Drosophila melanogaster

79 known processes

mld (Dmel_CG34100)

molting defective

(Aliases: Mld,Dmel\CG34100,CG31312,CG34100,CG9469,CG13620,CG33343)

mld biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription from rna polymerase ii promoterGO:00063573780.398
growthGO:00400073590.236
multi organism reproductive behaviorGO:00447051210.199
positive regulation of macromolecule biosynthetic processGO:00105572830.199
chromosome organizationGO:00512763600.188
molting cycle chitin based cuticleGO:0007591560.178
positive regulation of nucleic acid templated transcriptionGO:19035082660.174
regulation of multicellular organismal developmentGO:20000264140.166
positive regulation of rna metabolic processGO:00512542710.161
imaginal disc derived appendage morphogenesisGO:00351143950.152
imaginal disc derived appendage developmentGO:00487373990.147
regulation of cell cycle phase transitionGO:19019871300.144
positive regulation of biosynthetic processGO:00098913160.140
positive regulation of transcription dna templatedGO:00458932660.135
transcription from rna polymerase ii promoterGO:00063663680.129
brain developmentGO:00074201200.127
spermatogenesisGO:00072832000.126
pigmentationGO:0043473750.123
negative regulation of signalingGO:00230572190.117
columnar cuboidal epithelial cell developmentGO:00020662490.114
male gamete generationGO:00482322010.114
reproductive behaviorGO:00190981220.113
eye developmentGO:00016543230.109
wing disc morphogenesisGO:00074723440.108
multicellular organismal reproductive behaviorGO:00330571100.103
axonogenesisGO:00074092900.097
tube morphogenesisGO:00352391910.097
positive regulation of rna biosynthetic processGO:19026802660.096
positive regulation of macromolecule metabolic processGO:00106044050.096
establishment of localization in cellGO:00516494020.094
regulation of synapse structure and activityGO:00508031280.089
negative regulation of transcription dna templatedGO:00458922370.088
chemosensory behaviorGO:00076351060.087
axon developmentGO:00615642970.086
positive regulation of nucleobase containing compound metabolic processGO:00459353320.086
blastoderm segmentationGO:00073501590.085
olfactory behaviorGO:0042048970.085
dendrite morphogenesisGO:00488131990.085
morphogenesis of an epitheliumGO:00020092760.080
cell deathGO:00082192790.079
positive regulation of cellular biosynthetic processGO:00313283160.078
axon cargo transportGO:0008088290.077
cellular component disassemblyGO:0022411460.076
negative regulation of nucleobase containing compound metabolic processGO:00459342610.075
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.075
positive regulation of signalingGO:00230562430.075
developmental growthGO:00485892800.073
segmentationGO:00352822070.072
multi multicellular organism processGO:00447061230.072
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.072
synaptic growth at neuromuscular junctionGO:00511241190.070
single organism behaviorGO:00447083910.069
positive regulation of nitrogen compound metabolic processGO:00511733540.069
sperm individualizationGO:0007291480.069
epithelial cell developmentGO:00020642740.069
synapse assemblyGO:00074161430.069
central nervous system developmentGO:00074172010.065
ovarian follicle cell developmentGO:00307072480.064
small molecule metabolic processGO:00442813050.063
regulation of growthGO:00400082330.062
negative regulation of mitotic cell cycleGO:00459301090.062
female gonad developmentGO:0008585120.061
positive regulation of gene expressionGO:00106282900.059
regulation of cell cycle processGO:00105641810.057
imaginal disc derived wing morphogenesisGO:00074763370.057
negative regulation of response to stimulusGO:00485852580.057
eye morphogenesisGO:00485922600.057
negative regulation of cellular biosynthetic processGO:00313272770.056
protein localizationGO:00081042840.054
digestive tract morphogenesisGO:00485461270.053
deathGO:00162652840.052
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.052
regulation of nervous system developmentGO:00519602480.052
regulation of developmental growthGO:00486381740.052
protein modification by small protein conjugation or removalGO:00706471060.052
mitotic cell cycle phase transitionGO:00447721380.050
positive regulation of response to stimulusGO:00485843230.049
long term memoryGO:0007616620.049
mating behaviorGO:00076171060.049
sensory organ morphogenesisGO:00905962600.048
cell cycle phase transitionGO:00447701400.048
vesicle mediated transportGO:00161923810.048
regulation of cell differentiationGO:00455953020.047
