Drosophila melanogaster

4 known processes

Spn77Bb (Dmel_CG6663)

Serpin 77Bb

(Aliases: Dmel\CG6663,CG6266,CG6663)

Spn77Bb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inseminationGO:0007320220.606
sperm competitionGO:0046692210.375
sperm storageGO:0046693100.169
sterol homeostasisGO:005509240.161
regulation of sequestering of triglycerideGO:001088930.111
cholesterol homeostasisGO:004263230.101
acylglycerol catabolic processGO:004646430.096
matingGO:00076181200.096
positive regulation of lipid storageGO:001088440.090
phospholipid homeostasisGO:005509110.087
negative regulation of female receptivityGO:0007621140.086
triglyceride catabolic processGO:001943330.085
regulation of female receptivity post matingGO:0046008170.079
female mating behaviorGO:0060180300.076
anion homeostasisGO:005508130.073
regulation of female receptivityGO:0045924240.069
regulation of localizationGO:00328792750.060
multicellular organismal reproductive behaviorGO:00330571100.059
neutral lipid biosynthetic processGO:004646020.059
acylglycerol biosynthetic processGO:004646320.059
oxoacid metabolic processGO:00434361030.055
body morphogenesisGO:001017120.052
wing disc morphogenesisGO:00074723440.052
response to other organismGO:00517072930.051
cellular catabolic processGO:00442483720.051
glycerolipid catabolic processGO:004650330.050
vesicle mediated transportGO:00161923810.048
organonitrogen compound metabolic processGO:19015643180.047
proteolysisGO:00065081920.047
developmental growthGO:00485892800.047
imaginal disc derived appendage morphogenesisGO:00351143950.046
organic acid metabolic processGO:00060821030.045
homeostatic processGO:00425921990.045
cholesterol transportGO:003030120.045
negative regulation of female receptivity post matingGO:0045434120.044
endocytosisGO:00068973100.043
alditol phosphate metabolic processGO:005264620.042
ethanolamine containing compound metabolic processGO:004243940.042
small molecule metabolic processGO:00442813050.042
immune responseGO:00069552460.040
defense responseGO:00069523000.040
positive regulation of sequestering of triglycerideGO:001089010.040
copulationGO:0007620260.040
response to oxygen containing compoundGO:19017002000.039
catabolic processGO:00090564090.039
triglyceride biosynthetic processGO:001943220.039
response to copper ionGO:004668840.039
post embryonic appendage morphogenesisGO:00351203850.038
cellular protein modification processGO:00064644380.037
growthGO:00400073590.037
macromolecular complex assemblyGO:00650032560.037
imaginal disc derived appendage developmentGO:00487373990.037
defense response to bacteriumGO:00427421780.036
response to external biotic stimulusGO:00432072930.036
response to biotic stimulusGO:00096072940.035
cellular amino acid metabolic processGO:0006520610.035
phagocytosisGO:00069092150.035
neurological system processGO:00508773580.034
carboxylic acid metabolic processGO:0019752920.034
response to abiotic stimulusGO:00096283410.034
exocrine system developmentGO:00352721620.033
defense response to other organismGO:00985422250.033
multi multicellular organism processGO:00447061230.033
response to organic substanceGO:00100332840.033
multi organism behaviorGO:00517051750.032
protein modification processGO:00362114380.032
cellular response to chemical stimulusGO:00708871990.032
salivary gland developmentGO:00074311620.032
positive regulation of cell communicationGO:00106472500.031
chemical homeostasisGO:0048878920.031
positive regulation of nitrogen compound metabolic processGO:00511733540.030
lipid homeostasisGO:0055088330.030
regionalizationGO:00030024160.030
imaginal disc derived wing morphogenesisGO:00074763370.030
mitotic spindle organizationGO:00070522200.030
regulation of transportGO:00510491810.029
response to temperature stimulusGO:00092661060.029
mating behaviorGO:00076171060.029
protein complex biogenesisGO:00702712010.029
positive regulation of response to stimulusGO:00485843230.029
cell proliferationGO:00082832990.029
spindle organizationGO:00070512530.029
regulation of immune responseGO:00507761180.029
negative regulation of developmental processGO:00510932010.028
organelle assemblyGO:00709251980.028
neutral lipid catabolic processGO:004646130.028
protein hydroxylationGO:001812610.028
regulation of sterol transportGO:003237110.028
regulation of multicellular organismal developmentGO:20000264140.027
cellular component assembly involved in morphogenesisGO:00109271510.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
single organism behaviorGO:00447083910.027
