IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG14850 (Dmel_CG14850)

CG14850 gene product from transcript CG14850-RA

(Aliases: Dmel\CG14850)

Entrez: 41762
FLYBASE: FBgn0038239
UniProtKB: Q9VFI7

Process Predictions
Disease Predictions

CG14850 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
post embryonic appendage morphogenesis	GO:0035120	385	0.081
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.075
negative regulation of transcription dna templated	GO:0045892	237	0.070
wing disc morphogenesis	GO:0007472	344	0.068
salivary gland development	GO:0007431	162	0.067
appendage development	GO:0048736	401	0.064
appendage morphogenesis	GO:0035107	397	0.058
organonitrogen compound metabolic process	GO:1901564	318	0.052
imaginal disc derived appendage development	GO:0048737	399	0.048
regionalization	GO:0003002	416	0.046
negative regulation of gene expression	GO:0010629	387	0.045
gland development	GO:0048732	191	0.043
eggshell formation	GO:0030703	105	0.043
negative regulation of cellular metabolic process	GO:0031324	382	0.043
exocrine system development	GO:0035272	162	0.041
multi organism behavior	GO:0051705	175	0.041
positive regulation of macromolecule metabolic process	GO:0010604	405	0.040
compound eye development	GO:0048749	307	0.039
negative regulation of biosynthetic process	GO:0009890	277	0.038
catabolic process	GO:0009056	409	0.037
ovarian follicle cell development	GO:0030707	248	0.037
imaginal disc derived wing morphogenesis	GO:0007476	337	0.036
protein modification process	GO:0036211	438	0.036
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.036
response to lipopolysaccharide	GO:0032496	4	0.035
epithelial cell development	GO:0002064	274	0.035
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.034
response to bacterium	GO:0009617	198	0.034
eye development	GO:0001654	323	0.033
epithelial cell differentiation	GO:0030855	322	0.033
small molecule metabolic process	GO:0044281	305	0.033
cellular protein modification process	GO:0006464	438	0.033
immune system process	GO:0002376	347	0.033
transmembrane transport	GO:0055085	139	0.032
regulation of multicellular organismal development	GO:2000026	414	0.032
organic substance catabolic process	GO:1901575	308	0.032
positive regulation of biosynthetic process	GO:0009891	316	0.032
negative regulation of rna metabolic process	GO:0051253	251	0.032
connective tissue development	GO:0061448	3	0.032
chorion containing eggshell formation	GO:0007304	105	0.031
camera type eye development	GO:0043010	4	0.030
axon guidance	GO:0007411	233	0.030
regulation of cell differentiation	GO:0045595	302	0.029
body morphogenesis	GO:0010171	2	0.029
positive regulation of gene expression	GO:0010628	290	0.029
cellular catabolic process	GO:0044248	372	0.029
compound eye morphogenesis	GO:0001745	249	0.029
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.028
protein localization	GO:0008104	284	0.028
peptide metabolic process	GO:0006518	80	0.028
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.027
gene silencing	GO:0016458	138	0.027
positive regulation of cellular biosynthetic process	GO:0031328	316	0.027
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.026
cellular amino acid metabolic process	GO:0006520	61	0.026
regulation of cellular protein metabolic process	GO:0032268	243	0.026
cellular component assembly involved in morphogenesis	GO:0010927	151	0.026
response to other organism	GO:0051707	293	0.026
axon development	GO:0061564	297	0.025
vesicle mediated transport	GO:0016192	381	0.025
developmental growth	GO:0048589	280	0.025
developmental programmed cell death	GO:0010623	138	0.025
neuron projection guidance	GO:0097485	241	0.025
columnar cuboidal epithelial cell development	GO:0002066	249	0.025
phosphorylation	GO:0016310	294	0.025
sensory organ morphogenesis	GO:0090596	260	0.025
salivary gland morphogenesis	GO:0007435	145	0.024
taxis	GO:0042330	304	0.024
cuticle development	GO:0042335	86	0.023
neurological system process	GO:0050877	358	0.023
immune response	GO:0006955	246	0.023
multicellular organismal reproductive behavior	GO:0033057	110	0.023
phagocytosis	GO:0006909	215	0.023
sterol homeostasis	GO:0055092	4	0.023
protein phosphorylation	GO:0006468	169	0.023
forebrain development	GO:0030900	2	0.023
response to external biotic stimulus	GO:0043207	293	0.023
