Drosophila melanogaster

124 known processes

Frq1 (Dmel_CG5744)

Frequenin 1

(Aliases: HL-II,frq1,CG5744,frq,Dmel\CG5744,Frq)

Frq1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072682880.993
neuromuscular junction developmentGO:00075281490.928
neurotransmitter transportGO:0006836370.918
regulation of neurotransmitter secretionGO:0046928140.810
Fly
regulation of synapse structure and activityGO:00508031280.746
regulation of neurotransmitter levelsGO:0001505380.683
signal releaseGO:0023061490.664
regulation of synaptic transmissionGO:0050804690.622
Fly
establishment of localization in cellGO:00516494020.615
cation transportGO:00068121100.606
Rat
synapse organizationGO:00508081960.603
secretion by cellGO:00329401010.500
regulation of secretion by cellGO:1903530390.484
Rat Fly
neurotransmitter secretionGO:0007269350.466
establishment of vesicle localizationGO:0051650510.450
secretionGO:00469031090.446
synaptic growth at neuromuscular junctionGO:00511241190.439
regulation of synapse organizationGO:00508071100.386
regulation of neurotransmitter transportGO:0051588140.366
Fly
metal ion transportGO:0030001740.315
Rat
ion transmembrane transportGO:00342201220.287
Rat
regulation of transportGO:00510491810.274
Rat Fly
regulation of secretionGO:0051046440.273
Rat Fly
regulation of synaptic growth at neuromuscular junctionGO:0008582890.271
cgmp biosynthetic processGO:000618280.264
regulation of multicellular organismal developmentGO:20000264140.250
Rat
synaptic vesicle transportGO:0048489500.228
synapse assemblyGO:00074161430.224
neuromuscular synaptic transmissionGO:0007274670.218
regulation of membrane potentialGO:0042391350.215
response to abiotic stimulusGO:00096283410.195
neuron neuron synaptic transmissionGO:0007270140.192
synaptic vesicle recyclingGO:0036465280.187
regulation of synapse assemblyGO:0051963940.181
regulation of nervous system developmentGO:00519602480.167
Rat
single organism behaviorGO:00447083910.166
single organism membrane fusionGO:0044801420.163
regulation of excitatory postsynaptic membrane potentialGO:006007930.161
axonogenesisGO:00074092900.159
regulation of cell differentiationGO:00455953020.159
Rat
synaptic vesicle localizationGO:0097479530.156
ion transportGO:00068111450.151
Rat
locomotory behaviorGO:00076261760.139
vesicle mediated transportGO:00161923810.133
Rat
vitamin transportGO:005118020.121
growthGO:00400073590.117
regulation of cellular component biogenesisGO:00440872010.114
regulation of localizationGO:00328792750.113
Rat Fly
establishment of synaptic vesicle localizationGO:0097480500.112
axon developmentGO:00615642970.104
positive regulation of cgmp metabolic processGO:003082510.102
synaptic transmission glutamatergicGO:003524970.101
membrane organizationGO:00610241120.098
adult locomotory behaviorGO:0008344760.092
cellular homeostasisGO:0019725800.091
transmembrane transportGO:00550851390.091
Rat
negative regulation of cell communicationGO:00106482230.091
single organism membrane organizationGO:0044802930.087
developmental growthGO:00485892800.084
inorganic cation transmembrane transportGO:0098662610.082
Rat
regulation of cellular localizationGO:00603411360.081
Rat Fly
regulation of transmembrane transportGO:0034762270.080
Rat
multi organism behaviorGO:00517051750.078
cellular protein modification processGO:00064644380.077
neurotransmitter metabolic processGO:004213320.076
tube morphogenesisGO:00352391910.075
Zebrafish
nitrogen compound transportGO:0071705850.075
terminal button organizationGO:0072553190.072
camera type eye developmentGO:004301040.071
positive regulation of synapse assemblyGO:0051965290.070
positive regulation of synaptic transmissionGO:0050806150.069
regulation of neurogenesisGO:00507671580.064
Rat
catabolic processGO:00090564090.064
regulation of neuromuscular synaptic transmissionGO:1900073150.064
muscle structure developmentGO:00610612240.062
potassium ion transportGO:0006813200.061
positive regulation of cell communicationGO:00106472500.058
calcium ion transmembrane transportGO:0070588170.057
Rat
muscle system processGO:0003012210.057
positive regulation of signalingGO:00230562430.057
