Drosophila melanogaster

56 known processes

Rpn11 (Dmel_CG18174)

CG18174 gene product from transcript CG18174-RA

(Aliases: Dmel\CG18174,RPn11,CG18174,37B,S13,yip5,DmS13,RPN11,p37B)

Rpn11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent macromolecule catabolic processGO:0043632790.915
cellular catabolic processGO:00442483720.740
catabolic processGO:00090564090.699
cellular macromolecule catabolic processGO:00442651360.640
protein dna complex assemblyGO:0065004630.602
proteasome assemblyGO:004324820.587
cellular response to dna damage stimulusGO:00069742230.529
Human
cellular protein catabolic processGO:0044257830.490
organic substance catabolic processGO:19015753080.481
macromolecule catabolic processGO:00090571610.471
proteolysisGO:00065081920.464
mitotic spindle organizationGO:00070522200.434
protein ubiquitinationGO:0016567700.409
protein modification by small protein conjugation or removalGO:00706471060.408
Human Yeast
modification dependent protein catabolic processGO:0019941780.398
positive regulation of nitrogen compound metabolic processGO:00511733540.364
dna templated transcriptional preinitiation complex assemblyGO:0070897200.336
proteasomal protein catabolic processGO:0010498590.330
regulation of peptidase activityGO:0052547390.299
Human
agingGO:00075681430.268
Worm
positive regulation of gene expressionGO:00106282900.268
rna polymerase ii transcriptional preinitiation complex assemblyGO:0051123200.266
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.256
regulation of cellular protein metabolic processGO:00322682430.255
determination of adult lifespanGO:00083401370.253
Worm
proteolysis involved in cellular protein catabolic processGO:0051603830.239
regulation of molecular functionGO:00650092170.225
Human
multicellular organismal agingGO:00102591400.210
Worm
protein modification by small protein conjugationGO:0032446790.199
transcription initiation from rna polymerase ii promoterGO:0006367250.197
cell proliferationGO:00082832990.196
spindle organizationGO:00070512530.178
larval developmentGO:00021641040.178
Worm
protein complex assemblyGO:00064612000.171
cullin deneddylationGO:001038830.167
ubiquitin dependent protein catabolic processGO:0006511780.162
protein modification processGO:00362114380.161
Human Yeast
organelle fissionGO:00482853400.160
Yeast
protein deneddylationGO:000033880.155
protein modification by small protein removalGO:0070646280.152
Human Yeast
dna templated transcription initiationGO:0006352250.151
regulation of protein metabolic processGO:00512462560.145
protein complex biogenesisGO:00702712010.131
positive regulation of macromolecule metabolic processGO:00106044050.126
cellular macromolecular complex assemblyGO:00346221530.116
positive regulation of transcription dna templatedGO:00458932660.107
positive regulation of rna metabolic processGO:00512542710.107
negative regulation of cellular metabolic processGO:00313243820.105
aromatic compound catabolic processGO:00194391660.101
positive regulation of nucleobase containing compound metabolic processGO:00459353320.100
posttranscriptional gene silencing by rnaGO:0035194450.097
protein catabolic processGO:00301631010.095
nucleobase containing compound catabolic processGO:00346551650.094
embryo development ending in birth or egg hatchingGO:00097921520.093
Worm
cellular nitrogen compound catabolic processGO:00442701650.088
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589810.086
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.086
regulation of mitotic cell cycleGO:00073461900.085
organic cyclic compound catabolic processGO:19013611680.083
cellular protein complex assemblyGO:0043623710.083
positive regulation of cellular component organizationGO:00511301560.083
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.082
regulation of gene expression epigeneticGO:00400291280.081
rna catabolic processGO:0006401370.079
positive regulation of peptidase activityGO:0010952290.078
Human
cellular protein modification processGO:00064644380.078
Human Yeast
regulation of catabolic processGO:00098941700.078
negative regulation of gene expressionGO:00106293870.074
developmental growthGO:00485892800.074
regionalizationGO:00030024160.073
positive regulation of cellular biosynthetic processGO:00313283160.072
regulation of proteasomal protein catabolic processGO:0061136390.072
nuclear divisionGO:00002803320.072
positive regulation of nucleic acid templated transcriptionGO:19035082660.071
gene silencing by rnaGO:0031047570.069
microtubule organizing center organizationGO:00310231680.067
dna metabolic processGO:00062592270.067
Human
regulation of endopeptidase activityGO:0052548360.066
Human
heterocycle catabolic processGO:00467001660.065
positive regulation of cellular component biogenesisGO:0044089800.065
organonitrogen compound metabolic processGO:19015643180.064
