Drosophila melanogaster

37 known processes

Mlc2 (Dmel_CG2184)

Myosin light chain 2

(Aliases: MLC,CG2184,LC2,MLC 2,DmMLC2,mlc2,Ifm(3)99Eb,mlc-2,RLC,MLC2,RLC2,dro MLC-2,MYL2,MLC-2,Dmel\CG2184,l(3)99Eb,Dmlc2,MRLC)

Mlc2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sarcomere organizationGO:0045214260.993
myofibril assemblyGO:0030239360.945
striated muscle cell developmentGO:0055002500.910
muscle cell developmentGO:0055001500.809
muscle structure developmentGO:00610612240.792
cellular component assembly involved in morphogenesisGO:00109271510.786
actin cytoskeleton organizationGO:00300362060.771
actin filament based processGO:00300292200.575
striated muscle cell differentiationGO:0051146900.534
actomyosin structure organizationGO:0031032560.519
alditol phosphate metabolic processGO:005264620.430
body morphogenesisGO:001017120.408
muscle cell differentiationGO:00426921030.341
muscle thin filament assemblyGO:007168950.329
organelle assemblyGO:00709251980.316
adult behaviorGO:00305341370.311
cell motilityGO:00488702510.283
Fly
locomotory behaviorGO:00076261760.263
actin filament organizationGO:00070151260.263
regulation of actin filament depolymerizationGO:003083430.245
striated muscle myosin thick filament assemblyGO:007168830.227
glycerol 3 phosphate metabolic processGO:000607220.203
skeletal myofibril assemblyGO:001486660.180
circulatory system processGO:0003013370.170
regulation of anatomical structure morphogenesisGO:00226032420.165
skeletal muscle adaptationGO:004350110.162
nucleoside triphosphate catabolic processGO:00091431080.146
mitotic nuclear divisionGO:00070672130.143
somatic muscle developmentGO:0007525660.131
cell migrationGO:00164772380.130
Fly
muscle organ developmentGO:00075171270.123
regulation of actin filament lengthGO:0030832270.120
macromolecular complex assemblyGO:00650032560.118
skeletal muscle myosin thick filament assemblyGO:003024130.109
positive regulation of nucleoside metabolic processGO:0045979470.107
regulation of cytoskeleton organizationGO:0051493890.106
Fly
protein complex assemblyGO:00064612000.104
organophosphate metabolic processGO:00196371950.102
negative regulation of cytoskeleton organizationGO:0051494300.099
regulation of hydrolase activityGO:0051336970.098
cellular carbohydrate catabolic processGO:004427520.097
heart processGO:0003015370.092
negative regulation of actin filament depolymerizationGO:003083520.091
regulation of organelle organizationGO:00330431960.087
Fly
regulation of protein complex disassemblyGO:0043244290.087
camera type eye developmentGO:004301040.084
actin filament depolymerizationGO:003004250.083
skeletal muscle tissue developmentGO:0007519130.079
cellular protein complex disassemblyGO:0043624350.079
regulation of multicellular organismal developmentGO:20000264140.074
localization of cellGO:00516742570.072
Fly
multicellular organismal reproductive behaviorGO:00330571100.072
protein complex biogenesisGO:00702712010.071
positive regulation of cellular component organizationGO:00511301560.069
positive regulation of purine nucleotide catabolic processGO:0033123460.068
actin polymerization or depolymerizationGO:0008154310.068
larval developmentGO:00021641040.066
regulation of localizationGO:00328792750.066
regionalizationGO:00030024160.065
Fly
flight behaviorGO:0007629260.065
regulation of cell differentiationGO:00455953020.065
cellular macromolecular complex assemblyGO:00346221530.064
adult locomotory behaviorGO:0008344760.061
regulation of protein complex assemblyGO:0043254420.061
cellular protein complex assemblyGO:0043623710.061
regulation of actin filament based processGO:0032970420.061
Fly
muscle tissue morphogenesisGO:006041520.060
protein depolymerizationGO:0051261310.059
regulation of actin filament polymerizationGO:0030833250.059
brain developmentGO:00074201200.057
myotube cell developmentGO:001490430.057
organic substance catabolic processGO:19015753080.056
ribonucleoside catabolic processGO:00424541120.056
skeletal muscle fiber developmentGO:004874130.055
regulation of actin cytoskeleton organizationGO:0032956420.055
Fly
nucleotide catabolic processGO:00091661090.054
striated muscle tissue developmentGO:0014706270.053
multi multicellular organism processGO:00447061230.053
ribonucleoside triphosphate metabolic processGO:00091991190.052
actin filament polymerizationGO:0030041270.052
