Drosophila melanogaster

107 known processes

l(1)sc (Dmel_CG3839)

lethal of scute

(Aliases: bHLHc28,CG3839,L(1)sc,L'Sc,l'sc,l(1)1Ba,lsc,ASC-T3,T3,L'sc,ascT3,sc/T3,AS-C T3,Dmel\CG3839,EG:198A6.2,l-sc,AS-T3)

l(1)sc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tube morphogenesisGO:00352391910.174
negative regulation of gene expressionGO:00106293870.170
Human Zebrafish
negative regulation of rna biosynthetic processGO:19026792400.160
Human
negative regulation of macromolecule biosynthetic processGO:00105582700.151
Human
negative regulation of nitrogen compound metabolic processGO:00511722650.147
Human
tube developmentGO:00352952440.127
single organism behaviorGO:00447083910.123
epithelial cell differentiationGO:00308553220.102
Zebrafish Mouse
tissue morphogenesisGO:00487292970.100
negative regulation of biosynthetic processGO:00098902770.098
Human
negative regulation of cellular metabolic processGO:00313243820.097
Human
response to abiotic stimulusGO:00096283410.090
Human
regulation of growthGO:00400082330.088
Worm
negative regulation of nucleic acid templated transcriptionGO:19035072400.088
Human
epithelial cell developmentGO:00020642740.088
Zebrafish
negative regulation of nucleobase containing compound metabolic processGO:00459342610.088
Human
negative regulation of cellular biosynthetic processGO:00313272770.080
Human
body morphogenesisGO:001017120.079
Worm
notch signaling pathwayGO:00072191200.078
Human Mouse
digestive system developmentGO:00551231490.077
telencephalon developmentGO:002153720.076
Mouse
negative regulation of transcription dna templatedGO:00458922370.075
Human
transcription from rna polymerase ii promoterGO:00063663680.074
regulation of behaviorGO:0050795750.074
Worm
regionalizationGO:00030024160.073
Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.070
negative regulation of rna metabolic processGO:00512532510.069
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.066
brain developmentGO:00074201200.066
Human Zebrafish Mouse
regulation of multicellular organismal developmentGO:20000264140.065
Human Mouse Rat Worm
forebrain developmentGO:003090020.064
Human Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.064
Human
multi organism behaviorGO:00517051750.063
Worm
central nervous system developmentGO:00074172010.062
Human Zebrafish Mouse
gland developmentGO:00487321910.061
Zebrafish Mouse
cell fate specificationGO:0001708710.060
Mouse Worm
columnar cuboidal epithelial cell differentiationGO:00020652560.060
Mouse
multi organism reproductive behaviorGO:00447051210.059
Worm
developmental growthGO:00485892800.056
Zebrafish Worm
regulation of cell sizeGO:0008361630.055
Worm
localization of cellGO:00516742570.055
Mouse Worm
epithelial tube morphogenesisGO:0060562880.052
growthGO:00400073590.052
Zebrafish Worm
segmentationGO:00352822070.051
multicellular organismal reproductive behaviorGO:00330571100.050
Worm
positive regulation of signal transductionGO:00099672230.049
Mouse
neural precursor cell proliferationGO:0061351750.049
Mouse
response to organic substanceGO:00100332840.048
Human
positive regulation of rna biosynthetic processGO:19026802660.048
organelle fissionGO:00482853400.047
Fly
regulation of gene expression epigeneticGO:00400291280.047
nuclear divisionGO:00002803320.046
Fly
embryonic morphogenesisGO:00485982060.046
positive regulation of response to stimulusGO:00485843230.045
Mouse
hindbrain developmentGO:003090220.045
Zebrafish Mouse
regulation of organelle organizationGO:00330431960.045
Fly
respiratory system developmentGO:00605412130.045
Mouse
digestive tract developmentGO:00485651490.044
mitotic nuclear divisionGO:00070672130.043
Fly
salivary gland developmentGO:00074311620.043
taxisGO:00423303040.043
Worm
sensory organ morphogenesisGO:00905962600.043
