Drosophila melanogaster

26 known processes

mxc (Dmel_CG12124)

multi sex combs

(Aliases: Dmel\CG12124,Dmel_CG12058,l(1)mbn,CG12058,CG12124)

mxc biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna conformation changeGO:00711031050.969
regionalizationGO:00030024160.966
chromatin organizationGO:00063252070.958
imaginal disc derived appendage morphogenesisGO:00351143950.951
regulation of neurogenesisGO:00507671580.945
spermatogenesisGO:00072832000.898
appendage developmentGO:00487364010.889
gonad developmentGO:0008406500.843
male gamete generationGO:00482322010.831
regulation of neuron differentiationGO:00456641030.829
cell fate specificationGO:0001708710.822
sex differentiationGO:0007548810.815
imaginal disc derived appendage developmentGO:00487373990.812
reproductive structure developmentGO:0048608740.807
reproductive system developmentGO:0061458740.763
meiotic cell cycleGO:00513211710.752
chromosome organizationGO:00512763600.740
meiotic nuclear divisionGO:00071261510.737
regulation of neuron projection developmentGO:0010975690.735
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.733
axon developmentGO:00615642970.714
single organism cellular localizationGO:19025801800.711
regulation of transcription from rna polymerase ii promoterGO:00063573780.691
tissue morphogenesisGO:00487292970.690
determination of imaginal disc primordiumGO:0007445110.654
cellular protein modification processGO:00064644380.648
rna splicing via transesterification reactionsGO:0000375730.622
regulation of cell proliferationGO:00421271630.612
anterior posterior pattern specificationGO:00099521360.604
development of primary sexual characteristicsGO:0045137500.583
dna metabolic processGO:00062592270.579
cell motilityGO:00488702510.542
chromatin modificationGO:00165681470.499
transcription from rna polymerase ii promoterGO:00063663680.482
axon guidanceGO:00074112330.465
organelle fissionGO:00482853400.458
negative regulation of rna metabolic processGO:00512532510.456
appendage morphogenesisGO:00351073970.439
dna packagingGO:0006323910.439
pole plasm assemblyGO:0007315610.435
chromatin remodelingGO:0006338720.424
chemotaxisGO:00069352490.423
negative regulation of nucleobase containing compound metabolic processGO:00459342610.423
central nervous system developmentGO:00074172010.418
regulation of photoreceptor cell differentiationGO:0046532340.418
neuron projection guidanceGO:00974852410.415
regulation of cell developmentGO:00602842150.409
negative regulation of nucleic acid templated transcriptionGO:19035072400.407
oocyte differentiationGO:00099941450.404
dendrite morphogenesisGO:00488131990.404
axonogenesisGO:00074092900.402
regulation of r7 cell differentiationGO:0045676150.378
columnar cuboidal epithelial cell developmentGO:00020662490.374
negative regulation of meiotic cell cycleGO:005144720.369
stem cell differentiationGO:00488631170.359
post embryonic appendage morphogenesisGO:00351203850.355
nuclear divisionGO:00002803320.355
cell proliferationGO:00082832990.352
regulation of protein modification processGO:00313991120.341
regulation of embryonic developmentGO:0045995680.337
macromolecular complex assemblyGO:00650032560.318
regulation of growthGO:00400082330.318
sensory organ morphogenesisGO:00905962600.311
determination of genital disc primordiumGO:0035225100.285
regulation of anatomical structure morphogenesisGO:00226032420.281
cell divisionGO:00513012480.278
muscle structure developmentGO:00610612240.271
ovarian follicle cell developmentGO:00307072480.271
histone modificationGO:00165701060.270
cell maturationGO:00484691440.240
cytokinesisGO:0000910900.239
genitalia developmentGO:0048806260.238
imaginal disc derived leg morphogenesisGO:0007480800.238
segmentationGO:00352822070.220
meiotic cell cycle processGO:19030461320.211
leg disc developmentGO:0035218920.210
axis specificationGO:00097981670.210
positive regulation of gene expressionGO:00106282900.209
growthGO:00400073590.208
cellular macromolecule localizationGO:00707272200.206
