IMP: Integrative Multi-species Prediction

Drosophila melanogaster

138 known processes

CG7158 (Dmel_CG7158)

CG7158 gene product from transcript CG7158-RA

(Aliases: Dmel\CG7158)

FLYBASE: FBgn0037116
Entrez: 40410
UniProtKB: Q9VNZ8

Process Predictions
Disease Predictions

CG7158 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of phosphate metabolic process	GO:0019220	210	0.355
regulation of molecular function	GO:0065009	217	0.346
regulation of phosphorus metabolic process	GO:0051174	210	0.221
positive regulation of gtpase activity	GO:0043547	43	0.218
actin filament based process	GO:0030029	220	0.206
glycerolipid metabolic process	GO:0046486	34	0.197
protein modification by small protein conjugation or removal	GO:0070647	106	0.196
positive regulation of nucleoside metabolic process	GO:0045979	47	0.185
phosphorylation	GO:0016310	294	0.178	Human
ribonucleoside metabolic process	GO:0009119	127	0.174
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.171
vesicle mediated transport	GO:0016192	381	0.165
protein complex biogenesis	GO:0070271	201	0.163
lipid modification	GO:0030258	24	0.162
guanosine containing compound metabolic process	GO:1901068	74	0.161
small molecule metabolic process	GO:0044281	305	0.158
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.154
cellular protein modification process	GO:0006464	438	0.153	Human
intracellular signal transduction	GO:0035556	300	0.147
nucleoside triphosphate catabolic process	GO:0009143	108	0.147
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.144
actin cytoskeleton organization	GO:0030036	206	0.141
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.139
regulation of cell cycle	GO:0051726	291	0.138
purine nucleoside metabolic process	GO:0042278	127	0.136
male gamete generation	GO:0048232	201	0.133
positive regulation of ras gtpase activity	GO:0032320	36	0.133
protein modification process	GO:0036211	438	0.129	Human
glycosyl compound metabolic process	GO:1901657	127	0.127
heterocycle catabolic process	GO:0046700	166	0.123
cell motility	GO:0048870	251	0.115
organic substance catabolic process	GO:1901575	308	0.113
negative regulation of cellular metabolic process	GO:0031324	382	0.112
purine nucleotide catabolic process	GO:0006195	109	0.112
positive regulation of molecular function	GO:0044093	136	0.110
regulation of catalytic activity	GO:0050790	185	0.109
ras protein signal transduction	GO:0007265	88	0.109
purine nucleotide metabolic process	GO:0006163	146	0.108
nucleobase containing small molecule metabolic process	GO:0055086	174	0.107
organelle assembly	GO:0070925	198	0.104
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.103
regulation of purine nucleotide catabolic process	GO:0033121	48	0.101
nucleoside phosphate catabolic process	GO:1901292	110	0.094
cellular lipid metabolic process	GO:0044255	83	0.093
regulation of cell cycle process	GO:0010564	181	0.092
protein complex assembly	GO:0006461	200	0.091
cellular catabolic process	GO:0044248	372	0.088
establishment of localization in cell	GO:0051649	402	0.087
carbohydrate derivative catabolic process	GO:1901136	118	0.086
nucleobase containing compound catabolic process	GO:0034655	165	0.085
lipid metabolic process	GO:0006629	121	0.085
purine containing compound metabolic process	GO:0072521	155	0.084
purine ribonucleoside metabolic process	GO:0046128	127	0.081
immune response	GO:0006955	246	0.079
organophosphate catabolic process	GO:0046434	112	0.078
regulation of anatomical structure morphogenesis	GO:0022603	242	0.074
regulation of gtp catabolic process	GO:0033124	44	0.072
ribose phosphate metabolic process	GO:0019693	145	0.071
gtp metabolic process	GO:0046039	72	0.071
organonitrogen compound metabolic process	GO:1901564	318	0.069
regulation of cell development	GO:0060284	215	0.069
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.069
guanosine containing compound catabolic process	GO:1901069	74	0.068
regulation of organelle organization	GO:0033043	196	0.067
purine ribonucleotide metabolic process	GO:0009150	145	0.066
positive regulation of phosphate metabolic process	GO:0045937	139	0.065
endoplasmic reticulum organization	GO:0007029	13	0.064