respiratory system developmentGO:00605412130.027
defense response to gram negative bacteriumGO:0050829940.026
phosphatidic acid metabolic processGO:004647310.026
chromosome organizationGO:00512763600.026
immune system processGO:00023763470.026
response to bacteriumGO:00096171980.026
humoral immune responseGO:00069591170.025
response to extracellular stimulusGO:00099911160.025
appendage developmentGO:00487364010.024
single organism biosynthetic processGO:00447112060.024
cell divisionGO:00513012480.024
blastoderm segmentationGO:00073501590.024
gland developmentGO:00487321910.023
carbohydrate derivative metabolic processGO:19011352170.023
sensory perceptionGO:00076001960.023
peptide metabolic processGO:0006518800.023
nuclear divisionGO:00002803320.023
single organism catabolic processGO:00447122280.023
amine metabolic processGO:0009308120.023
segmentationGO:00352822070.023
appendage morphogenesisGO:00351073970.023
transcription from rna polymerase ii promoterGO:00063663680.023
regulation of lipid storageGO:0010883220.022
positive regulation of biosynthetic processGO:00098913160.022
antimicrobial humoral responseGO:0019730990.022
axis specificationGO:00097981670.022
cellular lipid metabolic processGO:0044255830.022
embryonic pattern specificationGO:00098801740.022
organic substance transportGO:00717022570.022
glycoprotein metabolic processGO:0009100410.022
compound eye developmentGO:00487493070.022
organic substance catabolic processGO:19015753080.022
positive regulation of transcription dna templatedGO:00458932660.022
negative regulation of signalingGO:00230572190.022
locomotory behaviorGO:00076261760.022
regulation of cell differentiationGO:00455953020.021
regulation of cell cycleGO:00517262910.021
gland morphogenesisGO:00226121450.021
open tracheal system developmentGO:00074242040.021
carbohydrate derivative biosynthetic processGO:1901137850.021
negative regulation of signal transductionGO:00099682060.021
positive regulation of signalingGO:00230562430.021
cellular modified amino acid metabolic processGO:0006575450.021
compound eye morphogenesisGO:00017452490.021
positive regulation of cellular biosynthetic processGO:00313283160.021
forebrain developmentGO:003090020.021
positive regulation of rna biosynthetic processGO:19026802660.021
cellular amine metabolic processGO:0044106120.021
regulation of lipid transportGO:003236830.021
rhythmic processGO:00485111060.020
cellular response to dna damage stimulusGO:00069742230.020
response to lipopolysaccharideGO:003249640.020
positive regulation of signal transductionGO:00099672230.020
adult behaviorGO:00305341370.020
cell deathGO:00082192790.020
maintenance of locationGO:0051235730.020
sulfur compound biosynthetic processGO:0044272160.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
gene silencingGO:00164581380.019
organelle fissionGO:00482853400.019
positive regulation of multicellular organismal processGO:00512401430.019
negative regulation of response to stimulusGO:00485852580.019
wound healingGO:0042060750.019
dna metabolic processGO:00062592270.019
negative regulation of gene expressionGO:00106293870.019
notch signaling pathwayGO:00072191200.019
peptidyl proline modificationGO:001820830.019
cellular response to organic substanceGO:00713101320.019
regulation of immune system processGO:00026821760.019
organic hydroxy compound metabolic processGO:1901615830.019
photoreceptor cell developmentGO:0042461960.019
positive regulation of transportGO:0051050920.019
organophosphate catabolic processGO:00464341120.019
epithelial cell developmentGO:00020642740.019
kidney developmentGO:000182230.019
salivary gland morphogenesisGO:00074351450.019
muscle structure developmentGO:00610612240.019
regulation of multi organism processGO:00439001310.019
developmental maturationGO:00217001720.018
tissue morphogenesisGO:00487292970.018
regulation of cholesterol transportGO:003237410.018
positive regulation of macromolecule biosynthetic processGO:00105572830.018
regulation of humoral immune responseGO:0002920510.018
protein maturationGO:0051604710.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
cellular macromolecule catabolic processGO:00442651360.018
camera type eye developmentGO:004301040.018
regulation of cell cycle phase transitionGO:19019871300.018
negative regulation of cell differentiationGO:00455961430.018
phosphatidylethanolamine metabolic processGO:004633710.018
negative regulation of multicellular organismal processGO:00512411420.018
tube developmentGO:00352952440.018