compound eye morphogenesisGO:00017452490.047
regulation of programmed cell deathGO:00430671520.046
synapse organizationGO:00508081960.045
multi organism behaviorGO:00517051750.044
negative regulation of signal transductionGO:00099682060.044
negative regulation of nucleic acid templated transcriptionGO:19035072400.044
post embryonic appendage morphogenesisGO:00351203850.043
neuromuscular junction developmentGO:00075281490.043
molting cycle processGO:0022404290.042
tube developmentGO:00352952440.041
cellular hormone metabolic processGO:0034754230.041
columnar cuboidal epithelial cell differentiationGO:00020652560.041
cellular ketone metabolic processGO:0042180240.041
developmental maturationGO:00217001720.041
compound eye developmentGO:00487493070.041
cellular response to dna damage stimulusGO:00069742230.041
head developmentGO:00603221350.041
secretion by cellGO:00329401010.040
mitotic dna integrity checkpointGO:0044774750.040
protein ubiquitinationGO:0016567700.040
chorion containing eggshell formationGO:00073041050.040
negative regulation of mitotic cell cycle phase transitionGO:19019911030.040
regulation of synapse assemblyGO:0051963940.038
protein transportGO:00150311550.038
establishment of synaptic vesicle localizationGO:0097480500.038
protein modification processGO:00362114380.038
ecdysteroid metabolic processGO:0045455190.038
dna packagingGO:0006323910.037
negative regulation of cellular component organizationGO:00511291080.036
regulation of mitotic cell cycle phase transitionGO:19019901300.036
positive regulation of canonical wnt signaling pathwayGO:009026370.036
chromosome condensationGO:0030261410.036
regulation of neurogenesisGO:00507671580.035
photoreceptor cell differentiationGO:00465301700.035
regulation of mitotic cell cycleGO:00073461900.035
male courtship behavior veined wing generated song productionGO:0045433200.035
spermatid differentiationGO:00485151140.035
dna conformation changeGO:00711031050.034
regionalizationGO:00030024160.034
cellular amino acid metabolic processGO:0006520610.034
courtship behaviorGO:0007619680.034
muscle structure developmentGO:00610612240.034
developmental pigmentationGO:0048066680.034
histone h3 acetylationGO:0043966110.033
response to sterolGO:0036314340.033
negative regulation of cell communicationGO:00106482230.033
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.033
negative regulation of cell cycle phase transitionGO:19019881030.033
negative regulation of rna biosynthetic processGO:19026792400.033
establishment of organelle localizationGO:00516561220.032
morphogenesis of follicular epitheliumGO:0016333360.032
organelle fissionGO:00482853400.032
dna metabolic processGO:00062592270.032
tissue migrationGO:00901301550.032
cellular protein localizationGO:00346131600.031
regulation of transportGO:00510491810.031
immune responseGO:00069552460.031
regulation of catabolic processGO:00098941700.031
negative regulation of rna metabolic processGO:00512532510.031
negative regulation of macromolecule biosynthetic processGO:00105582700.031
humoral immune responseGO:00069591170.030
regulation of compound eye retinal cell programmed cell deathGO:0046669180.030
cellular protein modification processGO:00064644380.030
terminal region determinationGO:0007362250.030
establishment or maintenance of cell polarityGO:00071631670.030
establishment of vesicle localizationGO:0051650510.030
salivary gland developmentGO:00074311620.030
tripartite regional subdivisionGO:00073511030.030
molting cycleGO:0042303560.029
cellular pigmentationGO:0033059120.029
cell motilityGO:00488702510.029
cell migrationGO:00164772380.029
intracellular transportGO:00469072280.029
negative regulation of microtubule depolymerizationGO:0007026210.029
organic substance transportGO:00717022570.029
embryonic pattern specificationGO:00098801740.029
single organism intracellular transportGO:19025822070.029
ovipositionGO:0018991190.028
organonitrogen compound metabolic processGO:19015643180.028
mushroom body developmentGO:0016319700.028
regulation of developmental pigmentationGO:0048070240.028
organic hydroxy compound metabolic processGO:1901615830.028
chromatin organizationGO:00063252070.027
establishment of protein localizationGO:00451841630.027
immune system processGO:00023763470.027
organic substance catabolic processGO:19015753080.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
regulation of establishment of protein localizationGO:0070201610.026
protein acetylationGO:0006473390.026
programmed cell deathGO:00125012570.026
nuclear divisionGO:00002803320.026
