| modification dependent macromolecule catabolic process | GO:0043632 | 79 | 0.915 | |
| cellular catabolic process | GO:0044248 | 372 | 0.740 | |
| catabolic process | GO:0009056 | 409 | 0.699 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.640 | |
| protein dna complex assembly | GO:0065004 | 63 | 0.602 | |
| proteasome assembly | GO:0043248 | 2 | 0.587 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.529 | Human |
| cellular protein catabolic process | GO:0044257 | 83 | 0.490 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.481 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.471 | |
| proteolysis | GO:0006508 | 192 | 0.464 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.434 | |
| protein ubiquitination | GO:0016567 | 70 | 0.409 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 106 | 0.408 | Human Yeast |
| modification dependent protein catabolic process | GO:0019941 | 78 | 0.398 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.364 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 20 | 0.336 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.330 | |
| regulation of peptidase activity | GO:0052547 | 39 | 0.299 | Human |
| aging | GO:0007568 | 143 | 0.268 | Worm |
| positive regulation of gene expression | GO:0010628 | 290 | 0.268 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 20 | 0.266 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 54 | 0.256 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.255 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.253 | Worm |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 83 | 0.239 | |
| regulation of molecular function | GO:0065009 | 217 | 0.225 | Human |
| multicellular organismal aging | GO:0010259 | 140 | 0.210 | Worm |
| protein modification by small protein conjugation | GO:0032446 | 79 | 0.199 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 25 | 0.197 | |
| cell proliferation | GO:0008283 | 299 | 0.196 | |
| spindle organization | GO:0007051 | 253 | 0.178 | |
| larval development | GO:0002164 | 104 | 0.178 | Worm |
| protein complex assembly | GO:0006461 | 200 | 0.171 | |
| cullin deneddylation | GO:0010388 | 3 | 0.167 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.162 | |
| protein modification process | GO:0036211 | 438 | 0.161 | Human Yeast |
| organelle fission | GO:0048285 | 340 | 0.160 | Yeast |
| protein deneddylation | GO:0000338 | 8 | 0.155 | |
| protein modification by small protein removal | GO:0070646 | 28 | 0.152 | Human Yeast |
| dna templated transcription initiation | GO:0006352 | 25 | 0.151 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.145 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.131 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.126 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.116 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.107 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.107 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.105 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.101 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.100 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 45 | 0.097 | |
| protein catabolic process | GO:0030163 | 101 | 0.095 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.094 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.093 | Worm |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.088 | |
| regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045898 | 1 | 0.086 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 44 | 0.086 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.085 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.083 | |
| cellular protein complex assembly | GO:0043623 | 71 | 0.083 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.083 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.082 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.081 | |
| rna catabolic process | GO:0006401 | 37 | 0.079 | |
| positive regulation of peptidase activity | GO:0010952 | 29 | 0.078 | Human |
| cellular protein modification process | GO:0006464 | 438 | 0.078 | Human Yeast |
| regulation of catabolic process | GO:0009894 | 170 | 0.078 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.074 | |
| developmental growth | GO:0048589 | 280 | 0.074 | |
| regionalization | GO:0003002 | 416 | 0.073 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.072 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 39 | 0.072 | |
| nuclear division | GO:0000280 | 332 | 0.072 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.071 | |
| gene silencing by rna | GO:0031047 | 57 | 0.069 | |
| microtubule organizing center organization | GO:0031023 | 168 | 0.067 | |
| dna metabolic process | GO:0006259 | 227 | 0.067 | Human |
| regulation of endopeptidase activity | GO:0052548 | 36 | 0.066 | Human |
| heterocycle catabolic process | GO:0046700 | 166 | 0.065 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.065 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.064 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.061 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.059 | |
| purine nucleoside catabolic process | GO:0006152 | 112 | 0.058 | |
| positive regulation of proteasomal protein catabolic process | GO:1901800 | 20 | 0.057 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.057 | Human |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.056 | |
| spindle elongation | GO:0051231 | 83 | 0.056 | |
