Drosophila melanogaster

128 known processes

pcm (Dmel_CG3291)

pacman

(Aliases: CG3291,Xrn1p,XRN1/pcm,Xrn1,Dmel\CG3291,Pcm,XRN1)

pcm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of gene expressionGO:00106293870.376
regulation of multi organism processGO:00439001310.179
tissue morphogenesisGO:00487292970.143
nuclear divisionGO:00002803320.116
vesicle mediated transportGO:00161923810.099
ncrna 3 end processingGO:0043628170.098
positive regulation of macromolecule biosynthetic processGO:00105572830.097
regulation of response to stressGO:00801342000.087
positive regulation of response to stimulusGO:00485843230.086
chromosome organizationGO:00512763600.083
single organism intracellular transportGO:19025822070.081
homeostatic processGO:00425921990.078
cell proliferationGO:00082832990.078
developmental growthGO:00485892800.077
gland developmentGO:00487321910.075
protein complex assemblyGO:00064612000.072
regulation of cell cycle processGO:00105641810.070
snrna metabolic processGO:0016073140.070
regulation of immune system processGO:00026821760.069
negative regulation of biosynthetic processGO:00098902770.068
dna metabolic processGO:00062592270.068
positive regulation of signalingGO:00230562430.064
establishment of localization in cellGO:00516494020.062
embryonic morphogenesisGO:00485982060.059
negative regulation of cellular biosynthetic processGO:00313272770.059
negative regulation of apoptotic processGO:0043066630.057
negative regulation of nitrogen compound metabolic processGO:00511722650.056
transcription from rna polymerase ii promoterGO:00063663680.056
sperm individualizationGO:0007291480.055
regulation of localizationGO:00328792750.054
mitotic nuclear divisionGO:00070672130.054
negative regulation of macromolecule biosynthetic processGO:00105582700.052
regulation of transcription from rna polymerase ii promoterGO:00063573780.052
positive regulation of rna biosynthetic processGO:19026802660.049
male gamete generationGO:00482322010.049
spermatid developmentGO:0007286980.048
response to abiotic stimulusGO:00096283410.047
ncrna metabolic processGO:0034660430.046
Human
endocytosisGO:00068973100.045
regulation of cell morphogenesisGO:00226041630.044
organelle fissionGO:00482853400.042
determination of adult lifespanGO:00083401370.042
embryonic pattern specificationGO:00098801740.041
defense responseGO:00069523000.039
regulation of mitotic cell cycleGO:00073461900.039
positive regulation of protein metabolic processGO:00512471280.038
positive regulation of gene expressionGO:00106282900.038
posttranscriptional gene silencing by rnaGO:0035194450.038
regulation of molecular functionGO:00650092170.038
chromatin modificationGO:00165681470.038
centrosome organizationGO:00512971630.037
positive regulation of nucleobase containing compound metabolic processGO:00459353320.035
regulation of cell differentiationGO:00455953020.035
regulation of response to external stimulusGO:00321011150.033
gene silencing by rnaGO:0031047570.032
positive regulation of nucleic acid templated transcriptionGO:19035082660.032
connective tissue developmentGO:006144830.032
stem cell proliferationGO:0072089880.032
cellular catabolic processGO:00442483720.031
intracellular transportGO:00469072280.031
regulation of cellular component biogenesisGO:00440872010.031
post embryonic appendage morphogenesisGO:00351203850.030
regulation of cellular amine metabolic processGO:003323830.030
positive regulation of cellular biosynthetic processGO:00313283160.030
anterior posterior pattern specificationGO:00099521360.030
positive regulation of macromolecule metabolic processGO:00106044050.030
positive regulation of cellular amino acid metabolic processGO:004576400.030
gonad developmentGO:0008406500.029
snrna 3 end processingGO:0034472140.029
spermatid differentiationGO:00485151140.029
neurological system processGO:00508773580.028
growthGO:00400073590.028
protein transportGO:00150311550.028
anatomical structure homeostasisGO:0060249970.028
histone modificationGO:00165701060.028
organic substance transportGO:00717022570.028
protein modification processGO:00362114380.027
multi organism behaviorGO:00517051750.027
carbohydrate derivative metabolic processGO:19011352170.026
rna localizationGO:00064031150.026
chromatin organizationGO:00063252070.026
positive regulation of cell communicationGO:00106472500.025
dendrite developmentGO:00163582040.024
protein localizationGO:00081042840.024
positive regulation of developmental processGO:00510941430.023
protein localization to organelleGO:0033365820.023
cellular protein localizationGO:00346131600.023
regulation of bmp signaling pathwayGO:0030510230.023
negative regulation of programmed cell deathGO:0043069720.023
positive regulation of transcription dna templatedGO:00458932660.023
sex differentiationGO:0007548810.023
oocyte microtubule cytoskeleton organizationGO:0016325350.023
mrna metabolic processGO:00160711240.022
positive regulation of catalytic activityGO:00430851180.022
regulation of embryonic developmentGO:0045995680.022
nucleobase containing small molecule metabolic processGO:00550861740.022
intracellular signal transductionGO:00355563000.021
positive regulation of rna metabolic processGO:00512542710.021
chromosome segregationGO:00070591570.021
negative regulation of cellular metabolic processGO:00313243820.021
