Drosophila melanogaster

25 known processes

defl (Dmel_CG18176)

deflated

(Aliases: CG18176,Dmel\CG18176)

defl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.473
histone acetylationGO:0016573380.365
rna processingGO:00063961470.313
peptidyl amino acid modificationGO:00181931050.250
regionalizationGO:00030024160.232
ovarian follicle cell developmentGO:00307072480.224
chromatin organizationGO:00063252070.209
oocyte axis specificationGO:00073091080.187
cellular protein modification processGO:00064644380.170
oocyte fate determinationGO:0030716270.170
columnar cuboidal epithelial cell developmentGO:00020662490.168
protein acylationGO:0043543420.160
peptidyl lysine acetylationGO:0018394390.156
response to ionizing radiationGO:0010212320.146
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.143
vesicle mediated transportGO:00161923810.126
Worm
chorion containing eggshell formationGO:00073041050.124
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.123
peptidyl lysine modificationGO:0018205570.121
transcription from rna polymerase ii promoterGO:00063663680.121
negative regulation of gene expressionGO:00106293870.121
double strand break repairGO:0006302260.120
endocytosisGO:00068973100.115
Worm
transmembrane transportGO:00550851390.114
ncrna 3 end processingGO:0043628170.111
response to abiotic stimulusGO:00096283410.110
protein modification processGO:00362114380.105
epithelial cell developmentGO:00020642740.105
immune system developmentGO:0002520570.103
regulation of autophagyGO:0010506620.097
internal protein amino acid acetylationGO:0006475380.094
aromatic compound catabolic processGO:00194391660.092
recombinational repairGO:0000725130.091
cellular nitrogen compound catabolic processGO:00442701650.090
immune system processGO:00023763470.089
cellular macromolecule localizationGO:00707272200.089
snrna processingGO:0016180140.088
cellular component assembly involved in morphogenesisGO:00109271510.086
positive regulation of nitrogen compound metabolic processGO:00511733540.082
positive regulation of macromolecule metabolic processGO:00106044050.079
eye morphogenesisGO:00485922600.077
cellular response to dna damage stimulusGO:00069742230.073
positive regulation of transcription dna templatedGO:00458932660.073
single organism cellular localizationGO:19025801800.073
columnar cuboidal epithelial cell differentiationGO:00020652560.072
cellular ketone metabolic processGO:0042180240.066
snrna metabolic processGO:0016073140.065
positive regulation of biosynthetic processGO:00098913160.061
posttranscriptional gene silencingGO:0016441460.061
regulation of cellular ketone metabolic processGO:001056530.061
regulation of vesicle mediated transportGO:0060627590.061
protein acetylationGO:0006473390.060
regulation of cellular amine metabolic processGO:003323830.058
positive regulation of catabolic processGO:00098961050.058
chemical homeostasisGO:0048878920.056
organic cyclic compound catabolic processGO:19013611680.055
positive regulation of response to stimulusGO:00485843230.054
internal peptidyl lysine acetylationGO:0018393380.054
chromatin modificationGO:00165681470.053
catabolic processGO:00090564090.052
double strand break repair via homologous recombinationGO:0000724130.052
histone modificationGO:00165701060.051
single organism intracellular transportGO:19025822070.051
epithelial cell differentiationGO:00308553220.051
dna repairGO:0006281540.050
mrna catabolic processGO:0006402330.050
meiotic cell cycle processGO:19030461320.050
oocyte dorsal ventral axis specificationGO:0007310340.050
dna recombinationGO:0006310320.049
regulation of transcription from rna polymerase ii promoterGO:00063573780.048
regulation of cell deathGO:00109411730.047
mrna metabolic processGO:00160711240.047
autophagyGO:00069141080.046
oocyte differentiationGO:00099941450.046
germarium derived oocyte fate determinationGO:0007294260.045
hematopoietic or lymphoid organ developmentGO:0048534570.045
rna catabolic processGO:0006401370.045
innate immune responseGO:00450871440.045
organic substance catabolic processGO:19015753080.045
oocyte developmentGO:00485991240.044
dorsal ventral axis specificationGO:0009950660.044
eye pigment metabolic processGO:0042441330.044
regulation of immune system processGO:00026821760.044
rna localizationGO:00064031150.041
posttranscriptional regulation of gene expressionGO:00106081450.041
macromolecular complex assemblyGO:00650032560.041
protein localizationGO:00081042840.040
nucleobase containing compound catabolic processGO:00346551650.040
eye developmentGO:00016543230.040
cellular catabolic processGO:00442483720.039
covalent chromatin modificationGO:00165691060.038
negative regulation of cell communicationGO:00106482230.037
enzyme linked receptor protein signaling pathwayGO:00071671790.037
cytoplasmic transportGO:00164821300.036
regulation of cellular amino acid metabolic processGO:000652100.036
negative regulation of cell deathGO:0060548810.036
dorsal ventral pattern formationGO:00099531330.036
imaginal disc derived wing vein specificationGO:0007474480.036
intracellular protein transportGO:00068861040.036
snrna 3 end processingGO:0034472140.035
sensory organ morphogenesisGO:00905962600.034
positive regulation of gene expressionGO:00106282900.034
oxoacid metabolic processGO:00434361030.034
