:00063663680.023
detection of stimulusGO:00516061560.023
carboxylic acid metabolic processGO:0019752920.022
hormone catabolic processGO:004244730.022
negative regulation of cellular metabolic processGO:00313243820.022
Rat Fly
regulation of multicellular organismal developmentGO:20000264140.022
post embryonic appendage morphogenesisGO:00351203850.022
single organism biosynthetic processGO:00447112060.022
intracellular signal transductionGO:00355563000.022
cellular amine metabolic processGO:0044106120.021
positive regulation of nitrogen compound metabolic processGO:00511733540.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
Fly
regulation of transportGO:00510491810.021
single organism catabolic processGO:00447122280.021
compound eye developmentGO:00487493070.021
sensory perceptionGO:00076001960.021
gland developmentGO:00487321910.021
telencephalon developmentGO:002153720.021
regionalizationGO:00030024160.021
cellular amino acid metabolic processGO:0006520610.021
regulation of mitotic cell cycleGO:00073461900.021
epithelial cell differentiationGO:00308553220.021
neuron projection guidanceGO:00974852410.020
regulation of cell differentiationGO:00455953020.020
amine metabolic processGO:0009308120.020
macromolecular complex assemblyGO:00650032560.020
multi organism behaviorGO:00517051750.020
chemotaxisGO:00069352490.020
positive regulation of biosynthetic processGO:00098913160.020
positive regulation of cellular biosynthetic processGO:00313283160.020
compound eye morphogenesisGO:00017452490.020
ion transportGO:00068111450.020
neuron recognitionGO:00080381010.020
regulation of cell cycleGO:00517262910.020
negative regulation of developmental processGO:00510932010.020
camera type eye developmentGO:004301040.020
carbohydrate derivative metabolic processGO:19011352170.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of cellular ketone metabolic processGO:001056530.019
response to organophosphorusGO:004668320.019
kidney developmentGO:000182230.019
defense response to gram positive bacteriumGO:0050830410.019
phosphorylationGO:00163102940.019
cell divisionGO:00513012480.019
neurotransmitter metabolic processGO:004213320.019
meiotic cell cycleGO:00513211710.019
regulation of response to stressGO:00801342000.019
Rat
eye developmentGO:00016543230.019
positive regulation of nucleobase containing compound metabolic processGO:00459353320.019
heterocycle catabolic processGO:00467001660.019
axon developmentGO:00615642970.019
response to radiationGO:00093141550.018
axon guidanceGO:00074112330.018
transmembrane transportGO:00550851390.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
organophosphate metabolic processGO:00196371950.018
cellular ketone metabolic processGO:0042180240.018
mitotic nuclear divisionGO:00070672130.018
positive regulation of gene expressionGO:00106282900.018
positive regulation of macromolecule metabolic processGO:00106044050.018
detection of stimulus involved in sensory perceptionGO:0050906920.018
negative regulation of cell communicationGO:00106482230.018
Fly
detection of chemical stimulus involved in sensory perceptionGO:0050907750.018
innate immune responseGO:00450871440.018
regulation of transcription from rna polymerase ii promoterGO:00063573780.018
aromatic compound catabolic processGO:00194391660.018
eye morphogenesisGO:00485922600.017
purine ribonucleotide metabolic processGO:00091501450.017
cholesterol homeostasisGO:004263230.017
matingGO:00076181200.017
xenobiotic catabolic processGO:004217810.017
adult behaviorGO:00305341370.017
tube developmentGO:00352952440.017
morphogenesis of an epitheliumGO:00020092760.017
negative regulation of response to stimulusGO:00485852580.017
Rat Fly
regulation of phosphorus metabolic processGO:00511742100.017
exocrine system developmentGO:00352721620.017
gene silencingGO:00164581380.017
response to light stimulusGO:00094161240.016
purine containing compound metabolic processGO:00725211550.016
small gtpase mediated signal transductionGO:0007264880.016
organic cyclic compound catabolic processGO:19013611680.016
positive regulation of rna biosynthetic processGO:19026802660.016
lipid metabolic processGO:00066291210.016
benzene containing compound metabolic processGO:004253730.016
sensory perception of smellGO:0007608800.016
multi multicellular organism processGO:00447061230.016
regulation of cell cycle processGO:00105641810.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
nucleotide metabolic processGO:00091171610.016
regulation of cellular protein metabolic processGO:00322682430.016
Rat Fly
protein transportGO:00150311550.016
negative regulation of signalingGO:00230572190.016
Fly
spindle organizationGO:00070512530.016
negative regulation of signal transductionGO:00099682060.016
Fly
regulation of protein metabolic processGO:00512462560.016
Rat Fly
deathGO:00162652840.016
nucleoside phosphate metabolic processGO:00067531620.016