establishment of localization in cellGO:00516494020.051
Fly
positive regulation of macromolecule metabolic processGO:00106044050.051
purine nucleotide metabolic processGO:00061631460.051
male mating behaviorGO:0060179700.051
regulation of cellular catabolic processGO:00313291570.050
energy derivation by oxidation of organic compoundsGO:0015980320.050
positive regulation of atp catabolic processGO:190329130.049
actin filament cappingGO:005169320.048
purine nucleotide catabolic processGO:00061951090.048
regulation of organ growthGO:0046620420.047
nucleobase containing small molecule metabolic processGO:00550861740.046
single organism carbohydrate metabolic processGO:0044723720.046
regulation of actin polymerization or depolymerizationGO:0008064270.046
positive regulation of catabolic processGO:00098961050.045
regulation of protein depolymerizationGO:1901879270.045
nucleobase containing compound catabolic processGO:00346551650.044
negative regulation of actin filament polymerizationGO:003083770.044
carbohydrate derivative catabolic processGO:19011361180.042
ribonucleotide catabolic processGO:00092611090.041
regulation of system processGO:0044057360.041
endocytosisGO:00068973100.041
cellular catabolic processGO:00442483720.041
mesoderm developmentGO:0007498780.040
stem cell differentiationGO:00488631170.040
multi organism behaviorGO:00517051750.040
regulation of cell developmentGO:00602842150.040
rna processingGO:00063961470.039
cellular nitrogen compound catabolic processGO:00442701650.039
skeletal muscle organ developmentGO:0060538480.038
regulation of cell deathGO:00109411730.038
cation homeostasisGO:0055080510.037
eye developmentGO:00016543230.037
positive regulation of multicellular organismal processGO:00512401430.037
protein modification processGO:00362114380.037
negative regulation of protein complex disassemblyGO:0043242230.037
regulation of cellular component sizeGO:0032535980.037
response to abiotic stimulusGO:00096283410.036
larval somatic muscle developmentGO:0007526190.035
regulation of catabolic processGO:00098941700.035
appendage developmentGO:00487364010.035
Fly
aromatic compound catabolic processGO:00194391660.034
ovulationGO:003072840.034
carbohydrate derivative metabolic processGO:19011352170.034
cell deathGO:00082192790.034
glycosyl compound metabolic processGO:19016571270.033
purine nucleoside metabolic processGO:00422781270.033
macromolecular complex disassemblyGO:0032984370.032
nucleoside triphosphate metabolic processGO:00091411200.031
muscle contractionGO:0006936130.031
heterocycle catabolic processGO:00467001660.031
muscle attachmentGO:0016203360.031
heart contractionGO:0060047260.030
regulation of cellular localizationGO:00603411360.030
regulation of phosphorus metabolic processGO:00511742100.030
purine ribonucleoside triphosphate catabolic processGO:00092071080.030
catabolic processGO:00090564090.030
purine ribonucleoside triphosphate metabolic processGO:00092051190.029
nucleotide metabolic processGO:00091171610.029
purine ribonucleoside metabolic processGO:00461281270.029
programmed cell deathGO:00125012570.029
negative regulation of cell cycleGO:00457861160.029
purine nucleoside triphosphate catabolic processGO:00091461080.028
ribonucleoside monophosphate catabolic processGO:0009158390.028
positive regulation of molecular functionGO:00440931360.028
positive regulation of actin filament polymerizationGO:0030838110.027
negative regulation of cellular component organizationGO:00511291080.027
cell cell junction organizationGO:0045216550.027
carbohydrate biosynthetic processGO:0016051170.027
ribose phosphate metabolic processGO:00196931450.027
glycosyl compound catabolic processGO:19016581120.027
adult somatic muscle developmentGO:0007527140.026
cellular respirationGO:0045333260.026
cellular protein localizationGO:00346131600.026
protein polymerizationGO:0051258420.026
nucleoside phosphate metabolic processGO:00067531620.026
cardiac muscle tissue developmentGO:004873890.026
purine containing compound catabolic processGO:00725231120.025
negative regulation of gene expressionGO:00106293870.025
regulation of cellular amine metabolic processGO:003323830.025
regulation of apoptotic processGO:00429811300.024
maintenance of locationGO:0051235730.024
wing disc morphogenesisGO:00074723440.024
Fly
