IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12985 (Dmel_CG12985)

CG12985 gene product from transcript CG12985-RA

(Aliases: Dmel\CG12985)

FLYBASE: FBgn0030881
Entrez: 32774
UniProtKB: Q9VX05

Process Predictions
Disease Predictions

CG12985 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
negative regulation of gene expression	GO:0010629	387	0.126
positive regulation of gene expression	GO:0010628	290	0.083
nuclear division	GO:0000280	332	0.073
cell recognition	GO:0008037	102	0.064
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.058
imaginal disc derived wing morphogenesis	GO:0007476	337	0.055
positive regulation of cellular biosynthetic process	GO:0031328	316	0.053
stem cell differentiation	GO:0048863	117	0.050
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.046
dendrite development	GO:0016358	204	0.046
positive regulation of biosynthetic process	GO:0009891	316	0.046
taxis	GO:0042330	304	0.043
meiotic nuclear division	GO:0007126	151	0.041
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.040
imaginal disc derived appendage development	GO:0048737	399	0.038
axonogenesis	GO:0007409	290	0.038
locomotory behavior	GO:0007626	176	0.036
wing disc morphogenesis	GO:0007472	344	0.036
negative regulation of developmental process	GO:0051093	201	0.034
chromosome organization	GO:0051276	360	0.031
body morphogenesis	GO:0010171	2	0.031
positive regulation of rna biosynthetic process	GO:1902680	266	0.030
actin filament based process	GO:0030029	220	0.030
forebrain development	GO:0030900	2	0.029
regulation of nervous system development	GO:0051960	248	0.028
chemosensory behavior	GO:0007635	106	0.028
axon development	GO:0061564	297	0.028
positive regulation of transcription dna templated	GO:0045893	266	0.027
positive regulation of rna metabolic process	GO:0051254	271	0.027
cellular component assembly involved in morphogenesis	GO:0010927	151	0.026
appendage development	GO:0048736	401	0.026
gland development	GO:0048732	191	0.026
dendrite morphogenesis	GO:0048813	199	0.026
cellular macromolecule localization	GO:0070727	220	0.025
stem cell development	GO:0048864	79	0.025
meiotic cell cycle process	GO:1903046	132	0.024
eye development	GO:0001654	323	0.024
negative regulation of cell differentiation	GO:0045596	143	0.023
response to hexose	GO:0009746	3	0.023
positive regulation of response to stimulus	GO:0048584	323	0.022
negative regulation of multicellular organismal process	GO:0051241	142	0.022
transcription from rna polymerase ii promoter	GO:0006366	368	0.022
macromolecule catabolic process	GO:0009057	161	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
regulation of cell cycle	GO:0051726	291	0.021
salivary gland development	GO:0007431	162	0.021
nucleoside phosphate metabolic process	GO:0006753	162	0.021
regulation of cellular ketone metabolic process	GO:0010565	3	0.021
regulation of neuron differentiation	GO:0045664	103	0.021
alditol phosphate metabolic process	GO:0052646	2	0.021
central nervous system development	GO:0007417	201	0.021
protein targeting to nucleus	GO:0044744	51	0.021
dna metabolic process	GO:0006259	227	0.020
post embryonic appendage morphogenesis	GO:0035120	385	0.020
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.020
gland morphogenesis	GO:0022612	145	0.020
generation of precursor metabolites and energy	GO:0006091	42	0.020
positive regulation of signaling	GO:0023056	243	0.020
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.020
male meiosis	GO:0007140	52	0.020
actin filament organization	GO:0007015	126	0.020
regulation of cell development	GO:0060284	215	0.020
response to organic substance	GO:0010033	284	0.020
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.019
regulation of multicellular organismal development	GO:2000026	414	0.019
single organism carbohydrate metabolic process	GO:0044723	72	0.019