Zebrafish
positive regulation of nitrogen compound metabolic processGO:00511733540.042
positive regulation of biosynthetic processGO:00098913160.042
regulation of mitotic cell cycleGO:00073461900.042
Mouse Fly
head developmentGO:00603221350.041
Human Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.040
dna metabolic processGO:00062592270.040
chaeta developmentGO:0022416970.040
Fly
regulation of axon extension involved in axon guidanceGO:004884140.039
Worm
regulation of response to external stimulusGO:00321011150.039
Worm Fly
regulation of cell morphogenesisGO:00226041630.039
Worm
regulation of developmental growthGO:00486381740.038
Worm
regulation of cell developmentGO:00602842150.038
Human Mouse Rat Worm
compound eye developmentGO:00487493070.038
regulation of nervous system developmentGO:00519602480.037
Human Mouse Rat Worm
regulation of cellular component sizeGO:0032535980.036
Worm
positive regulation of gene expressionGO:00106282900.036
renal tubule developmentGO:0061326640.035
axon developmentGO:00615642970.035
Worm
positive regulation of cellular biosynthetic processGO:00313283160.034
neuron projection guidanceGO:00974852410.034
Worm
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.034
Human
compound eye morphogenesisGO:00017452490.034
positive regulation of signalingGO:00230562430.034
Mouse
negative regulation of cell cycleGO:00457861160.034
Fly
response to oxygen containing compoundGO:19017002000.033
Human
negative regulation of developmental processGO:00510932010.033
Human Mouse Rat
dorsal ventral pattern formationGO:00099531330.032
Mouse
positive regulation of rna metabolic processGO:00512542710.032
exocrine system developmentGO:00352721620.031
regulation of notch signaling pathwayGO:00085931000.031
Mouse
morphogenesis of an epitheliumGO:00020092760.031
eye developmentGO:00016543230.031
mesoderm developmentGO:0007498780.031
chromosome organizationGO:00512763600.031
salivary gland morphogenesisGO:00074351450.031
organonitrogen compound metabolic processGO:19015643180.030
Fly
locomotory behaviorGO:00076261760.030
eye morphogenesisGO:00485922600.030
regulation of reproductive processGO:2000241540.030
Worm
response to external biotic stimulusGO:00432072930.030
Fly
regulation of localizationGO:00328792750.029
Worm
homeostatic processGO:00425921990.029
axonogenesisGO:00074092900.028
Worm
small molecule metabolic processGO:00442813050.028
cell divisionGO:00513012480.028
Worm Fly
wound healingGO:0042060750.028
Zebrafish
regulation of axonogenesisGO:0050770320.028
Worm
negative regulation of mitotic cell cycleGO:00459301090.028
Fly
malpighian tubule morphogenesisGO:0007443440.028
regulation of cell cycle processGO:00105641810.027
Fly
imaginal disc derived wing morphogenesisGO:00074763370.027
camera type eye developmentGO:004301040.027
deathGO:00162652840.027
Human Mouse Worm Fly
cell motilityGO:00488702510.027
Mouse Worm
regulation of neural precursor cell proliferationGO:2000177350.026
Mouse
negative regulation of response to stimulusGO:00485852580.026
segment specificationGO:0007379330.026
cell proliferationGO:00082832990.026
phosphorylationGO:00163102940.026
developmental maturationGO:00217001720.025
Zebrafish Mouse
regulation of cell differentiationGO:00455953020.025
Human Mouse Rat Worm
photoreceptor cell differentiationGO:00465301700.025
multi multicellular organism processGO:00447061230.025
Worm
negative regulation of multicellular organismal processGO:00512411420.025
Human Rat
stem cell proliferationGO:0072089880.025
Mouse
spinal cord developmentGO:002151010.025
Mouse
embryonic pattern specificationGO:00098801740.024
blastoderm segmentationGO:00073501590.024
cellular macromolecular complex assemblyGO:00346221530.024
regulation of neurogenesisGO:00507671580.024
