IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG4335 (Dmel_CG4335)

CG4335 gene product from transcript CG4335-RA

(Aliases: Dmel\CG4335)

Entrez: 42421
FLYBASE: FBgn0038795
UniProtKB: Q9VDM7

Process Predictions
Disease Predictions

CG4335 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
spermatid differentiation	GO:0048515	114	0.190
spermatogenesis	GO:0007283	200	0.166
mating	GO:0007618	120	0.135
cilium morphogenesis	GO:0060271	39	0.128
biological adhesion	GO:0022610	138	0.120
response to biotic stimulus	GO:0009607	294	0.110
proteolysis	GO:0006508	192	0.106
axon guidance	GO:0007411	233	0.099
response to light stimulus	GO:0009416	124	0.098
multicellular organismal reproductive behavior	GO:0033057	110	0.098
response to external biotic stimulus	GO:0043207	293	0.095
multi organism behavior	GO:0051705	175	0.093
organic substance catabolic process	GO:1901575	308	0.085
sensory organ morphogenesis	GO:0090596	260	0.081
male gamete generation	GO:0048232	201	0.080
mating behavior	GO:0007617	106	0.076
organic substance transport	GO:0071702	257	0.071
catabolic process	GO:0009056	409	0.069
small molecule metabolic process	GO:0044281	305	0.066
spermatid development	GO:0007286	98	0.065
compound eye morphogenesis	GO:0001745	249	0.064
organonitrogen compound catabolic process	GO:1901565	128	0.064
wing disc morphogenesis	GO:0007472	344	0.062
taxis	GO:0042330	304	0.057
choline catabolic process	GO:0042426	1	0.053
kidney development	GO:0001822	3	0.051
axon development	GO:0061564	297	0.051
organonitrogen compound metabolic process	GO:1901564	318	0.051
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.050
negative regulation of female receptivity	GO:0007621	14	0.049
chemotaxis	GO:0006935	249	0.048
reproductive behavior	GO:0019098	122	0.048
cellular catabolic process	GO:0044248	372	0.048
axonogenesis	GO:0007409	290	0.044
defense response	GO:0006952	300	0.043
neuron recognition	GO:0008038	101	0.043
open tracheal system development	GO:0007424	204	0.043
compound eye development	GO:0048749	307	0.042
heart development	GO:0007507	82	0.041
acetylcholine metabolic process	GO:0008291	2	0.041
post embryonic appendage morphogenesis	GO:0035120	385	0.039
cell junction assembly	GO:0034329	42	0.039
lateral inhibition	GO:0046331	206	0.039
appendage development	GO:0048736	401	0.039
neurotransmitter catabolic process	GO:0042135	1	0.039
chromosome segregation	GO:0007059	157	0.038
synaptic transmission	GO:0007268	288	0.038
eye development	GO:0001654	323	0.036
response to other organism	GO:0051707	293	0.036
imaginal disc derived wing morphogenesis	GO:0007476	337	0.036
maintenance of location	GO:0051235	73	0.035
regulation of tube size	GO:0035150	46	0.035
peripheral nervous system development	GO:0007422	52	0.035
female meiotic division	GO:0007143	70	0.035
female mating behavior	GO:0060180	30	0.035
steroid catabolic process	GO:0006706	1	0.035
meiotic nuclear division	GO:0007126	151	0.035
regulation of neurotransmitter levels	GO:0001505	38	0.034
localization of cell	GO:0051674	257	0.034
cell recognition	GO:0008037	102	0.034
immune system process	GO:0002376	347	0.034
regulation of vesicle mediated transport	GO:0060627	59	0.034
death	GO:0016265	284	0.033
amine metabolic process	GO:0009308	12	0.033
appendage morphogenesis	GO:0035107	397	0.033
cell adhesion	GO:0007155	136	0.033
endocytosis	GO:0006897	310	0.032
regionalization	GO:0003002	416	0.032
cell death	GO:0008219	279	0.032
cell cell junction organization	GO:0045216	55	0.031
negative regulation of cell communication	GO:0010648	223	0.031
eye morphogenesis	GO:0048592	260	0.031
defense response to other organism	GO:0098542	225	0.030