phosphate ion transportGO:000681740.016
positive regulation of transcription dna templatedGO:00458932660.016
establishment of protein localizationGO:00451841630.016
sensory organ morphogenesisGO:00905962600.016
regulation of multi organism processGO:00439001310.016
Fly
response to alcoholGO:0097305950.016
chaeta developmentGO:0022416970.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
negative regulation of rna metabolic processGO:00512532510.016
ovarian follicle cell developmentGO:00307072480.016
regulation of developmental growthGO:00486381740.016
regulation of catabolic processGO:00098941700.016
tissue deathGO:00162711020.016
negative regulation of biosynthetic processGO:00098902770.016
cytoplasmic transportGO:00164821300.015
cellular nitrogen compound catabolic processGO:00442701650.015
chemical homeostasisGO:0048878920.015
cell deathGO:00082192790.015
regulation of nervous system developmentGO:00519602480.015
response to extracellular stimulusGO:00099911160.015
Rat
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.015
chromatin organizationGO:00063252070.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
regulation of cell proliferationGO:00421271630.015
positive regulation of rna metabolic processGO:00512542710.015
salivary gland developmentGO:00074311620.015
ion transmembrane transportGO:00342201220.015
gland morphogenesisGO:00226121450.015
response to monosaccharideGO:003428440.015
programmed cell deathGO:00125012570.015
single organism intracellular transportGO:19025822070.015
regulation of cellular component biogenesisGO:00440872010.015
positive regulation of cell motilityGO:200014730.015
lateral inhibitionGO:00463312060.015
developmental maturationGO:00217001720.015
monocarboxylic acid transportGO:001571830.015
localization of cellGO:00516742570.015
multicellular organismal reproductive behaviorGO:00330571100.015
antimicrobial humoral responseGO:0019730990.015
Fly
l amino acid importGO:004309220.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
epithelial cell developmentGO:00020642740.015
regulation of cellular catabolic processGO:00313291570.015
humoral immune responseGO:00069591170.015
Fly
salivary gland morphogenesisGO:00074351450.015
reproductive behaviorGO:00190981220.015
macromolecule catabolic processGO:00090571610.014
purine nucleotide metabolic processGO:00061631460.014
ras protein signal transductionGO:0007265880.014
organonitrogen compound catabolic processGO:19015651280.014
detection of chemical stimulusGO:0009593930.014
synaptic target recognitionGO:0008039450.014
nucleobase containing small molecule metabolic processGO:00550861740.014
estrogen metabolic processGO:000821010.014
cell migrationGO:00164772380.014
regulation of intracellular signal transductionGO:19025312360.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
negative regulation of transcription dna templatedGO:00458922370.014
immune response activating signal transductionGO:000275720.014
response to hexoseGO:000974630.014
steroid catabolic processGO:000670610.014
cellular macromolecule localizationGO:00707272200.014
response to nutrient levelsGO:00316671140.014
Rat
columnar cuboidal epithelial cell developmentGO:00020662490.014
ethanolamine containing compound metabolic processGO:004243940.014
cell recognitionGO:00080371020.014
regulation of phosphate metabolic processGO:00192202100.014
cell adhesionGO:00071551360.014
Rat
embryonic development via the syncytial blastodermGO:00017001480.014
nucleobase containing compound catabolic processGO:00346551650.014
negative regulation of cellular biosynthetic processGO:00313272770.014
regulation of synapse structure and activityGO:00508031280.014
meiotic nuclear divisionGO:00071261510.014
open tracheal system developmentGO:00074242040.014
hematopoietic progenitor cell differentiationGO:000224410.014
ribonucleotide metabolic processGO:00092591450.014
proteolysisGO:00065081920.014
Rat Fly
protein complex assemblyGO:00064612000.014
organelle assemblyGO:00709251980.014
ribose phosphate metabolic processGO:00196931450.014
synaptic transmissionGO:00072682880.014
protein complex biogenesisGO:00702712010.014
salivary gland cell autophagic cell deathGO:0035071830.014
regulation of cellular localizationGO:00603411360.014
regulation of catalytic activityGO:00507901850.014
Rat Fly
cellular protein localizationGO:00346131600.014
regulation of gene expression epigeneticGO:00400291280.014
immune response regulating signaling pathwayGO:000276420.014
negative regulation of cell differentiationGO:00455961430.014
negative regulation of rna biosynthetic processGO:19026792400.014
response to glucoseGO:000974920.014
central nervous system developmentGO:00074172010.014
regulation of anatomical structure morphogenesisGO:00226032420.014
regulation of immune responseGO:00507761180.013
Fly
