IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG1986 (Dmel_CG1986)

CG1986 gene product from transcript CG1986-RA

(Aliases: Dmel\CG1986)

Entrez: 31925
FLYBASE: FBgn0030162
UniProtKB: Q9W304

Process Predictions
Disease Predictions

CG1986 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
oxoacid metabolic process	GO:0043436	103	0.113	Human Rat
cellular amino acid metabolic process	GO:0006520	61	0.099	Rat
small molecule metabolic process	GO:0044281	305	0.090	Human Rat
organonitrogen compound metabolic process	GO:1901564	318	0.087	Rat
carboxylic acid metabolic process	GO:0019752	92	0.086	Human Rat
cellular protein modification process	GO:0006464	438	0.077
cellular amine metabolic process	GO:0044106	12	0.071	Rat
amine metabolic process	GO:0009308	12	0.064	Rat
cellular ketone metabolic process	GO:0042180	24	0.062
regulation of cellular ketone metabolic process	GO:0010565	3	0.061
single organism biosynthetic process	GO:0044711	206	0.061	Human Rat
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.060
negative regulation of gene expression	GO:0010629	387	0.055
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.054
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.054
g protein coupled receptor signaling pathway	GO:0007186	136	0.053
protein modification process	GO:0036211	438	0.052
positive regulation of biosynthetic process	GO:0009891	316	0.050
regulation of cellular amine metabolic process	GO:0033238	3	0.047
positive regulation of macromolecule metabolic process	GO:0010604	405	0.047
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.045
chromosome organization	GO:0051276	360	0.045
immune response	GO:0006955	246	0.045
cell death	GO:0008219	279	0.044
wing disc morphogenesis	GO:0007472	344	0.044	Fly
positive regulation of response to stimulus	GO:0048584	323	0.043
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.043
defense response	GO:0006952	300	0.042
negative regulation of cellular biosynthetic process	GO:0031327	277	0.042
positive regulation of cellular biosynthetic process	GO:0031328	316	0.042
response to abiotic stimulus	GO:0009628	341	0.040	Rat
response to other organism	GO:0051707	293	0.040
negative regulation of biosynthetic process	GO:0009890	277	0.038
regulation of notch signaling pathway	GO:0008593	100	0.038
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.038
positive regulation of signal transduction	GO:0009967	223	0.038
gland morphogenesis	GO:0022612	145	0.037
negative regulation of rna metabolic process	GO:0051253	251	0.037
positive regulation of cell communication	GO:0010647	250	0.037
defense response to other organism	GO:0098542	225	0.037
transcription from rna polymerase ii promoter	GO:0006366	368	0.036
response to biotic stimulus	GO:0009607	294	0.036
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.036
programmed cell death	GO:0012501	257	0.035
negative regulation of transcription dna templated	GO:0045892	237	0.033
developmental programmed cell death	GO:0010623	138	0.033
gland development	GO:0048732	191	0.033	Rat
innate immune response	GO:0045087	144	0.032
histolysis	GO:0007559	102	0.032
death	GO:0016265	284	0.032
organic acid metabolic process	GO:0006082	103	0.031	Human Rat
negative regulation of rna biosynthetic process	GO:1902679	240	0.031
salivary gland development	GO:0007431	162	0.031
positive regulation of signaling	GO:0023056	243	0.030
negative regulation of cellular metabolic process	GO:0031324	382	0.030
positive regulation of transcription dna templated	GO:0045893	266	0.030
gliogenesis	GO:0042063	80	0.029
immune system process	GO:0002376	347	0.029
defense response to bacterium	GO:0042742	178	0.029
response to organic substance	GO:0010033	284	0.028	Rat
response to external biotic stimulus	GO:0043207	293	0.028
salivary gland cell autophagic cell death	GO:0035071	83	0.028
notch signaling pathway	GO:0007219	120	0.028
autophagic cell death	GO:0048102	83	0.027
intracellular signal transduction	GO:0035556	300	0.027
organic substance catabolic process	GO:1901575	308	0.027	Human Rat
