Drosophila melanogaster

39 known processes

Sk2 (Dmel_CG32484)

Sphingosine kinase 2

(Aliases: Dmel\CG32484,Sphk2,CG32484,CG2159,SK2)

Sk2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein modification processGO:00362114380.380
regulation of phosphorus metabolic processGO:00511742100.283
cellular protein modification processGO:00064644380.229
locomotory behaviorGO:00076261760.199
intracellular signal transductionGO:00355563000.189
epithelial cell differentiationGO:00308553220.184
positive regulation of cell communicationGO:00106472500.163
Worm
sensory organ morphogenesisGO:00905962600.149
regulation of nervous system developmentGO:00519602480.113
organophosphate metabolic processGO:00196371950.112
organonitrogen compound metabolic processGO:19015643180.106
positive regulation of signalingGO:00230562430.101
Worm
positive regulation of response to stimulusGO:00485843230.098
central nervous system developmentGO:00074172010.082
Mouse
phosphorylationGO:00163102940.082
positive regulation of phosphate metabolic processGO:00459371390.079
appendage morphogenesisGO:00351073970.079
compound eye morphogenesisGO:00017452490.075
negative regulation of cellular metabolic processGO:00313243820.074
cellular lipid metabolic processGO:0044255830.072
small molecule metabolic processGO:00442813050.069
Mouse
oxoacid metabolic processGO:00434361030.069
wing disc morphogenesisGO:00074723440.067
brain developmentGO:00074201200.065
Mouse
establishment of localization in cellGO:00516494020.064
Worm
positive regulation of phosphorus metabolic processGO:00105621390.062
transcription from rna polymerase ii promoterGO:00063663680.062
organonitrogen compound biosynthetic processGO:19015661170.061
carboxylic acid metabolic processGO:0019752920.060
regulation of catabolic processGO:00098941700.059
endocytosisGO:00068973100.057
negative regulation of response to stimulusGO:00485852580.057
chromatin modificationGO:00165681470.057
lipid metabolic processGO:00066291210.055
cognitionGO:00508901410.055
regulation of protein metabolic processGO:00512462560.055
compound eye developmentGO:00487493070.055
morphogenesis of an epitheliumGO:00020092760.054
post embryonic appendage morphogenesisGO:00351203850.054
negative regulation of signal transductionGO:00099682060.053
regulation of cell differentiationGO:00455953020.053
cellular catabolic processGO:00442483720.052
ribose phosphate metabolic processGO:00196931450.050
stem cell differentiationGO:00488631170.049
regulation of intracellular signal transductionGO:19025312360.049
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.047
regulation of multicellular organismal developmentGO:20000264140.046
negative regulation of multicellular organismal processGO:00512411420.046
imaginal disc derived appendage developmentGO:00487373990.046
single organism catabolic processGO:00447122280.045
imaginal disc derived wing morphogenesisGO:00074763370.045
carbohydrate derivative metabolic processGO:19011352170.043
imaginal disc derived appendage morphogenesisGO:00351143950.043
telencephalon developmentGO:002153720.043
adult locomotory behaviorGO:0008344760.043
positive regulation of nucleobase containing compound metabolic processGO:00459353320.043
appendage developmentGO:00487364010.042
positive regulation of macromolecule metabolic processGO:00106044050.042
ras protein signal transductionGO:0007265880.041
single organism biosynthetic processGO:00447112060.041
protein phosphorylationGO:00064681690.040
nucleoside triphosphate catabolic processGO:00091431080.039
organic acid metabolic processGO:00060821030.039
enzyme linked receptor protein signaling pathwayGO:00071671790.037
positive regulation of nitrogen compound metabolic processGO:00511733540.036
positive regulation of biosynthetic processGO:00098913160.036
purine nucleotide metabolic processGO:00061631460.035
erbb signaling pathwayGO:0038127580.035
regulation of phosphate metabolic processGO:00192202100.035
cellular amine metabolic processGO:0044106120.034
intracellular transportGO:00469072280.033
single organism behaviorGO:00447083910.033
