IMP: Integrative Multi-species Prediction

Drosophila melanogaster

87 known processes

CTCF (Dmel_CG8591)

CG8591 gene product from transcript CG8591-RA

(Aliases: dCTCF,Dmel\CG8591,CG8591)

FLYBASE: FBgn0035769
Entrez: 38817
UniProtKB: Q9VS55

Process Predictions
Disease Predictions

CTCF biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
negative regulation of gene expression epigenetic	GO:0045814	77	1.000
chromatin silencing	GO:0006342	76	1.000
gene silencing	GO:0016458	138	1.000
negative regulation of biosynthetic process	GO:0009890	277	0.999
negative regulation of transcription dna templated	GO:0045892	237	0.999
regulation of gene expression epigenetic	GO:0040029	128	0.999
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.999
negative regulation of rna metabolic process	GO:0051253	251	0.999
negative regulation of cellular biosynthetic process	GO:0031327	277	0.999
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.998
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.997
negative regulation of rna biosynthetic process	GO:1902679	240	0.996
negative regulation of gene expression	GO:0010629	387	0.993
heterochromatin organization	GO:0070828	25	0.989
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.988
chromosome organization	GO:0051276	360	0.975
negative regulation of cellular metabolic process	GO:0031324	382	0.968
positive regulation of rna metabolic process	GO:0051254	271	0.959	Human Mouse
transcription from rna polymerase ii promoter	GO:0006366	368	0.912	Human Mouse
positive regulation of transcription dna templated	GO:0045893	266	0.899	Human Mouse
chromatin remodeling	GO:0006338	72	0.883
positive regulation of macromolecule metabolic process	GO:0010604	405	0.866	Human Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.856	Human Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.845
chromatin organization	GO:0006325	207	0.826	Human Mouse
regulation of chromatin silencing	GO:0031935	36	0.785
response to external biotic stimulus	GO:0043207	293	0.781
positive regulation of rna biosynthetic process	GO:1902680	266	0.780	Human Mouse
positive regulation of gene expression	GO:0010628	290	0.773	Human Mouse
protein acetylation	GO:0006473	39	0.763	Mouse
regulation of gene silencing	GO:0060968	63	0.744
meiotic nuclear division	GO:0007126	151	0.721
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.713	Human Mouse
single organism behavior	GO:0044708	391	0.709
embryonic morphogenesis	GO:0048598	206	0.703
chromatin modification	GO:0016568	147	0.636	Human Mouse
positive regulation of biosynthetic process	GO:0009891	316	0.630	Human Mouse
organelle fission	GO:0048285	340	0.612
taxis	GO:0042330	304	0.580
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.579	Human Mouse
positive regulation of cellular biosynthetic process	GO:0031328	316	0.562	Human Mouse
heterochromatin organization involved in chromatin silencing	GO:0070868	9	0.476
gene silencing by rna	GO:0031047	57	0.448
histone modification	GO:0016570	106	0.428	Human Mouse
response to biotic stimulus	GO:0009607	294	0.426
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.404	Human Mouse
tube development	GO:0035295	244	0.401
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.397	Human Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.368
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.351	Human Mouse
digestive tract morphogenesis	GO:0048546	127	0.345
regulation of heterochromatin assembly	GO:0031445	8	0.333
dna metabolic process	GO:0006259	227	0.331
nuclear division	GO:0000280	332	0.329
anatomical structure homeostasis	GO:0060249	97	0.311
chromatin mediated maintenance of transcription	GO:0048096	7	0.311
localization of cell	GO:0051674	257	0.310
chromatin assembly	GO:0031497	48	0.303	Human
