Drosophila melanogaster

232 known processes

BubR1 (Dmel_CG7838)

Bub1-related kinase

(Aliases: bubr1,bub1,Bub1,BcDNA:LD23835,dBUB1,31/13,Dmbub1,l(2)k06109,bubR1,CG 7838,l(2)k03113,Mad3,DmBUB1,BUB1,Dmel\CG7838,BUBR1,CG7838)

BubR1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear divisionGO:00002803320.999
organelle fissionGO:00482853400.999
meiotic cell cycleGO:00513211710.998
male meiosisGO:0007140520.998
meiotic nuclear divisionGO:00071261510.996
centrosome cycleGO:00070981370.995
spindle organizationGO:00070512530.993
mitotic spindle organizationGO:00070522200.992
chromosome organizationGO:00512763600.992
mitotic sister chromatid separationGO:0051306300.991
chromosome segregationGO:00070591570.984
sister chromatid segregationGO:0000819920.978
centrosome duplicationGO:00512981210.974
spindle assembly involved in meiosisGO:0090306200.973
chromosome condensationGO:0030261410.967
spindle assembly involved in mitosisGO:0090307500.919
microtubule organizing center organizationGO:00310231680.904
regulation of mitotic sister chromatid segregationGO:0033047280.896
meiotic spindle organizationGO:0000212360.894
dna conformation changeGO:00711031050.882
dna metabolic processGO:00062592270.875
meiotic cell cycle processGO:19030461320.874
meiotic chromosome segregationGO:0045132590.834
mitotic sister chromatid segregationGO:0000070870.824
spindle assembly involved in female meiosisGO:0007056140.775
spindle assemblyGO:0051225800.759
negative regulation of chromosome segregationGO:0051985140.737
regulation of mitotic spindle organizationGO:006023690.718
dna packagingGO:0006323910.708
regulation of mitotic cell cycle phase transitionGO:19019901300.680
regulation of mitotic metaphase anaphase transitionGO:0030071260.666
regulation of cell cycle phase transitionGO:19019871300.651
microtubule polymerization or depolymerizationGO:0031109390.635
cell cycle phase transitionGO:00447701400.635
mitotic cell cycle phase transitionGO:00447721380.634
spindle assembly involved in female meiosis iGO:000705750.605
negative regulation of mitotic sister chromatid separationGO:2000816130.601
microtubule cytoskeleton organization involved in mitosisGO:1902850520.579
negative regulation of mitotic cell cycle phase transitionGO:19019911030.570
mitotic spindle stabilizationGO:004314860.543
protein complex assemblyGO:00064612000.543
regulation of mitosisGO:0007088560.534
cellular protein complex assemblyGO:0043623710.521
metaphase anaphase transition of cell cycleGO:0044784280.520
female meiotic divisionGO:0007143700.486
male meiosis cytokinesisGO:0007112260.483
mitotic chromosome condensationGO:0007076220.475
pronuclear migrationGO:003504640.474
protein polymerizationGO:0051258420.471
centrosome organizationGO:00512971630.447
female meiosis iGO:000714480.423
macromolecular complex assemblyGO:00650032560.422
mitotic centrosome separationGO:000710080.404
centrosome separationGO:0051299200.371
negative regulation of cell cycleGO:00457861160.362
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.356
regulation of cell divisionGO:0051302720.348
meiosis iGO:0007127590.339
metaphase anaphase transition of mitotic cell cycleGO:0007091280.337
organelle assemblyGO:00709251980.324
mitotic nuclear divisionGO:00070672130.320
regulation of sister chromatid segregationGO:0033045280.319
positive regulation of mitotic sister chromatid separationGO:1901970100.298
establishment or maintenance of cell polarityGO:00071631670.285
mitotic spindle elongationGO:0000022810.285
chromosome separationGO:0051304420.267
gonad developmentGO:0008406500.253
cystoblast divisionGO:0007282100.247
regulation of mitotic sister chromatid separationGO:0010965280.243
histone modificationGO:00165701060.242
regulation of mitotic cell cycleGO:00073461900.241
regulation of chromosome segregationGO:0051983320.233
negative regulation of mitotic cell cycleGO:00459301090.229
regulation of chromosome organizationGO:0033044640.201
negative regulation of biosynthetic processGO:00098902770.185
meiosis iiGO:0007135230.181
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.177
cell divisionGO:00513012480.174
negative regulation of mitotic sister chromatid segregationGO:0033048130.173