response to organophosphorus	GO:0046683	2	0.030
response to temperature stimulus	GO:0009266	106	0.030
imaginal disc derived appendage development	GO:0048737	399	0.030
regulation of anatomical structure size	GO:0090066	163	0.029
organelle assembly	GO:0070925	198	0.029
columnar cuboidal epithelial cell development	GO:0002066	249	0.029
negative regulation of signal transduction	GO:0009968	206	0.029
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.029
regulation of tube architecture open tracheal system	GO:0035152	68	0.028
respiratory system development	GO:0060541	213	0.028
response to abiotic stimulus	GO:0009628	341	0.028
neuron projection guidance	GO:0097485	241	0.028
imaginal disc derived wing hair organization	GO:0035317	45	0.027
synaptic target recognition	GO:0008039	45	0.027
cell motility	GO:0048870	251	0.026
organelle fission	GO:0048285	340	0.026
pigment metabolic process involved in developmental pigmentation	GO:0043324	33	0.026
response to radiation	GO:0009314	155	0.026
detection of stimulus	GO:0051606	156	0.026
peptide metabolic process	GO:0006518	80	0.025
androgen metabolic process	GO:0008209	1	0.025
acetate ester metabolic process	GO:1900619	2	0.024
innate immune response	GO:0045087	144	0.024
organic cyclic compound catabolic process	GO:1901361	168	0.024
protein maturation	GO:0051604	71	0.024
eye pigment biosynthetic process	GO:0006726	32	0.024
response to organic substance	GO:0010033	284	0.024
cell migration	GO:0016477	238	0.024
cellular ketone metabolic process	GO:0042180	24	0.023
macromolecule catabolic process	GO:0009057	161	0.023
vitamin biosynthetic process	GO:0009110	1	0.023
salivary gland morphogenesis	GO:0007435	145	0.023
cell cell junction assembly	GO:0007043	38	0.023
regulation of catalytic activity	GO:0050790	185	0.023
septate junction assembly	GO:0019991	26	0.023
detection of chemical stimulus	GO:0009593	93	0.023
meiotic cell cycle	GO:0051321	171	0.022
transcription from rna polymerase ii promoter	GO:0006366	368	0.022
fat soluble vitamin metabolic process	GO:0006775	1	0.022
multicellular organismal aging	GO:0010259	140	0.022
response to lipopolysaccharide	GO:0032496	4	0.021
heart morphogenesis	GO:0003007	32	0.021
drinking behavior	GO:0042756	2	0.021
growth	GO:0040007	359	0.021
cellular modified amino acid metabolic process	GO:0006575	45	0.021
single organism catabolic process	GO:0044712	228	0.020
alpha amino acid metabolic process	GO:1901605	20	0.020
monocarboxylic acid transport	GO:0015718	3	0.020
phagocytosis	GO:0006909	215	0.020
chaeta development	GO:0022416	97	0.020
epithelial cell development	GO:0002064	274	0.020
amine catabolic process	GO:0009310	1	0.020
medium chain fatty acid metabolic process	GO:0051791	1	0.020
xenobiotic catabolic process	GO:0042178	1	0.020
negative regulation of cellular metabolic process	GO:0031324	382	0.020
nucleus organization	GO:0006997	45	0.020
ethanolamine containing compound metabolic process	GO:0042439	4	0.020
cellular amide metabolic process	GO:0043603	80	0.019
neurotransmitter metabolic process	GO:0042133	2	0.019
regulation of endocytosis	GO:0030100	37	0.019
amino sugar catabolic process	GO:0046348	3	0.019
non sensory hair organization	GO:0035316	47	0.018
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.018
vesicle mediated transport	GO:0016192	381	0.018
regulation of female receptivity	GO:0045924	24	0.018
mitotic spindle organization	GO:0007052	220	0.018
oxoacid metabolic process	GO:0043436	103	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
organic acid metabolic process	GO:0006082	103	0.018
body morphogenesis	GO:0010171	2	0.018
cellular response to lipopolysaccharide	GO:0071222	3	0.018