digestive tract development	GO:0048565	149	0.290
retina development in camera type eye	GO:0060041	4	0.288
epidermis development	GO:0008544	65	0.284
defense response to other organism	GO:0098542	225	0.253
posttranscriptional gene silencing by rna	GO:0035194	45	0.247
protein acylation	GO:0043543	42	0.246	Mouse
appendage morphogenesis	GO:0035107	397	0.244
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.238	Human Mouse
negative regulation of response to stimulus	GO:0048585	258	0.236
response to bacterium	GO:0009617	198	0.233
internal protein amino acid acetylation	GO:0006475	38	0.229	Mouse
neuron projection guidance	GO:0097485	241	0.213
posttranscriptional gene silencing	GO:0016441	46	0.212
endocytosis	GO:0006897	310	0.208
chromosome segregation	GO:0007059	157	0.208
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.193
cell fate specification	GO:0001708	71	0.190
imaginal disc derived appendage development	GO:0048737	399	0.187
regulation of transcription by chromatin organization	GO:0034401	3	0.175
response to other organism	GO:0051707	293	0.174
immune system process	GO:0002376	347	0.173
covalent chromatin modification	GO:0016569	106	0.167	Human Mouse
positive regulation of response to stimulus	GO:0048584	323	0.166
dna replication	GO:0006260	48	0.164
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.164
chemotaxis	GO:0006935	249	0.158
protein modification process	GO:0036211	438	0.156	Human Mouse
negative regulation of chromatin silencing	GO:0031936	9	0.155
positive regulation of chromatin silencing	GO:0031937	16	0.153
dna packaging	GO:0006323	91	0.151	Human
regulation of chromatin modification	GO:1903308	28	0.147	Human Mouse
positive regulation of cellular component organization	GO:0051130	156	0.141
embryonic development via the syncytial blastoderm	GO:0001700	148	0.141
nucleosome mobilization	GO:0042766	9	0.133
appendage development	GO:0048736	401	0.131
dna methylation or demethylation	GO:0044728	4	0.131	Mouse
digestive system development	GO:0055123	149	0.124
histone h4 acetylation	GO:0043967	13	0.123
genital disc development	GO:0035215	44	0.121
positive regulation of developmental process	GO:0051094	143	0.119
regionalization	GO:0003002	416	0.118
wing disc morphogenesis	GO:0007472	344	0.117
regulation of dna metabolic process	GO:0051052	34	0.114
internal peptidyl lysine acetylation	GO:0018393	38	0.114	Mouse
atp dependent chromatin remodeling	GO:0043044	22	0.114
positive regulation of gene expression epigenetic	GO:0045815	16	0.111
embryo development ending in birth or egg hatching	GO:0009792	152	0.109
peptidyl lysine acetylation	GO:0018394	39	0.105	Mouse
gland development	GO:0048732	191	0.100
histone methylation	GO:0016571	40	0.099	Human Mouse
sex differentiation	GO:0007548	81	0.098
histone acetylation	GO:0016573	38	0.097	Mouse
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.097
cellular response to oxygen containing compound	GO:1901701	79	0.097
defense response to bacterium	GO:0042742	178	0.095
meiotic cell cycle	GO:0051321	171	0.094
cell proliferation	GO:0008283	299	0.091
protein localization	GO:0008104	284	0.091
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.087
dna alkylation	GO:0006305	4	0.085	Mouse
imaginal disc derived wing morphogenesis	GO:0007476	337	0.080
skin development	GO:0043588	65	0.080
chromatin assembly or disassembly	GO:0006333	52	0.077	Human
heterochromatin assembly	GO:0031507	13	0.077
peptidyl lysine modification	GO:0018205	57	0.077	Mouse
organelle assembly	GO:0070925	198	0.077
regulation of symbiosis encompassing mutualism through parasitism	GO:0043903	15	0.074
response to endogenous stimulus	GO:0009719	119	0.073
neurological system process	GO:0050877	358	0.073
atp metabolic process	GO:0046034	49	0.072
regulation of multi organism process	GO:0043900	131	0.071