regulation of proteasomal protein catabolic processGO:0061136390.173
dna integrity checkpointGO:0031570810.165
mitotic spindle checkpointGO:0071174110.158
regulation of nuclear divisionGO:0051783580.157
spindle midzone assemblyGO:005125540.156
regulation of mitotic spindle elongationGO:003288810.155
cellular response to dna damage stimulusGO:00069742230.154
dna dependent dna replicationGO:0006261170.140
mitotic g2 m transition checkpointGO:0044818700.136
mitotic cytokinesisGO:0000281500.133
regulation of metaphase anaphase transition of cell cycleGO:1902099260.130
microtubule polymerizationGO:0046785150.130
cellular macromolecular complex assemblyGO:00346221530.124
synaptonemal complex organizationGO:007019350.123
nuclear dna replicationGO:003326010.122
chromatin organizationGO:00063252070.121
embryo development ending in birth or egg hatchingGO:00097921520.115
regulation of microtubule cytoskeleton organizationGO:0070507410.111
positive regulation of catalytic activityGO:00430851180.110
kinetochore organizationGO:005138390.105
development of primary sexual characteristicsGO:0045137500.104
larval developmentGO:00021641040.103
dna recombinationGO:0006310320.102
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.102
negative regulation of cell divisionGO:0051782170.098
regulation of spindle elongationGO:003288710.096
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.096
nucleus localizationGO:0051647340.094
asymmetric stem cell divisionGO:0098722490.091
centriole replicationGO:0007099240.088
positive regulation of macromolecule metabolic processGO:00106044050.085
chromatin modificationGO:00165681470.085
regulation of cell cycle processGO:00105641810.084
cellular protein modification processGO:00064644380.080
negative regulation of cell cycle processGO:00109481090.079
mitotic cell cycle checkpointGO:0007093880.077
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.077
sister chromatid cohesionGO:0007062180.077
regulation of microtubule based processGO:0032886490.076
negative regulation of cellular metabolic processGO:00313243820.074
lateral inhibitionGO:00463312060.074
neuronal stem cell divisionGO:0036445350.072
chromosome movement towards spindle poleGO:005130540.072
pronuclear fusionGO:000734440.066
dna damage checkpointGO:0000077780.065
protein modification processGO:00362114380.064
oocyte maturationGO:000155630.064
spindle checkpointGO:0031577110.063
mitotic spindle assembly checkpointGO:0007094110.061
cell cell signaling involved in cell fate commitmentGO:00451682100.060
purine nucleoside triphosphate metabolic processGO:00091441190.060
regulation of dna metabolic processGO:0051052340.060
negative regulation of cell cycle phase transitionGO:19019881030.058
brain developmentGO:00074201200.058
proteolysis involved in cellular protein catabolic processGO:0051603830.057
regulation of cellular protein catabolic processGO:1903362440.055
vesicle mediated transportGO:00161923810.055
regulation of dna replicationGO:0006275130.054
regulation of cellular catabolic processGO:00313291570.053
cytokinesisGO:0000910900.052
positive regulation of phosphate metabolic processGO:00459371390.052
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.051
meiotic dna double strand break processingGO:000070630.051
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.050
meiotic sister chromatid segregationGO:004514460.049
dna geometric changeGO:0032392160.049
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.049
cellular catabolic processGO:00442483720.048
sperm axoneme assemblyGO:0007288130.048
single organism catabolic processGO:00447122280.047
ras protein signal transductionGO:0007265880.045
germ line cyst formationGO:0048134440.045
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.044
organic substance transportGO:00717022570.044
modification dependent protein catabolic processGO:0019941780.044
germarium derived female germ line cyst formationGO:0030727420.042
negative regulation of sister chromatid segregationGO:0033046130.041
somatic stem cell divisionGO:0048103370.041
cell proliferationGO:00082832990.041
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.038
regulation of catalytic activityGO:00507901850.038
meiotic chromosome condensationGO:001003230.038
