Drosophila melanogaster

126 known processes

Hsf (Dmel_CG5748)

Heat shock factor

(Aliases: CG5748,Dmel\CG5748,HSF,l(2)03091,dHSF,DmHSF,hsf,Dm-Hsf,D-HSF)

Hsf biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heterochromatin organizationGO:0070828250.923
chromosome organizationGO:00512763600.867
learning or memoryGO:00076111410.838
immune system processGO:00023763470.833
Worm
cognitionGO:00508901410.774
regulation of multi organism processGO:00439001310.765
defense response to other organismGO:00985422250.731
negative regulation of cellular metabolic processGO:00313243820.720
negative regulation of gene expressionGO:00106293870.707
axon developmentGO:00615642970.658
neuron projection guidanceGO:00974852410.656
establishment of localization in cellGO:00516494020.632
multi organism reproductive behaviorGO:00447051210.591
response to other organismGO:00517072930.579
cell divisionGO:00513012480.576
regulation of defense responseGO:00313471020.546
reproductive behaviorGO:00190981220.516
negative regulation of response to stimulusGO:00485852580.502
Yeast
taxisGO:00423303040.498
immune responseGO:00069552460.496
Worm
positive regulation of signal transductionGO:00099672230.487
appendage morphogenesisGO:00351073970.478
lipid metabolic processGO:00066291210.476
regulation of immune system processGO:00026821760.460
negative regulation of signalingGO:00230572190.438
Yeast
meiotic nuclear divisionGO:00071261510.436
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.417
morphogenesis of an epitheliumGO:00020092760.415
developmental maturationGO:00217001720.403
regulation of transportGO:00510491810.388
positive regulation of signalingGO:00230562430.379
positive regulation of protein metabolic processGO:00512471280.376
single organism intracellular transportGO:19025822070.367
protein modification processGO:00362114380.363
Mouse
multicellular organismal agingGO:00102591400.351
Worm
meiotic cell cycleGO:00513211710.347
Mouse
multicellular organismal reproductive behaviorGO:00330571100.345
epithelial cell developmentGO:00020642740.343
dna metabolic processGO:00062592270.340
regulation of multicellular organismal developmentGO:20000264140.337
regulation of protein metabolic processGO:00512462560.337
negative regulation of signal transductionGO:00099682060.334
Yeast
homeostatic processGO:00425921990.326
regulation of localizationGO:00328792750.320
chemotaxisGO:00069352490.318
regulation of cell cycle processGO:00105641810.307
Mouse
regulation of cell differentiationGO:00455953020.307
regulation of response to stressGO:00801342000.305
negative regulation of cellular biosynthetic processGO:00313272770.301
embryo development ending in birth or egg hatchingGO:00097921520.294
Mouse
positive regulation of response to stimulusGO:00485843230.287
oocyte developmentGO:00485991240.283
regulation of reproductive processGO:2000241540.278
muscle structure developmentGO:00610612240.266
embryonic pattern specificationGO:00098801740.261
negative regulation of cell communicationGO:00106482230.260
Yeast
cellular protein modification processGO:00064644380.256
Mouse
cell motilityGO:00488702510.253
positive regulation of cell communicationGO:00106472500.253
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.249
macromolecular complex assemblyGO:00650032560.245
Yeast
oocyte differentiationGO:00099941450.244
innate immune responseGO:00450871440.243
Worm
defense responseGO:00069523000.241
developmental growthGO:00485892800.239
Mouse Worm
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.232
cellular response to organic substanceGO:00713101320.230
response to external biotic stimulusGO:00432072930.219
synaptic transmissionGO:00072682880.208
axon guidanceGO:00074112330.205
axonogenesisGO:00074092900.203
agingGO:00075681430.200
Worm
central nervous system developmentGO:00074172010.197
protein complex biogenesisGO:00702712010.194
Yeast
regulation of immune responseGO:00507761180.193
deathGO:00162652840.191
response to biotic stimulusGO:00096072940.191
organelle localizationGO:00516401480.190
response to bacteriumGO:00096171980.189
single organism biosynthetic processGO:00447112060.183
positive regulation of cellular protein metabolic processGO:00322701180.164
positive regulation of immune responseGO:0050778630.164
positive regulation of transportGO:0051050920.160
positive regulation of multicellular organism growthGO:0040018210.160
Mouse Worm
imaginal disc derived appendage developmentGO:00487373990.158
apoptotic processGO:00069151590.156
growthGO:00400073590.156
Mouse Worm
positive regulation of multicellular organismal processGO:00512401430.154
Mouse Worm