ion homeostasisGO:0050801550.018
embryonic morphogenesisGO:00485982060.018
response to organic cyclic compoundGO:0014070890.018
negative regulation of cell communicationGO:00106482230.018
response to hexoseGO:000974630.018
epithelial cell differentiationGO:00308553220.017
muscle organ developmentGO:00075171270.017
antimicrobial peptide productionGO:0002775460.017
sulfur compound metabolic processGO:0006790590.017
positive regulation of rna metabolic processGO:00512542710.017
regulation of production of molecular mediator of immune responseGO:0002700440.017
cellular response to endogenous stimulusGO:0071495800.017
immune effector processGO:0002252980.017
regulation of cellular amide metabolic processGO:0034248390.017
telencephalon developmentGO:002153720.017
anterior posterior pattern specificationGO:00099521360.017
regulation of response to biotic stimulusGO:0002831630.017
proteoglycan biosynthetic processGO:0030166100.017
deathGO:00162652840.017
establishment of localization in cellGO:00516494020.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.016
reproductive behaviorGO:00190981220.016
anterior posterior axis specificationGO:00099481090.016
innate immune responseGO:00450871440.016
regulation of cell developmentGO:00602842150.016
embryo development ending in birth or egg hatchingGO:00097921520.016
positive regulation of macromolecule metabolic processGO:00106044050.016
multi organism reproductive behaviorGO:00447051210.016
embryonic development via the syncytial blastodermGO:00017001480.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
tripartite regional subdivisionGO:00073511030.016
morphogenesis of an epitheliumGO:00020092760.016
anterior posterior axis specification embryoGO:00085951030.016
cytokinesisGO:0000910900.016
chromatin organizationGO:00063252070.016
eye morphogenesisGO:00485922600.016
regulation of notch signaling pathwayGO:00085931000.016
eye developmentGO:00016543230.015
cell cycle phase transitionGO:00447701400.015
response to monosaccharideGO:003428440.015
regulation of cellular protein metabolic processGO:00322682430.015
digestive tract developmentGO:00485651490.015
connective tissue developmentGO:006144830.015
taxisGO:00423303040.015
regulation of protein metabolic processGO:00512462560.015
negative regulation of cellular metabolic processGO:00313243820.015
ubiquitin dependent protein catabolic processGO:0006511780.015
regulation of defense responseGO:00313471020.015
biological adhesionGO:00226101380.015
regulation of catalytic activityGO:00507901850.015
regulation of antimicrobial humoral responseGO:0002759500.015
regulation of molecular functionGO:00650092170.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
embryonic axis specificationGO:00005781070.015
oxidation reduction processGO:00551141230.015
regulation of proteolysisGO:0030162870.015
negative regulation of rna metabolic processGO:00512532510.015
regulation of cellular catabolic processGO:00313291570.015
regulation of response to external stimulusGO:00321011150.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
head developmentGO:00603221350.015
modification dependent macromolecule catabolic processGO:0043632790.015
compound eye photoreceptor developmentGO:0042051780.015
mitotic cell cycle phase transitionGO:00447721380.014
eye photoreceptor cell differentiationGO:00017541450.014
negative regulation of cellular biosynthetic processGO:00313272770.014
regulation of developmental growthGO:00486381740.014
cytoskeleton dependent cytokinesisGO:0061640810.014
lipid storageGO:0019915380.014
lipid metabolic processGO:00066291210.014
spermatogenesisGO:00072832000.014
regulation of response to stressGO:00801342000.014
circadian rhythmGO:00076231050.014
spindle elongationGO:0051231830.014
regulation of growthGO:00400082330.014
protein processingGO:0016485680.014
striated muscle cell differentiationGO:0051146900.014
positive regulation of gene expressionGO:00106282900.014
response to endogenous stimulusGO:00097191190.014
phosphorylationGO:00163102940.014
digestive system developmentGO:00551231490.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
macromolecule catabolic processGO:00090571610.014
spindle assemblyGO:0051225800.014
establishment or maintenance of cell polarityGO:00071631670.014
programmed cell deathGO:00125012570.014
defense response to fungusGO:0050832480.014
acylglycerol homeostasisGO:0055090190.014
regulation of mitotic cell cycleGO:00073461900.014