retina development in camera type eyeGO:006004140.013
cellular component assembly involved in morphogenesisGO:00109271510.013
developmental programmed cell deathGO:00106231380.013
defense response to fungusGO:0050832480.013
Fly
positive regulation of phosphorus metabolic processGO:00105621390.013
photoreceptor cell differentiationGO:00465301700.013
regulation of molecular functionGO:00650092170.013
Rat Fly
tissue morphogenesisGO:00487292970.013
regulation of epithelial cell proliferationGO:005067840.013
limb developmentGO:006017310.013
signal transduction by phosphorylationGO:00230141070.013
dna metabolic processGO:00062592270.013
cell cycle phase transitionGO:00447701400.013
regulation of notch signaling pathwayGO:00085931000.013
carbohydrate metabolic processGO:0005975820.013
cell motilityGO:00488702510.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of cell cycle phase transitionGO:19019871300.013
rna processingGO:00063961470.013
histolysisGO:00075591020.013
ribonucleoside metabolic processGO:00091191270.013
intracellular protein transportGO:00068861040.013
mapk cascadeGO:00001651070.013
chromatin modificationGO:00165681470.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
purine ribonucleoside metabolic processGO:00461281270.013
defense response to gram negative bacteriumGO:0050829940.013
Fly
acetylcholine metabolic processGO:000829120.013
purine nucleoside metabolic processGO:00422781270.013
salivary gland histolysisGO:0035070880.013
anion homeostasisGO:005508130.013
mitotic cell cycle phase transitionGO:00447721380.013
protein phosphorylationGO:00064681690.013
positive regulation of intracellular signal transductionGO:19025331160.013
inorganic ion transmembrane transportGO:0098660730.013
immune effector processGO:0002252980.013
Fly
chromosome segregationGO:00070591570.013
single organism cellular localizationGO:19025801800.013
negative regulation of multicellular organismal processGO:00512411420.013
hindbrain developmentGO:003090220.013
acetate ester metabolic processGO:190061920.013
compound eye photoreceptor cell differentiationGO:00017511400.013
locomotory behaviorGO:00076261760.013
cation transportGO:00068121100.013
response to nitrogen compoundGO:1901698900.012
axonogenesisGO:00074092900.012
anatomical structure homeostasisGO:0060249970.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
positive regulation of phosphate metabolic processGO:00459371390.012
negative regulation of cellular protein metabolic processGO:0032269850.012
Rat Fly
biological adhesionGO:00226101380.012
Rat
autophagic cell deathGO:0048102830.012
synapse organizationGO:00508081960.012
regulation of response to external stimulusGO:00321011150.012
Rat Fly
stem cell differentiationGO:00488631170.012
mitotic spindle organizationGO:00070522200.012
cellular response to dna damage stimulusGO:00069742230.012
segmentationGO:00352822070.012
regulation of growthGO:00400082330.012
connective tissue developmentGO:006144830.012
regulation of epithelial cell differentiationGO:003085640.012
actin filament based processGO:00300292200.012
regulation of phosphorylationGO:00423251470.012
regulation of mapk cascadeGO:0043408920.012
meiotic cell cycle processGO:19030461320.012
purine nucleotide catabolic processGO:00061951090.012
ameboidal type cell migrationGO:00016671510.012
wnt signaling pathwayGO:0016055980.012
regulation of defense responseGO:00313471020.012
Rat
regulation of cell developmentGO:00602842150.012
cellular macromolecule catabolic processGO:00442651360.012
organonitrogen compound biosynthetic processGO:19015661170.012
cellular response to ethanolGO:007136140.012
organophosphate catabolic processGO:00464341120.012
male gamete generationGO:00482322010.012
notch signaling pathwayGO:00072191200.012
intracellular protein transmembrane transportGO:006500240.012
somatic muscle developmentGO:0007525660.012
negative regulation of mitotic cell cycleGO:00459301090.012
tube morphogenesisGO:00352391910.012
response to organic cyclic compoundGO:0014070890.012
rhythmic processGO:00485111060.012
endomembrane system organizationGO:00102561190.012
secondary metabolic processGO:0019748750.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
positive regulation of immune system processGO:0002684680.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
synapse assemblyGO:00074161430.012
nucleoside catabolic processGO:00091641120.012
phosphatidylethanolamine metabolic processGO:004633710.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
pigment metabolic processGO:0042440840.012
embryo development ending in birth or egg hatchingGO:00097921520.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
response to woundingGO:0009611940.012
Rat
response to starvationGO:0042594970.012
axis specificationGO:00097981670.012
respiratory system developmentGO:00605412130.012
multi organism reproductive behaviorGO:00447051210.012