positive regulation of catalytic activityGO:00430851180.026
protein secretionGO:0009306450.026
organelle assemblyGO:00709251980.026
regulation of cell cycleGO:00517262910.026
appendage developmentGO:00487364010.025
eye photoreceptor cell developmentGO:0042462810.025
body morphogenesisGO:001017120.025
cytoplasm organizationGO:0007028640.025
cellular component assembly involved in morphogenesisGO:00109271510.025
locomotory behaviorGO:00076261760.025
negative regulation of synapse assemblyGO:0051964390.025
response to monosaccharideGO:003428440.025
negative regulation of gene expressionGO:00106293870.025
gtp catabolic processGO:0006184720.025
open tracheal system developmentGO:00074242040.024
maintenance of locationGO:0051235730.024
positive regulation of signal transductionGO:00099672230.024
retina development in camera type eyeGO:006004140.024
oxoacid metabolic processGO:00434361030.024
regulation of localizationGO:00328792750.024
chemotaxisGO:00069352490.023
regulation of cellular amine metabolic processGO:003323830.023
dendrite developmentGO:00163582040.023
gland developmentGO:00487321910.023
appendage morphogenesisGO:00351073970.023
regulation of anatomical structure sizeGO:00900661630.023
regulation of anatomical structure morphogenesisGO:00226032420.023
regulation of embryonic developmentGO:0045995680.023
negative regulation of cell cycle processGO:00109481090.023
gtp metabolic processGO:0046039720.022
spindle organizationGO:00070512530.022
negative regulation of cell cycleGO:00457861160.022
eye photoreceptor cell differentiationGO:00017541450.022
covalent chromatin modificationGO:00165691060.022
internal protein amino acid acetylationGO:0006475380.022
mitotic cell cycle embryonicGO:0045448380.022
spermatid developmentGO:0007286980.022
intracellular signal transductionGO:00355563000.022
negative regulation of cellular metabolic processGO:00313243820.022
cellular amine metabolic processGO:0044106120.022
regulation of synapse organizationGO:00508071100.022
response to other organismGO:00517072930.021
salivary gland cell autophagic cell deathGO:0035071830.021
taxisGO:00423303040.021
chromatin silencingGO:0006342760.021
salivary gland histolysisGO:0035070880.021
protein modification by small protein conjugationGO:0032446790.021
endocytosisGO:00068973100.021
compound eye photoreceptor cell differentiationGO:00017511400.021
cuticle pigmentationGO:0048067220.021
cellular response to gamma radiationGO:0071480100.021
camera type eye developmentGO:004301040.021
mitotic g2 m transition checkpointGO:0044818700.021
peptidyl lysine modificationGO:0018205570.021
regulation of organ morphogenesisGO:2000027780.021
small molecule biosynthetic processGO:0044283370.021
regulation of cellular protein metabolic processGO:00322682430.021
embryo development ending in birth or egg hatchingGO:00097921520.021
renal tubule developmentGO:0061326640.021
histone acetylationGO:0016573380.021
ovarian follicle cell migrationGO:00072971210.021
localization of cellGO:00516742570.020
defense response to bacteriumGO:00427421780.020
negative regulation of intracellular signal transductionGO:1902532570.020
regulation of synaptic growth at neuromuscular junctionGO:0008582890.020
eggshell formationGO:00307031050.020
chromatin remodelingGO:0006338720.020
macromolecular complex disassemblyGO:0032984370.020
response to external biotic stimulusGO:00432072930.020
axon guidanceGO:00074112330.020
leg disc developmentGO:0035218920.020
regulation of protein localizationGO:0032880760.020
compound eye photoreceptor developmentGO:0042051780.020
cilium assemblyGO:0042384380.020
regulation of execution phase of apoptosisGO:190011750.020
protein catabolic processGO:00301631010.020
positive regulation of developmental growthGO:0048639620.019
apoptotic processGO:00069151590.019
regulation of protein complex disassemblyGO:0043244290.019
negative regulation of nitrogen compound metabolic processGO:00511722650.019
guanosine containing compound catabolic processGO:1901069740.019
response to oxygen containing compoundGO:19017002000.019
microtubule based movementGO:0007018510.019
phagocytosisGO:00069092150.019
embryonic axis specificationGO:00005781070.019
nucleoside phosphate metabolic processGO:00067531620.019
epithelium migrationGO:00901321480.019
negative regulation of biosynthetic processGO:00098902770.019
regulation of intracellular signal transductionGO:19025312360.018
microtubule based transportGO:0010970420.018
regulation of protein metabolic processGO:00512462560.018