pigment metabolic process	GO:0042440	84	0.027
regulation of organelle organization	GO:0033043	196	0.027
positive regulation of rna biosynthetic process	GO:1902680	266	0.026
positive regulation of gene expression	GO:0010628	290	0.026
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.025
single organism catabolic process	GO:0044712	228	0.024	Human Rat
tissue death	GO:0016271	102	0.024
protein acetylation	GO:0006473	39	0.024
homeostatic process	GO:0042592	199	0.024	Human
salivary gland morphogenesis	GO:0007435	145	0.023
positive regulation of rna metabolic process	GO:0051254	271	0.023
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.022	Fly
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.022
response to oxygen containing compound	GO:1901700	200	0.022	Rat
organic hydroxy compound metabolic process	GO:1901615	83	0.022	Rat
regulation of cellular amino acid metabolic process	GO:0006521	0	0.022
post embryonic appendage morphogenesis	GO:0035120	385	0.022	Fly
catabolic process	GO:0009056	409	0.022	Human Rat
detection of external stimulus	GO:0009581	66	0.022
response to radiation	GO:0009314	155	0.022
salivary gland histolysis	GO:0035070	88	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
defense response to gram negative bacterium	GO:0050829	94	0.021
response to lipopolysaccharide	GO:0032496	4	0.021
phosphorylation	GO:0016310	294	0.021
histone acetylation	GO:0016573	38	0.021
regulation of response to stress	GO:0080134	200	0.020
exocrine system development	GO:0035272	162	0.020
covalent chromatin modification	GO:0016569	106	0.020
histone modification	GO:0016570	106	0.020
mitotic nuclear division	GO:0007067	213	0.019
response to bacterium	GO:0009617	198	0.019
establishment of localization in cell	GO:0051649	402	0.019
regulation of cell cycle	GO:0051726	291	0.019
regulation of chromatin organization	GO:1902275	32	0.019
organonitrogen compound biosynthetic process	GO:1901566	117	0.019
regulation of cell differentiation	GO:0045595	302	0.019
anatomical structure homeostasis	GO:0060249	97	0.019
cell proliferation	GO:0008283	299	0.019	Rat
negative regulation of response to stimulus	GO:0048585	258	0.019
connective tissue development	GO:0061448	3	0.018
taxis	GO:0042330	304	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.018
peptidyl amino acid modification	GO:0018193	105	0.018
peptidyl lysine modification	GO:0018205	57	0.018
negative regulation of cellular component organization	GO:0051129	108	0.018
negative regulation of protein metabolic process	GO:0051248	85	0.018
pigmentation	GO:0043473	75	0.017
cell recognition	GO:0008037	102	0.017
organophosphate metabolic process	GO:0019637	195	0.017	Rat
monocarboxylic acid transport	GO:0015718	3	0.017
detection of light stimulus	GO:0009583	58	0.017
nitrogen compound transport	GO:0071705	85	0.017
regionalization	GO:0003002	416	0.017
regulation of anatomical structure morphogenesis	GO:0022603	242	0.017
negative regulation of chromosome organization	GO:2001251	19	0.017
detection of stimulus	GO:0051606	156	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.016	Rat
photoreceptor cell differentiation	GO:0046530	170	0.016
cell division	GO:0051301	248	0.016
male gamete generation	GO:0048232	201	0.016
regulation of protein metabolic process	GO:0051246	256	0.016
histone lysine methylation	GO:0034968	32	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
response to organophosphorus	GO:0046683	2	0.016
developmental maturation	GO:0021700	172	0.016
sterol homeostasis	GO:0055092	4	0.016	Human
regulation of chromosome organization	GO:0033044	64	0.016
regulation of catalytic activity	GO:0050790	185	0.016
vesicle mediated transport	GO:0016192	381	0.016	Fly
anion homeostasis	GO:0055081	3	0.016	Human
pigment metabolic process involved in pigmentation	GO:0043474	33	0.015
cholesterol transport	GO:0030301	2	0.015	Human
compound eye development	GO:0048749	307	0.015
single organism intracellular transport	GO:1902582	207	0.015
cellular catabolic process	GO:0044248	372	0.015	Human Rat