nucleobase containing compound catabolic processGO:00346551650.037
negative regulation of chromosome organizationGO:2001251190.036
asymmetric neuroblast divisionGO:0055059330.036
positive regulation of cellular protein metabolic processGO:00322701180.035
g2 dna damage checkpointGO:0031572690.035
positive regulation of nucleobase containing compound metabolic processGO:00459353320.034
regulation of g2 m transition of mitotic cell cycleGO:0010389150.034
dna replicationGO:0006260480.033
positive regulation of chromosome segregationGO:0051984100.033
centriole assemblyGO:0098534240.033
meiotic cytokinesisGO:0033206330.032
positive regulation of nitrogen compound metabolic processGO:00511733540.031
sex differentiationGO:0007548810.031
negative regulation of cellular component organizationGO:00511291080.031
organonitrogen compound metabolic processGO:19015643180.031
female meiosis chromosome segregationGO:0016321330.030
mitotic g2 dna damage checkpointGO:0007095690.030
microtubule anchoringGO:0034453110.030
g2 m transition of mitotic cell cycleGO:0000086190.030
reproductive system developmentGO:0061458740.030
negative regulation of proteolysisGO:0045861310.030
nucleoside phosphate metabolic processGO:00067531620.029
dna replication initiationGO:000627060.028
regulation of intracellular signal transductionGO:19025312360.027
reproductive structure developmentGO:0048608740.027
cytoskeleton dependent cytokinesisGO:0061640810.026
purine ribonucleoside triphosphate metabolic processGO:00092051190.026
nucleoside phosphate catabolic processGO:19012921100.026
protein complex biogenesisGO:00702712010.026
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.025
nuclear envelope organizationGO:000699870.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
purine nucleoside catabolic processGO:00061521120.024
regulation of molecular functionGO:00650092170.023
positive regulation of response to stimulusGO:00485843230.023
response to abiotic stimulusGO:00096283410.023
negative regulation of cellular biosynthetic processGO:00313272770.023
response to organic substanceGO:00100332840.022
nuclear migrationGO:0007097200.022
regulation of catabolic processGO:00098941700.022
positive regulation of cell cycle processGO:0090068280.022
spindle elongationGO:0051231830.022
neuroblast proliferationGO:0007405740.021
head developmentGO:00603221350.021
gene silencingGO:00164581380.021
negative regulation of rna biosynthetic processGO:19026792400.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
microtubule bundle formationGO:0001578270.021
endomembrane system organizationGO:00102561190.021
positive regulation of mitotic cell cycleGO:0045931340.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
purine ribonucleoside metabolic processGO:00461281270.020
ribonucleoside triphosphate catabolic processGO:00092031080.020
establishment of spindle orientationGO:0051294180.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
negative regulation of rna metabolic processGO:00512532510.020
forebrain developmentGO:003090020.019
positive regulation of protein transportGO:0051222370.019
microtubule nucleationGO:000702080.019
karyogamyGO:000074140.018
metaphase plate congressionGO:0051310190.018
cell cycle checkpointGO:0000075950.018
protein phosphorylationGO:00064681690.018
macromolecule catabolic processGO:00090571610.018
positive regulation of cellular component biogenesisGO:0044089800.018
mitotic sister chromatid cohesionGO:000706460.017
negative regulation of proteasomal protein catabolic processGO:1901799160.017
embryonic cleavageGO:004001650.017
aromatic compound catabolic processGO:00194391660.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
positive regulation of signalingGO:00230562430.017
maintenance of locationGO:0051235730.017
establishment of meiotic spindle orientationGO:005129620.017
chitin based larval cuticle pattern formationGO:0035293110.017
neuronal stem cell maintenanceGO:009715040.016
heterochromatin organization involved in chromatin silencingGO:007086890.016
organophosphate metabolic processGO:00196371950.016
proteolysisGO:00065081920.016
covalent chromatin modificationGO:00165691060.016
attachment of spindle microtubules to kinetochoreGO:000860850.016