organic substance transportGO:00717022570.056
developmental maturationGO:00217001720.056
regulation of developmental growthGO:00486381740.056
eye developmentGO:00016543230.055
rhythmic excitationGO:004317910.055
small molecule metabolic processGO:00442813050.055
tube developmentGO:00352952440.054
Zebrafish
exocytosisGO:0006887280.054
Rat
chemotaxisGO:00069352490.054
homeostatic processGO:00425921990.053
regulation of terminal button organizationGO:2000331110.053
positive regulation of exocytosisGO:004592140.053
Rat
cellular macromolecule localizationGO:00707272200.052
cellular protein localizationGO:00346131600.050
acetate ester metabolic processGO:190061920.049
cellular component assembly involved in morphogenesisGO:00109271510.049
regulation of synaptic transmission glutamatergicGO:005196650.048
neuron maturationGO:0042551310.047
negative regulation of signalingGO:00230572190.047
endocytosisGO:00068973100.047
synaptic vesicle endocytosisGO:0048488280.047
rhythmic synaptic transmissionGO:006002420.046
cell maturationGO:00484691440.046
regulation of glutamate receptor signaling pathwayGO:190044910.045
vesicle localizationGO:0051648550.045
male courtship behavior veined wing extensionGO:0048065220.045
positive regulation of synaptic vesicle endocytosisGO:190024440.044
regulation of growthGO:00400082330.043
membrane depolarizationGO:005189940.043
single organism cellular localizationGO:19025801800.042
associative learningGO:0008306650.042
regulation of ion transmembrane transportGO:0034765270.042
Rat
negative regulation of response to stimulusGO:00485852580.041
positive regulation of cellular component organizationGO:00511301560.041
cell recognitionGO:00080371020.041
regulation of cell developmentGO:00602842150.040
Rat
positive regulation of transportGO:0051050920.040
Rat
divalent inorganic cation transportGO:0072511300.040
Rat
neuron projection guidanceGO:00974852410.039
endoplasmic reticulum organizationGO:0007029130.038
single organism catabolic processGO:00447122280.036
cell projection assemblyGO:0030031940.035
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.035
positive regulation of synaptic vesicle recyclingGO:190342340.034
acetylcholine metabolic processGO:000829120.034
muscle cell differentiationGO:00426921030.034
response to biotic stimulusGO:00096072940.033
response to radiationGO:00093141550.033
regulation of vesicle mediated transportGO:0060627590.033
Rat
regulation of cell projection organizationGO:0031344920.032
Rat
carbohydrate derivative metabolic processGO:19011352170.032
membrane fusionGO:0061025420.032
organelle assemblyGO:00709251980.032
organonitrogen compound metabolic processGO:19015643180.031
positive regulation of developmental processGO:00510941430.031
protein localizationGO:00081042840.031
axon guidanceGO:00074112330.031
striated muscle cell developmentGO:0055002500.031
programmed cell deathGO:00125012570.031
organelle localizationGO:00516401480.031
positive regulation of synaptic transmission glutamatergicGO:005196830.030
neuron recognitionGO:00080381010.030
organic substance catabolic processGO:19015753080.030
negative regulation of signal transductionGO:00099682060.029
nucleoside catabolic processGO:00091641120.029
phagocytosisGO:00069092150.029
purine nucleoside triphosphate catabolic processGO:00091461080.028
purine containing compound metabolic processGO:00725211550.028
macromolecular complex assemblyGO:00650032560.028
positive regulation of cellular component biogenesisGO:0044089800.028
purine ribonucleotide catabolic processGO:00091541090.028
endomembrane system organizationGO:00102561190.028
carboxylic acid metabolic processGO:0019752920.028
hindbrain developmentGO:003090220.027
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.027
nucleobase containing small molecule metabolic processGO:00550861740.027
regulation of cell proliferationGO:00421271630.027
regulation of synaptic vesicle endocytosisGO:190024270.027
synaptic vesicle exocytosisGO:0016079160.027
regionalizationGO:00030024160.026
response to external biotic stimulusGO:00432072930.026
positive regulation of purine nucleotide metabolic processGO:1900544550.026
