Drosophila melanogaster

12 known processes

Spn88Eb (Dmel_CG6687)

Serpin 88Eb

(Aliases: CG6687,Dmel\CG6687)

Spn88Eb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to gram positive bacteriumGO:0050830410.228
pattern recognition receptor signaling pathwayGO:000222120.180
response to external biotic stimulusGO:00432072930.176
antibacterial humoral responseGO:0019731440.165
response to biotic stimulusGO:00096072940.128
activation of innate immune responseGO:000221840.120
defense response to other organismGO:00985422250.102
immune system processGO:00023763470.100
defense responseGO:00069523000.100
antimicrobial peptide productionGO:0002775460.100
response to other organismGO:00517072930.085
regulation of immune system processGO:00026821760.084
defense response to bacteriumGO:00427421780.083
response to bacteriumGO:00096171980.078
humoral immune responseGO:00069591170.070
antimicrobial humoral responseGO:0019730990.070
defense response to fungusGO:0050832480.069
organonitrogen compound metabolic processGO:19015643180.068
positive regulation of defense responseGO:0031349590.068
carbohydrate derivative metabolic processGO:19011352170.060
response to lipopolysaccharideGO:003249640.060
defense response to gram negative bacteriumGO:0050829940.057
positive regulation of response to stimulusGO:00485843230.056
innate immune response activating signal transductionGO:000275820.055
positive regulation of immune system processGO:0002684680.055
immune response activating signal transductionGO:000275720.051
immune response regulating signaling pathwayGO:000276420.047
small molecule metabolic processGO:00442813050.046
cellular modified amino acid metabolic processGO:0006575450.045
cell cell signaling involved in cell fate commitmentGO:00451682100.044
organonitrogen compound biosynthetic processGO:19015661170.043
regulation of antimicrobial peptide biosynthetic processGO:0002805380.042
regulation of defense responseGO:00313471020.041
positive regulation of antibacterial peptide productionGO:0002803200.041
glycosyl compound metabolic processGO:19016571270.039
nucleoside metabolic processGO:00091161270.038
regulation of response to stressGO:00801342000.038
immune responseGO:00069552460.037
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0006964120.036
regulation of multi organism processGO:00439001310.036
nucleobase containing small molecule metabolic processGO:00550861740.036
oxoacid metabolic processGO:00434361030.036
organic acid metabolic processGO:00060821030.036
regulation of immune responseGO:00507761180.035
purine containing compound metabolic processGO:00725211550.035
axis specificationGO:00097981670.035
purine nucleoside metabolic processGO:00422781270.035
cellular response to lipopolysaccharideGO:007122230.034
catabolic processGO:00090564090.034
positive regulation of immune responseGO:0050778630.034
dorsal ventral pattern formationGO:00099531330.034
compound eye developmentGO:00487493070.033
lipopolysaccharide mediated signaling pathwayGO:003166310.033
intracellular signal transductionGO:00355563000.032
negative regulation of cell communicationGO:00106482230.031
Fly
regulation of antibacterial peptide productionGO:0002786220.031
cell proliferationGO:00082832990.030
phagocytosisGO:00069092150.030
phosphorylationGO:00163102940.029
peptidoglycan catabolic processGO:000925330.029
organic substance catabolic processGO:19015753080.029
mating behaviorGO:00076171060.029
macromolecule catabolic processGO:00090571610.027
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002813140.027
positive regulation of cellular biosynthetic processGO:00313283160.027
peptidoglycan metabolic processGO:000027030.027
innate immune responseGO:00450871440.027
amide biosynthetic processGO:0043604420.026
positive regulation of biosynthetic processGO:00098913160.025
vesicle mediated transportGO:00161923810.025
regulation of phosphorus metabolic processGO:00511742100.025
glycosaminoglycan catabolic processGO:000602730.025
production of molecular mediator of immune responseGO:0002440460.025
compound eye morphogenesisGO:00017452490.024
regulation of antimicrobial peptide productionGO:0002784440.024
imaginal disc derived appendage developmentGO:00487373990.024
Fly
negative regulation of signalingGO:00230572190.024
Fly
endocytosisGO:00068973100.024
negative regulation of signal transductionGO:00099682060.023
Fly
cellular response to molecule of bacterial originGO:007121930.023
regulation of phosphate metabolic processGO:00192202100.023
antibacterial peptide productionGO:0002778220.023
carboxylic acid metabolic processGO:0019752920.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
cellular response to external stimulusGO:0071496660.023
melanization defense responseGO:0035006450.023
protein modification processGO:00362114380.023
neurological system processGO:00508773580.023
dorsal ventral axis specificationGO:0009950660.023
regulation of innate immune responseGO:0045088710.023
response to fungusGO:0009620500.022
negative regulation of response to stimulusGO:00485852580.022
Fly
cellular response to chemical stimulusGO:00708871990.022