regulation of transcription from rna polymerase ii promoterGO:00063573780.061
regulation of cell cycleGO:00517262910.059
purine nucleoside catabolic processGO:00061521120.058
positive regulation of proteasomal protein catabolic processGO:1901800200.057
regulation of catalytic activityGO:00507901850.057
Human
negative regulation of nitrogen compound metabolic processGO:00511722650.056
spindle elongationGO:0051231830.056
centrosome organizationGO:00512971630.055
purine ribonucleoside triphosphate catabolic processGO:00092071080.055
negative regulation of signalingGO:00230572190.054
intracellular transportGO:00469072280.053
positive regulation of rna biosynthetic processGO:19026802660.053
positive regulation of protein complex assemblyGO:0031334220.052
regulation of response to external stimulusGO:00321011150.049
apoptotic processGO:00069151590.048
macromolecular complex assemblyGO:00650032560.047
posttranscriptional gene silencingGO:0016441460.046
carbohydrate derivative metabolic processGO:19011352170.045
cell maturationGO:00484691440.045
glycosyl compound catabolic processGO:19016581120.043
body morphogenesisGO:001017120.042
mitotic spindle elongationGO:0000022810.042
regulation of protein modification processGO:00313991120.041
er associated ubiquitin dependent protein catabolic processGO:003043330.041
posttranscriptional regulation of gene expressionGO:00106081450.040
dorsal ventral pattern formationGO:00099531330.040
ribose phosphate metabolic processGO:00196931450.040
protein deubiquitinationGO:0016579170.040
Human Yeast
deathGO:00162652840.039
positive regulation of cellular catabolic processGO:0031331950.039
negative regulation of signal transductionGO:00099682060.038
reproductive system developmentGO:0061458740.038
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.038
positive regulation of proteolysisGO:0045862520.037
regulation of hydrolase activityGO:0051336970.037
Human
transcription from rna polymerase ii promoterGO:00063663680.037
cell deathGO:00082192790.035
programmed cell deathGO:00125012570.034
organonitrogen compound catabolic processGO:19015651280.032
ribonucleoside triphosphate catabolic processGO:00092031080.032
negative regulation of cellular protein metabolic processGO:0032269850.032
mitotic nuclear divisionGO:00070672130.032
regulation of multicellular organismal developmentGO:20000264140.032
gene silencingGO:00164581380.030
negative regulation of response to stimulusGO:00485852580.030
purine ribonucleotide catabolic processGO:00091541090.030
developmental maturationGO:00217001720.030
organophosphate catabolic processGO:00464341120.030
dna repairGO:0006281540.030
Human
regulation of cellular protein catabolic processGO:1903362440.029
organelle assemblyGO:00709251980.028
negative regulation of cellular biosynthetic processGO:00313272770.028
regulation of vesicle mediated transportGO:0060627590.028
negative regulation of cell communicationGO:00106482230.027
nucleotide excision repairGO:000628980.027
nucleoside triphosphate catabolic processGO:00091431080.027
regulation of cellular component biogenesisGO:00440872010.026
nucleobase containing small molecule metabolic processGO:00550861740.026
nucleoside phosphate metabolic processGO:00067531620.026
dna templated transcription elongationGO:0006354180.026
purine nucleoside triphosphate catabolic processGO:00091461080.025
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.025
cell cell signaling involved in cell fate commitmentGO:00451682100.024
microtubule cytoskeleton organization involved in mitosisGO:1902850520.024
endocytosisGO:00068973100.024
spinal cord developmentGO:002151010.024
nucleotide catabolic processGO:00091661090.024
negative regulation of protein metabolic processGO:0051248850.024
regulation of mitosisGO:0007088560.024
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.023
purine containing compound catabolic processGO:00725231120.023
positive regulation of protein metabolic processGO:00512471280.023
rna interferenceGO:0016246270.023
chromosome segregationGO:00070591570.023
protein dna complex subunit organizationGO:0071824860.023
epithelial cell differentiationGO:00308553220.022
response to abiotic stimulusGO:00096283410.022
regulation of intracellular protein transportGO:0033157460.022
regulation of proteolysisGO:0030162870.022
spindle assembly involved in mitosisGO:0090307500.021
negative regulation of biosynthetic processGO:00098902770.021
positive regulation of biosynthetic processGO:00098913160.021
single organism biosynthetic processGO:00447112060.021
positive regulation of developmental processGO:00510941430.021
purine containing compound metabolic processGO:00725211550.021
response to external biotic stimulusGO:00432072930.021
positive regulation of hydrolase activityGO:0051345780.021
Human
nucleoside phosphate catabolic processGO:19012921100.021
ribonucleoside metabolic processGO:00091191270.021
