Drosophila melanogaster

19 known processes

Npc2h (Dmel_CG11315)

Niemann-Pick type C-2h

(Aliases: BcDNA:RH04252,BcDNA:RH68460,CG11315,DmML1A,npc2h,BcDNA:GH26608,Dmel\CG11315)

Npc2h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sterol homeostasisGO:005509240.055
Fly
salivary gland developmentGO:00074311620.053
gland developmentGO:00487321910.051
endocytosisGO:00068973100.049
innate immune responseGO:00450871440.045
immune system processGO:00023763470.043
salivary gland cell autophagic cell deathGO:0035071830.043
cell deathGO:00082192790.041
sensory organ morphogenesisGO:00905962600.041
programmed cell deathGO:00125012570.041
developmental programmed cell deathGO:00106231380.040
tissue deathGO:00162711020.039
deathGO:00162652840.036
compound eye developmentGO:00487493070.036
salivary gland morphogenesisGO:00074351450.034
organic substance catabolic processGO:19015753080.033
eye pigment biosynthetic processGO:0006726320.031
lateral inhibitionGO:00463312060.031
histolysisGO:00075591020.031
response to bacteriumGO:00096171980.031
Fly
phagocytosisGO:00069092150.031
imaginal disc derived appendage morphogenesisGO:00351143950.030
gland morphogenesisGO:00226121450.028
salivary gland histolysisGO:0035070880.027
defense response to bacteriumGO:00427421780.027
Fly
compound eye morphogenesisGO:00017452490.025
organic cyclic compound catabolic processGO:19013611680.024
autophagic cell deathGO:0048102830.024
pigmentationGO:0043473750.024
detection of stimulusGO:00516061560.023
eye developmentGO:00016543230.023
exocrine system developmentGO:00352721620.022
cell cell signaling involved in cell fate commitmentGO:00451682100.021
cellular protein modification processGO:00064644380.021
chaeta developmentGO:0022416970.020
protein modification processGO:00362114380.020
vesicle mediated transportGO:00161923810.020
positive regulation of cell communicationGO:00106472500.020
cellular amino acid metabolic processGO:0006520610.020
aromatic compound catabolic processGO:00194391660.020
homeostatic processGO:00425921990.019
Fly
imaginal disc derived appendage developmentGO:00487373990.019
humoral immune responseGO:00069591170.019
defense responseGO:00069523000.019
organic substance transportGO:00717022570.018
Fly
kidney developmentGO:000182230.018
sulfur compound metabolic processGO:0006790590.018
response to woundingGO:0009611940.018
appendage developmentGO:00487364010.018
catabolic processGO:00090564090.018
regulation of localizationGO:00328792750.017
response to abiotic stimulusGO:00096283410.017
post embryonic appendage morphogenesisGO:00351203850.017
regionalizationGO:00030024160.016
negative regulation of cell communicationGO:00106482230.016
cell proliferationGO:00082832990.016
organonitrogen compound metabolic processGO:19015643180.016
regulation of cell cycleGO:00517262910.016
positive regulation of signalingGO:00230562430.015
regulation of transportGO:00510491810.015
response to other organismGO:00517072930.015
Fly
carbohydrate derivative metabolic processGO:19011352170.015
androgen metabolic processGO:000820910.015
enzyme linked receptor protein signaling pathwayGO:00071671790.014
response to oxygen containing compoundGO:19017002000.014
response to lipopolysaccharideGO:003249640.014
oxoacid metabolic processGO:00434361030.014
body morphogenesisGO:001017120.014
positive regulation of signal transductionGO:00099672230.014
negative regulation of biosynthetic processGO:00098902770.014
regulation of molecular functionGO:00650092170.014
phototransductionGO:0007602520.013
dna metabolic processGO:00062592270.013
organelle fissionGO:00482853400.013
cell recognitionGO:00080371020.013
Fly
actin filament organizationGO:00070151260.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
glycerolipid catabolic processGO:004650330.013
pigment metabolic process involved in pigmentationGO:0043474330.012
pigment biosynthetic processGO:0046148360.012
regulation of cell deathGO:00109411730.012
wing disc morphogenesisGO:00074723440.012
negative regulation of signal transductionGO:00099682060.012
organic acid metabolic processGO:00060821030.012
detection of abiotic stimulusGO:0009582660.012
cellular response to chemical stimulusGO:00708871990.012
negative regulation of response to stimulusGO:00485852580.012
negative regulation of signalingGO:00230572190.012
developmental pigmentationGO:0048066680.012
negative regulation of cellular metabolic processGO:00313243820.012
glutathione metabolic processGO:0006749370.011
single organism biosynthetic processGO:00447112060.011
Fly
positive regulation of lipid storageGO:001088440.011
regulation of vesicle mediated transportGO:0060627590.011
nucleobase containing compound catabolic processGO:00346551650.011
lipid metabolic processGO:00066291210.011
Fly
cellular nitrogen compound catabolic processGO:00442701650.011
positive regulation of nitrogen compound metabolic processGO:00511733540.011
positive regulation of cellular biosynthetic processGO:00313283160.011
positive regulation of response to stimulusGO:00485843230.011
carboxylic acid metabolic processGO:0019752920.011
regulation of catabolic processGO:00098941700.011
establishment of localization in cellGO:00516494020.011
positive regulation of macromolecule metabolic processGO:00106044050.011
organophosphate metabolic processGO:00196371950.011
defense response to other organismGO:00985422250.011
Fly
response to nitrogen compoundGO:1901698900.011
response to temperature stimulusGO:00092661060.011
regulation of cell proliferationGO:00421271630.011
organophosphate catabolic processGO:00464341120.011
intracellular signal transductionGO:00355563000.011
nuclear divisionGO:00002803320.011
cellular response to dna damage stimulusGO:00069742230.011
transcription from rna polymerase ii promoterGO:00063663680.011
apoptotic processGO:00069151590.011
regulation of intracellular signal transductionGO:19025312360.011
imaginal disc derived wing morphogenesisGO:00074763370.011
positive regulation of cellular amino acid metabolic processGO:004576400.010
eye morphogenesisGO:00485922600.010
steroid metabolic processGO:0008202200.010
Fly
dorsal ventral axis specificationGO:0009950660.010
response to hexoseGO:000974630.010
single organism catabolic processGO:00447122280.010
positive regulation of catalytic activityGO:00430851180.010
cellular macromolecule catabolic processGO:00442651360.010
cellular modified amino acid metabolic processGO:0006575450.010

Npc2h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012