regulation of cellular catabolic process	GO:0031329	157	0.064
positive regulation of gtp catabolic process	GO:0033126	43	0.064
ribonucleotide metabolic process	GO:0009259	145	0.064
positive regulation of cellular catabolic process	GO:0031331	95	0.062
positive regulation of nucleotide metabolic process	GO:0045981	55	0.061
regulation of cellular component biogenesis	GO:0044087	201	0.061
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.061
regulation of catabolic process	GO:0009894	170	0.060
purine nucleoside catabolic process	GO:0006152	112	0.060
cell death	GO:0008219	279	0.060
positive regulation of catabolic process	GO:0009896	105	0.060
organelle fission	GO:0048285	340	0.059
small gtpase mediated signal transduction	GO:0007264	88	0.058
regulation of nucleotide catabolic process	GO:0030811	48	0.058
sensory organ morphogenesis	GO:0090596	260	0.057
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.056
molting cycle chitin based cuticle	GO:0007591	56	0.056
positive regulation of hydrolase activity	GO:0051345	78	0.055
ameboidal type cell migration	GO:0001667	151	0.055
glycerophospholipid metabolic process	GO:0006650	23	0.054
ribonucleotide catabolic process	GO:0009261	109	0.053
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.053
ribonucleoside catabolic process	GO:0042454	112	0.052
positive regulation of catalytic activity	GO:0043085	118	0.052
sterol homeostasis	GO:0055092	4	0.051
regulation of ras gtpase activity	GO:0032318	38	0.051
negative regulation of cellular biosynthetic process	GO:0031327	277	0.051
regulation of hydrolase activity	GO:0051336	97	0.051
endosomal transport	GO:0016197	44	0.050
nucleoside triphosphate metabolic process	GO:0009141	120	0.050
regulation of intracellular signal transduction	GO:1902531	236	0.049
endomembrane system organization	GO:0010256	119	0.049	Human
nuclear division	GO:0000280	332	0.049
stem cell maintenance	GO:0019827	67	0.049
regulation of protein metabolic process	GO:0051246	256	0.048	Human
regulation of vesicle mediated transport	GO:0060627	59	0.048
regulation of phosphorylation	GO:0042325	147	0.048	Human
positive regulation of nucleotide catabolic process	GO:0030813	46	0.047
positive regulation of protein metabolic process	GO:0051247	128	0.047	Human
cell division	GO:0051301	248	0.047
regulation of protein kinase activity	GO:0045859	51	0.047	Human
cellular protein complex assembly	GO:0043623	71	0.046
carbohydrate derivative metabolic process	GO:1901135	217	0.046
cellular component assembly involved in morphogenesis	GO:0010927	151	0.046
nucleotide metabolic process	GO:0009117	161	0.045
organonitrogen compound catabolic process	GO:1901565	128	0.045
mitotic nuclear division	GO:0007067	213	0.045
regulation of localization	GO:0032879	275	0.044
catabolic process	GO:0009056	409	0.044
organophosphate metabolic process	GO:0019637	195	0.044
death	GO:0016265	284	0.043
localization of cell	GO:0051674	257	0.043
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.043
protein phosphorylation	GO:0006468	169	0.042	Human
cell projection assembly	GO:0030031	94	0.042
regulation of ras protein signal transduction	GO:0046578	93	0.041
spermatogenesis	GO:0007283	200	0.041
multi multicellular organism process	GO:0044706	123	0.040
golgi organization	GO:0007030	66	0.040
organic substance transport	GO:0071702	257	0.040
nucleoside phosphate metabolic process	GO:0006753	162	0.040
positive regulation of cellular component organization	GO:0051130	156	0.040
single organism catabolic process	GO:0044712	228	0.039
single organism intracellular transport	GO:1902582	207	0.039
positive regulation of exocytosis	GO:0045921	4	0.039
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.038
purine containing compound catabolic process	GO:0072523	112	0.038
regulation of programmed cell death	GO:0043067	152	0.038
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.038
stem cell differentiation	GO:0048863	117	0.037
regulation of cytoskeleton organization	GO:0051493	89	0.037
response to hydrogen peroxide	GO:0042542	11	0.037
negative regulation of mitotic cell cycle	GO:0045930	109	0.036
regulation of immune effector process	GO:0002697	52	0.036
negative regulation of cell communication	GO:0010648	223	0.036