intracellular signal transduction	GO:0035556	300	0.023
establishment of localization in cell	GO:0051649	402	0.022
regulation of catalytic activity	GO:0050790	185	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.022
regulation of phosphorus metabolic process	GO:0051174	210	0.022
single organism catabolic process	GO:0044712	228	0.022
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021
telencephalon development	GO:0021537	2	0.021
response to alcohol	GO:0097305	95	0.021
transcription from rna polymerase ii promoter	GO:0006366	368	0.021
positive regulation of transcription dna templated	GO:0045893	266	0.021
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.021
ribose phosphate metabolic process	GO:0019693	145	0.021
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.021
regulation of neurogenesis	GO:0050767	158	0.021
single organism behavior	GO:0044708	391	0.021
purine containing compound metabolic process	GO:0072521	155	0.021
defense response to bacterium	GO:0042742	178	0.021
carbohydrate derivative metabolic process	GO:1901135	217	0.020
wound healing	GO:0042060	75	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.020
innate immune response	GO:0045087	144	0.020
kidney development	GO:0001822	3	0.020
positive regulation of signaling	GO:0023056	243	0.020
positive regulation of rna biosynthetic process	GO:1902680	266	0.020
open tracheal system development	GO:0007424	204	0.020
response to oxygen containing compound	GO:1901700	200	0.020
endocytosis	GO:0006897	310	0.020
purine nucleotide metabolic process	GO:0006163	146	0.020
autophagy	GO:0006914	108	0.020
cellular ketone metabolic process	GO:0042180	24	0.020
mating	GO:0007618	120	0.020
dorsal ventral pattern formation	GO:0009953	133	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
adult behavior	GO:0030534	137	0.020
segmentation	GO:0035282	207	0.019
positive regulation of response to stimulus	GO:0048584	323	0.019
organonitrogen compound catabolic process	GO:1901565	128	0.019
gland morphogenesis	GO:0022612	145	0.019
small gtpase mediated signal transduction	GO:0007264	88	0.019
positive regulation of rna metabolic process	GO:0051254	271	0.019
hindbrain development	GO:0030902	2	0.019
positive regulation of catalytic activity	GO:0043085	118	0.019
regulation of localization	GO:0032879	275	0.019
response to biotic stimulus	GO:0009607	294	0.019
eggshell chorion assembly	GO:0007306	66	0.018
hormone catabolic process	GO:0042447	3	0.018
purine ribonucleoside catabolic process	GO:0046130	112	0.018
carbohydrate derivative catabolic process	GO:1901136	118	0.018
retina development in camera type eye	GO:0060041	4	0.018
locomotory behavior	GO:0007626	176	0.018
cellular macromolecule localization	GO:0070727	220	0.018
amine metabolic process	GO:0009308	12	0.018
purine ribonucleotide metabolic process	GO:0009150	145	0.018
synaptic transmission	GO:0007268	288	0.018
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.018
regulation of cellular amino acid metabolic process	GO:0006521	0	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
negative regulation of response to stimulus	GO:0048585	258	0.018
cellular amide metabolic process	GO:0043603	80	0.017
nucleoside phosphate metabolic process	GO:0006753	162	0.017
nucleotide metabolic process	GO:0009117	161	0.017
central nervous system development	GO:0007417	201	0.017
death	GO:0016265	284	0.017
single organism biosynthetic process	GO:0044711	206	0.017
response to organic substance	GO:0010033	284	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.017
respiratory system development	GO:0060541	213	0.017
actin cytoskeleton organization	GO:0030036	206	0.017
inter male aggressive behavior	GO:0002121	60	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
water homeostasis	GO:0030104	3	0.017
regulation of anatomical structure size	GO:0090066	163	0.017
histolysis	GO:0007559	102	0.017
dendrite morphogenesis	GO:0048813	199	0.017
positive regulation of molecular function	GO:0044093	136	0.017
cellular amine metabolic process	GO:0044106	12	0.017
organophosphate metabolic process	GO:0019637	195	0.017
positive regulation of phosphorus metabolic process	GO:0010562	139	0.017
carboxylic acid metabolic process	GO:0019752	92	0.017
cellular protein localization	GO:0034613	160	0.017