cell migration	GO:0016477	238	0.070
cell motility	GO:0048870	251	0.069
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.068
regulation of cellular component biogenesis	GO:0044087	201	0.068
dna methylation	GO:0006306	4	0.067	Mouse
histone h3 k27 methylation	GO:0070734	6	0.067
regulation of cell fate specification	GO:0042659	27	0.067
negative regulation of cellular component organization	GO:0051129	108	0.067
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.066
meiosis i	GO:0007127	59	0.066
cellular macromolecular complex assembly	GO:0034622	153	0.066
post embryonic appendage morphogenesis	GO:0035120	385	0.065
camera type eye development	GO:0043010	4	0.065
dna templated transcription elongation	GO:0006354	18	0.064
rna interference	GO:0016246	27	0.064
axon development	GO:0061564	297	0.064
salivary gland development	GO:0007431	162	0.063
respiratory system development	GO:0060541	213	0.062
embryonic hindgut morphogenesis	GO:0048619	48	0.062
gastrulation	GO:0007369	70	0.061
epithelial cell differentiation	GO:0030855	322	0.061
defense response	GO:0006952	300	0.060
salivary gland histolysis	GO:0035070	88	0.060
histone h3 k9 acetylation	GO:0043970	3	0.059
regulation of cell cycle process	GO:0010564	181	0.059
production of small rna involved in gene silencing by rna	GO:0070918	15	0.059
regulation of intracellular signal transduction	GO:1902531	236	0.059
cellular amine metabolic process	GO:0044106	12	0.058
regulation of cell cycle	GO:0051726	291	0.058
regulation of cellular amino acid metabolic process	GO:0006521	0	0.057
regulation of dna replication	GO:0006275	13	0.057
ribonucleoprotein complex assembly	GO:0022618	23	0.057
blastoderm segmentation	GO:0007350	159	0.057
regulation of chromatin organization	GO:1902275	32	0.056	Human Mouse
regulation of meiosis	GO:0040020	3	0.056
ribonucleoprotein complex subunit organization	GO:0071826	28	0.055
negative regulation of cell cycle	GO:0045786	116	0.055
regulation of defense response	GO:0031347	102	0.054
regulation of immune system process	GO:0002682	176	0.053
axon guidance	GO:0007411	233	0.052
sister chromatid segregation	GO:0000819	92	0.051
negative regulation of small gtpase mediated signal transduction	GO:0051058	13	0.051
rna processing	GO:0006396	147	0.050
regulation of chromosome organization	GO:0033044	64	0.050	Human Mouse
chromosome condensation	GO:0030261	41	0.049
protein complex biogenesis	GO:0070271	201	0.048
regulation of mrna processing	GO:0050684	71	0.047
vesicle mediated transport	GO:0016192	381	0.047
positive regulation of mrna processing	GO:0050685	4	0.047
response to dsrna	GO:0043331	15	0.046
nucleoside monophosphate catabolic process	GO:0009125	39	0.046
response to oxygen containing compound	GO:1901700	200	0.046
gene silencing by mirna	GO:0035195	22	0.045
regulation of chromatin assembly	GO:0010847	9	0.045
sensory organ morphogenesis	GO:0090596	260	0.044
regulation of protein metabolic process	GO:0051246	256	0.043	Human Mouse
anterior posterior pattern specification	GO:0009952	136	0.043
homeostatic process	GO:0042592	199	0.042
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.042
cellular response to endogenous stimulus	GO:0071495	80	0.042
regulation of mitotic cell cycle	GO:0007346	190	0.041
protein complex assembly	GO:0006461	200	0.041
programmed cell death	GO:0012501	257	0.041
response to organic substance	GO:0010033	284	0.041
organonitrogen compound catabolic process	GO:1901565	128	0.040
exocrine system development	GO:0035272	162	0.039
ubiquitin dependent protein catabolic process	GO:0006511	78	0.039
dsrna fragmentation	GO:0031050	15	0.038
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.038
cellular response to organic substance	GO:0071310	132	0.038
segmentation	GO:0035282	207	0.037
atp catabolic process	GO:0006200	38	0.037
