IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12877 (Dmel_CG12877)

CG12877 gene product from transcript CG12877-RC

(Aliases: Dmel\CG12877,BcDNA:LD30051)

Entrez: 43333
FLYBASE: FBgn0039544
UniProtKB: Q2PDP6

Process Predictions
Disease Predictions

CG12877 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
dna metabolic process	GO:0006259	227	0.120
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.084
body morphogenesis	GO:0010171	2	0.077
negative regulation of cellular metabolic process	GO:0031324	382	0.075
catabolic process	GO:0009056	409	0.073
growth	GO:0040007	359	0.072
programmed cell death	GO:0012501	257	0.066
regulation of intracellular signal transduction	GO:1902531	236	0.065
positive regulation of transcription dna templated	GO:0045893	266	0.062
negative regulation of gene expression	GO:0010629	387	0.059
cellular catabolic process	GO:0044248	372	0.057
apoptotic process	GO:0006915	159	0.057
regulation of multi organism process	GO:0043900	131	0.056
intracellular signal transduction	GO:0035556	300	0.054
nucleotide metabolic process	GO:0009117	161	0.053
positive regulation of response to stimulus	GO:0048584	323	0.053
cellular response to dna damage stimulus	GO:0006974	223	0.052
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.051
negative regulation of cell cycle process	GO:0010948	109	0.050
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.050
death	GO:0016265	284	0.049
positive regulation of biosynthetic process	GO:0009891	316	0.048
protein modification process	GO:0036211	438	0.048
multicellular organismal aging	GO:0010259	140	0.046
response to abiotic stimulus	GO:0009628	341	0.043
purine nucleoside catabolic process	GO:0006152	112	0.043
phosphorylation	GO:0016310	294	0.042
negative regulation of cell cycle phase transition	GO:1901988	103	0.041
positive regulation of rna biosynthetic process	GO:1902680	266	0.041
regulation of localization	GO:0032879	275	0.040
organonitrogen compound metabolic process	GO:1901564	318	0.039
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.039
regulation of molecular function	GO:0065009	217	0.039
spermatid development	GO:0007286	98	0.037
cell death	GO:0008219	279	0.037
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.037
organophosphate metabolic process	GO:0019637	195	0.036
developmental growth	GO:0048589	280	0.036
negative regulation of biosynthetic process	GO:0009890	277	0.036
embryo development ending in birth or egg hatching	GO:0009792	152	0.035
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.035
single organism catabolic process	GO:0044712	228	0.035
negative regulation of cellular biosynthetic process	GO:0031327	277	0.034
protein localization	GO:0008104	284	0.034
chromosome organization	GO:0051276	360	0.034
biological adhesion	GO:0022610	138	0.034
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.034
organelle fission	GO:0048285	340	0.034
nuclear division	GO:0000280	332	0.033
spermatogenesis	GO:0007283	200	0.033
positive regulation of phosphate metabolic process	GO:0045937	139	0.033
positive regulation of signal transduction	GO:0009967	223	0.032
organic substance catabolic process	GO:1901575	308	0.032
regulation of programmed cell death	GO:0043067	152	0.031
response to external biotic stimulus	GO:0043207	293	0.030
positive regulation of macromolecule metabolic process	GO:0010604	405	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.030
regulation of response to stress	GO:0080134	200	0.030
dna repair	GO:0006281	54	0.030
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.030
ribose phosphate metabolic process	GO:0019693	145	0.029
organonitrogen compound catabolic process	GO:1901565	128	0.029
negative regulation of signaling	GO:0023057	219	0.029
aging	GO:0007568	143	0.028
ovarian follicle cell development	GO:0030707	248	0.028
regulation of phosphate metabolic process	GO:0019220	210	0.028
single organism biosynthetic process	GO:0044711	206	0.028
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.028
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.028
nucleoside phosphate metabolic process	GO:0006753	162	0.028
purine nucleotide metabolic process	GO:0006163	146	0.028
cellular protein modification process	GO:0006464	438	0.028
columnar cuboidal epithelial cell development	GO:0002066	249	0.027
purine ribonucleotide catabolic process	GO:0009154	109	0.027