imaginal disc derived appendage development	GO:0048737	399	0.015	Fly
phagocytosis	GO:0006909	215	0.015	Fly
nuclear division	GO:0000280	332	0.015
regulation of transport	GO:0051049	181	0.015	Human
adult behavior	GO:0030534	137	0.015
spermatogenesis	GO:0007283	200	0.015
regulation of immune response	GO:0050776	118	0.015
chemotaxis	GO:0006935	249	0.015
protein alkylation	GO:0008213	43	0.015
eye pigment metabolic process	GO:0042441	33	0.015
regulation of developmental growth	GO:0048638	174	0.015
cellular response to dna damage stimulus	GO:0006974	223	0.015
cholesterol homeostasis	GO:0042632	3	0.015	Human
regulation of multicellular organismal development	GO:2000026	414	0.015
dendrite development	GO:0016358	204	0.015
cellular response to extracellular stimulus	GO:0031668	64	0.015
compound eye morphogenesis	GO:0001745	249	0.014
l amino acid import	GO:0043092	2	0.014
maintenance of location	GO:0051235	73	0.014	Human
camera type eye development	GO:0043010	4	0.014
cellular response to lipopolysaccharide	GO:0071222	3	0.014
regulation of programmed cell death	GO:0043067	152	0.014
detection of abiotic stimulus	GO:0009582	66	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
regulation of immune system process	GO:0002682	176	0.014
appendage development	GO:0048736	401	0.014	Fly
cellular lipid metabolic process	GO:0044255	83	0.014	Human Rat
cellular response to molecule of bacterial origin	GO:0071219	3	0.014
immune response activating signal transduction	GO:0002757	2	0.014
negative regulation of developmental process	GO:0051093	201	0.014
multicellular organismal aging	GO:0010259	140	0.014
cognition	GO:0050890	141	0.014
protein complex biogenesis	GO:0070271	201	0.014	Rat
regulation of mitotic cell cycle	GO:0007346	190	0.014
response to decreased oxygen levels	GO:0036293	58	0.014	Rat
ion transport	GO:0006811	145	0.014
eye photoreceptor cell differentiation	GO:0001754	145	0.013
protein complex assembly	GO:0006461	200	0.013	Rat
sodium dependent phosphate transport	GO:0044341	2	0.013
regulation of sequestering of triglyceride	GO:0010889	3	0.013	Human
spermatid differentiation	GO:0048515	114	0.013
chemosensory behavior	GO:0007635	106	0.013
forebrain development	GO:0030900	2	0.013
cytoplasmic transport	GO:0016482	130	0.013
negative regulation of cell cycle	GO:0045786	116	0.013
telencephalon development	GO:0021537	2	0.013
response to light stimulus	GO:0009416	124	0.013
morphogenesis of an epithelium	GO:0002009	276	0.013
imaginal disc derived wing morphogenesis	GO:0007476	337	0.013	Fly
carbohydrate derivative biosynthetic process	GO:1901137	85	0.013	Rat
axon development	GO:0061564	297	0.013
cation transport	GO:0006812	110	0.013
cellular response to biotic stimulus	GO:0071216	4	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
negative regulation of immune response	GO:0050777	39	0.013
organic substance transport	GO:0071702	257	0.013	Human
imaginal disc pattern formation	GO:0007447	91	0.013
regulation of histone modification	GO:0031056	20	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.012
phosphatidylethanolamine metabolic process	GO:0046337	1	0.012	Rat
vitamin metabolic process	GO:0006766	2	0.012
neurological system process	GO:0050877	358	0.012
single organism behavior	GO:0044708	391	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.012	Rat
cellular response to light stimulus	GO:0071482	37	0.012
neuron recognition	GO:0008038	101	0.012
regulation of cell morphogenesis	GO:0022604	163	0.012
macromolecular complex assembly	GO:0065003	256	0.012	Rat
determination of adult lifespan	GO:0008340	137	0.012
eye morphogenesis	GO:0048592	260	0.012
signal transduction by phosphorylation	GO:0023014	107	0.012
triglyceride biosynthetic process	GO:0019432	2	0.012	Rat
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
aging	GO:0007568	143	0.012
sex differentiation	GO:0007548	81	0.012
phototransduction visible light	GO:0007603	27	0.012
regulation of lipid transport	GO:0032368	3	0.012	Human
transmembrane transport	GO:0055085	139	0.012
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.012