regulation of synaptic vesicle exocytosisGO:200030030.026
regulation of embryonic pattern specificationGO:1902875270.026
establishment of protein localizationGO:00451841630.025
nucleoside phosphate catabolic processGO:19012921100.025
monovalent inorganic cation transportGO:0015672400.024
single organism biosynthetic processGO:00447112060.024
anatomical structure homeostasisGO:0060249970.024
cellular amine metabolic processGO:0044106120.024
purine ribonucleotide metabolic processGO:00091501450.024
retina development in camera type eyeGO:006004140.024
cellular response to organic substanceGO:00713101320.023
positive regulation of response to stimulusGO:00485843230.023
protein heterooligomerizationGO:005129140.023
regulation of ion transportGO:0043269390.023
Rat
chromatin modificationGO:00165681470.023
regulation of synaptic activityGO:006002590.023
membrane biogenesisGO:004409180.023
sensory organ morphogenesisGO:00905962600.023
Zebrafish
dendrite developmentGO:00163582040.023
purine nucleotide metabolic processGO:00061631460.022
cell proliferationGO:00082832990.022
purine ribonucleoside triphosphate metabolic processGO:00092051190.022
response to mechanical stimulusGO:0009612280.022
axis specificationGO:00097981670.022
positive regulation of cell deathGO:0010942690.022
mushroom body developmentGO:0016319700.022
organophosphate metabolic processGO:00196371950.022
immune system processGO:00023763470.022
embryonic pattern specificationGO:00098801740.022
myotube cell developmentGO:001490430.021
chromatin organizationGO:00063252070.021
cellular response to lipopolysaccharideGO:007122230.021
positive regulation of molecular functionGO:00440931360.021
carbohydrate derivative catabolic processGO:19011361180.021
intracellular signal transductionGO:00355563000.021
Rat
regulation of dendrite developmentGO:0050773370.021
positive regulation of cell migrationGO:003033520.021
protein depolymerizationGO:0051261310.020
positive regulation of protein metabolic processGO:00512471280.020
organonitrogen compound catabolic processGO:19015651280.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
transcription from rna polymerase ii promoterGO:00063663680.020
cognitionGO:00508901410.020
sarcomere organizationGO:0045214260.020
purine ribonucleoside metabolic processGO:00461281270.020
sensory perception of soundGO:0007605560.020
segmentationGO:00352822070.020
positive regulation of catalytic activityGO:00430851180.019
positive regulation of biosynthetic processGO:00098913160.019
cyclic nucleotide metabolic processGO:0009187280.019
appendage developmentGO:00487364010.019
regulation of cell projection assemblyGO:0060491300.019
organic acid metabolic processGO:00060821030.019
cellular protein complex disassemblyGO:0043624350.019
ribonucleoside triphosphate catabolic processGO:00092031080.019
regulation of phosphorus metabolic processGO:00511742100.019
adult behaviorGO:00305341370.019
cellular catabolic processGO:00442483720.019
cation transmembrane transportGO:0098655880.018
Rat
carbohydrate derivative biosynthetic processGO:1901137850.018
positive regulation of cgmp biosynthetic processGO:003082810.018
camera type eye morphogenesisGO:004859320.018
regulation of cytoskeleton organizationGO:0051493890.018
regulation of behaviorGO:0050795750.018
learningGO:0007612750.018
single organism carbohydrate metabolic processGO:0044723720.018
agingGO:00075681430.018
regulation of wnt signaling pathwayGO:0030111680.018
positive regulation of multicellular organismal processGO:00512401430.018
positive regulation of neurotransmitter secretionGO:000195620.018
positive regulation of nervous system developmentGO:0051962690.018
wnt signaling pathwayGO:0016055980.017
regulation of cell deathGO:00109411730.017
cell growthGO:00160491080.017
peripheral nervous system developmentGO:0007422520.017
regulation of system processGO:0044057360.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
learning or memoryGO:00076111410.017
neuroblast proliferationGO:0007405740.017
establishment of organelle localizationGO:00516561220.017
action potentialGO:0001508130.017
regulation of synaptic plasticityGO:0048167140.017