single organism biosynthetic process	GO:0044711	206	0.018
vitamin metabolic process	GO:0006766	2	0.018
lipid localization	GO:0010876	54	0.018
secretion	GO:0046903	109	0.017
male mating behavior	GO:0060179	70	0.017
dna metabolic process	GO:0006259	227	0.017
negative regulation of signaling	GO:0023057	219	0.017
nuclear division	GO:0000280	332	0.017
humoral immune response	GO:0006959	117	0.017
carbohydrate derivative metabolic process	GO:1901135	217	0.017
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.017
histolysis	GO:0007559	102	0.017
pigmentation	GO:0043473	75	0.017
chitin catabolic process	GO:0006032	3	0.017
programmed cell death	GO:0012501	257	0.017
regulation of tube size open tracheal system	GO:0035151	43	0.017
salivary gland cell autophagic cell death	GO:0035071	83	0.017
hair cell differentiation	GO:0035315	47	0.017
acetylcholine catabolic process	GO:0006581	1	0.016
tissue migration	GO:0090130	155	0.016
rhythmic process	GO:0048511	106	0.016
detection of abiotic stimulus	GO:0009582	66	0.016
ameboidal type cell migration	GO:0001667	151	0.016
cardiovascular system development	GO:0072358	82	0.016
maintenance of imaginal disc derived wing hair orientation	GO:0035321	3	0.016
regulation of molecular function	GO:0065009	217	0.016
establishment of localization in cell	GO:0051649	402	0.016
energy taxis	GO:0009453	21	0.016
pigment metabolic process involved in pigmentation	GO:0043474	33	0.016
developmental growth	GO:0048589	280	0.016
dorsal ventral axis specification	GO:0009950	66	0.016
pigment metabolic process	GO:0042440	84	0.016
detection of light stimulus	GO:0009583	58	0.016
positive regulation of hemocyte proliferation	GO:0035208	4	0.016
regulation of localization	GO:0032879	275	0.016
glucosamine containing compound catabolic process	GO:1901072	3	0.016
purine nucleoside metabolic process	GO:0042278	127	0.016
cellularization	GO:0007349	90	0.016
single organism behavior	GO:0044708	391	0.015
lipid storage	GO:0019915	38	0.015
defense response to bacterium	GO:0042742	178	0.015
female meiosis chromosome segregation	GO:0016321	33	0.015
regulation of cell cycle	GO:0051726	291	0.015
gland morphogenesis	GO:0022612	145	0.015
regulation of female receptivity post mating	GO:0046008	17	0.015
developmental pigmentation	GO:0048066	68	0.015
homeostatic process	GO:0042592	199	0.015
protein modification process	GO:0036211	438	0.015
carbohydrate derivative catabolic process	GO:1901136	118	0.015
axis specification	GO:0009798	167	0.015
cellular response to biotic stimulus	GO:0071216	4	0.015
cellular protein modification process	GO:0006464	438	0.015
salivary gland development	GO:0007431	162	0.014
positive regulation of response to stimulus	GO:0048584	323	0.014
immune effector process	GO:0002252	98	0.014
protein processing	GO:0016485	68	0.014
positive regulation of molecular function	GO:0044093	136	0.014
membrane organization	GO:0061024	112	0.014
meiotic chromosome segregation	GO:0045132	59	0.014
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
regulation of cellular localization	GO:0060341	136	0.014
antimicrobial humoral response	GO:0019730	99	0.014
cellular amine metabolic process	GO:0044106	12	0.014
detection of visible light	GO:0009584	38	0.014
cellular hormone metabolic process	GO:0034754	23	0.013
sperm individualization	GO:0007291	48	0.013
establishment of blood nerve barrier	GO:0008065	2	0.013
regulation of transport	GO:0051049	181	0.013
cellular amino acid metabolic process	GO:0006520	61	0.013
tissue death	GO:0016271	102	0.013
border follicle cell migration	GO:0007298	113	0.013
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.013