distributive segregationGO:003283760.016
purine ribonucleotide catabolic processGO:00091541090.016
heterocycle catabolic processGO:00467001660.016
regulation of hemocyte proliferationGO:0035206370.016
regulation of organelle organizationGO:00330431960.016
reciprocal meiotic recombinationGO:0007131190.015
dna duplex unwindingGO:0032508160.015
positive regulation of protein modification processGO:0031401580.015
regulation of chromatin bindingGO:003556130.015
protein importGO:0017038550.015
dna endoreduplicationGO:0042023220.014
regulation of cytoskeleton organizationGO:0051493890.014
protein localization to organelleGO:0033365820.014
Human Mouse
mitotic spindle midzone assemblyGO:005125610.014
cell cycle g2 m phase transitionGO:0044839220.014
membrane organizationGO:00610241120.014
regulation of neuron differentiationGO:00456641030.014
regulation of meiosisGO:004002030.014
icosanoid biosynthetic processGO:004645610.014
positive regulation of developmental processGO:00510941430.014
endocytosisGO:00068973100.014
peptidyl threonine modificationGO:001821030.014
regulation of spindle organizationGO:0090224170.013
ribose phosphate metabolic processGO:00196931450.013
maintenance of protein locationGO:0045185280.013
reciprocal dna recombinationGO:0035825190.013
positive regulation of protein metabolic processGO:00512471280.013
pole cell migrationGO:0007280130.013
regulation of cell cycleGO:00517262910.013
nucleoside catabolic processGO:00091641120.013
positive regulation of gene expressionGO:00106282900.013
positive regulation of phosphorus metabolic processGO:00105621390.013
cytoplasmic transportGO:00164821300.013
regulation of cellular protein metabolic processGO:00322682430.013
ribonucleoside catabolic processGO:00424541120.013
regulation of nervous system developmentGO:00519602480.013
spindle assembly involved in male meiosisGO:000705350.013
peptidyl threonine phosphorylationGO:001810720.013
positive regulation of signal transductionGO:00099672230.013
nucleolus organizationGO:000700040.013
organic cyclic compound catabolic processGO:19013611680.013
genitalia developmentGO:0048806260.013
single organism biosynthetic processGO:00447112060.012
negative regulation of neurogenesisGO:0050768530.012
neural precursor cell proliferationGO:0061351750.012
body morphogenesisGO:001017120.012
apoptotic processGO:00069151590.012
neuroblast divisionGO:0055057350.012
ribonucleotide metabolic processGO:00092591450.012
telomere cappingGO:0016233110.012
meiotic spindle midzone assemblyGO:005125730.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
digestive tract developmentGO:00485651490.012
organonitrogen compound catabolic processGO:19015651280.012
positive regulation of cellular biosynthetic processGO:00313283160.011
establishment of protein localizationGO:00451841630.011
actomyosin structure organizationGO:0031032560.011
regulation of establishment of protein localizationGO:0070201610.011
organophosphate biosynthetic processGO:0090407460.011
nucleoside triphosphate metabolic processGO:00091411200.011
fatty acid derivative biosynthetic processGO:190157010.011
regulation of transcription by chromatin organizationGO:003440130.011
positive regulation of cellular catabolic processGO:0031331950.011
regulation of growthGO:00400082330.011
cellular protein localizationGO:00346131600.011
Human Mouse
negative regulation of transcription dna templatedGO:00458922370.011
nucleoside monophosphate catabolic processGO:0009125390.011
histone mrna metabolic processGO:000833480.011
actin cytoskeleton organizationGO:00300362060.011
positive regulation of rna biosynthetic processGO:19026802660.011
response to external biotic stimulusGO:00432072930.011
positive regulation of molecular functionGO:00440931360.011
protein processingGO:0016485680.011
female germ line cyst formationGO:0048135420.011
glycosyl compound metabolic processGO:19016571270.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
regulation of neurogenesisGO:00507671580.010
protein maturationGO:0051604710.010
establishment of nucleus localizationGO:0040023260.010
single fertilizationGO:0007338240.010
meiotic g2 mi transitionGO:000831530.010

BubR1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org