cellular response to chemical stimulusGO:00708871990.154
sensory organ morphogenesisGO:00905962600.151
small molecule metabolic processGO:00442813050.151
regulation of transcription from rna polymerase ii promoterGO:00063573780.147
chromatin organizationGO:00063252070.142
negative regulation of immune system processGO:0002683500.141
positive regulation of nitrogen compound metabolic processGO:00511733540.135
regulation of apoptotic processGO:00429811300.135
regulation of organelle organizationGO:00330431960.130
blastoderm segmentationGO:00073501590.130
hemopoiesisGO:0030097460.127
macromolecule catabolic processGO:00090571610.125
dendrite morphogenesisGO:00488131990.124
regulation of programmed cell deathGO:00430671520.123
regulation of cell proliferationGO:00421271630.120
Mouse
purine ribonucleotide catabolic processGO:00091541090.120
locomotory behaviorGO:00076261760.118
cell maturationGO:00484691440.117
regulation of cell developmentGO:00602842150.117
dendrite developmentGO:00163582040.116
response to radiationGO:00093141550.116
anterior posterior axis specification embryoGO:00085951030.114
developmental programmed cell deathGO:00106231380.114
response to virusGO:0009615280.112
multi multicellular organism processGO:00447061230.111
Mouse
negative regulation of biosynthetic processGO:00098902770.110
carboxylic acid metabolic processGO:0019752920.110
regulation of mitotic cell cycleGO:00073461900.110
regulation of cellular protein metabolic processGO:00322682430.107
nuclear divisionGO:00002803320.106
Mouse
phosphorylationGO:00163102940.104
Mouse
protein localizationGO:00081042840.104
catabolic processGO:00090564090.102
organophosphate metabolic processGO:00196371950.099
regulation of anatomical structure morphogenesisGO:00226032420.098
muscle organ developmentGO:00075171270.097
nucleoside phosphate catabolic processGO:19012921100.096
negative regulation of developmental processGO:00510932010.096
immune system developmentGO:0002520570.096
regulation of cell deathGO:00109411730.094
cell proliferationGO:00082832990.093
Mouse
vesicle mediated transportGO:00161923810.092
Worm
cell deathGO:00082192790.092
oocyte constructionGO:00073081120.091
regulation of intracellular signal transductionGO:19025312360.089
Yeast
defense response to virusGO:0051607230.088
rhodopsin mediated signaling pathwayGO:0016056210.087
tube developmentGO:00352952440.087
transcription from rna polymerase ii promoterGO:00063663680.085
oocyte axis specificationGO:00073091080.084
multi organism behaviorGO:00517051750.083
neurological system processGO:00508773580.081
camera type eye developmentGO:004301040.080
Zebrafish
cell cycle dna replicationGO:0044786230.080
segmentationGO:00352822070.080
epithelial cell morphogenesis involved in gastrulationGO:000338170.079
regulation of cell cycleGO:00517262910.079
Mouse
regulation of defense response to virus by hostGO:0050691100.078
protein catabolic processGO:00301631010.078
determination of adult lifespanGO:00083401370.077
Worm
negative regulation of macromolecule biosynthetic processGO:00105582700.077
organophosphate catabolic processGO:00464341120.076
regulation of dna metabolic processGO:0051052340.075
regulation of establishment of protein localizationGO:0070201610.072
localization of cellGO:00516742570.072
positive regulation of defense responseGO:0031349590.069
muscle fiber developmentGO:0048747120.068
eye morphogenesisGO:00485922600.067
establishment of tissue polarityGO:0007164870.067
spindle organizationGO:00070512530.067
wing disc morphogenesisGO:00074723440.067
protein complex assemblyGO:00064612000.067
Yeast
positive regulation of immune system processGO:0002684680.067
cell growthGO:00160491080.066
meiotic cell cycle processGO:19030461320.064
negative regulation of cell deathGO:0060548810.064
gliogenesisGO:0042063800.063
cellular catabolic processGO:00442483720.063
regulation of protein localizationGO:0032880760.063
regulation of cellular localizationGO:00603411360.063
single organism behaviorGO:00447083910.062
tube morphogenesisGO:00352391910.061
tissue morphogenesisGO:00487292970.061
digestive tract developmentGO:00485651490.060
posttranscriptional regulation of gene expressionGO:00106081450.058
regulation of proteolysisGO:0030162870.058
positive regulation of cellular biosynthetic processGO:00313283160.058
positive regulation of macromolecule metabolic processGO:00106044050.057
chromatin modificationGO:00165681470.057
membrane organizationGO:00610241120.056
positive regulation of hydrolase activityGO:0051345780.056
negative regulation of cell differentiationGO:00455961430.056
regulation of synaptic transmissionGO:0050804690.055