protein complex assemblyGO:00064612000.204
negative regulation of neuroblast proliferationGO:0007406270.196
hemocyte differentiationGO:0042386380.186
dendrite developmentGO:00163582040.181
regulation of cell fate specificationGO:0042659270.180
homeostatic processGO:00425921990.175
eye antennal disc developmentGO:0035214600.171
synapse assemblyGO:00074161430.171
regulation of cell differentiationGO:00455953020.168
regulation of multicellular organismal developmentGO:20000264140.165
taxisGO:00423303040.164
regulation of nucleocytoplasmic transportGO:0046822350.163
imaginal disc derived wing vein specificationGO:0007474480.159
anterior posterior axis specification embryoGO:00085951030.157
negative regulation of transcription dna templatedGO:00458922370.155
rna splicingGO:0008380830.153
cell cell signaling involved in cell fate commitmentGO:00451682100.152
tube developmentGO:00352952440.149
negative regulation of cell communicationGO:00106482230.149
negative regulation of cell proliferationGO:0008285690.148
morphogenesis of an epitheliumGO:00020092760.147
gland developmentGO:00487321910.145
regulation of cell morphogenesisGO:00226041630.142
protein localizationGO:00081042840.141
cardioblast cell fate specificationGO:004268590.135
covalent chromatin modificationGO:00165691060.134
photoreceptor cell differentiationGO:00465301700.132
eye developmentGO:00016543230.129
larval developmentGO:00021641040.128
embryonic morphogenesisGO:00485982060.128
protein transportGO:00150311550.127
embryonic pattern specificationGO:00098801740.125
regulation of nervous system developmentGO:00519602480.124
regulation of protein transportGO:0051223570.123
response to external biotic stimulusGO:00432072930.122
positive regulation of nucleobase containing compound metabolic processGO:00459353320.122
compound eye photoreceptor cell differentiationGO:00017511400.121
signal transduction by phosphorylationGO:00230141070.120
head developmentGO:00603221350.119
germarium derived egg chamber formationGO:00072931010.118
regulation of localizationGO:00328792750.116
regulation of transportGO:00510491810.116
positive regulation of macromolecule biosynthetic processGO:00105572830.115
protein import into nucleusGO:0006606510.114
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.113
cellular response to dna damage stimulusGO:00069742230.112
male meiosisGO:0007140520.111
leg disc morphogenesisGO:0007478800.110
regulation of cell cycleGO:00517262910.106
negative regulation of signal transductionGO:00099682060.106
imaginal disc derived wing morphogenesisGO:00074763370.105
negative regulation of signalingGO:00230572190.105
negative regulation of cellular biosynthetic processGO:00313272770.104
chromosome condensationGO:0030261410.103
immune system processGO:00023763470.101
positive regulation of growthGO:0045927750.099
protein localization to nucleusGO:0034504550.098
neuron fate commitmentGO:0048663500.098
positive regulation of cellular biosynthetic processGO:00313283160.094
mitochondrion organizationGO:0007005650.091
regulation of cellular localizationGO:00603411360.090
positive regulation of response to stimulusGO:00485843230.089
embryonic hindgut morphogenesisGO:0048619480.089
protein modification processGO:00362114380.088
mrna splicing via spliceosomeGO:0000398730.088
regulation of intracellular transportGO:0032386640.088
positive regulation of macromolecule metabolic processGO:00106044050.087
lipid localizationGO:0010876540.087
blastoderm segmentationGO:00073501590.086
regulation of cell fate commitmentGO:0010453290.085
biological adhesionGO:00226101380.084
branching morphogenesis of an epithelial tubeGO:0048754450.082
positive regulation of cellular component organizationGO:00511301560.082
compound eye morphogenesisGO:00017452490.082
oocyte developmentGO:00485991240.082
negative regulation of nitrogen compound metabolic processGO:00511722650.080
positive regulation of cell developmentGO:0010720610.080
cell migrationGO:00164772380.080