regulation of gtpase activity	GO:0043087	44	0.035
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.035
cellular nitrogen compound catabolic process	GO:0044270	165	0.035
tissue death	GO:0016271	102	0.035
developmental growth	GO:0048589	280	0.035
epithelial cell differentiation	GO:0030855	322	0.034
maintenance of location	GO:0051235	73	0.034
secretion	GO:0046903	109	0.034
homeostatic process	GO:0042592	199	0.034
glycosyl compound catabolic process	GO:1901658	112	0.033
cellular response to oxygen containing compound	GO:1901701	79	0.033
actin filament polymerization	GO:0030041	27	0.031
response to organonitrogen compound	GO:0010243	75	0.031
oocyte differentiation	GO:0009994	145	0.031
organic cyclic compound catabolic process	GO:1901361	168	0.031
regulation of cell differentiation	GO:0045595	302	0.031
positive regulation of phosphorus metabolic process	GO:0010562	139	0.030
cell migration	GO:0016477	238	0.030
response to heat	GO:0009408	63	0.030
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.029
rho protein signal transduction	GO:0007266	14	0.028
epithelium migration	GO:0090132	148	0.028
axonogenesis	GO:0007409	290	0.028
regulation of multi organism process	GO:0043900	131	0.028
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.028
response to hormone	GO:0009725	45	0.028
hindbrain development	GO:0030902	2	0.027
regulation of protein modification process	GO:0031399	112	0.027	Human
humoral immune response	GO:0006959	117	0.027
negative regulation of signal transduction	GO:0009968	206	0.027
positive regulation of rho gtpase activity	GO:0032321	19	0.027	Human
intracellular transport	GO:0046907	228	0.027
cellular response to insulin stimulus	GO:0032869	28	0.026
regulation of cell division	GO:0051302	72	0.026
positive regulation of cell communication	GO:0010647	250	0.026
regulation of multicellular organismal development	GO:2000026	414	0.026
response to organic substance	GO:0010033	284	0.025
negative regulation of signaling	GO:0023057	219	0.025
immune system process	GO:0002376	347	0.025
cellular macromolecule catabolic process	GO:0044265	136	0.025
single organism behavior	GO:0044708	391	0.025
macromolecule catabolic process	GO:0009057	161	0.025
developmental programmed cell death	GO:0010623	138	0.025
actin filament organization	GO:0007015	126	0.025
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.024
protein polymerization	GO:0051258	42	0.024
regulation of protein phosphorylation	GO:0001932	64	0.024	Human
regulation of nucleotide metabolic process	GO:0006140	62	0.024
immune effector process	GO:0002252	98	0.024
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.024
stem cell development	GO:0048864	79	0.024
endocytosis	GO:0006897	310	0.024
negative regulation of molecular function	GO:0044092	51	0.023
modification dependent protein catabolic process	GO:0019941	78	0.023
embryo development ending in birth or egg hatching	GO:0009792	152	0.023
regulation of multicellular organism growth	GO:0040014	40	0.022
regulation of cellular protein metabolic process	GO:0032268	243	0.022	Human
negative regulation of response to stimulus	GO:0048585	258	0.022
nucleoside metabolic process	GO:0009116	127	0.022
regulation of cytokinesis	GO:0032465	3	0.022
nitrogen compound transport	GO:0071705	85	0.022
positive regulation of response to stimulus	GO:0048584	323	0.022
programmed cell death	GO:0012501	257	0.022
dna templated transcription elongation	GO:0006354	18	0.022
regulation of cellular ketone metabolic process	GO:0010565	3	0.021
actomyosin structure organization	GO:0031032	56	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
compound eye morphogenesis	GO:0001745	249	0.020
spindle organization	GO:0007051	253	0.020
gland development	GO:0048732	191	0.020
cellular response to organonitrogen compound	GO:0071417	36	0.020
vesicle organization	GO:0016050	44	0.020
response to monosaccharide	GO:0034284	4	0.020
regulation of cell shape	GO:0008360	113	0.020
regulation of transport	GO:0051049	181	0.020
embryonic morphogenesis	GO:0048598	206	0.020
cell fate determination	GO:0001709	91	0.019
dephosphorylation	GO:0016311	51	0.019
nucleoside catabolic process	GO:0009164	112	0.019
