IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG8446 (Dmel_CG8446)

CG8446 gene product from transcript CG8446-RC

(Aliases: Dmel\CG8446)

Entrez: 36795
FLYBASE: FBgn0034089
UniProtKB: Q8SX78

Process Predictions
Disease Predictions

CG8446 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
organonitrogen compound metabolic process	GO:1901564	318	0.256
organic acid metabolic process	GO:0006082	103	0.240
carboxylic acid metabolic process	GO:0019752	92	0.210
small molecule metabolic process	GO:0044281	305	0.168
oxoacid metabolic process	GO:0043436	103	0.168
nucleotide metabolic process	GO:0009117	161	0.127
single organism biosynthetic process	GO:0044711	206	0.102
organophosphate metabolic process	GO:0019637	195	0.091
single organism catabolic process	GO:0044712	228	0.088
vesicle mediated transport	GO:0016192	381	0.065
alpha amino acid metabolic process	GO:1901605	20	0.064
intracellular transport	GO:0046907	228	0.063
response to organic substance	GO:0010033	284	0.061
organonitrogen compound catabolic process	GO:1901565	128	0.061
carbohydrate derivative metabolic process	GO:1901135	217	0.055
response to oxygen containing compound	GO:1901700	200	0.054
regulation of cellular ketone metabolic process	GO:0010565	3	0.050
negative regulation of biosynthetic process	GO:0009890	277	0.047
eye development	GO:0001654	323	0.045
protein modification process	GO:0036211	438	0.044
positive regulation of cell communication	GO:0010647	250	0.043
nucleoside phosphate metabolic process	GO:0006753	162	0.043
negative regulation of rna biosynthetic process	GO:1902679	240	0.042
negative regulation of cellular biosynthetic process	GO:0031327	277	0.041
organic substance catabolic process	GO:1901575	308	0.041
establishment of localization in cell	GO:0051649	402	0.038
catabolic process	GO:0009056	409	0.037
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.036
cellular amino acid metabolic process	GO:0006520	61	0.036
positive regulation of signaling	GO:0023056	243	0.035
wnt signaling pathway	GO:0016055	98	0.035
negative regulation of rna metabolic process	GO:0051253	251	0.034
organic substance transport	GO:0071702	257	0.033
carbohydrate biosynthetic process	GO:0016051	17	0.033
imaginal disc pattern formation	GO:0007447	91	0.032
imaginal disc derived wing morphogenesis	GO:0007476	337	0.032
carbohydrate metabolic process	GO:0005975	82	0.032
negative regulation of gene expression	GO:0010629	387	0.031
cellular protein localization	GO:0034613	160	0.030
cellular response to inorganic substance	GO:0071241	8	0.030
protein complex biogenesis	GO:0070271	201	0.029
cell proliferation	GO:0008283	299	0.029
cellular protein modification process	GO:0006464	438	0.028
nucleobase containing small molecule metabolic process	GO:0055086	174	0.028
protein transport	GO:0015031	155	0.028
tube development	GO:0035295	244	0.027
mitotic spindle organization	GO:0007052	220	0.027
protein complex assembly	GO:0006461	200	0.027
single organism intracellular transport	GO:1902582	207	0.027
cellular response to chemical stimulus	GO:0070887	199	0.027
cellular macromolecule localization	GO:0070727	220	0.027
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.026
appendage development	GO:0048736	401	0.026
ion transport	GO:0006811	145	0.025
spindle organization	GO:0007051	253	0.024
response to alcohol	GO:0097305	95	0.024
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.024
chromatin silencing	GO:0006342	76	0.024
epithelial cell differentiation	GO:0030855	322	0.024
dorsal ventral pattern formation	GO:0009953	133	0.023
chemical homeostasis	GO:0048878	92	0.023
protein localization	GO:0008104	284	0.023
pigmentation	GO:0043473	75	0.023
gland development	GO:0048732	191	0.023
regulation of organelle organization	GO:0033043	196	0.023
detection of chemical stimulus	GO:0009593	93	0.023
proteolysis	GO:0006508	192	0.022
response to lipopolysaccharide	GO:0032496	4	0.022
embryo development ending in birth or egg hatching	GO:0009792	152	0.022
ribonucleotide metabolic process	GO:0009259	145	0.022
cell projection assembly	GO:0030031	94	0.022
single organism carbohydrate metabolic process	GO:0044723	72	0.021
glycosyl compound metabolic process	GO:1901657	127	0.021
regulation of wnt signaling pathway	GO:0030111	68	0.021
gene silencing	GO:0016458	138	0.021
response to endogenous stimulus	GO:0009719	119	0.020
microtubule organizing center organization	GO:0031023	168	0.020
response to reactive oxygen species	GO:0000302	24	0.020
digestive system development	GO:0055123	149	0.019
macromolecular complex assembly	GO:0065003	256	0.019
centrosome organization	GO:0051297	163	0.019
endocytosis	GO:0006897	310	0.019
phosphorylation	GO:0016310	294	0.019
establishment of protein localization	GO:0045184	163	0.019
body morphogenesis	GO:0010171	2	0.019
small molecule biosynthetic process	GO:0044283	37	0.019
regulation of cellular protein metabolic process	GO:0032268	243	0.019
cellular catabolic process	GO:0044248	372	0.019
appendage morphogenesis	GO:0035107	397	0.018
cellular response to metal ion	GO:0071248	6	0.018
organelle fission	GO:0048285	340	0.018
actin cytoskeleton organization	GO:0030036	206	0.018
post embryonic appendage morphogenesis	GO:0035120	385	0.018
regulation of cell cycle	GO:0051726	291	0.018
phagocytosis	GO:0006909	215	0.018
cell death	GO:0008219	279	0.018
g protein coupled receptor signaling pathway	GO:0007186	136	0.018
purine nucleotide metabolic process	GO:0006163	146	0.018