negative regulation of rna biosynthetic processGO:19026792400.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
alcohol metabolic processGO:0006066250.014
very long chain fatty acid metabolic processGO:000003840.014
intracellular signal transductionGO:00355563000.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
compound eye photoreceptor cell differentiationGO:00017511400.013
developmental programmed cell deathGO:00106231380.013
mitotic nuclear divisionGO:00070672130.013
modification dependent protein catabolic processGO:0019941780.013
regulation of catabolic processGO:00098941700.013
mitotic cytokinesisGO:0000281500.013
response to nutrient levelsGO:00316671140.013
cellular protein catabolic processGO:0044257830.013
hindbrain developmentGO:003090220.013
protein complex assemblyGO:00064612000.013
positive regulation of cell motilityGO:200014730.013
glycoprotein biosynthetic processGO:0009101410.013
anatomical structure homeostasisGO:0060249970.013
male gamete generationGO:00482322010.013
protein localizationGO:00081042840.013
oocyte constructionGO:00073081120.013
negative regulation of cell developmentGO:0010721620.013
cellular macromolecular complex assemblyGO:00346221530.013
pheromone biosynthetic processGO:004281130.013
steroid catabolic processGO:000670610.013
response to fungusGO:0009620500.013
small gtpase mediated signal transductionGO:0007264880.013
triglyceride homeostasisGO:0070328180.013
photoreceptor cell differentiationGO:00465301700.013
cellular amide metabolic processGO:0043603800.013
regulation of gene expression epigeneticGO:00400291280.013
adult locomotory behaviorGO:0008344760.013
monocarboxylic acid metabolic processGO:0032787290.013
regulation of epithelial cell proliferationGO:005067840.013
chromatin modificationGO:00165681470.013
oocyte axis specificationGO:00073091080.013
endomembrane system organizationGO:00102561190.013
regulation of programmed cell deathGO:00430671520.013
intracellular transportGO:00469072280.013
benzene containing compound metabolic processGO:004253730.012
salivary gland histolysisGO:0035070880.012
regulation of cellular amine metabolic processGO:003323830.012
ras protein signal transductionGO:0007265880.012
heterocycle catabolic processGO:00467001660.012
regulation of hydrolase activityGO:0051336970.012
rna processingGO:00063961470.012
maternal determination of anterior posterior axis embryoGO:0008358740.012
response to nitrogen compoundGO:1901698900.012
protein catabolic processGO:00301631010.012
secretion by cellGO:00329401010.012
extracellular matrix organizationGO:0030198320.012
rhabdomere developmentGO:0042052380.012
regulation of cell cycle processGO:00105641810.012
cell cycle checkpointGO:0000075950.012
mesenchymal cell differentiationGO:004876210.012
response to woundingGO:0009611940.012
dorsal ventral axis specificationGO:0009950660.012
multicellular organismal agingGO:00102591400.012
regulation of apoptotic processGO:00429811300.012
small molecule biosynthetic processGO:0044283370.012
proteoglycan metabolic processGO:0006029100.012
cellular nitrogen compound catabolic processGO:00442701650.012
sensory perception of chemical stimulusGO:00076061160.012
regulation of cellular amino acid metabolic processGO:000652100.012
xenobiotic catabolic processGO:004217810.012
aromatic compound catabolic processGO:00194391660.012
regulation of cellular ketone metabolic processGO:001056530.012
phosphate ion transportGO:000681740.012
sensory perception of smellGO:0007608800.012
response to glucoseGO:000974920.012
regulation of immune effector processGO:0002697520.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
mitotic sister chromatid segregationGO:0000070870.012
extracellular structure organizationGO:0043062460.012
regulation of phosphorus metabolic processGO:00511742100.012
rna localizationGO:00064031150.011
heparan sulfate proteoglycan biosynthetic processGO:0015012100.011
lipid biosynthetic processGO:0008610460.011
oocyte differentiationGO:00099941450.011
response to decreased oxygen levelsGO:0036293580.011
regulation of cellular localizationGO:00603411360.011
peptidyl amino acid modificationGO:00181931050.011
organic cyclic compound catabolic processGO:19013611680.011
positive regulation of cellular amine metabolic processGO:003324000.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
lipid localizationGO:0010876540.011
zymogen activationGO:0031638200.011
mitotic cell cycle checkpointGO:0007093880.011
cytoplasm organizationGO:0007028640.011
ribonucleotide metabolic processGO:00092591450.011