regulation of transferase activity	GO:0051338	58	0.019	Human
negative regulation of cell differentiation	GO:0045596	143	0.019
regulation of cell cycle phase transition	GO:1901987	130	0.019
regulation of hemocyte proliferation	GO:0035206	37	0.019
eye morphogenesis	GO:0048592	260	0.019
response to oxygen containing compound	GO:1901700	200	0.019
gtp catabolic process	GO:0006184	72	0.019
positive regulation of rab gtpase activity	GO:0032851	7	0.019
purine ribonucleotide catabolic process	GO:0009154	109	0.019
negative regulation of gene expression	GO:0010629	387	0.019
brain development	GO:0007420	120	0.019
negative regulation of cytoskeleton organization	GO:0051494	30	0.018
eye development	GO:0001654	323	0.018
positive regulation of cellular biosynthetic process	GO:0031328	316	0.018
organonitrogen compound biosynthetic process	GO:1901566	117	0.018
autophagic cell death	GO:0048102	83	0.018
regulation of cell adhesion	GO:0030155	27	0.018
axis specification	GO:0009798	167	0.018
single organism biosynthetic process	GO:0044711	206	0.018
regulation of nucleoside metabolic process	GO:0009118	50	0.018
post golgi vesicle mediated transport	GO:0006892	11	0.018
nucleotide catabolic process	GO:0009166	109	0.018
regulation of actin cytoskeleton organization	GO:0032956	42	0.018
protein ubiquitination	GO:0016567	70	0.018
taxis	GO:0042330	304	0.017
proteolysis	GO:0006508	192	0.017
innate immune response	GO:0045087	144	0.017
response to wounding	GO:0009611	94	0.017
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.017
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
regulation of cell morphogenesis	GO:0022604	163	0.017
wing disc morphogenesis	GO:0007472	344	0.016
positive regulation of signaling	GO:0023056	243	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
establishment or maintenance of cell polarity	GO:0007163	167	0.016
membrane organization	GO:0061024	112	0.016
cell growth	GO:0016049	108	0.016
regulation of rho gtpase activity	GO:0032319	20	0.016	Human
cellular response to chemical stimulus	GO:0070887	199	0.016
histolysis	GO:0007559	102	0.016
single organism cellular localization	GO:1902580	180	0.016
regulation of purine nucleotide metabolic process	GO:1900542	62	0.016
positive regulation of cellular protein metabolic process	GO:0032270	118	0.016	Human
neurological system process	GO:0050877	358	0.016
cellular ketone metabolic process	GO:0042180	24	0.016
regulation of protein complex assembly	GO:0043254	42	0.016
phospholipid metabolic process	GO:0006644	23	0.015
mitotic spindle organization	GO:0007052	220	0.015
cellular response to peptide hormone stimulus	GO:0071375	28	0.015
single organism membrane budding	GO:1902591	2	0.015
regulation of secretion	GO:0051046	44	0.015
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.015
regulation of cellular amine metabolic process	GO:0033238	3	0.015
telencephalon development	GO:0021537	2	0.015
oocyte development	GO:0048599	124	0.015
lateral inhibition	GO:0046331	206	0.015
tissue morphogenesis	GO:0048729	297	0.015
exocytosis	GO:0006887	28	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.015
negative regulation of developmental process	GO:0051093	201	0.015
lipid homeostasis	GO:0055088	33	0.015
cell recognition	GO:0008037	102	0.015
protein catabolic process	GO:0030163	101	0.015
anion homeostasis	GO:0055081	3	0.015
positive regulation of cell motility	GO:2000147	3	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
positive regulation of cell migration	GO:0030335	2	0.015
protein modification by small protein conjugation	GO:0032446	79	0.014
regulation of immune system process	GO:0002682	176	0.014
response to peptide	GO:1901652	29	0.014
cholesterol homeostasis	GO:0042632	3	0.014
appendage morphogenesis	GO:0035107	397	0.014
cell proliferation	GO:0008283	299	0.014
salivary gland histolysis	GO:0035070	88	0.014
open tracheal system development	GO:0007424	204	0.014
cellular macromolecule localization	GO:0070727	220	0.014
negative regulation of phosphorus metabolic process	GO:0010563	45	0.014
secretion by cell	GO:0032940	101	0.014
positive regulation of autophagy	GO:0010508	21	0.013
cellular amine metabolic process	GO:0044106	12	0.013
rna localization	GO:0006403	115	0.013