protein complex assemblyGO:00064612000.017
negative regulation of multicellular organismal processGO:00512411420.017
branching involved in open tracheal system developmentGO:0060446450.017
striated muscle cell differentiationGO:0051146900.017
response to nutrient levelsGO:00316671140.017
dendrite morphogenesisGO:00488131990.017
cell deathGO:00082192790.017
chemical homeostasisGO:0048878920.017
negative regulation of developmental processGO:00510932010.017
regulation of anatomical structure sizeGO:00900661630.016
purine ribonucleoside catabolic processGO:00461301120.016
skeletal muscle fiber developmentGO:004874130.016
positive regulation of growthGO:0045927750.016
proteolysisGO:00065081920.016
positive regulation of phosphate metabolic processGO:00459371390.016
positive regulation of apoptotic signaling pathwayGO:200123540.016
cell adhesionGO:00071551360.016
blastoderm segmentationGO:00073501590.016
positive regulation of programmed cell deathGO:0043068620.016
chromatin remodelingGO:0006338720.016
neuron projection extensionGO:1990138320.015
nuclear divisionGO:00002803320.015
nucleoside triphosphate catabolic processGO:00091431080.015
protein complex biogenesisGO:00702712010.015
muscle cell developmentGO:0055001500.015
photoreceptor cell developmentGO:0042461960.015
forebrain developmentGO:003090020.015
regulation of multi organism processGO:00439001310.015
positive regulation of signal transductionGO:00099672230.015
photoreceptor cell differentiationGO:00465301700.015
regulation of defense responseGO:00313471020.015
negative regulation of synapse assemblyGO:0051964390.015
axon extensionGO:0048675320.015
nucleoside metabolic processGO:00091161270.015
positive regulation of cell differentiationGO:0045597640.015
dna metabolic processGO:00062592270.014
regulation of phosphate metabolic processGO:00192202100.014
heterocycle catabolic processGO:00467001660.014
spermatogenesisGO:00072832000.014
intracellular protein transportGO:00068861040.014
cellular amino acid metabolic processGO:0006520610.014
synapse maturationGO:006007470.014
protein catabolic processGO:00301631010.014
response to monosaccharideGO:003428440.014
divalent metal ion transportGO:0070838260.014
Rat
cellular nitrogen compound catabolic processGO:00442701650.014
kidney developmentGO:000182230.014
appendage morphogenesisGO:00351073970.014
ribonucleoside metabolic processGO:00091191270.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
cellular potassium ion transportGO:0071804180.014
multicellular organismal agingGO:00102591400.014
ribose phosphate metabolic processGO:00196931450.014
regulation of mitotic cell cycleGO:00073461900.014
ribonucleoside catabolic processGO:00424541120.014
glycosyl compound metabolic processGO:19016571270.014
apoptotic processGO:00069151590.014
detection of light stimulusGO:0009583580.014
body morphogenesisGO:001017120.014
oxoacid metabolic processGO:00434361030.014
epithelial tube morphogenesisGO:0060562880.014
regulation of cell cycle processGO:00105641810.014
cytoplasmic transportGO:00164821300.013
response to organic substanceGO:00100332840.013
taxisGO:00423303040.013
multicellular organism growthGO:0035264460.013
positive regulation of phosphorus metabolic processGO:00105621390.013
motor neuron axon guidanceGO:0008045580.013
nucleotide metabolic processGO:00091171610.013
organelle fissionGO:00482853400.013
aromatic compound catabolic processGO:00194391660.013
purine nucleoside catabolic processGO:00061521120.013
ribonucleotide metabolic processGO:00092591450.013
calcium ion transportGO:0006816240.013
Rat
circulatory system processGO:0003013370.013
muscle organ developmentGO:00075171270.013
positive regulation of organelle organizationGO:0010638650.013
stem cell developmentGO:0048864790.013
cellular biogenic amine catabolic processGO:004240210.013
embryonic organ developmentGO:0048568500.013
Zebrafish
regulation of endocytosisGO:0030100370.013
maternal determination of anterior posterior axis embryoGO:0008358740.012
response to lipopolysaccharideGO:003249640.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of immune system processGO:00026821760.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