regulation of cell death	GO:0010941	173	0.036
dna dependent dna replication	GO:0006261	17	0.035
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.035
cellular response to chemical stimulus	GO:0070887	199	0.035
organophosphate metabolic process	GO:0019637	195	0.034
negative regulation of signal transduction	GO:0009968	206	0.033
cellular protein modification process	GO:0006464	438	0.032	Human Mouse
dna conformation change	GO:0071103	105	0.032	Human
meiotic chromosome segregation	GO:0045132	59	0.031
regulation of cell proliferation	GO:0042127	163	0.031
regulation of multicellular organismal development	GO:2000026	414	0.031
protein alkylation	GO:0008213	43	0.031	Human Mouse
spindle organization	GO:0007051	253	0.031
defense response to gram negative bacterium	GO:0050829	94	0.030
proteolysis	GO:0006508	192	0.029
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.029
tube morphogenesis	GO:0035239	191	0.029
transcription elongation from rna polymerase ii promoter	GO:0006368	18	0.029
regulation of cell development	GO:0060284	215	0.029
purine ribonucleoside metabolic process	GO:0046128	127	0.029
regulation of mrna metabolic process	GO:1903311	72	0.029
apoptotic signaling pathway	GO:0097190	27	0.028
maternal specification of dorsal ventral axis oocyte germ line encoded	GO:0007311	4	0.028
morphogenesis of an epithelium	GO:0002009	276	0.028
axis specification	GO:0009798	167	0.027
body morphogenesis	GO:0010171	2	0.027
cellular response to dna damage stimulus	GO:0006974	223	0.027
regulation of dna templated transcription elongation	GO:0032784	17	0.027
mitotic cell cycle embryonic	GO:0045448	38	0.027
histone h4 k20 methylation	GO:0034770	4	0.026
nucleoside triphosphate metabolic process	GO:0009141	120	0.026
positive regulation of multicellular organismal process	GO:0051240	143	0.025
cellular response to dsrna	GO:0071359	15	0.025
purine containing compound metabolic process	GO:0072521	155	0.025
regulation of nuclear division	GO:0051783	58	0.025
hindbrain development	GO:0030902	2	0.025
embryonic organ development	GO:0048568	50	0.025
positive regulation of signal transduction	GO:0009967	223	0.024
embryonic axis specification	GO:0000578	107	0.024
histone h3 acetylation	GO:0043966	11	0.024
eye photoreceptor cell differentiation	GO:0001754	145	0.024
mitotic sister chromatid segregation	GO:0000070	87	0.024
cellular macromolecule catabolic process	GO:0044265	136	0.024
positive regulation of cellular component biogenesis	GO:0044089	80	0.023
death	GO:0016265	284	0.023
regulation of cell differentiation	GO:0045595	302	0.023
ribose phosphate metabolic process	GO:0019693	145	0.023
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.023
regulation of phosphatase activity	GO:0010921	3	0.023
regulation of compound eye cone cell fate specification	GO:0042682	4	0.023
regulation of cellular protein metabolic process	GO:0032268	243	0.022	Human Mouse
response to alcohol	GO:0097305	95	0.022
axonogenesis	GO:0007409	290	0.022
regulation of transferase activity	GO:0051338	58	0.022
posttranscriptional regulation of gene expression	GO:0010608	145	0.022
response to temperature stimulus	GO:0009266	106	0.022
negative regulation of developmental process	GO:0051093	201	0.022
response to nitrogen compound	GO:1901698	90	0.021
production of mirnas involved in gene silencing by mirna	GO:0035196	10	0.021
positive regulation of cellular amine metabolic process	GO:0033240	0	0.021
cell division	GO:0051301	248	0.021
positive regulation of cell differentiation	GO:0045597	64	0.021
muscle organ development	GO:0007517	127	0.020
sex determination	GO:0007530	18	0.020
phagocytosis	GO:0006909	215	0.020
regulation of response to dna damage stimulus	GO:2001020	23	0.020
phosphorylation	GO:0016310	294	0.020
regulation of cell fate commitment	GO:0010453	29	0.020