intracellular transportGO:00469072280.024
Fly
nucleoside catabolic processGO:00091641120.024
regulation of anatomical structure sizeGO:00900661630.024
Fly
rna localizationGO:00064031150.024
epithelial cell differentiationGO:00308553220.024
Fly
striated muscle adaptationGO:001488810.024
regulation of nucleoside metabolic processGO:0009118500.023
electron transport chainGO:0022900140.023
rna splicingGO:0008380830.023
regulation of nucleotide catabolic processGO:0030811480.023
positive regulation of phosphorus metabolic processGO:00105621390.023
regulation of cellular ketone metabolic processGO:001056530.022
regulation of growthGO:00400082330.022
regulation of phosphate metabolic processGO:00192202100.021
purine nucleoside catabolic processGO:00061521120.021
protein localizationGO:00081042840.021
phagocytosisGO:00069092150.021
organonitrogen compound catabolic processGO:19015651280.021
small molecule metabolic processGO:00442813050.021
positive regulation of phosphate metabolic processGO:00459371390.021
mitochondrial transportGO:000683980.021
oxidation reduction processGO:00551141230.020
striated muscle contractionGO:000694150.020
regulation of transportGO:00510491810.020
musculoskeletal movementGO:005088130.020
chromosome segregationGO:00070591570.020
multi organism reproductive behaviorGO:00447051210.020
regulation of synapse organizationGO:00508071100.020
purine nucleoside triphosphate metabolic processGO:00091441190.019
cellular component disassemblyGO:0022411460.019
negative regulation of cellular metabolic processGO:00313243820.019
regulation of heart contractionGO:0008016210.019
purine ribonucleoside monophosphate catabolic processGO:0009169380.019
organelle fissionGO:00482853400.019
growthGO:00400073590.019
Fly
regulation of cellular component biogenesisGO:00440872010.019
regulation of cysteine type endopeptidase activityGO:2000116270.018
purine ribonucleotide metabolic processGO:00091501450.018
inorganic cation transmembrane transportGO:0098662610.018
synapse organizationGO:00508081960.018
negative regulation of molecular functionGO:0044092510.018
telencephalon developmentGO:002153720.018
regulation of protein polymerizationGO:0032271280.018
positive regulation of purine nucleotide metabolic processGO:1900544550.018
single organism intracellular transportGO:19025822070.018
Fly
organonitrogen compound metabolic processGO:19015643180.018
positive regulation of hydrolase activityGO:0051345780.018
regulation of sarcomere organizationGO:006029720.017
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.017
regulation of catalytic activityGO:00507901850.017
regulation of cell cycle processGO:00105641810.017
regulation of rna splicingGO:0043484690.017
embryo development ending in birth or egg hatchingGO:00097921520.017
Fly
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
compound eye morphogenesisGO:00017452490.017
negative regulation of organelle organizationGO:0010639560.017
cell proliferationGO:00082832990.017
mrna processingGO:00063971040.017
positive regulation of apoptotic processGO:0043065470.017
oxoacid metabolic processGO:00434361030.017
cardiovascular system developmentGO:0072358820.017
vesicle mediated transportGO:00161923810.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
actin filament based movementGO:0030048260.016
Fly
regulation of nucleocytoplasmic transportGO:0046822350.016
purine containing compound metabolic processGO:00725211550.016
heart developmentGO:0007507820.016
purine nucleoside monophosphate catabolic processGO:0009128380.016
organic cyclic compound catabolic processGO:19013611680.016
regulation of purine nucleotide metabolic processGO:1900542620.016
germarium derived egg chamber formationGO:00072931010.016
mrna metabolic processGO:00160711240.016
muscle tissue developmentGO:0060537300.016
positive regulation of catalytic activityGO:00430851180.016
developmental maturationGO:00217001720.016
regulation of molecular functionGO:00650092170.015
response to oxygen levelsGO:0070482590.015
macromolecule catabolic processGO:00090571610.015
regulation of establishment of protein localizationGO:0070201610.015
positive regulation of nucleotide metabolic processGO:0045981550.015
purine ribonucleoside catabolic processGO:00461301120.015
negative regulation of phosphorus metabolic processGO:0010563450.015
cellular response to starvationGO:0009267610.015