Human Mouse Rat Worm
single organism cellular localizationGO:19025801800.024
positive regulation of nucleic acid templated transcriptionGO:19035082660.024
regulation of cell cycleGO:00517262910.024
Mouse Fly
regulation of anatomical structure morphogenesisGO:00226032420.024
Worm
regulation of anatomical structure sizeGO:00900661630.024
Worm
intracellular signal transductionGO:00355563000.023
positive regulation of transcription dna templatedGO:00458932660.023
cell growthGO:00160491080.023
Worm
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.023
gastrulationGO:0007369700.023
gene silencingGO:00164581380.023
gland morphogenesisGO:00226121450.023
imaginal disc pattern formationGO:0007447910.023
stem cell developmentGO:0048864790.022
Mouse
macromolecular complex assemblyGO:00650032560.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
cell deathGO:00082192790.022
Human Mouse Worm Fly
appendage developmentGO:00487364010.022
response to woundingGO:0009611940.022
Zebrafish
nephron developmentGO:007200630.022
chaeta morphogenesisGO:0008407420.022
Fly
compound eye photoreceptor cell differentiationGO:00017511400.021
connective tissue developmentGO:006144830.021
positive regulation of developmental processGO:00510941430.021
Mouse
cell fate determinationGO:0001709910.021
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.021
negative regulation of programmed cell deathGO:0043069720.021
Human Fly
regulation of intracellular signal transductionGO:19025312360.021
regulation of mitosisGO:0007088560.021
Fly
enzyme linked receptor protein signaling pathwayGO:00071671790.021
imaginal disc derived appendage developmentGO:00487373990.020
positive regulation of cell communicationGO:00106472500.020
Mouse
nephron epithelium developmentGO:007200930.020
neuron fate commitmentGO:0048663500.020
Human Mouse
regulation of ovipositionGO:0046662140.020
Worm
response to biotic stimulusGO:00096072940.020
Fly
regulation of neuron differentiationGO:00456641030.020
Human Mouse Worm
negative regulation of signal transductionGO:00099682060.020
protein modification processGO:00362114380.019
cellular protein modification processGO:00064644380.019
intracellular transportGO:00469072280.019
regulation of cell morphogenesis involved in differentiationGO:0010769610.019
Worm
positive regulation of multicellular organismal processGO:00512401430.019
Mouse
post embryonic appendage morphogenesisGO:00351203850.019
chromatin modificationGO:00165681470.019
mesenchymal cell developmentGO:001403110.019
reproductive behaviorGO:00190981220.019
Worm
regulation of programmed cell deathGO:00430671520.019
Human Mouse Worm Fly
regulation of response to stressGO:00801342000.019
positive regulation of growthGO:0045927750.019
Worm
immune effector processGO:0002252980.019
Fly
negative regulation of cellular component organizationGO:00511291080.018
Fly
adult behaviorGO:00305341370.018
sex determinationGO:0007530180.018
Fly
anterior posterior pattern specificationGO:00099521360.018
negative regulation of cell cycle processGO:00109481090.018
Fly
eye photoreceptor cell differentiationGO:00017541450.018
regulation of immune responseGO:00507761180.018
Fly
regulation of epithelial cell differentiationGO:003085640.018
Mouse
ameboidal type cell migrationGO:00016671510.018
response to decreased oxygen levelsGO:0036293580.018
Human
immune responseGO:00069552460.018
Fly
organic acid metabolic processGO:00060821030.018
malpighian tubule developmentGO:0072002640.018
larval developmentGO:00021641040.018
Worm
vesicle mediated transportGO:00161923810.018
neuron projection extensionGO:1990138320.017
Worm
ovarian follicle cell developmentGO:00307072480.017
carboxylic acid metabolic processGO:0019752920.017
neuroepithelial cell differentiationGO:006056360.017