ion transportGO:00068111450.022
sensory organ morphogenesisGO:00905962600.022
cellular protein modification processGO:00064644380.022
carbohydrate derivative catabolic processGO:19011361180.022
eye developmentGO:00016543230.022
biosynthetic process of antibacterial peptides active against gram positive bacteriaGO:000281530.021
appendage morphogenesisGO:00351073970.021
Fly
regulation of cell proliferationGO:00421271630.021
regulation of intracellular signal transductionGO:19025312360.021
response to peptidoglycanGO:003249420.021
positive regulation of antimicrobial humoral responseGO:0002760280.021
regulation of response to external stimulusGO:00321011150.021
secondary metabolic processGO:0019748750.021
negative regulation of cellular metabolic processGO:00313243820.020
regulation of response to biotic stimulusGO:0002831630.020
antimicrobial peptide biosynthetic processGO:0002777380.020
eye morphogenesisGO:00485922600.020
response to oxygen containing compoundGO:19017002000.020
stress activated mapk cascadeGO:0051403520.019
positive regulation of cell motilityGO:200014730.019
regulation of molecular functionGO:00650092170.019
peptide biosynthetic processGO:0043043420.019
regulation of antimicrobial humoral responseGO:0002759500.019
cellular response to extracellular stimulusGO:0031668640.019
regulation of defense response to bacteriumGO:1900424300.019
cellular response to biotic stimulusGO:007121640.018
regulation of humoral immune responseGO:0002920510.018
cellular response to organic substanceGO:00713101320.018
positive regulation of signal transductionGO:00099672230.018
regulation of anatomical structure morphogenesisGO:00226032420.018
wing disc morphogenesisGO:00074723440.018
Fly
antibacterial peptide biosynthetic processGO:0002780220.018
positive regulation of cell migrationGO:003033520.018
organelle fissionGO:00482853400.018
cellular catabolic processGO:00442483720.018
body morphogenesisGO:001017120.018
taxisGO:00423303040.018
positive regulation of production of molecular mediator of immune responseGO:0002702280.018
biosynthetic process of antibacterial peptides active against gram negative bacteriaGO:0002812140.018
appendage developmentGO:00487364010.017
Fly
positive regulation of antibacterial peptide biosynthetic processGO:0006963200.017
lateral inhibitionGO:00463312060.017
positive regulation of humoral immune responseGO:0002922280.017
reproductive behaviorGO:00190981220.017
response to nutrient levelsGO:00316671140.017
regulation of protein metabolic processGO:00512462560.017
cellular amino acid metabolic processGO:0006520610.017
secondary metabolite biosynthetic processGO:0044550240.017
deathGO:00162652840.017
immune effector processGO:0002252980.017
cellular response to starvationGO:0009267610.017
imaginal disc derived wing morphogenesisGO:00074763370.017
Fly
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of cell communicationGO:00106472500.016
negative regulation of gene expressionGO:00106293870.016
positive regulation of signalingGO:00230562430.016
cation transportGO:00068121100.016
proteolysisGO:00065081920.016
multicellular organismal reproductive behaviorGO:00330571100.016
cellular ketone metabolic processGO:0042180240.016
regulation of production of molecular mediator of immune responseGO:0002700440.016
regulation of cellular protein metabolic processGO:00322682430.015
gene silencingGO:00164581380.015
response to organic substanceGO:00100332840.015
homeostatic processGO:00425921990.015
extracellular structure organizationGO:0043062460.015
spindle organizationGO:00070512530.015
cell deathGO:00082192790.015
jnk cascadeGO:0007254500.015
regulation of multicellular organismal developmentGO:20000264140.015
mitotic nuclear divisionGO:00070672130.015
single organism biosynthetic processGO:00447112060.015
regulation of cellular response to stressGO:0080135890.015
positive regulation of multi organism processGO:0043902400.015
regulation of antibacterial peptide biosynthetic processGO:0002808220.015
regionalizationGO:00030024160.015
cellular amide metabolic processGO:0043603800.015
positive regulation of innate immune responseGO:0045089380.015
negative regulation of developmental processGO:00510932010.014
regulation of catalytic activityGO:00507901850.014
protein phosphorylationGO:00064681690.014
regulation of cell cycleGO:00517262910.014
establishment of localization in cellGO:00516494020.014
regulation of cellular amide metabolic processGO:0034248390.014
post embryonic appendage morphogenesisGO:00351203850.014
Fly
regulation of cellular ketone metabolic processGO:001056530.014
negative regulation of peptidoglycan recognition protein signaling pathwayGO:006106030.014
chemotaxisGO:00069352490.014
response to abiotic stimulusGO:00096283410.014
positive regulation of melanization defense responseGO:003500810.014
matingGO:00076181200.014
nuclear divisionGO:00002803320.014
single organism catabolic processGO:00447122280.014
response to organophosphorusGO:004668320.014
axon developmentGO:00615642970.013
organic substance transportGO:00717022570.013
melanin metabolic processGO:0006582470.013