oocyte constructionGO:00073081120.034
negative regulation of signal transductionGO:00099682060.033
cellular protein localizationGO:00346131600.032
ras protein signal transductionGO:0007265880.032
homeostatic processGO:00425921990.031
establishment of localization in cellGO:00516494020.031
regulation of cellular component biogenesisGO:00440872010.031
pigment metabolic process involved in developmental pigmentationGO:0043324330.031
immune responseGO:00069552460.031
organic acid metabolic processGO:00060821030.030
response to oxygen containing compoundGO:19017002000.030
cellular macromolecular complex assemblyGO:00346221530.030
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.030
cellular macromolecule catabolic processGO:00442651360.029
positive regulation of cellular amino acid metabolic processGO:004576400.029
programmed cell deathGO:00125012570.029
regulation of mrna metabolic processGO:1903311720.028
extracellular structure organizationGO:0043062460.028
small molecule metabolic processGO:00442813050.028
rna transportGO:0050658460.028
gene silencing by rnaGO:0031047570.027
positive regulation of mrna processingGO:005068540.027
heterocycle catabolic processGO:00467001660.027
camera type eye developmentGO:004301040.027
actin cytoskeleton organizationGO:00300362060.027
defense responseGO:00069523000.027
positive regulation of macromolecule biosynthetic processGO:00105572830.026
positive regulation of transportGO:0051050920.026
establishment of protein localizationGO:00451841630.026
embryonic pattern specificationGO:00098801740.025
protein transportGO:00150311550.025
membrane organizationGO:00610241120.025
stem cell differentiationGO:00488631170.025
positive regulation of signalingGO:00230562430.025
mrna processingGO:00063971040.024
actin filament based processGO:00300292200.024
response to radiationGO:00093141550.024
negative regulation of multicellular organismal processGO:00512411420.024
apoptotic processGO:00069151590.024
response to alcoholGO:0097305950.024
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
transition metal ion homeostasisGO:0055076170.023
tissue morphogenesisGO:00487292970.023
positive regulation of nucleic acid templated transcriptionGO:19035082660.023
meiotic cell cycleGO:00513211710.023
regulation of gene expression epigeneticGO:00400291280.023
positive regulation of cellular catabolic processGO:0031331950.023
segmentationGO:00352822070.023
regulation of protein metabolic processGO:00512462560.023
neuron projection guidanceGO:00974852410.023
dna biosynthetic processGO:0071897240.022
regulation of cellular localizationGO:00603411360.022
regulation of hormone levelsGO:0010817400.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
eggshell chorion gene amplificationGO:000730790.022
regulation of apoptotic processGO:00429811300.022
single organism biosynthetic processGO:00447112060.022
amine metabolic processGO:0009308120.022
cellular response to organic substanceGO:00713101320.022
response to organic substanceGO:00100332840.022
ion transmembrane transportGO:00342201220.022
negative regulation of nitrogen compound metabolic processGO:00511722650.022
regulation of molecular functionGO:00650092170.022
nucleobase containing compound transportGO:0015931560.022
chromatin remodelingGO:0006338720.021
axon guidanceGO:00074112330.021
regulation of mitotic cell cycle phase transitionGO:19019901300.021
cellular amine metabolic processGO:0044106120.021
protein ubiquitinationGO:0016567700.021
male gamete generationGO:00482322010.021
negative regulation of response to stimulusGO:00485852580.021
regulation of cell cycleGO:00517262910.021
lateral inhibitionGO:00463312060.021
cell migrationGO:00164772380.021
regulation of immune responseGO:00507761180.021
defense response to bacteriumGO:00427421780.020
cellular response to chemical stimulusGO:00708871990.020
imaginal disc derived wing vein morphogenesisGO:0008586440.020
nuclear divisionGO:00002803320.020
intracellular transportGO:00469072280.020
body morphogenesisGO:001017120.020
Worm
hemopoiesisGO:0030097460.020
regulation of response to stressGO:00801342000.020
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.020
mitotic cell cycle phase transitionGO:00447721380.020
histone h4 k16 acetylationGO:004398440.020
regulation of programmed cell deathGO:00430671520.019
nuclear transportGO:0051169720.019
female meiotic divisionGO:0007143700.019
regulation of g1 s transition of mitotic cell cycleGO:2000045230.019
positive regulation of cellular biosynthetic processGO:00313283160.019
spermatid developmentGO:0007286980.019
regulation of catabolic processGO:00098941700.019
ribonucleoside metabolic processGO:00091191270.019
germarium derived egg chamber formationGO:00072931010.019
small gtpase mediated signal transductionGO:0007264880.019
tissue migrationGO:00901301550.018
protein dna complex assemblyGO:0065004630.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
eggshell formationGO:00307031050.018
negative regulation of rna biosynthetic processGO:19026792400.018
positive regulation of cellular amine metabolic processGO:003324000.018
positive regulation of mapk cascadeGO:0043410630.018
regulation of transportGO:00510491810.018
stem cell developmentGO:0048864790.018