| centrosome organization | GO:0051297 | 163 | 0.055 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 108 | 0.055 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.054 | |
| intracellular transport | GO:0046907 | 228 | 0.053 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.053 | |
| positive regulation of protein complex assembly | GO:0031334 | 22 | 0.052 | |
| regulation of response to external stimulus | GO:0032101 | 115 | 0.049 | |
| apoptotic process | GO:0006915 | 159 | 0.048 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.047 | |
| posttranscriptional gene silencing | GO:0016441 | 46 | 0.046 | |
| carbohydrate derivative metabolic process | GO:1901135 | 217 | 0.045 | |
| cell maturation | GO:0048469 | 144 | 0.045 | |
| glycosyl compound catabolic process | GO:1901658 | 112 | 0.043 | |
| body morphogenesis | GO:0010171 | 2 | 0.042 | |
| mitotic spindle elongation | GO:0000022 | 81 | 0.042 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.041 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 3 | 0.041 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.040 | |
| dorsal ventral pattern formation | GO:0009953 | 133 | 0.040 | |
| ribose phosphate metabolic process | GO:0019693 | 145 | 0.040 | |
| protein deubiquitination | GO:0016579 | 17 | 0.040 | Human Yeast |
| death | GO:0016265 | 284 | 0.039 | |
| positive regulation of cellular catabolic process | GO:0031331 | 95 | 0.039 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.038 | |
| reproductive system development | GO:0061458 | 74 | 0.038 | |
| positive regulation of proteolysis involved in cellular protein catabolic process | GO:1903052 | 24 | 0.038 | |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.037 | |
| regulation of hydrolase activity | GO:0051336 | 97 | 0.037 | Human |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.037 | |
| cell death | GO:0008219 | 279 | 0.035 | |
| programmed cell death | GO:0012501 | 257 | 0.034 | |
| organonitrogen compound catabolic process | GO:1901565 | 128 | 0.032 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 108 | 0.032 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.032 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.032 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.032 | |
| gene silencing | GO:0016458 | 138 | 0.030 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.030 | |
| purine ribonucleotide catabolic process | GO:0009154 | 109 | 0.030 | |
| developmental maturation | GO:0021700 | 172 | 0.030 | |
| organophosphate catabolic process | GO:0046434 | 112 | 0.030 | |
| dna repair | GO:0006281 | 54 | 0.030 | Human |
| regulation of cellular protein catabolic process | GO:1903362 | 44 | 0.029 | |
| organelle assembly | GO:0070925 | 198 | 0.028 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.028 | |
| regulation of vesicle mediated transport | GO:0060627 | 59 | 0.028 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.027 | |
| nucleotide excision repair | GO:0006289 | 8 | 0.027 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 108 | 0.027 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.026 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 174 | 0.026 | |
| nucleoside phosphate metabolic process | GO:0006753 | 162 | 0.026 | |
| dna templated transcription elongation | GO:0006354 | 18 | 0.026 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 108 | 0.025 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 37 | 0.025 | |
| cell cell signaling involved in cell fate commitment | GO:0045168 | 210 | 0.024 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 52 | 0.024 | |
| endocytosis | GO:0006897 | 310 | 0.024 | |
| spinal cord development | GO:0021510 | 1 | 0.024 | |
| nucleotide catabolic process | GO:0009166 | 109 | 0.024 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.024 | |
| regulation of mitosis | GO:0007088 | 56 | 0.024 | |
| positive regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032436 | 19 | 0.023 | |
| purine containing compound catabolic process | GO:0072523 | 112 | 0.023 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.023 | |
| rna interference | GO:0016246 | 27 | 0.023 | |
| chromosome segregation | GO:0007059 | 157 | 0.023 | |
| protein dna complex subunit organization | GO:0071824 | 86 | 0.023 | |
| epithelial cell differentiation | GO:0030855 | 322 | 0.022 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.022 | |
| regulation of intracellular protein transport | GO:0033157 | 46 | 0.022 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.022 | |
| spindle assembly involved in mitosis | GO:0090307 | 50 | 0.021 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.021 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.021 | |
| single organism biosynthetic process | GO:0044711 | 206 | 0.021 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.021 | |
| purine containing compound metabolic process | GO:0072521 | 155 | 0.021 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.021 | |
| positive regulation of hydrolase activity | GO:0051345 | 78 | 0.021 | Human |
| nucleoside phosphate catabolic process | GO:1901292 | 110 | 0.021 | |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.021 | |
| glycosyl compound metabolic process | GO:1901657 | 127 | 0.021 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.020 | |
| growth | GO:0040007 | 359 | 0.020 | |
| lateral inhibition | GO:0046331 | 206 | 0.020 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 25 | 0.020 | |
| gland morphogenesis | GO:0022612 | 145 | 0.019 | |