response to organonitrogen compoundGO:0010243750.013
positive regulation of antimicrobial peptide productionGO:0002225280.013
neuropeptide signaling pathwayGO:0007218450.013
regulation of phosphorylationGO:00423251470.013
cellular response to oxygen containing compoundGO:1901701790.013
developmental maturationGO:00217001720.013
positive regulation of defense response to bacteriumGO:1900426230.013
very long chain fatty acid metabolic processGO:000003840.013
regulation of mapk cascadeGO:0043408920.013
amino sugar catabolic processGO:004634830.013
chemical homeostasisGO:0048878920.013
response to glucoseGO:000974920.013
negative regulation of cellular protein metabolic processGO:0032269850.013
positive regulation of phosphorus metabolic processGO:00105621390.013
mapk cascadeGO:00001651070.013
protein maturationGO:0051604710.013
cellular response to nutrient levelsGO:0031669620.013
intracellular transportGO:00469072280.012
gene silencing by rnaGO:0031047570.012
antifungal humoral responseGO:0019732120.012
ribonucleoside metabolic processGO:00091191270.012
cellular nitrogen compound catabolic processGO:00442701650.012
ras protein signal transductionGO:0007265880.012
regulation of cell morphogenesisGO:00226041630.012
meiotic cell cycleGO:00513211710.012
segmentationGO:00352822070.012
alpha amino acid metabolic processGO:1901605200.012
mitotic spindle organizationGO:00070522200.012
signal transduction by phosphorylationGO:00230141070.012
genital disc developmentGO:0035215440.012
negative regulation of protein metabolic processGO:0051248850.012
toll signaling pathwayGO:0008063250.012
Fly
negative regulation of cell differentiationGO:00455961430.012
cell maturationGO:00484691440.012
amine metabolic processGO:0009308120.012
macromolecular complex assemblyGO:00650032560.012
tripartite regional subdivisionGO:00073511030.012
transcription from rna polymerase ii promoterGO:00063663680.012
positive regulation of cellular amide metabolic processGO:0034250260.012
forebrain developmentGO:003090020.012
peptide metabolic processGO:0006518800.012
programmed cell deathGO:00125012570.012
imaginal disc derived appendage morphogenesisGO:00351143950.012
Fly
camera type eye developmentGO:004301040.012
regulation of cellular amine metabolic processGO:003323830.012
regulation of localizationGO:00328792750.012
chromosome segregationGO:00070591570.012
pigment metabolic processGO:0042440840.011
connective tissue developmentGO:006144830.011
stress activated protein kinase signaling cascadeGO:0031098550.011
positive regulation of macromolecule metabolic processGO:00106044050.011
autophagic cell deathGO:0048102830.011
ovarian follicle cell developmentGO:00307072480.011
regulation of cell substrate adhesionGO:001081020.011
actin filament based processGO:00300292200.011
blastoderm segmentationGO:00073501590.011
neuron projection guidanceGO:00974852410.011
biological adhesionGO:00226101380.011
small gtpase mediated signal transductionGO:0007264880.011
axonogenesisGO:00074092900.011
wound healingGO:0042060750.011
positive regulation of phosphate metabolic processGO:00459371390.011
cell adhesionGO:00071551360.011
regulation of cell differentiationGO:00455953020.011
purine ribonucleoside metabolic processGO:00461281270.011
kidney developmentGO:000182230.011
positive regulation of catalytic activityGO:00430851180.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
cellular amine metabolic processGO:0044106120.011
cellular macromolecule catabolic processGO:00442651360.011
aromatic compound catabolic processGO:00194391660.011
cellular macromolecule localizationGO:00707272200.011
localization of cellGO:00516742570.011
g protein coupled receptor signaling pathwayGO:00071861360.011
negative regulation of phosphorylationGO:0042326350.011
posttranscriptional regulation of gene expressionGO:00106081450.011
protein heterooligomerizationGO:005129140.010
single organism cell adhesionGO:0098602470.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
regulation of peptidoglycan recognition protein signaling pathwayGO:006105840.010
positive regulation of hemocyte proliferationGO:003520840.010
oocyte constructionGO:00073081120.010
regulation of cell deathGO:00109411730.010
response to monosaccharideGO:003428440.010
developmental growthGO:00485892800.010
Fly
regulation of cell developmentGO:00602842150.010
developmental programmed cell deathGO:00106231380.010
regulation of nervous system developmentGO:00519602480.010
organophosphate metabolic processGO:00196371950.010
regulation of cell cycle processGO:00105641810.010
negative regulation of immune system processGO:0002683500.010
axon guidanceGO:00074112330.010
cell migrationGO:00164772380.010
peptidoglycan recognition protein signaling pathwayGO:0061057160.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010
positive regulation of gene expressionGO:00106282900.010
long chain fatty acid metabolic processGO:000167630.010
xenobiotic catabolic processGO:004217810.010
organic hydroxy compound metabolic processGO:1901615830.010

Spn88Eb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.014
cardiovascular system diseaseDOID:128700.011