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.079
regulation of cellular response to stressGO:0080135890.079
cellular response to extracellular stimulusGO:0031668640.079
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.078
digestive tract developmentGO:00485651490.077
imaginal disc derived leg segmentationGO:0036011260.075
compound eye developmentGO:00487493070.075
wing disc morphogenesisGO:00074723440.074
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.073
positive regulation of neurogenesisGO:0050769410.072
positive regulation of rna metabolic processGO:00512542710.071
localization of cellGO:00516742570.071
asymmetric cell divisionGO:0008356370.070
cellular response to organic substanceGO:00713101320.070
establishment of localization in cellGO:00516494020.069
digestive tract morphogenesisGO:00485461270.069
regulation of pathway restricted smad protein phosphorylationGO:006039310.068
protein targetingGO:0006605640.067
carbohydrate derivative metabolic processGO:19011352170.066
negative regulation of rna biosynthetic processGO:19026792400.066
regulation of cell morphogenesis involved in differentiationGO:0010769610.065
positive regulation of transportGO:0051050920.064
endocytosisGO:00068973100.064
dorsal appendage formationGO:0046843470.064
regulation of phosphate metabolic processGO:00192202100.063
regulation of cellular component biogenesisGO:00440872010.062
response to alcoholGO:0097305950.059
response to oxygen containing compoundGO:19017002000.058
negative regulation of biosynthetic processGO:00098902770.058
cell deathGO:00082192790.058
eye morphogenesisGO:00485922600.058
protein localization to organelleGO:0033365820.058
r7 cell differentiationGO:0045466430.057
germarium derived female germ line cyst encapsulationGO:003070880.057
segment polarity determinationGO:0007367250.057
anterior posterior axis specificationGO:00099481090.056
regulation of phosphorylationGO:00423251470.056
membrane organizationGO:00610241120.055
body morphogenesisGO:001017120.055
establishment of protein localization to organelleGO:0072594620.055
organic substance catabolic processGO:19015753080.054
protein targeting to nucleusGO:0044744510.054
oocyte anterior posterior axis specificationGO:0007314720.054
developmental growthGO:00485892800.053
germline stem cell asymmetric divisionGO:0098728150.053
negative regulation of response to stimulusGO:00485852580.052
phosphorylationGO:00163102940.050
protein dna complex subunit organizationGO:0071824860.050
alternative mrna splicing via spliceosomeGO:0000380600.050
neuron fate specificationGO:0048665120.049
cardiovascular system developmentGO:0072358820.048
single organism behaviorGO:00447083910.048
imaginal disc derived leg joint morphogenesisGO:0016348150.048
regulation of heart inductionGO:009038130.048
glial cell migrationGO:0008347310.048
regulation of stress activated protein kinase signaling cascadeGO:0070302420.047
regulation of pole plasm oskar mrna localizationGO:0007317270.047
negative regulation of multicellular organismal processGO:00512411420.047
eye photoreceptor cell differentiationGO:00017541450.047
embryonic hemopoiesisGO:0035162260.046
cellular macromolecular complex assemblyGO:00346221530.046
positive regulation of developmental processGO:00510941430.045
male sex differentiationGO:0046661250.045
catabolic processGO:00090564090.045
mitotic spindle organizationGO:00070522200.044
establishment of protein localizationGO:00451841630.044
internal peptidyl lysine acetylationGO:0018393380.044
heart field specificationGO:000312800.043
regulation of meiotic cell cycleGO:005144590.043
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.042
chromatin mediated maintenance of transcriptionGO:004809670.042
regulation of mrna splicing via spliceosomeGO:0048024640.041
ribonucleoside catabolic processGO:00424541120.041
negative regulation of neurogenesisGO:0050768530.041
regulation of meiosisGO:004002030.041
eye photoreceptor cell fate commitmentGO:0042706370.040