| phagocytosis | GO:0006909 | 215 | 0.019 | |
| regulation of protein ubiquitination | GO:0031396 | 22 | 0.019 | |
| regulation of cell division | GO:0051302 | 72 | 0.019 | |
| ribonucleoside catabolic process | GO:0042454 | 112 | 0.019 | |
| purine ribonucleoside catabolic process | GO:0046130 | 112 | 0.019 | |
| negative regulation of molecular function | GO:0044092 | 51 | 0.019 | |
| ribonucleotide metabolic process | GO:0009259 | 145 | 0.019 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.019 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.018 | |
| smoothened signaling pathway | GO:0007224 | 49 | 0.018 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.018 | |
| regulation of multi organism process | GO:0043900 | 131 | 0.017 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 38 | 0.017 | |
| ribonucleotide catabolic process | GO:0009261 | 109 | 0.017 | |
| nucleoside catabolic process | GO:0009164 | 112 | 0.017 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.017 | |
| regulation of wnt signaling pathway | GO:0030111 | 68 | 0.017 | |
| spindle assembly | GO:0051225 | 80 | 0.017 | |
| purine ribonucleotide metabolic process | GO:0009150 | 145 | 0.017 | |
| positive regulation of growth | GO:0045927 | 75 | 0.017 | |
| chromosome separation | GO:0051304 | 42 | 0.017 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.016 | |
| single organism catabolic process | GO:0044712 | 228 | 0.016 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 119 | 0.016 | |
| nucleotide metabolic process | GO:0009117 | 161 | 0.016 | |
| positive regulation of transport | GO:0051050 | 92 | 0.016 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 16 | 0.016 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.016 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.016 | |
| positive regulation of catalytic activity | GO:0043085 | 118 | 0.016 | Human |
| purine nucleotide catabolic process | GO:0006195 | 109 | 0.016 | |
| protein maturation | GO:0051604 | 71 | 0.015 | |
| sex differentiation | GO:0007548 | 81 | 0.015 | |
| maintenance of location in cell | GO:0051651 | 28 | 0.015 | |
| entry into cell of other organism involved in symbiotic interaction | GO:0051806 | 3 | 0.015 | |
| response to organic substance | GO:0010033 | 284 | 0.015 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.015 | |
| nuclear transcribed mrna catabolic process deadenylation dependent decay | GO:0000288 | 14 | 0.015 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 119 | 0.015 | |
| regulation of protein processing | GO:0070613 | 32 | 0.015 | |
| positive regulation of catabolic process | GO:0009896 | 105 | 0.014 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.014 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.014 | |
| purine ribonucleoside metabolic process | GO:0046128 | 127 | 0.014 | |
| regulation of intracellular transport | GO:0032386 | 64 | 0.014 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.013 | |
| regulation of smoothened signaling pathway | GO:0008589 | 28 | 0.013 | |
| negative regulation of proteolysis | GO:0045861 | 31 | 0.013 | |
| response to endogenous stimulus | GO:0009719 | 119 | 0.013 | |
| negative regulation of sequence specific dna binding transcription factor activity | GO:0043433 | 4 | 0.013 | |
| taxis | GO:0042330 | 304 | 0.013 | |
| response to heat | GO:0009408 | 63 | 0.013 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.013 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 120 | 0.012 | |
| mitotic dna damage checkpoint | GO:0044773 | 74 | 0.012 | |
| chromatin modification | GO:0016568 | 147 | 0.012 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.012 | |
| anterior posterior axis specification embryo | GO:0008595 | 103 | 0.012 | |
| morphogenesis of an epithelium | GO:0002009 | 276 | 0.012 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.012 | |
| regulation of protein complex assembly | GO:0043254 | 42 | 0.012 | |
| tube development | GO:0035295 | 244 | 0.011 | |
| membrane organization | GO:0061024 | 112 | 0.011 | |
| carbohydrate derivative catabolic process | GO:1901136 | 118 | 0.011 | |
| response to nutrient levels | GO:0031667 | 114 | 0.011 | |
| dna integrity checkpoint | GO:0031570 | 81 | 0.011 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 69 | 0.011 | |
| anterior posterior pattern specification | GO:0009952 | 136 | 0.011 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.011 | |
| mrna catabolic process | GO:0006402 | 33 | 0.011 | |
| regulation of apoptotic process | GO:0042981 | 130 | 0.011 | |
| response to other organism | GO:0051707 | 293 | 0.011 | |
| mrna cis splicing via spliceosome | GO:0045292 | 1 | 0.011 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.011 | |
| dendrite development | GO:0016358 | 204 | 0.011 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.011 | |
| response to radiation | GO:0009314 | 155 | 0.010 | |
| regulation of ras protein signal transduction | GO:0046578 | 93 | 0.010 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.010 | |
| regulation of localization | GO:0032879 | 275 | 0.010 | |
| regulation of notch signaling pathway | GO:0008593 | 100 | 0.010 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.010 | |
| segmentation | GO:0035282 | 207 | 0.010 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 38 | 0.010 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 24 | 0.010 | |
| response to organic cyclic compound | GO:0014070 | 89 | 0.010 | |