mitotic nuclear division	GO:0007067	213	0.013
multi multicellular organism process	GO:0044706	123	0.013
immune response	GO:0006955	246	0.013
substrate adhesion dependent cell spreading	GO:0034446	2	0.013
purine containing compound metabolic process	GO:0072521	155	0.013
cell junction organization	GO:0034330	57	0.013
organelle fusion	GO:0048284	46	0.012
negative regulation of purine nucleotide biosynthetic process	GO:1900372	3	0.012
ovarian follicle cell development	GO:0030707	248	0.012
oocyte development	GO:0048599	124	0.012
response to oxygen containing compound	GO:1901700	200	0.012
neurological system process	GO:0050877	358	0.012
protein localization	GO:0008104	284	0.012
defense response to gram negative bacterium	GO:0050829	94	0.012
small molecule catabolic process	GO:0044282	21	0.012
gland development	GO:0048732	191	0.012
spindle organization	GO:0007051	253	0.012
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
organelle localization	GO:0051640	148	0.012
autophagic cell death	GO:0048102	83	0.012
developmental programmed cell death	GO:0010623	138	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
regulation of immune system process	GO:0002682	176	0.012
determination of adult lifespan	GO:0008340	137	0.012
cellular response to molecule of bacterial origin	GO:0071219	3	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
immune response activating signal transduction	GO:0002757	2	0.011
cellular response to chemical stimulus	GO:0070887	199	0.011
apoptotic process	GO:0006915	159	0.011
regulation of developmental growth	GO:0048638	174	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
response to nutrient levels	GO:0031667	114	0.011
interspecies interaction between organisms	GO:0044419	16	0.011
positive regulation of cell migration	GO:0030335	2	0.011
detection of external biotic stimulus	GO:0098581	2	0.011
regulation of defense response	GO:0031347	102	0.011
positive regulation of macromolecule metabolic process	GO:0010604	405	0.011
choline metabolic process	GO:0019695	1	0.011
positive regulation of gene expression	GO:0010628	290	0.011
cellular biogenic amine catabolic process	GO:0042402	1	0.011
phenol containing compound metabolic process	GO:0018958	57	0.011
heterocycle catabolic process	GO:0046700	166	0.011
embryo development ending in birth or egg hatching	GO:0009792	152	0.011
regulation of cell cycle process	GO:0010564	181	0.011
oocyte construction	GO:0007308	112	0.011
negative regulation of gene expression	GO:0010629	387	0.011
meiotic cell cycle process	GO:1903046	132	0.010
rhodopsin metabolic process	GO:0046154	10	0.010
negative regulation of protein metabolic process	GO:0051248	85	0.010
eye pigment metabolic process	GO:0042441	33	0.010
spindle assembly	GO:0051225	80	0.010
response to nitrogen compound	GO:1901698	90	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
pattern recognition receptor signaling pathway	GO:0002221	2	0.010
response to bacterium	GO:0009617	198	0.010
cellular homeostasis	GO:0019725	80	0.010
toll signaling pathway	GO:0008063	25	0.010
nucleoside metabolic process	GO:0009116	127	0.010
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010
protein phosphorylation	GO:0006468	169	0.010

CG4335 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.038
nervous system disease	DOID:863	0.023
cardiovascular system disease	DOID:1287	0.021
artery disease	DOID:0050828	0.021
hypertension	DOID:10763	0.021
vascular disease	DOID:178	0.021
essential hypertension	DOID:10825	0.016
neurodegenerative disease	DOID:1289	0.015
central nervous system disease	DOID:331	0.015

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