double strand break repair	GO:0006302	26	0.027
organonitrogen compound biosynthetic process	GO:1901566	117	0.027
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.027
positive regulation of cellular biosynthetic process	GO:0031328	316	0.027
cell cycle checkpoint	GO:0000075	95	0.026
regulation of cell death	GO:0010941	173	0.026
regulation of cell cycle phase transition	GO:1901987	130	0.026
regulation of catalytic activity	GO:0050790	185	0.026
negative regulation of rna biosynthetic process	GO:1902679	240	0.026
cell migration	GO:0016477	238	0.026
positive regulation of gene expression	GO:0010628	290	0.026
forebrain development	GO:0030900	2	0.026
cell motility	GO:0048870	251	0.025
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.025
cellular amino acid metabolic process	GO:0006520	61	0.025
organic cyclic compound catabolic process	GO:1901361	168	0.025
mapk cascade	GO:0000165	107	0.025
ras protein signal transduction	GO:0007265	88	0.024
negative regulation of transcription dna templated	GO:0045892	237	0.024
response to radiation	GO:0009314	155	0.024
nucleoside triphosphate metabolic process	GO:0009141	120	0.024
nucleobase containing small molecule metabolic process	GO:0055086	174	0.024
intracellular transport	GO:0046907	228	0.024
purine ribonucleotide metabolic process	GO:0009150	145	0.024
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.024
regulation of apoptotic process	GO:0042981	130	0.024
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.023
single organism intracellular transport	GO:1902582	207	0.023
gene silencing	GO:0016458	138	0.023
negative regulation of response to stimulus	GO:0048585	258	0.023
determination of adult lifespan	GO:0008340	137	0.023
small molecule metabolic process	GO:0044281	305	0.023
carbohydrate derivative catabolic process	GO:1901136	118	0.023
negative regulation of cell communication	GO:0010648	223	0.023
negative regulation of mitotic cell cycle	GO:0045930	109	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.022
carbohydrate derivative metabolic process	GO:1901135	217	0.022
secretion	GO:0046903	109	0.022
nucleobase containing compound catabolic process	GO:0034655	165	0.022
membrane organization	GO:0061024	112	0.021
anterior posterior pattern specification	GO:0009952	136	0.021
purine ribonucleoside catabolic process	GO:0046130	112	0.021
purine nucleoside metabolic process	GO:0042278	127	0.021
cell cycle phase transition	GO:0044770	140	0.021
chromosome segregation	GO:0007059	157	0.021
glycosyl compound metabolic process	GO:1901657	127	0.021
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.021
cell adhesion	GO:0007155	136	0.021
cellular nitrogen compound catabolic process	GO:0044270	165	0.020
positive regulation of phosphorus metabolic process	GO:0010562	139	0.020
heterocycle catabolic process	GO:0046700	166	0.020
peptidyl amino acid modification	GO:0018193	105	0.020
ribonucleoside catabolic process	GO:0042454	112	0.020
transcription from rna polymerase ii promoter	GO:0006366	368	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
positive regulation of rna metabolic process	GO:0051254	271	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
small gtpase mediated signal transduction	GO:0007264	88	0.020
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.020
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.020
negative regulation of cell cycle	GO:0045786	116	0.020
cytoplasmic transport	GO:0016482	130	0.020
proteolysis	GO:0006508	192	0.020
regulation of mapk cascade	GO:0043408	92	0.020
organophosphate catabolic process	GO:0046434	112	0.020
signal transduction by phosphorylation	GO:0023014	107	0.020
single organism behavior	GO:0044708	391	0.019
mitotic cell cycle phase transition	GO:0044772	138	0.019
ribonucleoside metabolic process	GO:0009119	127	0.019
nucleoside triphosphate catabolic process	GO:0009143	108	0.019
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.019
cell proliferation	GO:0008283	299	0.019
cellular protein localization	GO:0034613	160	0.019
response to biotic stimulus	GO:0009607	294	0.019
nucleoside metabolic process	GO:0009116	127	0.019
regulation of cell cycle	GO:0051726	291	0.019
regionalization	GO:0003002	416	0.018
segmentation	GO:0035282	207	0.018
mitotic cell cycle checkpoint	GO:0007093	88	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
purine containing compound metabolic process	GO:0072521	155	0.018