regulation of protein localization to nucleus	GO:1900180	29	0.020
histone exchange	GO:0043486	21	0.020
peptidyl amino acid modification	GO:0018193	105	0.020	Mouse
proteasomal protein catabolic process	GO:0010498	59	0.020
memory	GO:0007613	94	0.020
positive regulation of cell development	GO:0010720	61	0.019
double strand break repair	GO:0006302	26	0.019
regulation of cell division	GO:0051302	72	0.019
regulation of organelle organization	GO:0033043	196	0.019	Human Mouse
response to ionizing radiation	GO:0010212	32	0.019
wnt signaling pathway	GO:0016055	98	0.019
organonitrogen compound metabolic process	GO:1901564	318	0.019
multi organism behavior	GO:0051705	175	0.019
positive regulation of cell cycle process	GO:0090068	28	0.019
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	15	0.019
cellular response to nitrogen compound	GO:1901699	51	0.019
sister chromatid cohesion	GO:0007062	18	0.019
dna recombination	GO:0006310	32	0.019
protein phosphorylation	GO:0006468	169	0.018
macromolecular complex assembly	GO:0065003	256	0.018	Human
salivary gland morphogenesis	GO:0007435	145	0.018
compound eye cone cell fate commitment	GO:0042676	5	0.018
jak stat cascade	GO:0007259	49	0.018
dna repair	GO:0006281	54	0.018
cell cycle checkpoint	GO:0000075	95	0.018
positive regulation of molecular function	GO:0044093	136	0.018
muscle structure development	GO:0061061	224	0.018
negative regulation of signaling	GO:0023057	219	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018
regulation of cellular ketone metabolic process	GO:0010565	3	0.017
positive regulation of cell communication	GO:0010647	250	0.017
histone h4 k12 acetylation	GO:0043983	2	0.017
developmental pigmentation	GO:0048066	68	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.017
regulation of sister chromatid cohesion	GO:0007063	2	0.017
learning or memory	GO:0007611	141	0.017
apoptotic process	GO:0006915	159	0.017
nucleoside monophosphate metabolic process	GO:0009123	52	0.017
positive regulation of cell cycle	GO:0045787	43	0.017
protein maturation	GO:0051604	71	0.017
histone h4 k16 acetylation	GO:0043984	4	0.016
modification dependent protein catabolic process	GO:0019941	78	0.016
regulation of protein import into nucleus	GO:0042306	28	0.016
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.016
hematopoietic or lymphoid organ development	GO:0048534	57	0.016
regeneration	GO:0031099	16	0.016
eye development	GO:0001654	323	0.016
regulation of histone h3 k27 methylation	GO:0061085	3	0.016
cellular catabolic process	GO:0044248	372	0.016
nucleobase containing compound catabolic process	GO:0034655	165	0.016
multicellular organismal reproductive behavior	GO:0033057	110	0.016
immune system development	GO:0002520	57	0.016
hindgut morphogenesis	GO:0007442	58	0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
regulation of rna splicing	GO:0043484	69	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
response to organic cyclic compound	GO:0014070	89	0.015
negative regulation of ras protein signal transduction	GO:0046580	13	0.015
developmental programmed cell death	GO:0010623	138	0.015
regulation of glial cell differentiation	GO:0045685	1	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.014
connective tissue development	GO:0061448	3	0.014
production of sirna involved in rna interference	GO:0030422	11	0.014
regulation of mapk cascade	GO:0043408	92	0.014
dna endoreduplication	GO:0042023	22	0.014
chromosome organization involved in meiosis	GO:0070192	10	0.014
regulation of protein modification process	GO:0031399	112	0.014	Human Mouse
ncrna processing	GO:0034470	30	0.014
receptor mediated endocytosis	GO:0006898	21	0.014
mitotic chromosome condensation	GO:0007076	22	0.014
regulation of apoptotic process	GO:0042981	130	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.014