regulation of organelle organization	GO:0033043	196	0.019
mitotic nuclear division	GO:0007067	213	0.019
growth	GO:0040007	359	0.019
myotube differentiation	GO:0014902	46	0.019
muscle structure development	GO:0061061	224	0.018
gene silencing	GO:0016458	138	0.018
chromosome segregation	GO:0007059	157	0.018
mating	GO:0007618	120	0.018
appendage morphogenesis	GO:0035107	397	0.018
cytokinesis	GO:0000910	90	0.018
cell death	GO:0008219	279	0.018
organelle assembly	GO:0070925	198	0.018
regulation of cell cycle process	GO:0010564	181	0.018
immune system process	GO:0002376	347	0.018
developmental programmed cell death	GO:0010623	138	0.017
negative regulation of growth	GO:0045926	84	0.017
compound eye development	GO:0048749	307	0.017
negative regulation of cellular biosynthetic process	GO:0031327	277	0.017
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.017
histolysis	GO:0007559	102	0.017
establishment of localization in cell	GO:0051649	402	0.017
protein complex assembly	GO:0006461	200	0.017
sister chromatid segregation	GO:0000819	92	0.016
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.016
developmental growth	GO:0048589	280	0.016
response to lipopolysaccharide	GO:0032496	4	0.016
cell division	GO:0051301	248	0.016
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.016
embryo development ending in birth or egg hatching	GO:0009792	152	0.016
androgen metabolic process	GO:0008209	1	0.016
nucleotide metabolic process	GO:0009117	161	0.016
camera type eye development	GO:0043010	4	0.016
segmentation	GO:0035282	207	0.016
synaptic growth at neuromuscular junction	GO:0051124	119	0.016
response to glucose	GO:0009749	2	0.015
organophosphate metabolic process	GO:0019637	195	0.015
amine metabolic process	GO:0009308	12	0.015
protein complex biogenesis	GO:0070271	201	0.015
chemotaxis	GO:0006935	249	0.015
salivary gland histolysis	GO:0035070	88	0.015
cognition	GO:0050890	141	0.015
immune system development	GO:0002520	57	0.015
death	GO:0016265	284	0.015
learning or memory	GO:0007611	141	0.015
female meiotic division	GO:0007143	70	0.015
salivary gland cell autophagic cell death	GO:0035071	83	0.015
negative regulation of insulin secretion	GO:0046676	1	0.015
benzene containing compound metabolic process	GO:0042537	3	0.014
regulation of neurogenesis	GO:0050767	158	0.014
spindle organization	GO:0007051	253	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
axon guidance	GO:0007411	233	0.014
exocrine system development	GO:0035272	162	0.014
response to monosaccharide	GO:0034284	4	0.014
posttranscriptional regulation of gene expression	GO:0010608	145	0.014
embryonic morphogenesis	GO:0048598	206	0.014
cellular response to oxygen containing compound	GO:1901701	79	0.014
mesenchymal cell differentiation	GO:0048762	1	0.014
olfactory behavior	GO:0042048	97	0.014
tissue death	GO:0016271	102	0.014
positive regulation of lipid storage	GO:0010884	4	0.014
phagocytosis	GO:0006909	215	0.014
neuromuscular junction development	GO:0007528	149	0.014
memory	GO:0007613	94	0.013
male meiosis chromosome segregation	GO:0007060	10	0.013
protein localization	GO:0008104	284	0.013
carbohydrate derivative biosynthetic process	GO:1901137	85	0.013
establishment of protein localization	GO:0045184	163	0.013
regulation of response to stress	GO:0080134	200	0.013
regulation of rna splicing	GO:0043484	69	0.013
small molecule metabolic process	GO:0044281	305	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
chromatin organization	GO:0006325	207	0.013
organ growth	GO:0035265	56	0.013
stem cell maintenance	GO:0019827	67	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
heart development	GO:0007507	82	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
regulation of intracellular transport	GO:0032386	64	0.013
negative regulation of rna metabolic process	GO:0051253	251	0.013
mitotic g2 m transition checkpoint	GO:0044818	70	0.012