positive regulation of rna biosynthetic processGO:19026802660.055
regulation of behaviorGO:0050795750.054
striated muscle cell developmentGO:0055002500.053
regulation of catabolic processGO:00098941700.053
intracellular transportGO:00469072280.052
positive regulation of catalytic activityGO:00430851180.052
positive regulation of cellular component organizationGO:00511301560.051
cellular component disassemblyGO:0022411460.051
organic substance catabolic processGO:19015753080.050
regulation of phosphorus metabolic processGO:00511742100.049
oxoacid metabolic processGO:00434361030.049
hematopoietic or lymphoid organ developmentGO:0048534570.049
regulation of cellular component sizeGO:0032535980.048
epithelial cell differentiationGO:00308553220.048
ribonucleoside triphosphate metabolic processGO:00091991190.048
cell migrationGO:00164772380.047
intracellular signal transductionGO:00355563000.047
Yeast
negative regulation of rna metabolic processGO:00512532510.046
heart developmentGO:0007507820.046
dna conformation changeGO:00711031050.046
endomembrane system organizationGO:00102561190.046
negative regulation of intracellular signal transductionGO:1902532570.046
Yeast
negative regulation of nucleobase containing compound metabolic processGO:00459342610.046
regulation of molecular functionGO:00650092170.046
regulation of response to external stimulusGO:00321011150.045
ribonucleoprotein complex subunit organizationGO:0071826280.044
organic acid metabolic processGO:00060821030.042
defense response to bacteriumGO:00427421780.042
regulation of meiosisGO:004002030.042
regulation of innate immune responseGO:0045088710.042
oocyte maturationGO:000155630.041
gene silencingGO:00164581380.041
actin filament based processGO:00300292200.041
response to organic substanceGO:00100332840.040
regulation of developmental growthGO:00486381740.040
Mouse Worm
regulation of sequence specific dna binding transcription factor activityGO:0051090120.040
endosomal transportGO:0016197440.039
protein transportGO:00150311550.039
cellular response to oxygen containing compoundGO:1901701790.039
imaginal disc derived appendage morphogenesisGO:00351143950.039
regulation of protein transportGO:0051223570.038
response to oxygen containing compoundGO:19017002000.038
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.038
purine ribonucleoside triphosphate metabolic processGO:00092051190.038
regulation of cellular catabolic processGO:00313291570.037
organic substance transportGO:00717022570.037
positive regulation of macromolecule biosynthetic processGO:00105572830.036
rhythmic processGO:00485111060.036
regulation of phosphatase activityGO:001092130.036
organelle assemblyGO:00709251980.035
myotube cell developmentGO:001490430.035
negative regulation of phosphatase activityGO:001092330.035
positive regulation of developmental processGO:00510941430.035
Mouse Worm
regulation of nurse cell apoptotic processGO:004547790.035
negative regulation of wnt signaling pathwayGO:0030178280.034
compound eye retinal cell programmed cell deathGO:0046667230.034
response to woundingGO:0009611940.034
establishment of protein localizationGO:00451841630.034
mrna splicing via spliceosomeGO:0000398730.033
proteolysisGO:00065081920.033
negative regulation of programmed cell deathGO:0043069720.032
chromatin assemblyGO:0031497480.032
positive regulation of cellular catabolic processGO:0031331950.032
intrinsic apoptotic signaling pathwayGO:0097193160.032
actin cytoskeleton organizationGO:00300362060.032
response to extracellular stimulusGO:00099911160.031
negative regulation of apoptotic processGO:0043066630.030
male gamete generationGO:00482322010.030
Mouse
ribonucleoside triphosphate catabolic processGO:00092031080.030
positive regulation of biosynthetic processGO:00098913160.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
nucleoside triphosphate metabolic processGO:00091411200.029
positive regulation of phosphorus metabolic processGO:00105621390.029
regionalizationGO:00030024160.029
regulation of synaptic plasticityGO:0048167140.029
cellular response to nitrogen compoundGO:1901699510.029
response to monosaccharideGO:003428440.029
single organism catabolic processGO:00447122280.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.028
regulation of protein phosphorylationGO:0001932640.027
regulation of cell morphogenesisGO:00226041630.027
regulation of phosphate metabolic processGO:00192202100.026
regulation of secretionGO:0051046440.026
purine ribonucleoside triphosphate catabolic processGO:00092071080.026
lipid localizationGO:0010876540.026
response to abiotic stimulusGO:00096283410.026