ribonucleotide metabolic process	GO:0009259	145	0.018
purine ribonucleoside metabolic process	GO:0046128	127	0.018
mitotic sister chromatid segregation	GO:0000070	87	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.018
oxoacid metabolic process	GO:0043436	103	0.018
regulation of mrna splicing via spliceosome	GO:0048024	64	0.017
regulation of catabolic process	GO:0009894	170	0.017
organic substance transport	GO:0071702	257	0.017
cellular amide metabolic process	GO:0043603	80	0.017
anterior posterior axis specification	GO:0009948	109	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
regulation of multicellular organismal development	GO:2000026	414	0.017
regulation of cell proliferation	GO:0042127	163	0.017
kidney development	GO:0001822	3	0.017
respiratory system development	GO:0060541	213	0.017
localization of cell	GO:0051674	257	0.017
male gamete generation	GO:0048232	201	0.017
open tracheal system development	GO:0007424	204	0.017
meiotic nuclear division	GO:0007126	151	0.016
embryonic pattern specification	GO:0009880	174	0.016
epithelial cell differentiation	GO:0030855	322	0.016
developmental programmed cell death	GO:0010623	138	0.016
cell division	GO:0051301	248	0.016
digestive system development	GO:0055123	149	0.016
axon guidance	GO:0007411	233	0.016
nucleotide catabolic process	GO:0009166	109	0.016
regulation of cellular protein metabolic process	GO:0032268	243	0.016
positive regulation of signaling	GO:0023056	243	0.016
protein localization to organelle	GO:0033365	82	0.016
spermatid differentiation	GO:0048515	114	0.015
positive regulation of cell migration	GO:0030335	2	0.015
negative regulation of signal transduction	GO:0009968	206	0.015
nucleoside catabolic process	GO:0009164	112	0.015
homeostatic process	GO:0042592	199	0.015
dorsal ventral pattern formation	GO:0009953	133	0.015
taxis	GO:0042330	304	0.015
dendrite development	GO:0016358	204	0.015
regulation of cellular catabolic process	GO:0031329	157	0.015
glycosyl compound catabolic process	GO:1901658	112	0.015
regulation of cell differentiation	GO:0045595	302	0.015
germarium derived egg chamber formation	GO:0007293	101	0.015
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.015
positive regulation of molecular function	GO:0044093	136	0.015
negative regulation of cell death	GO:0060548	81	0.015
macromolecule catabolic process	GO:0009057	161	0.015
regulation of phosphorylation	GO:0042325	147	0.015
meiotic cell cycle	GO:0051321	171	0.015
maintenance of location	GO:0051235	73	0.015
telencephalon development	GO:0021537	2	0.014
purine containing compound catabolic process	GO:0072523	112	0.014
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.014
cuticle development	GO:0042335	86	0.014
ion transport	GO:0006811	145	0.014
regulation of cellular localization	GO:0060341	136	0.014
spindle organization	GO:0007051	253	0.014
regulation of protein metabolic process	GO:0051246	256	0.014
developmental pigmentation	GO:0048066	68	0.014
cellular macromolecule localization	GO:0070727	220	0.014
wing disc morphogenesis	GO:0007472	344	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
histolysis	GO:0007559	102	0.014
single organism membrane organization	GO:0044802	93	0.014
regulation of immune response	GO:0050776	118	0.014
ribonucleotide catabolic process	GO:0009261	109	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
development of primary sexual characteristics	GO:0045137	50	0.014
protein phosphorylation	GO:0006468	169	0.014
regulation of anatomical structure morphogenesis	GO:0022603	242	0.014
aromatic compound catabolic process	GO:0019439	166	0.014
antimicrobial peptide production	GO:0002775	46	0.014
gtp catabolic process	GO:0006184	72	0.014
ameboidal type cell migration	GO:0001667	151	0.013
positive regulation of cell communication	GO:0010647	250	0.013
dna replication	GO:0006260	48	0.013
positive regulation of nucleoside metabolic process	GO:0045979	47	0.013
imaginal disc derived leg morphogenesis	GO:0007480	80	0.013
dna integrity checkpoint	GO:0031570	81	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013
defense response to other organism	GO:0098542	225	0.013
oocyte differentiation	GO:0009994	145	0.013
cellular amine metabolic process	GO:0044106	12	0.013
axis specification	GO:0009798	167	0.013
negative regulation of programmed cell death	GO:0043069	72	0.013