female sex differentiationGO:0046660200.040
regulation of cell cycle processGO:00105641810.040
cellular homeostasisGO:0019725800.039
protein importGO:0017038550.039
spindle organizationGO:00070512530.039
regulation of epithelial cell differentiationGO:003085640.038
response to extracellular stimulusGO:00099911160.038
vesicle mediated transportGO:00161923810.038
regulation of phosphorus metabolic processGO:00511742100.038
immune response activating signal transductionGO:000275720.038
regulation of organ morphogenesisGO:2000027780.038
wing disc pattern formationGO:0035222660.038
tube morphogenesisGO:00352391910.037
stress activated mapk cascadeGO:0051403520.037
transcription initiation from rna polymerase ii promoterGO:0006367250.037
instar larval developmentGO:0002168550.037
gliogenesisGO:0042063800.037
single organism membrane organizationGO:0044802930.037
single organism intracellular transportGO:19025822070.037
regulation of cell projection organizationGO:0031344920.037
positive regulation of r7 cell differentiationGO:004567870.036
response to nutrient levelsGO:00316671140.035
embryonic axis specificationGO:00005781070.035
specification of organ identityGO:001009230.034
regulation of cell divisionGO:0051302720.034
stem cell developmentGO:0048864790.034
jnk cascadeGO:0007254500.033
positive regulation of nucleic acid templated transcriptionGO:19035082660.033
mitotic chromosome condensationGO:0007076220.033
regulation of developmental growthGO:00486381740.033
female gonad developmentGO:0008585120.033
positive regulation of transcription dna templatedGO:00458932660.033
appendage segmentationGO:0035285260.033
negative regulation of cell developmentGO:0010721620.033
positive regulation of mapk cascadeGO:0043410630.032
programmed cell deathGO:00125012570.032
cellular response to chemical stimulusGO:00708871990.032
mrna processingGO:00063971040.032
chorion containing eggshell formationGO:00073041050.031
photoreceptor cell developmentGO:0042461960.031
stress activated protein kinase signaling cascadeGO:0031098550.031
mesodermal cell fate specificationGO:000750120.031
regulation of epithelial cell proliferationGO:005067840.030
neuron maturationGO:0042551310.030
deathGO:00162652840.030
malpighian tubule developmentGO:0072002640.030
regulation of organelle organizationGO:00330431960.030
positive regulation of biosynthetic processGO:00098913160.029
cellular response to oxygen containing compoundGO:1901701790.029
photoreceptor cell fate commitmentGO:0046552410.029
regulation of cell cycle g1 s phase transitionGO:1902806230.029
positive regulation of cell deathGO:0010942690.029
cell chemotaxisGO:006032660.029
organic substance transportGO:00717022570.029
cellular response to nutrient levelsGO:0031669620.028
intracellular receptor signaling pathwayGO:0030522190.028
embryo development ending in birth or egg hatchingGO:00097921520.028
spermatid differentiationGO:00485151140.028
gland morphogenesisGO:00226121450.028
tripartite regional subdivisionGO:00073511030.028
chemical homeostasisGO:0048878920.028
matingGO:00076181200.028
sister chromatid segregationGO:0000819920.027
cardioblast differentiationGO:0010002200.027
morphogenesis of a branching structureGO:0001763450.027
organ inductionGO:000175930.027
terminal region determinationGO:0007362250.026
mesenchymal cell differentiationGO:004876210.026
positive regulation of intracellular signal transductionGO:19025331160.026
regulation of hemocyte differentiationGO:0045610220.026
negative regulation of phosphorus metabolic processGO:0010563450.025
positive regulation of protein transportGO:0051222370.025
eye photoreceptor cell developmentGO:0042462810.025
tissue deathGO:00162711020.025
response to biotic stimulusGO:00096072940.025
macromolecule methylationGO:0043414450.025
regulation of jnk cascadeGO:0046328400.025
negative regulation of phosphate metabolic processGO:0045936450.024
regulation of i kappab kinase nf kappab signalingGO:004312220.024
innate immune responseGO:00450871440.024