purine nucleoside triphosphate metabolic processGO:00091441190.033
nucleoside phosphate metabolic processGO:00067531620.033
response to nutrient levelsGO:00316671140.033
positive regulation of signal transductionGO:00099672230.032
eye developmentGO:00016543230.032
forebrain developmentGO:003090020.032
amine metabolic processGO:0009308120.032
response to organic substanceGO:00100332840.032
nucleobase containing compound catabolic processGO:00346551650.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
positive regulation of cellular biosynthetic processGO:00313283160.030
protein localizationGO:00081042840.030
organic substance transportGO:00717022570.030
Worm
nucleotide metabolic processGO:00091171610.030
cell motilityGO:00488702510.029
regulation of small gtpase mediated signal transductionGO:0051056930.029
epidermal growth factor receptor signaling pathwayGO:0007173580.029
establishment or maintenance of cell polarityGO:00071631670.029
guanosine containing compound metabolic processGO:1901068740.028
cellular amino acid metabolic processGO:0006520610.028
positive regulation of intracellular signal transductionGO:19025331160.028
cell proliferationGO:00082832990.028
Mouse
spermatogenesisGO:00072832000.028
germarium derived egg chamber formationGO:00072931010.027
autophagyGO:00069141080.027
small gtpase mediated signal transductionGO:0007264880.027
ion transportGO:00068111450.027
Worm
positive regulation of phosphorylationGO:0042327870.026
nucleobase containing small molecule metabolic processGO:00550861740.026
deathGO:00162652840.026
localization of cellGO:00516742570.026
cell deathGO:00082192790.025
cellular response to starvationGO:0009267610.025
peptidyl amino acid modificationGO:00181931050.025
positive regulation of developmental processGO:00510941430.025
axonogenesisGO:00074092900.025
positive regulation of multicellular organismal processGO:00512401430.024
cell migrationGO:00164772380.024
axon developmentGO:00615642970.024
regulation of cellular catabolic processGO:00313291570.024
purine ribonucleotide metabolic processGO:00091501450.024
regulation of cellular ketone metabolic processGO:001056530.024
mapk cascadeGO:00001651070.024
regulation of ras protein signal transductionGO:0046578930.024
regulation of phosphorylationGO:00423251470.024
regulation of autophagyGO:0010506620.023
positive regulation of rna metabolic processGO:00512542710.023
response to extracellular stimulusGO:00099911160.023
glycosyl compound catabolic processGO:19016581120.023
adult behaviorGO:00305341370.023
response to starvationGO:0042594970.023
response to oxygen containing compoundGO:19017002000.022
glycosyl compound metabolic processGO:19016571270.022
single organism intracellular transportGO:19025822070.022
positive regulation of catalytic activityGO:00430851180.022
negative regulation of signalingGO:00230572190.022
positive regulation of molecular functionGO:00440931360.022
catabolic processGO:00090564090.022
carbohydrate metabolic processGO:0005975820.021
positive regulation of lipid storageGO:001088440.021
regulation of gtpase activityGO:0043087440.021
response to lipopolysaccharideGO:003249640.021
eye morphogenesisGO:00485922600.021
chromatin organizationGO:00063252070.021
rna processingGO:00063961470.021
positive regulation of gene expressionGO:00106282900.021
lipid localizationGO:0010876540.021
gland developmentGO:00487321910.021
regulation of neurogenesisGO:00507671580.021
regulation of mapk cascadeGO:0043408920.020
cellular response to extracellular stimulusGO:0031668640.020
gland morphogenesisGO:00226121450.020
negative regulation of phosphorus metabolic processGO:0010563450.020
regulation of apoptotic processGO:00429811300.019
organic substance catabolic processGO:19015753080.019
positive regulation of cellular catabolic processGO:0031331950.019
regulation of cellular protein metabolic processGO:00322682430.019
endomembrane system organizationGO:00102561190.019
organophosphate catabolic processGO:00464341120.019
regulation of cell deathGO:00109411730.019
programmed cell deathGO:00125012570.019
regulation of neurotransmitter levelsGO:0001505380.019