establishment of organelle localizationGO:00516561220.026
regulation of small gtpase mediated signal transductionGO:0051056930.026
muscle cell differentiationGO:00426921030.026
germ line stem cell maintenanceGO:0030718500.026
embryonic morphogenesisGO:00485982060.026
regulation of cell shapeGO:00083601130.025
muscle cell developmentGO:0055001500.025
neuromuscular junction developmentGO:00075281490.025
regulation of catalytic activityGO:00507901850.025
positive regulation of phosphorylationGO:0042327870.025
organonitrogen compound metabolic processGO:19015643180.025
lipid homeostasisGO:0055088330.024
eye developmentGO:00016543230.024
Zebrafish
positive regulation of cellular amine metabolic processGO:003324000.024
positive regulation of behaviorGO:0048520190.024
post embryonic appendage morphogenesisGO:00351203850.024
positive regulation of transcription dna templatedGO:00458932660.024
larval developmentGO:00021641040.023
Worm
nucleoside triphosphate catabolic processGO:00091431080.023
regulation of defense response to virusGO:0050688140.023
stem cell maintenanceGO:0019827670.023
regulation of vesicle mediated transportGO:0060627590.022
secretionGO:00469031090.022
regulation of anatomical structure sizeGO:00900661630.022
protein phosphorylationGO:00064681690.022
Mouse
adult locomotory behaviorGO:0008344760.021
stress activated protein kinase signaling cascadeGO:0031098550.021
glial cell differentiationGO:0010001350.021
response to nutrient levelsGO:00316671140.021
digestive tract morphogenesisGO:00485461270.021
positive regulation of programmed cell deathGO:0043068620.021
phagocytosisGO:00069092150.020
programmed cell deathGO:00125012570.020
rna processingGO:00063961470.020
regulation of immune effector processGO:0002697520.020
cell fate determinationGO:0001709910.020
chromatin remodelingGO:0006338720.020
neuron recognitionGO:00080381010.020
stem cell divisionGO:0017145690.020
compound eye developmentGO:00487493070.020
small gtpase mediated signal transductionGO:0007264880.020
cellular nitrogen compound catabolic processGO:00442701650.019
neuroblast proliferationGO:0007405740.019
cell cycle phase transitionGO:00447701400.019
cytoplasmic transportGO:00164821300.019
dna packagingGO:0006323910.019
positive regulation of apoptotic processGO:0043065470.019
negative regulation of nitrogen compound metabolic processGO:00511722650.019
ribose phosphate metabolic processGO:00196931450.019
learningGO:0007612750.019
skeletal muscle fiber developmentGO:004874130.018
response to alcoholGO:0097305950.018
purine containing compound catabolic processGO:00725231120.018
immune effector processGO:0002252980.018
digestive system developmentGO:00551231490.018
enzyme linked receptor protein signaling pathwayGO:00071671790.018
positive regulation of rna metabolic processGO:00512542710.018
ras protein signal transductionGO:0007265880.018
compound eye morphogenesisGO:00017452490.017
positive regulation of catabolic processGO:00098961050.017
regulation of protein import into nucleusGO:0042306280.017
positive regulation of cell deathGO:0010942690.017
establishment of blood brain barrierGO:0060856160.017
mrna metabolic processGO:00160711240.017
aromatic compound catabolic processGO:00194391660.017
purine ribonucleoside catabolic processGO:00461301120.017
asymmetric cell divisionGO:0008356370.017
single organism membrane organizationGO:0044802930.017
positive regulation of developmental growthGO:0048639620.017
Mouse Worm
positive regulation of phosphate metabolic processGO:00459371390.017
nurse cell apoptotic processGO:0045476170.017
embryonic axis specificationGO:00005781070.017
neural precursor cell proliferationGO:0061351750.017
regulation of cellular amino acid metabolic processGO:000652100.017
ovipositionGO:0018991190.016
cell recognitionGO:00080371020.016
negative regulation of protein metabolic processGO:0051248850.016
regulation of embryonic developmentGO:0045995680.016
molting cycleGO:0042303560.016
ribonucleoside monophosphate metabolic processGO:0009161510.016
regulation of hydrolase activityGO:0051336970.016
intracellular receptor signaling pathwayGO:0030522190.016
actomyosin structure organizationGO:0031032560.016
germarium derived egg chamber formationGO:00072931010.016
autophagyGO:00069141080.015
regulation of cellular component biogenesisGO:00440872010.015
regulation of cell cycle phase transitionGO:19019871300.015
negative regulation of immune responseGO:0050777390.015
adult behaviorGO:00305341370.015
humoral immune responseGO:00069591170.015
tripartite regional subdivisionGO:00073511030.015
purine nucleotide catabolic processGO:00061951090.015
response to axon injuryGO:0048678120.015