neuron recognition	GO:0008038	101	0.012
organonitrogen compound metabolic process	GO:1901564	318	0.012
cellular macromolecular complex assembly	GO:0034622	153	0.012
kidney development	GO:0001822	3	0.012
syncytium formation by plasma membrane fusion	GO:0000768	43	0.012
negative regulation of biosynthetic process	GO:0009890	277	0.012
regulation of anatomical structure morphogenesis	GO:0022603	242	0.012
mrna metabolic process	GO:0016071	124	0.012
regulation of intracellular protein transport	GO:0033157	46	0.012
muscle organ development	GO:0007517	127	0.012
positive regulation of cell motility	GO:2000147	3	0.012
regulation of mrna splicing via spliceosome	GO:0048024	64	0.012
single organism intracellular transport	GO:1902582	207	0.012
g2 dna damage checkpoint	GO:0031572	69	0.012
synaptic target recognition	GO:0008039	45	0.012
single organism nuclear import	GO:1902593	51	0.012
epithelial cell differentiation	GO:0030855	322	0.012
cellular homeostasis	GO:0019725	80	0.012
organelle fission	GO:0048285	340	0.012
response to mercury ion	GO:0046689	3	0.012
eye photoreceptor cell differentiation	GO:0001754	145	0.012
protein phosphorylation	GO:0006468	169	0.011
regionalization	GO:0003002	416	0.011
purine ribonucleotide metabolic process	GO:0009150	145	0.011
regulation of synaptic transmission	GO:0050804	69	0.011
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.011
hormone catabolic process	GO:0042447	3	0.011
positive regulation of cell communication	GO:0010647	250	0.011
alternative mrna splicing via spliceosome	GO:0000380	60	0.011
cellular ketone metabolic process	GO:0042180	24	0.011
protein modification process	GO:0036211	438	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
developmental maturation	GO:0021700	172	0.011
carbohydrate derivative metabolic process	GO:1901135	217	0.011
regulation of developmental growth	GO:0048638	174	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
photoreceptor cell development	GO:0042461	96	0.011
nuclear import	GO:0051170	51	0.011
autophagic cell death	GO:0048102	83	0.011
cellular response to organic substance	GO:0071310	132	0.011
mitotic dna damage checkpoint	GO:0044773	74	0.011
response to copper ion	GO:0046688	4	0.011
protein targeting	GO:0006605	64	0.011
dephosphorylation	GO:0016311	51	0.011
meiotic cell cycle	GO:0051321	171	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.011
female meiosis chromosome segregation	GO:0016321	33	0.011
compound eye photoreceptor cell differentiation	GO:0001751	140	0.011
hematopoietic progenitor cell differentiation	GO:0002244	1	0.010
telencephalon development	GO:0021537	2	0.010
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.010
single organism cellular localization	GO:1902580	180	0.010
rna splicing via transesterification reactions	GO:0000375	73	0.010
neuron projection guidance	GO:0097485	241	0.010
neurotransmitter catabolic process	GO:0042135	1	0.010
regulation of transport	GO:0051049	181	0.010
skeletal muscle fiber development	GO:0048741	3	0.010
mesenchymal cell development	GO:0014031	1	0.010
regulation of protein metabolic process	GO:0051246	256	0.010
microtubule based movement	GO:0007018	51	0.010
photoreceptor cell differentiation	GO:0046530	170	0.010
cellular amine metabolic process	GO:0044106	12	0.010
protein import into nucleus	GO:0006606	51	0.010
regulation of mrna processing	GO:0050684	71	0.010

CG12985 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.013
carbohydrate metabolism disease	DOID:0050013	0.012
acquired metabolic disease	DOID:0060158	0.012
glucose metabolism disease	DOID:4194	0.012
musculoskeletal system disease	DOID:17	0.011
disease of anatomical entity	DOID:7	0.011
connective tissue disease	DOID:65	0.010
bone disease	DOID:0080001	0.010
nervous system disease	DOID:863	0.010

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