catabolic processGO:00090564090.018
regulation of cellular localizationGO:00603411360.018
cytoplasmic transportGO:00164821300.018
golgi organizationGO:0007030660.018
lipid metabolic processGO:00066291210.018
nucleoside catabolic processGO:00091641120.018
positive regulation of cell migrationGO:003033520.018
regulation of ras protein signal transductionGO:0046578930.018
morphogenesis of a polarized epitheliumGO:0001738930.018
ras protein signal transductionGO:0007265880.017
regulation of compound eye cone cell fate specificationGO:004268240.017
small gtpase mediated signal transductionGO:0007264880.017
gliogenesisGO:0042063800.017
neurological system processGO:00508773580.017
lipid homeostasisGO:0055088330.017
response to ketoneGO:1901654340.017
mitotic g2 dna damage checkpointGO:0007095690.017
positive regulation of cell communicationGO:00106472500.017
immune effector processGO:0002252980.017
spinal cord developmentGO:002151010.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
tissue morphogenesisGO:00487292970.017
wnt signaling pathwayGO:0016055980.017
proteolysis involved in cellular protein catabolic processGO:0051603830.017
regulation of molecular functionGO:00650092170.017
male mating behaviorGO:0060179700.016
intracellular protein transportGO:00068861040.016
regulation of gtpase activityGO:0043087440.016
regulation of tube architecture open tracheal systemGO:0035152680.016
digestive tract developmentGO:00485651490.016
actin filament based movementGO:0030048260.016
cation transportGO:00068121100.016
muscle organ developmentGO:00075171270.016
sterol homeostasisGO:005509240.016
leg disc morphogenesisGO:0007478800.016
anterior posterior axis specificationGO:00099481090.016
immune response regulating signaling pathwayGO:000276420.016
developmental cell growthGO:0048588520.016
developmental programmed cell deathGO:00106231380.016
regulation of immune system processGO:00026821760.016
anterior posterior pattern specificationGO:00099521360.015
nucleus organizationGO:0006997450.015
positive regulation of wnt signaling pathwayGO:0030177250.015
cilium organizationGO:0044782410.015
cellularizationGO:0007349900.015
cellular protein complex disassemblyGO:0043624350.015
matingGO:00076181200.015
epithelial cell migration open tracheal systemGO:0007427320.015
connective tissue developmentGO:006144830.015
cuticle developmentGO:0042335860.015
gastrulationGO:0007369700.015
establishment of planar polarityGO:0001736870.015
female sex differentiationGO:0046660200.015
glycosyl compound catabolic processGO:19016581120.014
chaeta developmentGO:0022416970.014
epithelial cell differentiationGO:00308553220.014
regulation of chitin based cuticle tanningGO:0007564140.014
regulation of organelle organizationGO:00330431960.014
epithelial cell migrationGO:00106311480.014
hindbrain developmentGO:003090220.014
melanin metabolic processGO:0006582470.014
hindgut developmentGO:0061525580.014
negative regulation of nervous system developmentGO:0051961920.014
developmental growth involved in morphogenesisGO:0060560650.014
secretionGO:00469031090.014
response to organic substanceGO:00100332840.014
purine ribonucleotide metabolic processGO:00091501450.014
endomembrane system organizationGO:00102561190.014
defense response to other organismGO:00985422250.014
response to lipopolysaccharideGO:003249640.014
ribonucleoside catabolic processGO:00424541120.014
g2 dna damage checkpointGO:0031572690.014
larval behaviorGO:0030537420.014
forebrain developmentGO:003090020.014
mitotic cell cycle checkpointGO:0007093880.014
positive regulation of hydrolase activityGO:0051345780.014
regulation of protein modification processGO:00313991120.013
peptidyl amino acid modificationGO:00181931050.013
jak stat cascadeGO:0007259490.013
chromosome segregationGO:00070591570.013
pole plasm assemblyGO:0007315610.013
cholesterol homeostasisGO:004263230.013
regulation of protein catabolic processGO:0042176550.013
regulation of cellular ketone metabolic processGO:001056530.013
regulation of gene silencingGO:0060968630.013
organophosphate catabolic processGO:00464341120.013
protein localization to nucleusGO:0034504550.013
organic acid metabolic processGO:00060821030.013
positive regulation of protein metabolic processGO:00512471280.013
carboxylic acid metabolic processGO:0019752920.013
anterior posterior axis specification embryoGO:00085951030.013
gene silencingGO:00164581380.013
gastrulation involving germ band extensionGO:0010004360.013
autophagic cell deathGO:0048102830.013
positive regulation of programmed cell deathGO:0043068620.013