regulation of phosphate metabolic process	GO:0019220	210	0.016
aromatic compound catabolic process	GO:0019439	166	0.016
nucleobase containing compound catabolic process	GO:0034655	165	0.016
negative regulation of developmental process	GO:0051093	201	0.016
salt aversion	GO:0035199	3	0.016
anion homeostasis	GO:0055081	3	0.016
positive regulation of phosphorylation	GO:0042327	87	0.016
drinking behavior	GO:0042756	2	0.016
regulation of molecular function	GO:0065009	217	0.016
morphogenesis of an epithelium	GO:0002009	276	0.016
cell division	GO:0051301	248	0.016
cell motility	GO:0048870	251	0.016
cell death	GO:0008219	279	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
morphogenesis of a polarized epithelium	GO:0001738	93	0.016
anterior posterior pattern specification	GO:0009952	136	0.016
positive regulation of phosphate metabolic process	GO:0045937	139	0.016
organic acid metabolic process	GO:0006082	103	0.016
regulation of gene expression epigenetic	GO:0040029	128	0.016
synapse assembly	GO:0007416	143	0.016
response to abiotic stimulus	GO:0009628	341	0.016
response to temperature stimulus	GO:0009266	106	0.015
regulation of gene silencing	GO:0060968	63	0.015
oxoacid metabolic process	GO:0043436	103	0.015
positive regulation of cell migration	GO:0030335	2	0.015
programmed cell death	GO:0012501	257	0.015
homeostatic process	GO:0042592	199	0.015
benzene containing compound metabolic process	GO:0042537	3	0.015
chemotaxis	GO:0006935	249	0.015
response to ethanol	GO:0045471	59	0.015
defense response to other organism	GO:0098542	225	0.015
posttranscriptional regulation of gene expression	GO:0010608	145	0.015
response to extracellular stimulus	GO:0009991	116	0.015
positive regulation of lipid storage	GO:0010884	4	0.015
blastoderm segmentation	GO:0007350	159	0.015
chaeta development	GO:0022416	97	0.015
positive regulation of cell communication	GO:0010647	250	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
regulation of synapse structure and activity	GO:0050803	128	0.015
eye photoreceptor cell differentiation	GO:0001754	145	0.015
reproductive behavior	GO:0019098	122	0.015
regulation of cell development	GO:0060284	215	0.015
defense response to gram negative bacterium	GO:0050829	94	0.015
single organism intracellular transport	GO:1902582	207	0.015
embryonic pattern specification	GO:0009880	174	0.015
cytoplasm organization	GO:0007028	64	0.015
androgen metabolic process	GO:0008209	1	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.015
molting cycle chitin based cuticle	GO:0007591	56	0.015
positive regulation of cell motility	GO:2000147	3	0.015
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.015
heterocycle catabolic process	GO:0046700	166	0.015
negative regulation of cell differentiation	GO:0045596	143	0.015
purine ribonucleoside metabolic process	GO:0046128	127	0.014
cellular nitrogen compound catabolic process	GO:0044270	165	0.014
g protein coupled receptor signaling pathway	GO:0007186	136	0.014
steroid catabolic process	GO:0006706	1	0.014
aggressive behavior	GO:0002118	63	0.014
proteolysis	GO:0006508	192	0.014
organonitrogen compound biosynthetic process	GO:1901566	117	0.014
photoreceptor cell development	GO:0042461	96	0.014
ras protein signal transduction	GO:0007265	88	0.014
regulation of transport	GO:0051049	181	0.014
learning or memory	GO:0007611	141	0.014
purine nucleoside metabolic process	GO:0042278	127	0.014
actin filament based process	GO:0030029	220	0.014
signal transduction by phosphorylation	GO:0023014	107	0.014
negative regulation of developmental growth	GO:0048640	64	0.014
ribonucleotide catabolic process	GO:0009261	109	0.014
organic substance transport	GO:0071702	257	0.014
negative regulation of gene expression epigenetic	GO:0045814	77	0.014
multi multicellular organism process	GO:0044706	123	0.014
vitamin biosynthetic process	GO:0009110	1	0.014
growth	GO:0040007	359	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.013
regulation of nervous system development	GO:0051960	248	0.013
nucleoside triphosphate metabolic process	GO:0009141	120	0.013
establishment of tissue polarity	GO:0007164	87	0.013
axonogenesis	GO:0007409	290	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013
camera type eye morphogenesis	GO:0048593	2	0.013
positive regulation of protein metabolic process	GO:0051247	128	0.013