morphogenesis of embryonic epitheliumGO:0016331940.011
regulation of organelle organizationGO:00330431960.011
axon developmentGO:00615642970.011
response to calcium ionGO:005159210.011
regulation of intracellular signal transductionGO:19025312360.011
axon guidanceGO:00074112330.011
dna packagingGO:0006323910.011
chromatin remodelingGO:0006338720.011
regulation of organ growthGO:0046620420.011
ovarian follicle cell developmentGO:00307072480.011
digestive tract morphogenesisGO:00485461270.011
g protein coupled receptor signaling pathwayGO:00071861360.011
negative regulation of cell cycle processGO:00109481090.011
negative regulation of mitotic cell cycleGO:00459301090.011
dorsal ventral pattern formationGO:00099531330.011
salt aversionGO:003519930.011
cell projection assemblyGO:0030031940.011
retina development in camera type eyeGO:006004140.011
mitotic dna integrity checkpointGO:0044774750.011
organonitrogen compound biosynthetic processGO:19015661170.011
autophagyGO:00069141080.011
negative regulation of cellular protein metabolic processGO:0032269850.011
production of molecular mediator of immune responseGO:0002440460.011
organ growthGO:0035265560.011
negative regulation of cell cycle phase transitionGO:19019881030.011
neuron projection guidanceGO:00974852410.011
cilium assemblyGO:0042384380.011
apoptotic processGO:00069151590.011
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.011
positive regulation of cellular catabolic processGO:0031331950.011
protein heterooligomerizationGO:005129140.011
limb developmentGO:006017310.011
mesenchymal cell developmentGO:001403110.011
response to starvationGO:0042594970.011
cell maturationGO:00484691440.011
negative regulation of protein metabolic processGO:0051248850.011
negative regulation of defense responseGO:0031348350.011
response to oxygen levelsGO:0070482590.011
cell growthGO:00160491080.011
cilium organizationGO:0044782410.011
chemosensory behaviorGO:00076351060.011
axonogenesisGO:00074092900.011
detection of stimulus involved in sensory perceptionGO:0050906920.011
positive regulation of catabolic processGO:00098961050.011
proteasomal protein catabolic processGO:0010498590.011
sensory organ morphogenesisGO:00905962600.011
cellular homeostasisGO:0019725800.011
dna integrity checkpointGO:0031570810.011
regulation of antimicrobial peptide productionGO:0002784440.011
negative regulation of transcription dna templatedGO:00458922370.011
vesicle organizationGO:0016050440.010
wnt signaling pathwayGO:0016055980.010
tube morphogenesisGO:00352391910.010
peptidyl proline hydroxylationGO:001951110.010
central nervous system developmentGO:00074172010.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
negative regulation of gene expression epigeneticGO:0045814770.010
organonitrogen compound catabolic processGO:19015651280.010
positive regulation of response to external stimulusGO:0032103440.010
response to inorganic substanceGO:0010035440.010
organophosphate metabolic processGO:00196371950.010
cellular response to biotic stimulusGO:007121640.010
meiotic cell cycleGO:00513211710.010
heparan sulfate proteoglycan metabolic processGO:0030201100.010
response to organophosphorusGO:004668320.010
regulation of epithelial cell differentiationGO:003085640.010
single organism cellular localizationGO:19025801800.010
muscle adaptationGO:004350010.010
regulation of cellular component biogenesisGO:00440872010.010
hormone catabolic processGO:004244730.010
localization of cellGO:00516742570.010
eye photoreceptor cell developmentGO:0042462810.010
pyridine containing compound metabolic processGO:007252430.010

Spn77Bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
integumentary system diseaseDOID:1600.101
disease of anatomical entityDOID:700.101
hypotrichosisDOID:453500.101
hair diseaseDOID:42100.101
familial hyperlipidemiaDOID:116800.059
inherited metabolic disorderDOID:65500.059
disease of metabolismDOID:001466700.059
lipid metabolism disorderDOID:314600.059
familial combined hyperlipidemiaDOID:1380900.059
carbohydrate metabolism diseaseDOID:005001300.045
glucose metabolism diseaseDOID:419400.045
acquired metabolic diseaseDOID:006015800.045
diabetes mellitusDOID:935100.045
type 2 diabetes mellitusDOID:935200.037
familial hypertriglyceridemiaDOID:005052700.036
familial lipoprotein lipase deficiencyDOID:1411800.031
nervous system diseaseDOID:86300.014
sensory system diseaseDOID:005015500.012
eye and adnexa diseaseDOID:149200.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
eye diseaseDOID:561400.010