Mouse
multicellular organismal agingGO:00102591400.017
regulation of immune effector processGO:0002697520.017
Fly
chemotaxisGO:00069352490.017
Worm
regulation of locomotionGO:0040012420.017
Worm
stem cell fate commitmentGO:0048865250.017
Mouse Worm
catabolic processGO:00090564090.017
regulation of cell proliferationGO:00421271630.017
Mouse Rat
hindgut developmentGO:0061525580.017
mesenchymal cell differentiationGO:004876210.017
renal system developmentGO:0072001720.017
apoptotic processGO:00069151590.017
Human Mouse Fly
cell adhesionGO:00071551360.017
dendrite morphogenesisGO:00488131990.017
positive regulation of intracellular signal transductionGO:19025331160.017
wing disc pattern formationGO:0035222660.016
retina development in camera type eyeGO:006004140.016
hindgut morphogenesisGO:0007442580.016
peptide metabolic processGO:0006518800.016
Fly
regulation of phosphorus metabolic processGO:00511742100.016
negative regulation of cell differentiationGO:00455961430.016
Human Mouse Rat
single organism biosynthetic processGO:00447112060.016
positive regulation of cell cycleGO:0045787430.016
Mouse
regulation of apoptotic processGO:00429811300.016
Human Mouse Fly
establishment of localization in cellGO:00516494020.016
organic substance transportGO:00717022570.015
cellular response to dna damage stimulusGO:00069742230.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.015
negative regulation of cell communicationGO:00106482230.015
oxoacid metabolic processGO:00434361030.015
organic substance catabolic processGO:19015753080.015
response to temperature stimulusGO:00092661060.015
phagocytosisGO:00069092150.015
gliogenesisGO:0042063800.015
Mouse Rat
regulation of antimicrobial humoral responseGO:0002759500.015
Fly
humoral immune responseGO:00069591170.015
Fly
cellular amide metabolic processGO:0043603800.015
Fly
positive regulation of notch signaling pathwayGO:0045747340.015
Mouse
peptide biosynthetic processGO:0043043420.015
Fly
negative regulation of signalingGO:00230572190.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
cellular response to chemical stimulusGO:00708871990.015
peripheral nervous system developmentGO:0007422520.015
Fly
antimicrobial humoral responseGO:0019730990.015
Fly
appendage morphogenesisGO:00351073970.015
programmed cell deathGO:00125012570.015
Human Mouse Worm Fly
developmental cell growthGO:0048588520.015
Worm
embryonic development via the syncytial blastodermGO:00017001480.014
negative regulation of cell developmentGO:0010721620.014
Human Rat
negative regulation of organelle organizationGO:0010639560.014
Fly
anatomical structure homeostasisGO:0060249970.014
regulation of cellular ketone metabolic processGO:001056530.014
renal tubule morphogenesisGO:0061333440.014
axon guidanceGO:00074112330.014
Worm
sensory perception of mechanical stimulusGO:0050954720.014
camera type eye morphogenesisGO:004859320.014
positive regulation of neuron apoptotic processGO:004352510.014
Mouse
single organism intracellular transportGO:19025822070.014
response to lipopolysaccharideGO:003249640.014
cellular catabolic processGO:00442483720.013
neuroblast proliferationGO:0007405740.013
Mouse
response to other organismGO:00517072930.013
Fly
regulation of nuclear divisionGO:0051783580.013
Fly
cell type specific apoptotic processGO:0097285380.013
Mouse
dorsal ventral pattern formation imaginal discGO:0007450510.013
sensory organ boundary specificationGO:0008052220.013
locomotor rhythmGO:0045475560.013
positive regulation of cell differentiationGO:0045597640.013
Mouse
gastrulation involving germ band extensionGO:0010004360.013
hematopoietic progenitor cell differentiationGO:000224410.013
wing disc morphogenesisGO:00074723440.013
cellular amine metabolic processGO:0044106120.013