macromolecule catabolic processGO:00090571610.018
wing disc morphogenesisGO:00074723440.018
nuclear dna replicationGO:003326010.018
negative regulation of rna metabolic processGO:00512532510.018
axis specificationGO:00097981670.017
ion homeostasisGO:0050801550.017
cell cycle phase transitionGO:00447701400.017
regulation of cellular catabolic processGO:00313291570.017
cell deathGO:00082192790.017
positive regulation of rna biosynthetic processGO:19026802660.017
embryo development ending in birth or egg hatchingGO:00097921520.017
Worm
response to external biotic stimulusGO:00432072930.017
anterior posterior pattern specificationGO:00099521360.017
cellular amino acid metabolic processGO:0006520610.017
positive regulation of nucleotide metabolic processGO:0045981550.016
regulation of mitotic cell cycleGO:00073461900.016
mating behaviorGO:00076171060.016
carboxylic acid metabolic processGO:0019752920.016
appendage morphogenesisGO:00351073970.016
single organism membrane organizationGO:0044802930.016
stem cell maintenanceGO:0019827670.016
positive regulation of rna metabolic processGO:00512542710.016
regulation of membrane potentialGO:0042391350.016
regulation of mrna processingGO:0050684710.016
defense response to other organismGO:00985422250.016
regulation of localizationGO:00328792750.016
intracellular signal transductionGO:00355563000.015
hematopoietic progenitor cell differentiationGO:000224410.015
protein modification by small protein conjugation or removalGO:00706471060.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
localization of cellGO:00516742570.015
protein dna complex subunit organizationGO:0071824860.014
positive regulation of cellular component organizationGO:00511301560.014
establishment of rna localizationGO:0051236470.014
lysosomal transportGO:0007041130.014
compound eye morphogenesisGO:00017452490.014
mitotic nuclear divisionGO:00070672130.014
positive regulation of intracellular signal transductionGO:19025331160.014
negative regulation of cellular metabolic processGO:00313243820.014
regulation of cellular response to stressGO:0080135890.014
determination of left right symmetryGO:000736890.014
positive regulation of protein metabolic processGO:00512471280.014
cell proliferationGO:00082832990.013
meiotic nuclear divisionGO:00071261510.013
erbb signaling pathwayGO:0038127580.013
gtp metabolic processGO:0046039720.013
response to ecdysoneGO:0035075340.013
response to sterolGO:0036314340.013
chromosome segregationGO:00070591570.013
receptor mediated endocytosisGO:0006898210.013
Worm
positive regulation of signal transductionGO:00099672230.013
negative regulation of developmental processGO:00510932010.012
mesenchymal cell developmentGO:001403110.012
regulation of nervous system developmentGO:00519602480.012
organelle fissionGO:00482853400.012
rna 3 end processingGO:0031123450.012
cell agingGO:000756920.012
response to other organismGO:00517072930.012
epithelial cell migrationGO:00106311480.012
positive regulation of cellular component biogenesisGO:0044089800.012
gene silencingGO:00164581380.012
ecdysis chitin based cuticleGO:001899080.012
cellular homeostasisGO:0019725800.012
transcription initiation from rna polymerase ii promoterGO:0006367250.012
regulation of notch signaling pathwayGO:00085931000.012
regulation of protein modification processGO:00313991120.012
cell cycle dna replicationGO:0044786230.012
negative regulation of growthGO:0045926840.011
phosphorylationGO:00163102940.011
deathGO:00162652840.011
response to monosaccharideGO:003428440.011
telencephalon developmentGO:002153720.011
spermatogenesisGO:00072832000.011
positive regulation of phosphorus metabolic processGO:00105621390.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
positive regulation of cellular protein metabolic processGO:00322701180.011
photoreceptor cell developmentGO:0042461960.011
positive regulation of multicellular organismal processGO:00512401430.011
negative regulation of cell cycleGO:00457861160.011
protein localization to organelleGO:0033365820.011
dna endoreduplicationGO:0042023220.011
negative regulation of receptor activityGO:200027230.011
regulation of cellular protein metabolic processGO:00322682430.011
embryonic organ developmentGO:0048568500.011
positive regulation of catalytic activityGO:00430851180.010
positive regulation of immune system processGO:0002684680.010
immune response regulating signaling pathwayGO:000276420.010
purine containing compound catabolic processGO:00725231120.010
single organism catabolic processGO:00447122280.010
negative regulation of biosynthetic processGO:00098902770.010
signal transduction by phosphorylationGO:00230141070.010
protein complex assemblyGO:00064612000.010
establishment or maintenance of cell polarityGO:00071631670.010
negative regulation of cellular biosynthetic processGO:00313272770.010
chaeta developmentGO:0022416970.010
cell fate specification involved in pattern specificationGO:006057380.010

defl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.070
cardiovascular system diseaseDOID:128700.036
disease of anatomical entityDOID:700.036
disease of cellular proliferationDOID:1456600.032
cancerDOID:16200.032
organ system cancerDOID:005068600.032
inherited metabolic disorderDOID:65500.019
acquired metabolic diseaseDOID:006015800.017