cellular response to molecule of bacterial origin	GO:0071219	3	0.013
tissue morphogenesis	GO:0048729	297	0.013
negative regulation of rna biosynthetic process	GO:1902679	240	0.013
intracellular transport	GO:0046907	228	0.013
organophosphate catabolic process	GO:0046434	112	0.013
ribonucleoside catabolic process	GO:0042454	112	0.013
response to copper ion	GO:0046688	4	0.013
regulation of growth	GO:0040008	233	0.013
l amino acid import	GO:0043092	2	0.013
autophagic cell death	GO:0048102	83	0.013
chromatin silencing	GO:0006342	76	0.013
compound eye photoreceptor cell differentiation	GO:0001751	140	0.013
cuticle pattern formation	GO:0035017	27	0.013
dendrite development	GO:0016358	204	0.013
biological adhesion	GO:0022610	138	0.013
monocarboxylic acid transport	GO:0015718	3	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.013
nucleoside metabolic process	GO:0009116	127	0.013
peptidyl amino acid modification	GO:0018193	105	0.013
oocyte construction	GO:0007308	112	0.013
phenol containing compound metabolic process	GO:0018958	57	0.013
localization of cell	GO:0051674	257	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.013
limb development	GO:0060173	1	0.013
dorsal appendage formation	GO:0046843	47	0.013
mitotic spindle organization	GO:0007052	220	0.012
response to organic cyclic compound	GO:0014070	89	0.012
regulation of lipid transport	GO:0032368	3	0.012
maintenance of location	GO:0051235	73	0.012
sensory perception of chemical stimulus	GO:0007606	116	0.012
response to pain	GO:0048265	3	0.012
acid secretion	GO:0046717	1	0.012
regulation of epithelial cell differentiation	GO:0030856	4	0.012
mesenchymal cell development	GO:0014031	1	0.012
salivary gland cell autophagic cell death	GO:0035071	83	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
regulation of cell cycle process	GO:0010564	181	0.012
learning	GO:0007612	75	0.012
embryonic axis specification	GO:0000578	107	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
regulation of behavior	GO:0050795	75	0.012
nucleoside phosphate catabolic process	GO:1901292	110	0.012
non sensory hair organization	GO:0035316	47	0.012
nucleoside catabolic process	GO:0009164	112	0.012
negative regulation of growth	GO:0045926	84	0.012
cell proliferation	GO:0008283	299	0.012
cellular response to organic substance	GO:0071310	132	0.012
photoreceptor cell differentiation	GO:0046530	170	0.012
feeding behavior	GO:0007631	50	0.012
humoral immune response	GO:0006959	117	0.012
neuron recognition	GO:0008038	101	0.012
purine containing compound catabolic process	GO:0072523	112	0.012
macromolecular complex assembly	GO:0065003	256	0.012
response to alkaloid	GO:0043279	26	0.012
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.012
anterior posterior axis specification embryo	GO:0008595	103	0.012
regulation of immune system process	GO:0002682	176	0.012
single organism cellular localization	GO:1902580	180	0.012
cognition	GO:0050890	141	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.012
defense response	GO:0006952	300	0.012
multi organism reproductive behavior	GO:0044705	121	0.012
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.012
immune effector process	GO:0002252	98	0.012
apoptotic process	GO:0006915	159	0.012
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.012
wnt signaling pathway	GO:0016055	98	0.011
wound healing spreading of epidermal cells	GO:0035313	1	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
purine ribonucleotide catabolic process	GO:0009154	109	0.011
regulation of mapk cascade	GO:0043408	92	0.011
negative regulation of cell communication	GO:0010648	223	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
tripartite regional subdivision	GO:0007351	103	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
fat soluble vitamin biosynthetic process	GO:0042362	1	0.011
response to wounding	GO:0009611	94	0.011
mapk cascade	GO:0000165	107	0.011
extrinsic apoptotic signaling pathway	GO:0097191	1	0.011
instar larval development	GO:0002168	55	0.011
regulation of embryonic development	GO:0045995	68	0.011
salivary gland histolysis	GO:0035070	88	0.011
glycerolipid catabolic process	GO:0046503	3	0.011
somatic muscle development	GO:0007525	66	0.011
positive regulation of cellular amine metabolic process	GO:0033240	0	0.011