stem cell divisionGO:0017145690.024
response to radiationGO:00093141550.024
rna processingGO:00063961470.023
positive regulation of multicellular organismal processGO:00512401430.023
protein complex biogenesisGO:00702712010.022
response to hormoneGO:0009725450.022
actin filament based processGO:00300292200.022
cell cycle phase transitionGO:00447701400.022
compound eye photoreceptor developmentGO:0042051780.022
ion transportGO:00068111450.022
response to ecdysoneGO:0035075340.021
regulation of mrna metabolic processGO:1903311720.021
regulation of spindle checkpointGO:009023120.021
autophagyGO:00069141080.021
male mating behaviorGO:0060179700.021
oocyte maturationGO:000155630.021
morphogenesis of a branching epitheliumGO:0061138450.021
regulation of establishment of protein localizationGO:0070201610.021
oocyte constructionGO:00073081120.021
methylationGO:0032259470.021
carbohydrate metabolic processGO:0005975820.021
aromatic compound catabolic processGO:00194391660.021
regulation of behaviorGO:0050795750.021
histolysisGO:00075591020.021
macromolecule catabolic processGO:00090571610.020
endodermal cell differentiationGO:003598730.020
negative regulation of cellular metabolic processGO:00313243820.020
male courtship behaviorGO:0008049630.020
telencephalon developmentGO:002153720.020
regulation of actin cytoskeleton organizationGO:0032956420.020
muscle cell fate commitmentGO:0042693140.020
response to endogenous stimulusGO:00097191190.020
nuclear transportGO:0051169720.020
epithelial cell differentiationGO:00308553220.020
regulation of lipid transportGO:003236830.020
positive regulation of cell communicationGO:00106472500.020
regulation of dendrite developmentGO:0050773370.019
pole plasm rna localizationGO:0007316520.019
positive regulation of photoreceptor cell differentiationGO:0046534120.019
compound eye photoreceptor fate commitmentGO:0001752360.019
brain developmentGO:00074201200.019
negative regulation of epithelial cell proliferationGO:005068040.019
regulation of stress activated mapk cascadeGO:0032872410.019
positive regulation of phosphate metabolic processGO:00459371390.019
cell adhesionGO:00071551360.019
response to bacteriumGO:00096171980.019
development of primary female sexual characteristicsGO:0046545120.019
renal tubule developmentGO:0061326640.018
cellular response to endogenous stimulusGO:0071495800.018
epithelial cell developmentGO:00020642740.018
hindgut developmentGO:0061525580.018
positive regulation of signalingGO:00230562430.018
negative regulation of catalytic activityGO:0043086420.018
negative regulation of protein metabolic processGO:0051248850.018
positive regulation of nervous system developmentGO:0051962690.018
nuclear importGO:0051170510.018
regulation of response to external stimulusGO:00321011150.017
regulation of immune system processGO:00026821760.017
regulation of protein targetingGO:1903533290.017
regulation of alternative mrna splicing via spliceosomeGO:0000381600.017
response to abiotic stimulusGO:00096283410.017
neuroblast proliferationGO:0007405740.017
regulation of mapk cascadeGO:0043408920.017
oocyte axis specificationGO:00073091080.017
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.017
eggshell chorion assemblyGO:0007306660.017
head involutionGO:0008258350.017
regulation of rna splicingGO:0043484690.017
neuron projection extensionGO:1990138320.017
tissue migrationGO:00901301550.017
cellular protein localizationGO:00346131600.016
heart inductionGO:000312930.016
anatomical structure homeostasisGO:0060249970.016
mitotic cytokinesisGO:0000281500.016
embryonic development via the syncytial blastodermGO:00017001480.016
negative regulation of gtpase activityGO:003426010.016
single organism carbohydrate metabolic processGO:0044723720.016
lipid storageGO:0019915380.016
single organism catabolic processGO:00447122280.016
regulation of intracellular protein transportGO:0033157460.016
regulation of response to stressGO:00801342000.016
secretion by cellGO:00329401010.016