positive regulation of signal transduction	GO:0009967	223	0.013
axon guidance	GO:0007411	233	0.013
response to peptide hormone	GO:0043434	29	0.013
negative regulation of transcription dna templated	GO:0045892	237	0.013
regulation of protein localization	GO:0032880	76	0.013
anatomical structure homeostasis	GO:0060249	97	0.013
response to starvation	GO:0042594	97	0.013
dorsal ventral pattern formation	GO:0009953	133	0.013
epithelial cell migration	GO:0010631	148	0.013
macromolecular complex assembly	GO:0065003	256	0.013
oxoacid metabolic process	GO:0043436	103	0.013
peptide biosynthetic process	GO:0043043	42	0.013
proteasomal protein catabolic process	GO:0010498	59	0.013
protein modification by small protein removal	GO:0070646	28	0.013
negative regulation of phosphorylation	GO:0042326	35	0.013
response to endogenous stimulus	GO:0009719	119	0.013
forebrain development	GO:0030900	2	0.013
positive regulation of organelle organization	GO:0010638	65	0.013
epithelial cell development	GO:0002064	274	0.013
insulin receptor signaling pathway	GO:0008286	25	0.013
purine ribonucleoside catabolic process	GO:0046130	112	0.013
plasma membrane organization	GO:0007009	26	0.013
wound healing	GO:0042060	75	0.013
regulation of cell death	GO:0010941	173	0.012
axon development	GO:0061564	297	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
camera type eye development	GO:0043010	4	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
positive regulation of cell differentiation	GO:0045597	64	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.012
golgi vesicle transport	GO:0048193	27	0.012
regulation of apoptotic process	GO:0042981	130	0.012
positive regulation of mitochondrion organization	GO:0010822	8	0.012
growth	GO:0040007	359	0.012
cilium morphogenesis	GO:0060271	39	0.012
positive regulation of cellular component biogenesis	GO:0044089	80	0.012
multicellular organismal reproductive behavior	GO:0033057	110	0.012
body morphogenesis	GO:0010171	2	0.012
positive regulation of multicellular organismal process	GO:0051240	143	0.012
autophagy	GO:0006914	108	0.011
chemotaxis	GO:0006935	249	0.011
biological adhesion	GO:0022610	138	0.011
imaginal disc derived wing morphogenesis	GO:0007476	337	0.011
compound eye development	GO:0048749	307	0.011
columnar cuboidal epithelial cell development	GO:0002066	249	0.011
regulation of nervous system development	GO:0051960	248	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.011
negative regulation of cell development	GO:0010721	62	0.011
oocyte construction	GO:0007308	112	0.011
salivary gland development	GO:0007431	162	0.011
cellular response to peptide	GO:1901653	28	0.011
neuron projection guidance	GO:0097485	241	0.011
retrograde transport endosome to golgi	GO:0042147	3	0.011
molting cycle	GO:0042303	56	0.011
response to extracellular stimulus	GO:0009991	116	0.011
regulation of neurogenesis	GO:0050767	158	0.011
eye photoreceptor cell differentiation	GO:0001754	145	0.011
cell adhesion	GO:0007155	136	0.011
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.011
positive regulation of phosphorylation	GO:0042327	87	0.011	Human
leg disc development	GO:0035218	92	0.011
regulation of locomotion	GO:0040012	42	0.011
mapk cascade	GO:0000165	107	0.011
response to abiotic stimulus	GO:0009628	341	0.011
positive regulation of developmental growth	GO:0048639	62	0.010
lipid localization	GO:0010876	54	0.010
regulation of notch signaling pathway	GO:0008593	100	0.010
response to inorganic substance	GO:0010035	44	0.010
phagocytosis	GO:0006909	215	0.010
regulation of rab gtpase activity	GO:0032313	7	0.010
ovarian follicle cell development	GO:0030707	248	0.010
maintenance of location in cell	GO:0051651	28	0.010
chemical homeostasis	GO:0048878	92	0.010
tissue migration	GO:0090130	155	0.010
signal transduction by phosphorylation	GO:0023014	107	0.010
regulation of humoral immune response	GO:0002920	51	0.010
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010

CG7158 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.090	Human
nervous system disease	DOID:863	0.084	Human
central nervous system disease	DOID:331	0.019	Human

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