carbohydrate derivative metabolic processGO:19011352170.013
gastrulation with mouth forming firstGO:0001703360.013
response to heatGO:0009408630.013
cellular ketone metabolic processGO:0042180240.013
cell migrationGO:00164772380.013
Mouse Worm
cellular amino acid metabolic processGO:0006520610.013
dendrite developmentGO:00163582040.013
formation of organ boundaryGO:0010160300.013
regulation of production of molecular mediator of immune responseGO:0002700440.013
Fly
digestive tract morphogenesisGO:00485461270.012
detection of external stimulusGO:0009581660.012
eggshell formationGO:00307031050.012
neurological system processGO:00508773580.012
kidney developmentGO:000182230.012
glycosyl compound metabolic processGO:19016571270.012
sensory organ precursor cell fate determinationGO:0016360190.012
sensory perception of painGO:001923340.012
muscle structure developmentGO:00610612240.012
regulation of cellular amine metabolic processGO:003323830.012
embryonic axis specificationGO:00005781070.012
establishment or maintenance of cell polarityGO:00071631670.012
regulation of cell deathGO:00109411730.012
Human Mouse Worm Fly
glial cell differentiationGO:0010001350.012
Mouse
negative regulation of gene expression epigeneticGO:0045814770.012
lipid metabolic processGO:00066291210.012
larval behaviorGO:0030537420.012
spindle organizationGO:00070512530.012
organophosphate metabolic processGO:00196371950.012
embryonic hindgut morphogenesisGO:0048619480.011
regulation of immune system processGO:00026821760.011
Fly
rna processingGO:00063961470.011
determination of adult lifespanGO:00083401370.011
negative regulation of growthGO:0045926840.011
chromatin silencingGO:0006342760.011
cell maturationGO:00484691440.011
Zebrafish Mouse
regulation of stem cell proliferationGO:0072091400.011
amine metabolic processGO:0009308120.011
organelle localizationGO:00516401480.011
regulation of cellular amino acid metabolic processGO:000652100.011
organonitrogen compound biosynthetic processGO:19015661170.011
Fly
cranial nerve developmentGO:002154510.011
cellular response to molecule of bacterial originGO:007121930.011
embryo development ending in birth or egg hatchingGO:00097921520.011
Human Mouse
axis specificationGO:00097981670.011
antimicrobial peptide biosynthetic processGO:0002777380.011
Fly
histolysisGO:00075591020.011
covalent chromatin modificationGO:00165691060.011
protein complex assemblyGO:00064612000.011
cytoplasmic transportGO:00164821300.011
endocytosisGO:00068973100.011
mrna processingGO:00063971040.011
regulation of epidermal cell differentiationGO:004560430.011
protein localizationGO:00081042840.011
nephron tubule developmentGO:007208030.011
positive regulation of catalytic activityGO:00430851180.011
regulation of cellular component movementGO:0051270420.011
Worm
salivary gland histolysisGO:0035070880.011
chitin based cuticle developmentGO:0040003490.010
regulation of neuron projection developmentGO:0010975690.010
Worm
cardiovascular system developmentGO:0072358820.010
urogenital system developmentGO:0001655720.010
negative regulation of notch signaling pathwayGO:0045746410.010
developmental programmed cell deathGO:00106231380.010
regulation of cellular protein metabolic processGO:00322682430.010
actin filament based processGO:00300292200.010
vitamin metabolic processGO:000676620.010
positive regulation of cellular component organizationGO:00511301560.010
dna conformation changeGO:00711031050.010

l(1)sc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.026
disease of metabolismDOID:001466700.015
connective tissue diseaseDOID:6500.015
nervous system diseaseDOID:86300.011
kidney diseaseDOID:55700.011
renal tubular transport diseaseDOID:44700.011
urinary system diseaseDOID:1800.011