mesenchymal cell developmentGO:001403110.012
embryonic axis specificationGO:00005781070.012
protein modification by small protein conjugation or removalGO:00706471060.012
post embryonic appendage morphogenesisGO:00351203850.012
response to toxic substanceGO:0009636220.012
positive regulation of catabolic processGO:00098961050.012
rna processingGO:00063961470.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
neuron remodelingGO:0016322290.012
mitotic nuclear divisionGO:00070672130.012
stem cell proliferationGO:0072089880.012
courtship behaviorGO:0007619680.012
bmp signaling pathwayGO:0030509270.012
muscle contractionGO:0006936130.012
eye morphogenesisGO:00485922600.012
cytokinesisGO:0000910900.012
pattern recognition receptor signaling pathwayGO:000222120.012
isoprenoid transportGO:004686420.012
actin filament based processGO:00300292200.012
response to hexoseGO:000974630.012
positive regulation of hydrolase activityGO:0051345780.012
detection of stimulusGO:00516061560.012
response to other organismGO:00517072930.012
vesicle organizationGO:0016050440.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
larval locomotory behaviorGO:0008345270.012
potassium ion transmembrane transportGO:0071805180.011
skin developmentGO:0043588650.011
organic cyclic compound catabolic processGO:19013611680.011
posttranscriptional regulation of gene expressionGO:00106081450.011
positive regulation of purine nucleotide biosynthetic processGO:1900373100.011
presynaptic membrane organizationGO:009709040.011
neuron cell cell adhesionGO:000715810.011
regulation of intracellular signal transductionGO:19025312360.011
neural precursor cell proliferationGO:0061351750.011
regulation of synaptic vesicle transportGO:1902803100.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633990.011
filopodium assemblyGO:0046847330.011
regulation of programmed cell deathGO:00430671520.011
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
cellular response to chemical stimulusGO:00708871990.011
positive regulation of cell motilityGO:200014730.011
cranial nerve developmentGO:002154510.011
deathGO:00162652840.011
visual learningGO:000854240.011
positive regulation of nucleotide biosynthetic processGO:0030810100.011
dna packagingGO:0006323910.011
striated muscle contractionGO:000694150.011
regulation of gene expression epigeneticGO:00400291280.011
terpenoid transportGO:004686520.011
regulation of catabolic processGO:00098941700.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
gtp catabolic processGO:0006184720.011
regulation of organelle organizationGO:00330431960.011
synaptic vesicle fusion to presynaptic membraneGO:003162970.011
chromosome organizationGO:00512763600.010
open tracheal system developmentGO:00074242040.010
actin filament based movementGO:0030048260.010
biological adhesionGO:00226101380.010
regulation of protein kinase a signalingGO:001073820.010
matingGO:00076181200.010
single organismal cell cell adhesionGO:0016337450.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
positive regulation of cell developmentGO:0010720610.010
regulation of hydrolase activityGO:0051336970.010
compound eye developmentGO:00487493070.010
organelle fusionGO:0048284460.010
protein transportGO:00150311550.010
positive regulation of cellular protein metabolic processGO:00322701180.010
regulation of cellular ketone metabolic processGO:001056530.010
limb developmentGO:006017310.010
imaginal disc derived wing morphogenesisGO:00074763370.010
necrotic cell deathGO:007026510.010
regulation of innate immune responseGO:0045088710.010
purine containing compound catabolic processGO:00725231120.010

Frq1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.055
cardiovascular system diseaseDOID:128700.024
vascular diseaseDOID:17800.017
artery diseaseDOID:005082800.017
disease of metabolismDOID:001466700.015
diabetes mellitusDOID:935100.012
carbohydrate metabolism diseaseDOID:005001300.012
glucose metabolism diseaseDOID:419400.012
acquired metabolic diseaseDOID:006015800.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
organ system cancerDOID:005068600.011