glycosyl compound metabolic processGO:19016571270.021
regulation of cellular catabolic processGO:00313291570.020
growthGO:00400073590.020
lateral inhibitionGO:00463312060.020
regulation of protein modification by small protein conjugation or removalGO:1903320250.020
gland morphogenesisGO:00226121450.019
phagocytosisGO:00069092150.019
regulation of protein ubiquitinationGO:0031396220.019
regulation of cell divisionGO:0051302720.019
ribonucleoside catabolic processGO:00424541120.019
purine ribonucleoside catabolic processGO:00461301120.019
negative regulation of molecular functionGO:0044092510.019
ribonucleotide metabolic processGO:00092591450.019
regulation of developmental growthGO:00486381740.019
positive regulation of macromolecule biosynthetic processGO:00105572830.018
smoothened signaling pathwayGO:0007224490.018
regulation of organelle organizationGO:00330431960.018
regulation of multi organism processGO:00439001310.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.017
ribonucleotide catabolic processGO:00092611090.017
nucleoside catabolic processGO:00091641120.017
positive regulation of response to stimulusGO:00485843230.017
regulation of wnt signaling pathwayGO:0030111680.017
spindle assemblyGO:0051225800.017
purine ribonucleotide metabolic processGO:00091501450.017
positive regulation of growthGO:0045927750.017
chromosome separationGO:0051304420.017
positive regulation of cellular protein metabolic processGO:00322701180.016
single organism catabolic processGO:00447122280.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
nucleotide metabolic processGO:00091171610.016
positive regulation of transportGO:0051050920.016
negative regulation of proteasomal protein catabolic processGO:1901799160.016
regulation of cell cycle processGO:00105641810.016
purine nucleotide metabolic processGO:00061631460.016
positive regulation of catalytic activityGO:00430851180.016
Human
purine nucleotide catabolic processGO:00061951090.016
protein maturationGO:0051604710.015
sex differentiationGO:0007548810.015
maintenance of location in cellGO:0051651280.015
entry into cell of other organism involved in symbiotic interactionGO:005180630.015
response to organic substanceGO:00100332840.015
positive regulation of cell communicationGO:00106472500.015
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
regulation of protein processingGO:0070613320.015
positive regulation of catabolic processGO:00098961050.014
positive regulation of signal transductionGO:00099672230.014
organophosphate metabolic processGO:00196371950.014
purine ribonucleoside metabolic processGO:00461281270.014
regulation of intracellular transportGO:0032386640.014
photoreceptor cell differentiationGO:00465301700.013
regulation of smoothened signaling pathwayGO:0008589280.013
negative regulation of proteolysisGO:0045861310.013
response to endogenous stimulusGO:00097191190.013
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.013
taxisGO:00423303040.013
response to heatGO:0009408630.013
regulation of intracellular signal transductionGO:19025312360.013
nucleoside triphosphate metabolic processGO:00091411200.012
mitotic dna damage checkpointGO:0044773740.012
chromatin modificationGO:00165681470.012
regulation of cellular ketone metabolic processGO:001056530.012
anterior posterior axis specification embryoGO:00085951030.012
morphogenesis of an epitheliumGO:00020092760.012
positive regulation of multicellular organismal processGO:00512401430.012
regulation of protein complex assemblyGO:0043254420.012
tube developmentGO:00352952440.011
membrane organizationGO:00610241120.011
carbohydrate derivative catabolic processGO:19011361180.011
response to nutrient levelsGO:00316671140.011
dna integrity checkpointGO:0031570810.011
mitotic g2 dna damage checkpointGO:0007095690.011
anterior posterior pattern specificationGO:00099521360.011
imaginal disc derived wing morphogenesisGO:00074763370.011
mrna catabolic processGO:0006402330.011
regulation of apoptotic processGO:00429811300.011
response to other organismGO:00517072930.011
mrna cis splicing via spliceosomeGO:004529210.011
nucleoside metabolic processGO:00091161270.011
dendrite developmentGO:00163582040.011
positive regulation of signalingGO:00230562430.011
response to radiationGO:00093141550.010
regulation of ras protein signal transductionGO:0046578930.010
enzyme linked receptor protein signaling pathwayGO:00071671790.010
regulation of localizationGO:00328792750.010
regulation of notch signaling pathwayGO:00085931000.010
embryonic morphogenesisGO:00485982060.010
segmentationGO:00352822070.010
purine nucleoside monophosphate catabolic processGO:0009128380.010
nuclear transcribed mrna catabolic processGO:0000956240.010
response to organic cyclic compoundGO:0014070890.010

Rpn11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.057
nervous system diseaseDOID:86300.027