carbohydrate metabolic processGO:0005975820.015
muscle system processGO:0003012210.015
regulation of purine nucleotide catabolic processGO:0033121480.015
nucleoside metabolic processGO:00091161270.014
positive regulation of nucleotide catabolic processGO:0030813460.014
regulation of cell cycleGO:00517262910.014
ovipositionGO:0018991190.014
posttranscriptional regulation of gene expressionGO:00106081450.014
regulation of nucleotide metabolic processGO:0006140620.014
nuclear transportGO:0051169720.014
response to lipopolysaccharideGO:003249640.014
stem cell developmentGO:0048864790.014
muscle adaptationGO:004350010.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.014
purine ribonucleoside monophosphate metabolic processGO:0009167500.014
detection of chemical stimulusGO:0009593930.014
regulation of programmed cell deathGO:00430671520.013
circulatory system developmentGO:0072359820.013
regulation of cellular amino acid metabolic processGO:000652100.013
ion transportGO:00068111450.013
imaginal disc derived appendage developmentGO:00487373990.013
Fly
cardiac muscle cell differentiationGO:005500740.013
cortical cytoskeleton organizationGO:0030865290.013
tissue morphogenesisGO:00487292970.013
nucleoside monophosphate metabolic processGO:0009123520.013
organophosphate catabolic processGO:00464341120.013
muscle fiber developmentGO:0048747120.013
regulation of nervous system developmentGO:00519602480.013
nucleoside phosphate catabolic processGO:19012921100.013
positive regulation of cellular component biogenesisGO:0044089800.012
negative regulation of apoptotic processGO:0043066630.012
negative regulation of protein polymerizationGO:003227270.012
notch signaling pathwayGO:00072191200.012
negative regulation of nitrogen compound metabolic processGO:00511722650.012
blood circulationGO:0008015260.012
single organism cellular localizationGO:19025801800.012
negative regulation of protein depolymerizationGO:1901880230.012
respiratory electron transport chainGO:0022904110.012
multicellular organism growthGO:0035264460.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
nucleoside monophosphate catabolic processGO:0009125390.012
cellular response to organic cyclic compoundGO:0071407320.012
ribonucleoside metabolic processGO:00091191270.012
negative regulation of cellular catabolic processGO:0031330340.012
ribonucleotide metabolic processGO:00092591450.012
cytoplasm organizationGO:0007028640.012
positive regulation of cytoskeleton organizationGO:0051495210.011
apoptotic processGO:00069151590.011
biological adhesionGO:00226101380.011
single organism behaviorGO:00447083910.011
single organism nuclear importGO:1902593510.011
regulation of cell projection organizationGO:0031344920.011
cytoplasmic transport nurse cell to oocyteGO:0007303120.011
Fly
adherens junction organizationGO:0034332270.011
alternative mrna splicing via spliceosomeGO:0000380600.011
compound eye developmentGO:00487493070.011
cellular macromolecule localizationGO:00707272200.011
segmentationGO:00352822070.011
nucleocytoplasmic transportGO:0006913720.011
sister chromatid cohesionGO:0007062180.011
organic acid metabolic processGO:00060821030.011
purine ribonucleotide catabolic processGO:00091541090.011
positive regulation of gtpase activityGO:0043547430.010
anterior posterior axis specificationGO:00099481090.010
cytokinesisGO:0000910900.010
Fly
germarium derived female germ line cyst formationGO:0030727420.010
protein catabolic processGO:00301631010.010
sister chromatid segregationGO:0000819920.010
atp metabolic processGO:0046034490.010
actin cytoskeleton reorganizationGO:0031532220.010
transmembrane transportGO:00550851390.010
regulation of developmental growthGO:00486381740.010
cellular amino acid metabolic processGO:0006520610.010
wound healingGO:0042060750.010
Fly

Mlc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.123
heart diseaseDOID:11400.123
cardiomyopathyDOID:005070000.123
myopathyDOID:42300.123
intrinsic cardiomyopathyDOID:006003600.123
cardiovascular system diseaseDOID:128700.123
muscle tissue diseaseDOID:6600.123
musculoskeletal system diseaseDOID:1700.123
muscular diseaseDOID:008000000.123
dilated cardiomyopathyDOID:1293000.067
nervous system diseaseDOID:86300.015
neurodegenerative diseaseDOID:128900.015
central nervous system diseaseDOID:33100.015