intracellular transport	GO:0046907	228	0.012
developmental growth	GO:0048589	280	0.012	Rat
regulation of innate immune response	GO:0045088	71	0.012
response to oxygen levels	GO:0070482	59	0.012	Rat
long term memory	GO:0007616	62	0.012
axonogenesis	GO:0007409	290	0.012
compound eye photoreceptor cell differentiation	GO:0001751	140	0.012
organelle assembly	GO:0070925	198	0.012
chemical homeostasis	GO:0048878	92	0.012	Human
negative regulation of organelle organization	GO:0010639	56	0.012
regulation of chromatin modification	GO:1903308	28	0.012
phosphate ion transport	GO:0006817	4	0.011
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.011
central nervous system development	GO:0007417	201	0.011
response to copper ion	GO:0046688	4	0.011	Rat
detection of stimulus involved in sensory perception	GO:0050906	92	0.011
cellular response to organic substance	GO:0071310	132	0.011	Rat
apoptotic process	GO:0006915	159	0.011
response to wounding	GO:0009611	94	0.011
positive regulation of notch signaling pathway	GO:0045747	34	0.011
sensory organ morphogenesis	GO:0090596	260	0.011
cellular homeostasis	GO:0019725	80	0.011
mapk cascade	GO:0000165	107	0.011
cation transmembrane transport	GO:0098655	88	0.011
eye pigmentation	GO:0048069	43	0.011
humoral immune response	GO:0006959	117	0.011
lipid biosynthetic process	GO:0008610	46	0.011	Human Rat
cellular response to chemical stimulus	GO:0070887	199	0.011	Rat
cytokinesis	GO:0000910	90	0.011
actin filament based process	GO:0030029	220	0.011
positive regulation of cell migration	GO:0030335	2	0.011
segmentation	GO:0035282	207	0.011
regulation of cell proliferation	GO:0042127	163	0.011
biological adhesion	GO:0022610	138	0.011
kidney development	GO:0001822	3	0.011
protein acylation	GO:0043543	42	0.011
embryonic development via the syncytial blastoderm	GO:0001700	148	0.011
protein localization	GO:0008104	284	0.011
cell adhesion	GO:0007155	136	0.011
response to inorganic substance	GO:0010035	44	0.011	Rat
chromosome segregation	GO:0007059	157	0.011
body morphogenesis	GO:0010171	2	0.011
eye photoreceptor cell development	GO:0042462	81	0.011
embryonic pattern specification	GO:0009880	174	0.011
cellular response to radiation	GO:0071478	52	0.011
methylation	GO:0032259	47	0.011
olfactory behavior	GO:0042048	97	0.011
proteolysis	GO:0006508	192	0.010
glycoprotein metabolic process	GO:0009100	41	0.010	Rat
photoreceptor cell development	GO:0042461	96	0.010
columnar cuboidal epithelial cell development	GO:0002066	249	0.010
rna processing	GO:0006396	147	0.010
gene silencing	GO:0016458	138	0.010
retina development in camera type eye	GO:0060041	4	0.010
pigment biosynthetic process	GO:0046148	36	0.010
regulation of phosphorylation	GO:0042325	147	0.010
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.010
regulation of cell death	GO:0010941	173	0.010
growth	GO:0040007	359	0.010	Rat
open tracheal system development	GO:0007424	204	0.010
regulation of cell cycle process	GO:0010564	181	0.010
anion transport	GO:0006820	41	0.010
positive regulation of immune response	GO:0050778	63	0.010
ovarian follicle cell development	GO:0030707	248	0.010
epithelial cell differentiation	GO:0030855	322	0.010
endocytosis	GO:0006897	310	0.010	Fly
organic cyclic compound catabolic process	GO:1901361	168	0.010
mrna metabolic process	GO:0016071	124	0.010
positive regulation of phosphorylation	GO:0042327	87	0.010

CG1986 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.030	Human
acquired metabolic disease	DOID:0060158	0.023	Human
disease of metabolism	DOID:0014667	0.023	Human
cardiovascular system disease	DOID:1287	0.020
amyloidosis	DOID:9120	0.018
familial visceral amyloidosis	DOID:0050636	0.018
inherited metabolic disorder	DOID:655	0.015	Human
nervous system disease	DOID:863	0.012
diabetes mellitus	DOID:9351	0.011	Human
glucose metabolism disease	DOID:4194	0.011	Human
carbohydrate metabolism disease	DOID:0050013	0.011	Human
type 2 diabetes mellitus	DOID:9352	0.011	Human

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