developmental growth	GO:0048589	280	0.014
regulation of response to stress	GO:0080134	200	0.014
reproductive structure development	GO:0048608	74	0.014
response to hormone	GO:0009725	45	0.013
terminal region determination	GO:0007362	25	0.013
antennal development	GO:0007469	25	0.013
morphogenesis of a branching epithelium	GO:0061138	45	0.013
response to lipopolysaccharide	GO:0032496	4	0.013
photoreceptor cell differentiation	GO:0046530	170	0.013
leg disc development	GO:0035218	92	0.013
eye pigmentation	GO:0048069	43	0.013
positive regulation of multi organism process	GO:0043902	40	0.013
regulation of cell shape	GO:0008360	113	0.013
protein localization to organelle	GO:0033365	82	0.013
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.013
salivary gland cell autophagic cell death	GO:0035071	83	0.013
embryonic pattern specification	GO:0009880	174	0.012
regulation of phosphorylation	GO:0042325	147	0.012
mitotic dna damage checkpoint	GO:0044773	74	0.012
positive regulation of transferase activity	GO:0051347	26	0.012
negative regulation of chromosome organization	GO:2001251	19	0.012
branching morphogenesis of an epithelial tube	GO:0048754	45	0.012
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.012
nucleotide metabolic process	GO:0009117	161	0.012
gland morphogenesis	GO:0022612	145	0.012
positive regulation of immune system process	GO:0002684	68	0.012
regulation of mrna splicing via spliceosome	GO:0048024	64	0.012
negative regulation of immune system process	GO:0002683	50	0.012
meiotic cell cycle process	GO:1903046	132	0.012
nucleosome organization	GO:0034728	59	0.012	Human
negative regulation of sister chromatid segregation	GO:0033046	13	0.012
negative regulation of cardiac cell fate specification	GO:2000044	7	0.011
regulation of phosphate metabolic process	GO:0019220	210	0.011
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.011
mitotic spindle organization	GO:0007052	220	0.011
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.011
regulation of programmed cell death	GO:0043067	152	0.011
reproductive system development	GO:0061458	74	0.011
oocyte dorsal ventral axis specification	GO:0007310	34	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.011
small molecule metabolic process	GO:0044281	305	0.011
regulation of cellular response to stress	GO:0080135	89	0.011
regulation of meiotic cell cycle	GO:0051445	9	0.011
negative regulation of cell communication	GO:0010648	223	0.011
regulation of embryonic development	GO:0045995	68	0.011
regulation of molecular function	GO:0065009	217	0.011	Human
embryonic organ morphogenesis	GO:0048562	5	0.011
cell type specific apoptotic process	GO:0097285	38	0.011
regulation of localization	GO:0032879	275	0.010
eye morphogenesis	GO:0048592	260	0.010
mrna processing	GO:0006397	104	0.010
negative regulation of apoptotic process	GO:0043066	63	0.010
aromatic compound catabolic process	GO:0019439	166	0.010
nucleoside triphosphate catabolic process	GO:0009143	108	0.010
compound eye photoreceptor fate commitment	GO:0001752	36	0.010
hindgut development	GO:0061525	58	0.010
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.010
oxoacid metabolic process	GO:0043436	103	0.010
regulation of gene silencing by mirna	GO:0060964	8	0.010
positive regulation of nervous system development	GO:0051962	69	0.010
purine containing compound catabolic process	GO:0072523	112	0.010
chemosensory behavior	GO:0007635	106	0.010
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010

CTCF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.073
organ system cancer	DOID:0050686	0.073
disease of cellular proliferation	DOID:14566	0.073
disease of anatomical entity	DOID:7	0.013

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