mating behaviorGO:00076171060.012
cell cycle checkpointGO:0000075950.012
ribonucleotide catabolic processGO:00092611090.011
carbohydrate derivative biosynthetic processGO:1901137850.011
nucleoside phosphate catabolic processGO:19012921100.011
autophagyGO:00069141080.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
protein transmembrane transportGO:007180640.011
negative regulation of protein metabolic processGO:0051248850.011
Rat Fly
nucleoside metabolic processGO:00091161270.011
female meiotic divisionGO:0007143700.011
negative regulation of cell cycleGO:00457861160.011
nicotinamide nucleotide metabolic processGO:004649620.011
eye photoreceptor cell differentiationGO:00017541450.011
spermatogenesisGO:00072832000.011
cellular homeostasisGO:0019725800.011
regulation of anatomical structure sizeGO:00900661630.011
purine containing compound catabolic processGO:00725231120.011
positive regulation of transportGO:0051050920.011
nucleoside triphosphate catabolic processGO:00091431080.011
response to endogenous stimulusGO:00097191190.011
androgen metabolic processGO:000820910.011
kidney epithelium developmentGO:007207330.011
blastoderm segmentationGO:00073501590.011
negative regulation of cell cycle processGO:00109481090.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
response to copper ionGO:004668840.011
negative regulation of cell cycle phase transitionGO:19019881030.011
cellular response to chemical stimulusGO:00708871990.011
chemosensory behaviorGO:00076351060.011
regulation of cell substrate adhesionGO:001081020.011
actin cytoskeleton organizationGO:00300362060.011
synaptic growth at neuromuscular junctionGO:00511241190.011
embryonic pattern specificationGO:00098801740.011
carbohydrate derivative catabolic processGO:19011361180.011
secretionGO:00469031090.011
choline catabolic processGO:004242610.011
purine ribonucleoside catabolic processGO:00461301120.011
cellular response to radiationGO:0071478520.011
stem cell developmentGO:0048864790.011
glycosyl compound catabolic processGO:19016581120.011
mesenchymal cell developmentGO:001403110.011
purine ribonucleotide catabolic processGO:00091541090.011
chromatin remodelingGO:0006338720.011
mrna metabolic processGO:00160711240.011
limb morphogenesisGO:003510810.011
positive regulation of cell migrationGO:003033520.011
multicellular organismal agingGO:00102591400.011
posttranscriptional regulation of gene expressionGO:00106081450.011
protein catabolic processGO:00301631010.011
regulation of organelle organizationGO:00330431960.011
negative regulation of nervous system developmentGO:0051961920.011
nucleoside triphosphate metabolic processGO:00091411200.011
dna integrity checkpointGO:0031570810.011
peptidyl amino acid modificationGO:00181931050.011
mitotic cell cycle checkpointGO:0007093880.011
organic hydroxy compound metabolic processGO:1901615830.011
nucleotide catabolic processGO:00091661090.011
positive regulation of cellular component organizationGO:00511301560.011
protein heterooligomerizationGO:005129140.011
glycosyl compound metabolic processGO:19016571270.010
nephron tubule developmentGO:007208030.010
single organism carbohydrate metabolic processGO:0044723720.010
response to organonitrogen compoundGO:0010243750.010
negative regulation of gene expression epigeneticGO:0045814770.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
peptide metabolic processGO:0006518800.010
Fly
positive regulation of lipid storageGO:001088440.010
dendrite developmentGO:00163582040.010
organelle localizationGO:00516401480.010
negative regulation of growthGO:0045926840.010
negative regulation of cellular component organizationGO:00511291080.010
polyol biosynthetic processGO:004617330.010
cellular lipid metabolic processGO:0044255830.010
positive regulation of cellular catabolic processGO:0031331950.010
purine nucleoside triphosphate metabolic processGO:00091441190.010
ribonucleoside catabolic processGO:00424541120.010
cellular biogenic amine catabolic processGO:004240210.010
protein modification by small protein conjugation or removalGO:00706471060.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010
drinking behaviorGO:004275620.010
choline metabolic processGO:001969510.010
dna damage checkpointGO:0000077780.010

Spn42Db disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.025
disease of metabolismDOID:001466700.019
inherited metabolic disorderDOID:65500.015
sensory system diseaseDOID:005015500.013
musculoskeletal system diseaseDOID:1700.013
cardiovascular system diseaseDOID:128700.013
eye diseaseDOID:561400.012
eye and adnexa diseaseDOID:149200.012
carbohydrate metabolism diseaseDOID:005001300.011
diabetes mellitusDOID:935100.011
acquired metabolic diseaseDOID:006015800.011
glucose metabolism diseaseDOID:419400.011
urinary system diseaseDOID:1800.011
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010