regulation of protein metabolic processGO:00512462560.021
negative regulation of rna biosynthetic processGO:19026792400.020
macromolecule methylationGO:0043414450.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.020
embryo development ending in birth or egg hatchingGO:00097921520.019
small molecule metabolic processGO:00442813050.019
deathGO:00162652840.019
cellular protein modification processGO:00064644380.019
regulation of cell proliferationGO:00421271630.019
embryonic axis specificationGO:00005781070.019
regulation of developmental growthGO:00486381740.018
cellularizationGO:0007349900.018
peptidyl amino acid modificationGO:00181931050.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
response to woundingGO:0009611940.018
regulation of organelle organizationGO:00330431960.018
negative regulation of rna metabolic processGO:00512532510.018
regulation of apoptotic processGO:00429811300.018
rna interferenceGO:0016246270.017
regulation of cell cycleGO:00517262910.017
innate immune responseGO:00450871440.017
tripartite regional subdivisionGO:00073511030.017
morphogenesis of a branching structureGO:0001763450.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
catabolic processGO:00090564090.017
ribonucleotide metabolic processGO:00092591450.017
segmentationGO:00352822070.017
wound healingGO:0042060750.017
regulation of locomotionGO:0040012420.017
ncrna processingGO:0034470300.017
eye developmentGO:00016543230.016
camera type eye developmentGO:004301040.016
mrna splicing via spliceosomeGO:0000398730.016
regionalizationGO:00030024160.016
single organism catabolic processGO:00447122280.016
regulation of multicellular organismal developmentGO:20000264140.016
regulation of microtubule depolymerizationGO:0031114240.016
regulation of protein localizationGO:0032880760.015
development of primary sexual characteristicsGO:0045137500.015
ribonucleoside metabolic processGO:00091191270.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
nucleocytoplasmic transportGO:0006913720.015
regulation of cellular ketone metabolic processGO:001056530.015
protein complex biogenesisGO:00702712010.015
mrna processingGO:00063971040.015
mitotic sister chromatid segregationGO:0000070870.015
aromatic compound catabolic processGO:00194391660.015
regulation of transportGO:00510491810.015
exocrine system developmentGO:00352721620.015
kidney epithelium developmentGO:007207330.014
taxisGO:00423303040.014
pole plasm assemblyGO:0007315610.014
nuclear pore organizationGO:000699910.014
positive regulation of immune system processGO:0002684680.014
regulation of reproductive processGO:2000241540.014
cellular component assembly involved in morphogenesisGO:00109271510.014
cellular macromolecule localizationGO:00707272200.014
negative regulation of cell deathGO:0060548810.014
salivary gland developmentGO:00074311620.014
kidney developmentGO:000182230.014
reproductive structure developmentGO:0048608740.014
body morphogenesisGO:001017120.014
regulation of response to woundingGO:1903034190.014
agingGO:00075681430.014
germarium derived female germ line cyst formationGO:0030727420.014
positive regulation of phosphate metabolic processGO:00459371390.013
cellular macromolecular complex assemblyGO:00346221530.013
organic cyclic compound catabolic processGO:19013611680.013
positive regulation of multicellular organismal processGO:00512401430.013
organic substance catabolic processGO:19015753080.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
rna splicingGO:0008380830.012
macromolecule catabolic processGO:00090571610.012
rna processingGO:00063961470.012
eye morphogenesisGO:00485922600.012
regulation of protein modification by small protein conjugation or removalGO:1903320250.012
muscle structure developmentGO:00610612240.012
negative regulation of signalingGO:00230572190.012
axis specificationGO:00097981670.012
camera type eye morphogenesisGO:004859320.012
ribose phosphate metabolic processGO:00196931450.011
immune system processGO:00023763470.011
posttranscriptional gene silencingGO:0016441460.011
positive regulation of molecular functionGO:00440931360.011
regulation of mitotic spindle organizationGO:006023690.011
receptor mediated endocytosisGO:0006898210.011
nucleoside phosphate metabolic processGO:00067531620.011
nucleus organizationGO:0006997450.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
positive regulation of signal transductionGO:00099672230.011
regulation of purine nucleotide metabolic processGO:1900542620.011
regulation of neuron projection developmentGO:0010975690.011
response to external biotic stimulusGO:00432072930.011
protein targeting to nucleusGO:0044744510.011
hematopoietic or lymphoid organ developmentGO:0048534570.011
cellular nitrogen compound catabolic processGO:00442701650.011
apoptotic processGO:00069151590.011
nucleobase containing compound catabolic processGO:00346551650.011
programmed cell deathGO:00125012570.011
regulation of neurogenesisGO:00507671580.011
regulation of catalytic activityGO:00507901850.011
photoreceptor cell differentiationGO:00465301700.011
positive regulation of bindingGO:005109940.010
chromatin silencingGO:0006342760.010
positive regulation of cellular amine metabolic processGO:003324000.010
cellular response to dna damage stimulusGO:00069742230.010

pcm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
sensory system diseaseDOID:005015500.010