anterior posterior axis specification	GO:0009948	109	0.011
regulation of cellular component biogenesis	GO:0044087	201	0.011
inorganic cation transmembrane transport	GO:0098662	61	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.011
organelle assembly	GO:0070925	198	0.011
fat soluble vitamin metabolic process	GO:0006775	1	0.011
cell recognition	GO:0008037	102	0.011
regulation of anatomical structure morphogenesis	GO:0022603	242	0.011
epiboly involved in wound healing	GO:0090505	2	0.011
xenobiotic catabolic process	GO:0042178	1	0.011
ion transport	GO:0006811	145	0.011
sensory perception of pain	GO:0019233	4	0.011
axis specification	GO:0009798	167	0.011
head development	GO:0060322	135	0.011
neutral lipid biosynthetic process	GO:0046460	2	0.011
positive regulation of cellular component biogenesis	GO:0044089	80	0.011
gene silencing by rna	GO:0031047	57	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
cellular response to ethanol	GO:0071361	4	0.011
spinal cord development	GO:0021510	1	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
activation of innate immune response	GO:0002218	4	0.011
immune response activating signal transduction	GO:0002757	2	0.011
brain development	GO:0007420	120	0.011
ribonucleoside metabolic process	GO:0009119	127	0.011
ion transmembrane transport	GO:0034220	122	0.011
regulation of nucleotide metabolic process	GO:0006140	62	0.011
triglyceride catabolic process	GO:0019433	3	0.011
phosphatidic acid metabolic process	GO:0046473	1	0.011
intracellular protein transmembrane transport	GO:0065002	4	0.011
regulation of nucleoside metabolic process	GO:0009118	50	0.011
regulation of epithelial cell proliferation	GO:0050678	4	0.011
rna localization	GO:0006403	115	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
acylglycerol catabolic process	GO:0046464	3	0.011
polyol biosynthetic process	GO:0046173	3	0.011
regulation of cell substrate adhesion	GO:0010810	2	0.011
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.011
epiboly	GO:0090504	2	0.011
memory	GO:0007613	94	0.011
regulation of hydrolase activity	GO:0051336	97	0.011
regulation of protein phosphorylation	GO:0001932	64	0.011
translation	GO:0006412	69	0.011
response to monosaccharide	GO:0034284	4	0.011
oocyte axis specification	GO:0007309	108	0.011
innate immune response activating signal transduction	GO:0002758	2	0.010
regulation of cell cycle	GO:0051726	291	0.010
developmental maturation	GO:0021700	172	0.010
oocyte differentiation	GO:0009994	145	0.010
intracellular protein transport	GO:0006886	104	0.010
cellular response to lipopolysaccharide	GO:0071222	3	0.010
kidney epithelium development	GO:0072073	3	0.010
olfactory learning	GO:0008355	56	0.010
muscle organ development	GO:0007517	127	0.010
pole plasm assembly	GO:0007315	61	0.010
regulation of phosphorylation	GO:0042325	147	0.010
tissue death	GO:0016271	102	0.010
phospholipid homeostasis	GO:0055091	1	0.010
regulation of sequestering of triglyceride	GO:0010889	3	0.010
regulation of organelle organization	GO:0033043	196	0.010
neural retina development	GO:0003407	4	0.010
neuromuscular synaptic transmission	GO:0007274	67	0.010
nuclear division	GO:0000280	332	0.010
endomembrane system organization	GO:0010256	119	0.010
carbohydrate derivative biosynthetic process	GO:1901137	85	0.010
response to nitrogen compound	GO:1901698	90	0.010
positive regulation of cell differentiation	GO:0045597	64	0.010
limb morphogenesis	GO:0035108	1	0.010

CG14850 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.031
disease of metabolism	DOID:0014667	0.031
hypophosphatasia	DOID:14213	0.030
cardiovascular system disease	DOID:1287	0.024
nervous system disease	DOID:863	0.021
inherited metabolic disorder	DOID:655	0.018
acquired metabolic disease	DOID:0060158	0.016
urinary system disease	DOID:18	0.013
renal tubular transport disease	DOID:447	0.013
kidney disease	DOID:557	0.013
musculoskeletal system disease	DOID:17	0.013
vascular disease	DOID:178	0.012
sensory system disease	DOID:0050155	0.012
hypertension	DOID:10763	0.011
artery disease	DOID:0050828	0.011
glucose metabolism disease	DOID:4194	0.011
carbohydrate metabolism disease	DOID:0050013	0.011
diabetes mellitus	DOID:9351	0.011
essential hypertension	DOID:10825	0.010
type 2 diabetes mellitus	DOID:9352	0.010

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