response to alcoholGO:0097305950.013
golgi vesicle transportGO:0048193270.013
defense responseGO:00069523000.013
regulation of immune responseGO:00507761180.013
innate immune responseGO:00450871440.013
photoreceptor cell fate commitmentGO:0046552410.013
malpighian tubule developmentGO:0072002640.013
response to radiationGO:00093141550.013
alcohol metabolic processGO:0006066250.013
antimicrobial humoral responseGO:0019730990.013
regulation of chromatin silencingGO:0031935360.012
negative regulation of protein complex disassemblyGO:0043242230.012
cell divisionGO:00513012480.012
pupal developmentGO:0035209110.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
gastrulation with mouth forming firstGO:0001703360.012
stem cell proliferationGO:0072089880.012
purine nucleoside catabolic processGO:00061521120.012
regulation of cellular amino acid metabolic processGO:000652100.012
cellular catabolic processGO:00442483720.012
regulation of multi organism processGO:00439001310.012
single organism biosynthetic processGO:00447112060.012
internal peptidyl lysine acetylationGO:0018393380.012
development of primary female sexual characteristicsGO:0046545120.012
regulation of phosphorus metabolic processGO:00511742100.012
regulation of protein transportGO:0051223570.012
imaginal disc derived leg morphogenesisGO:0007480800.012
hormone metabolic processGO:0042445330.012
single organism cellular localizationGO:19025801800.012
g1 s transition of mitotic cell cycleGO:0000082310.012
protein targeting to nucleusGO:0044744510.012
negative regulation of cellular protein metabolic processGO:0032269850.011
positive regulation of phosphorus metabolic processGO:00105621390.011
nucleoside phosphate catabolic processGO:19012921100.011
response to ecdysoneGO:0035075340.011
regulation of circadian rhythmGO:0042752490.011
cell type specific apoptotic processGO:0097285380.011
ecdysone biosynthetic processGO:000669790.011
histone ubiquitinationGO:001657440.011
purine containing compound metabolic processGO:00725211550.011
response to biotic stimulusGO:00096072940.011
membrane organizationGO:00610241120.011
mitotic nuclear divisionGO:00070672130.011
regulation of antimicrobial peptide productionGO:0002784440.011
regulation of gtp catabolic processGO:0033124440.011
cell cycle arrestGO:000705040.011
neuron recognitionGO:00080381010.011
regulation of canonical wnt signaling pathwayGO:0060828150.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of secretionGO:0051046440.011
negative regulation of immune system processGO:0002683500.011
learningGO:0007612750.011
embryonic morphogenesisGO:00485982060.011
negative regulation of gene expression epigeneticGO:0045814770.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
immune response activating signal transductionGO:000275720.011
negative regulation of developmental growthGO:0048640640.011
axon target recognitionGO:0007412160.011
positive regulation of developmental processGO:00510941430.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of phosphate metabolic processGO:00192202100.011
male courtship behavior veined wing extensionGO:0048065220.011
negative regulation of epithelial cell proliferationGO:005068040.011
modification dependent macromolecule catabolic processGO:0043632790.011
establishment of cell polarityGO:0030010400.011
regulation of dna templated transcription elongationGO:0032784170.011
synaptic vesicle localizationGO:0097479530.011
rna splicingGO:0008380830.010
response to gravityGO:0009629260.010
protein acylationGO:0043543420.010
nucleotide metabolic processGO:00091171610.010
pole plasm mrna localizationGO:0019094490.010
amine metabolic processGO:0009308120.010
extracellular structure organizationGO:0043062460.010
positive regulation of catabolic processGO:00098961050.010
sensory perceptionGO:00076001960.010
synaptic vesicle transportGO:0048489500.010
anatomical structure homeostasisGO:0060249970.010
response to abiotic stimulusGO:00096283410.010
hematopoietic or lymphoid organ developmentGO:0048534570.010
neuron projection guidanceGO:00974852410.010
substrate adhesion dependent cell spreadingGO:003444620.010
muscle attachmentGO:0016203360.010
cellular response to chemical stimulusGO:00708871990.010

mld disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.038
disease of anatomical entityDOID:700.038
disease of cellular proliferationDOID:1456600.037
organ system cancerDOID:005068600.037
cancerDOID:16200.037
sensory system diseaseDOID:005015500.015
cardiovascular system diseaseDOID:128700.013