cellular macromolecular complex assembly	GO:0034622	153	0.013
regulation of purine nucleotide metabolic process	GO:1900542	62	0.013
response to lipopolysaccharide	GO:0032496	4	0.013
protein catabolic process	GO:0030163	101	0.013
instar larval development	GO:0002168	55	0.013
sensory organ morphogenesis	GO:0090596	260	0.012
leg disc development	GO:0035218	92	0.012
regulation of cellular response to stress	GO:0080135	89	0.012
salivary gland histolysis	GO:0035070	88	0.012
eye morphogenesis	GO:0048592	260	0.012
female meiotic division	GO:0007143	70	0.012
response to organic substance	GO:0010033	284	0.012
regulation of cell cycle process	GO:0010564	181	0.012
maintenance of protein location	GO:0045185	28	0.012
stem cell proliferation	GO:0072089	88	0.012
mating	GO:0007618	120	0.012
autophagic cell death	GO:0048102	83	0.012
cell projection assembly	GO:0030031	94	0.012
regulation of mitotic cell cycle	GO:0007346	190	0.012
regulation of transport	GO:0051049	181	0.012
mitotic dna integrity checkpoint	GO:0044774	75	0.012
gland development	GO:0048732	191	0.012
tube development	GO:0035295	244	0.012
positive regulation of cell motility	GO:2000147	3	0.012
protein dna complex assembly	GO:0065004	63	0.012
chorion containing eggshell formation	GO:0007304	105	0.012
cellular response to organic substance	GO:0071310	132	0.012
response to light stimulus	GO:0009416	124	0.012
chromosome separation	GO:0051304	42	0.012
proteasomal protein catabolic process	GO:0010498	59	0.011
response to other organism	GO:0051707	293	0.011
peptide biosynthetic process	GO:0043043	42	0.011
tripartite regional subdivision	GO:0007351	103	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.011
purine nucleotide catabolic process	GO:0006195	109	0.011
positive regulation of phosphorylation	GO:0042327	87	0.011
eye pigmentation	GO:0048069	43	0.011
wound healing	GO:0042060	75	0.011
tissue migration	GO:0090130	155	0.011
tube morphogenesis	GO:0035239	191	0.011
negative regulation of intracellular signal transduction	GO:1902532	57	0.011
gastrulation with mouth forming first	GO:0001703	36	0.011
imaginal disc derived wing morphogenesis	GO:0007476	337	0.011
negative regulation of developmental process	GO:0051093	201	0.011
single fertilization	GO:0007338	24	0.011
imaginal disc derived appendage development	GO:0048737	399	0.011
gastrulation	GO:0007369	70	0.011
single organism cellular localization	GO:1902580	180	0.011
epithelial cell development	GO:0002064	274	0.011
hindbrain development	GO:0030902	2	0.011
multi multicellular organism process	GO:0044706	123	0.011
positive regulation of multicellular organismal process	GO:0051240	143	0.011
modification dependent protein catabolic process	GO:0019941	78	0.011
digestive tract development	GO:0048565	149	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
regulation of response to biotic stimulus	GO:0002831	63	0.011
peptidyl lysine modification	GO:0018205	57	0.011
maintenance of location in cell	GO:0051651	28	0.011
production of molecular mediator of immune response	GO:0002440	46	0.011
signal transduction in response to dna damage	GO:0042770	3	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
single organismal cell cell adhesion	GO:0016337	45	0.010
eye photoreceptor cell differentiation	GO:0001754	145	0.010
single organism cell adhesion	GO:0098602	47	0.010
positive regulation of developmental process	GO:0051094	143	0.010
organelle assembly	GO:0070925	198	0.010
negative regulation of rna metabolic process	GO:0051253	251	0.010
rho protein signal transduction	GO:0007266	14	0.010
antimicrobial humoral response	GO:0019730	99	0.010
organic acid metabolic process	GO:0006082	103	0.010
neuroblast proliferation	GO:0007405	74	0.010
atp metabolic process	GO:0046034	49	0.010
regulation of gene silencing	GO:0060968	63	0.010
cellular response to chemical stimulus	GO:0070887	199	0.010
amine metabolic process	GO:0009308	12	0.010
dendrite morphogenesis	GO:0048813	199	0.010
neuron projection guidance	GO:0097485	241	0.010
extrinsic apoptotic signaling pathway	GO:0097191	1	0.010
post embryonic appendage morphogenesis	GO:0035120	385	0.010
gtp metabolic process	GO:0046039	72	0.010

CG12877 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.016
inherited metabolic disorder	DOID:655	0.011
disease of metabolism	DOID:0014667	0.011

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