negative regulation of cell differentiationGO:00455961430.015
protein dna complex assemblyGO:0065004630.015
cell cycle comprising mitosis without cytokinesisGO:0033301250.015
cardiac cell fate commitmentGO:0060911170.015
mushroom body developmentGO:0016319700.015
r3 r4 cell fate commitmentGO:0007464100.014
purine containing compound metabolic processGO:00725211550.014
muscle organ developmentGO:00075171270.014
maintenance of gastrointestinal epitheliumGO:003027730.014
endoderm formationGO:000170630.014
regulation of nf kappab import into nucleusGO:004234510.014
positive regulation of phosphorylationGO:0042327870.014
cell growthGO:00160491080.014
negative regulation of protein phosphorylationGO:0001933170.014
regulation of vesicle mediated transportGO:0060627590.014
malpighian tubule morphogenesisGO:0007443440.014
glial cell fate determinationGO:000740330.013
positive regulation of intracellular transportGO:0032388420.013
salivary gland morphogenesisGO:00074351450.013
meiotic chromosome condensationGO:001003230.013
regulation of cellular catabolic processGO:00313291570.013
salivary gland cell autophagic cell deathGO:0035071830.013
regulation of asymmetric cell divisionGO:000978630.013
cystoblast divisionGO:0007282100.013
regulation of cytoplasmic transportGO:1903649470.013
chromatin silencingGO:0006342760.013
regulation of erk1 and erk2 cascadeGO:0070372390.013
male gonad developmentGO:000858490.013
mitotic nuclear divisionGO:00070672130.013
mating behaviorGO:00076171060.013
nucleobase containing compound catabolic processGO:00346551650.012
developmental programmed cell deathGO:00106231380.012
positive regulation of mitotic cell cycleGO:0045931340.012
response to organic cyclic compoundGO:0014070890.012
dna dependent dna replicationGO:0006261170.012
positive regulation of protein metabolic processGO:00512471280.012
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.012
cell fate commitment involved in pattern specificationGO:0060581310.012
germ line stem cell divisionGO:0042078250.012
compound eye cone cell differentiationGO:0042675130.012
dorsal closure leading edge cell differentiationGO:004666320.012
organic cyclic compound catabolic processGO:19013611680.012
response to organic substanceGO:00100332840.012
lipid metabolic processGO:00066291210.012
negative regulation of gene expressionGO:00106293870.012
regulation of cardioblast cell fate specificationGO:004268680.012
regulation of protein localization to nucleusGO:1900180290.012
multi organism behaviorGO:00517051750.012
dna templated transcription initiationGO:0006352250.012
negative regulation of neural precursor cell proliferationGO:2000178270.011
cell fate determinationGO:0001709910.011
torso signaling pathwayGO:0008293210.011
positive regulation of apoptotic processGO:0043065470.011
regulation of cellular protein metabolic processGO:00322682430.011
negative regulation of cyclin dependent protein serine threonine kinase activityGO:004573610.011
response to lipidGO:0033993380.011
multicellular organism growthGO:0035264460.011
determination of dorsal ventral asymmetryGO:004826230.011
mitochondrial membrane organizationGO:000700630.011
regulation of protein complex assemblyGO:0043254420.011
digestive system developmentGO:00551231490.011
phagocytosisGO:00069092150.011
positive regulation of immune system processGO:0002684680.011
cytoplasmic transportGO:00164821300.010
positive regulation of rna biosynthetic processGO:19026802660.010
negative regulation of macromolecule biosynthetic processGO:00105582700.010
negative regulation of stem cell differentiationGO:200073780.010
protein polymerizationGO:0051258420.010
olfactory behaviorGO:0042048970.010
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:190216610.010

mxc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
meningiomaDOID:356500.018
central nervous system cancerDOID:362000.018
familial meningiomaDOID:458600.018
cancerDOID:16200.018
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.018
nervous system cancerDOID:309300.018