mucosal immune responseGO:0002385100.015
wnt signaling pathwayGO:0016055980.015
anterior posterior pattern specificationGO:00099521360.014
regulation of protein catabolic processGO:0042176550.014
positive regulation of protein modification processGO:0031401580.014
single organism cellular localizationGO:19025801800.014
positive regulation of protein kinase activityGO:0045860250.014
eye antennal disc developmentGO:0035214600.014
protein modification by small protein conjugation or removalGO:00706471060.014
regulation of response to biotic stimulusGO:0002831630.014
matingGO:00076181200.014
nucleotide catabolic processGO:00091661090.014
positive regulation of protein phosphorylationGO:0001934340.014
ovarian follicle cell developmentGO:00307072480.014
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clusteringGO:009711320.014
stem cell proliferationGO:0072089880.014
embryonic development via the syncytial blastodermGO:00017001480.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
regulation of organ morphogenesisGO:2000027780.013
regulation of cellular response to stressGO:0080135890.013
peptidyl lysine modificationGO:0018205570.013
regulation of nucleocytoplasmic transportGO:0046822350.013
chromatin assembly or disassemblyGO:0006333520.013
regulation of membrane potentialGO:0042391350.013
circulatory system developmentGO:0072359820.013
cell cycle arrestGO:000705040.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
chorion containing eggshell formationGO:00073041050.013
protein heterooligomerizationGO:005129140.013
regulation of phosphorylationGO:00423251470.013
regulation of nucleoside metabolic processGO:0009118500.013
purine nucleoside triphosphate catabolic processGO:00091461080.013
regulation of transferase activityGO:0051338580.013
small rna loading onto riscGO:007092260.013
salivary gland morphogenesisGO:00074351450.013
heterochromatin organization involved in chromatin silencingGO:007086890.012
synaptic growth at neuromuscular junctionGO:00511241190.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
larval behaviorGO:0030537420.012
heterocycle catabolic processGO:00467001660.012
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
malpighian tubule developmentGO:0072002640.012
regulation of cell sizeGO:0008361630.012
cellular response to organic cyclic compoundGO:0071407320.012
purine nucleoside monophosphate metabolic processGO:0009126500.012
appendage developmentGO:00487364010.012
cellular response to peptide hormone stimulusGO:0071375280.012
regulation of canonical wnt signaling pathwayGO:0060828150.012
anatomical structure homeostasisGO:0060249970.011
positive regulation of cell developmentGO:0010720610.011
cation transportGO:00068121100.011
canonical wnt signaling pathwayGO:0060070210.011
neuronal action potentialGO:0019228100.011
negative regulation of cellular protein metabolic processGO:0032269850.011
vesicle localizationGO:0051648550.011
positive regulation of nucleotide catabolic processGO:0030813460.011
circadian rhythmGO:00076231050.011
cardiovascular system developmentGO:0072358820.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
regulation of hemocyte proliferationGO:0035206370.011
negative regulation of rna biosynthetic processGO:19026792400.011
stem cell differentiationGO:00488631170.011
nucleobase containing compound catabolic processGO:00346551650.011
skeletal muscle organ developmentGO:0060538480.011
open tracheal system developmentGO:00074242040.011
intracellular steroid hormone receptor signaling pathwayGO:0030518120.011
epithelial cell morphogenesisGO:0003382250.011
negative regulation of cell developmentGO:0010721620.011
positive regulation of innate immune responseGO:0045089380.011
regulation of cell growthGO:0001558430.011
asymmetric protein localization involved in cell fate determinationGO:004516790.011
gastrulationGO:0007369700.011
axon ensheathment in central nervous systemGO:003229130.010
regulation of cellular amine metabolic processGO:003323830.010
positive regulation of organelle organizationGO:0010638650.010
cellular protein localizationGO:00346131600.010
respiratory system developmentGO:00605412130.010
asymmetric stem cell divisionGO:0098722490.010
positive regulation of protein transportGO:0051222370.010
mapk cascadeGO:00001651070.010
positive regulation of bindingGO:005109940.010
detection of visible lightGO:0009584380.010
regulation of neurogenesisGO:00507671580.010
response to nitrogen compoundGO:1901698900.010

Hsf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.015
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
benign neoplasmDOID:006007200.010