cellular response to growth factor stimulus	GO:0071363	30	0.017
regulation of protein modification process	GO:0031399	112	0.017
cellular response to dna damage stimulus	GO:0006974	223	0.017
cellular carbohydrate metabolic process	GO:0044262	22	0.017
growth	GO:0040007	359	0.017
cell division	GO:0051301	248	0.017
protein targeting	GO:0006605	64	0.017
compound eye morphogenesis	GO:0001745	249	0.017
single organism cellular localization	GO:1902580	180	0.017
tissue morphogenesis	GO:0048729	297	0.016
lateral inhibition	GO:0046331	206	0.016
forebrain development	GO:0030900	2	0.016
positive regulation of signal transduction	GO:0009967	223	0.016
telencephalon development	GO:0021537	2	0.016
small molecule catabolic process	GO:0044282	21	0.016
embryonic development via the syncytial blastoderm	GO:0001700	148	0.016
regulation of cell proliferation	GO:0042127	163	0.016
negative regulation of transcription dna templated	GO:0045892	237	0.016
acyl coa metabolic process	GO:0006637	3	0.016
cell motility	GO:0048870	251	0.016
cellular response to reactive oxygen species	GO:0034614	14	0.015
spermatid development	GO:0007286	98	0.015
embryonic morphogenesis	GO:0048598	206	0.015
mrna processing	GO:0006397	104	0.015
autophagic cell death	GO:0048102	83	0.015
cellular response to oxygen containing compound	GO:1901701	79	0.015
cellular homeostasis	GO:0019725	80	0.015
cellular response to organic substance	GO:0071310	132	0.015
regulation of steroid metabolic process	GO:0019218	2	0.015
cell cell junction organization	GO:0045216	55	0.015
thioester metabolic process	GO:0035383	3	0.015
regulation of protein metabolic process	GO:0051246	256	0.015
response to nitrogen compound	GO:1901698	90	0.015
organic acid biosynthetic process	GO:0016053	15	0.014
multicellular organismal aging	GO:0010259	140	0.014
wing disc pattern formation	GO:0035222	66	0.014
positive regulation of cellular catabolic process	GO:0031331	95	0.014
actin filament based process	GO:0030029	220	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.014
secretion by cell	GO:0032940	101	0.014
membrane organization	GO:0061024	112	0.014
positive regulation of cell death	GO:0010942	69	0.014
negative regulation of developmental process	GO:0051093	201	0.013
negative regulation of cellular metabolic process	GO:0031324	382	0.013
purine ribonucleotide metabolic process	GO:0009150	145	0.013
cell maturation	GO:0048469	144	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013
death	GO:0016265	284	0.013
response to hexose	GO:0009746	3	0.013
kidney development	GO:0001822	3	0.013
cellular response to endogenous stimulus	GO:0071495	80	0.013
positive regulation of response to stimulus	GO:0048584	323	0.013
developmental maturation	GO:0021700	172	0.013
ribose phosphate metabolic process	GO:0019693	145	0.013
response to radiation	GO:0009314	155	0.012
cellular response to peptide hormone stimulus	GO:0071375	28	0.012
regulation of growth	GO:0040008	233	0.012
monocarboxylic acid metabolic process	GO:0032787	29	0.012
regulation of organ morphogenesis	GO:2000027	78	0.012
response to ethanol	GO:0045471	59	0.012
eye morphogenesis	GO:0048592	260	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.012
compound eye development	GO:0048749	307	0.012
protein localization to organelle	GO:0033365	82	0.012
cellular response to mechanical stimulus	GO:0071260	2	0.012
carbohydrate derivative catabolic process	GO:1901136	118	0.012
thiosulfate transport	GO:0015709	2	0.012
positive regulation of cell motility	GO:2000147	3	0.012
cellular response to external stimulus	GO:0071496	66	0.012
carboxylic acid biosynthetic process	GO:0046394	15	0.012
negative regulation of gene expression epigenetic	GO:0045814	77	0.012
nucleoside metabolic process	GO:0009116	127	0.012
cellular response to hormone stimulus	GO:0032870	44	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
apoptotic process	GO:0006915	159	0.011
mitotic nuclear division	GO:0007067	213	0.011
rna processing	GO:0006396	147	0.011
centrosome cycle	GO:0007098	137	0.011
cytoplasmic transport	GO:0016482	130	0.011
developmental growth	GO:0048589	280	0.011
positive regulation of cellular biosynthetic process	GO:0031328	316	0.011
regulation of cellular amine metabolic process	GO:0033238	3	0.011
epidermis development	GO:0008544	65	0.011
actin filament organization	GO:0007015	126	0.011
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
chaeta development	GO:0022416	97	0.011
regulation of multicellular organismal development	GO:2000026	414	0.011
digestive tract development	GO:0048565	149	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
cellular macromolecule catabolic process	GO:0044265	136	0.011
energy derivation by oxidation of organic compounds	GO:0015980	32	0.011
chromosome organization	GO:0051276	360	0.011
oxidation reduction process	GO:0055114	123	0.011
muscle structure development	GO:0061061	224	0.010
regionalization	GO:0003002	416	0.010
gtp catabolic process	GO:0006184	72	0.010
posttranscriptional regulation of gene expression	GO:0010608	145	0.010
sulfur compound metabolic process	GO:0006790	59	0.010
imaginal disc derived appendage development	GO:0048737	399	0.010
regulation of protein stability	GO:0031647	43	0.010
camera type eye development	GO:0043010	4	0.010
centrosome duplication	GO:0051298	121	0.010

CG8446 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of metabolism	DOID:0014667	0	0.021
	inherited metabolic disorder	DOID:655	0	0.011

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