Worm
covalent chromatin modificationGO:00165691060.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
purine containing compound catabolic processGO:00725231120.019
ribonucleoside triphosphate metabolic processGO:00091991190.018
regulation of hydrolase activityGO:0051336970.018
aromatic compound catabolic processGO:00194391660.018
secretionGO:00469031090.018
Worm
actin cytoskeleton organizationGO:00300362060.018
organonitrogen compound catabolic processGO:19015651280.018
regulation of developmental growthGO:00486381740.018
body morphogenesisGO:001017120.018
positive regulation of rna biosynthetic processGO:19026802660.018
positive regulation of catabolic processGO:00098961050.018
positive regulation of mapk cascadeGO:0043410630.018
oocyte maturationGO:000155630.018
regulation of response to stressGO:00801342000.018
regulation of molecular functionGO:00650092170.018
developmental pigmentationGO:0048066680.018
gtp metabolic processGO:0046039720.018
photoreceptor cell fate commitmentGO:0046552410.018
regulation of cell cycleGO:00517262910.017
secretion by cellGO:00329401010.017
Worm
negative regulation of cell deathGO:0060548810.017
macromolecule catabolic processGO:00090571610.017
single organism carbohydrate metabolic processGO:0044723720.017
regulation of cellular amino acid metabolic processGO:000652100.017
negative regulation of cell differentiationGO:00455961430.017
response to lipidGO:0033993380.017
regulation of cellular amine metabolic processGO:003323830.017
negative regulation of rna metabolic processGO:00512532510.017
skin developmentGO:0043588650.017
learning or memoryGO:00076111410.017
regulation of programmed cell deathGO:00430671520.016
detection of light stimulusGO:0009583580.016
eye photoreceptor cell differentiationGO:00017541450.016
vesicle mediated transportGO:00161923810.016
response to abiotic stimulusGO:00096283410.016
regulation of organelle organizationGO:00330431960.016
oxidation reduction processGO:00551141230.016
cellular nitrogen compound catabolic processGO:00442701650.016
signal transduction by phosphorylationGO:00230141070.016
positive regulation of protein metabolic processGO:00512471280.015
negative regulation of cell communicationGO:00106482230.015
morphogenesis of a polarized epitheliumGO:0001738930.015
cellular response to nutrient levelsGO:0031669620.015
regulation of catalytic activityGO:00507901850.015
positive regulation of gtpase activityGO:0043547430.015
nucleoside triphosphate metabolic processGO:00091411200.015
positive regulation of purine nucleotide metabolic processGO:1900544550.015
cellular response to lipopolysaccharideGO:007122230.015
eye antennal disc developmentGO:0035214600.015
macroautophagyGO:0016236420.015
multi multicellular organism processGO:00447061230.015
response to other organismGO:00517072930.015
regulation of erk1 and erk2 cascadeGO:0070372390.015
heterocycle catabolic processGO:00467001660.014
regulation of cytoskeleton organizationGO:0051493890.014
negative regulation of cellular protein metabolic processGO:0032269850.014
neurological system processGO:00508773580.014
chaeta developmentGO:0022416970.014
ethanolamine containing compound metabolic processGO:004243940.014
positive regulation of transcription dna templatedGO:00458932660.014
digestive tract morphogenesisGO:00485461270.014
response to heatGO:0009408630.014
negative regulation of biosynthetic processGO:00098902770.014
organic cyclic compound catabolic processGO:19013611680.014
pigment metabolic process involved in pigmentationGO:0043474330.014
multicellular organismal reproductive behaviorGO:00330571100.014
positive regulation of gtp catabolic processGO:0033126430.014
salivary gland cell autophagic cell deathGO:0035071830.014
ribonucleotide metabolic processGO:00092591450.014
protein modification by small protein conjugationGO:0032446790.014
regulation of protein modification processGO:00313991120.013
compound eye photoreceptor cell differentiationGO:00017511400.013
embryo development ending in birth or egg hatchingGO:00097921520.013
regulation of neuron differentiationGO:00456641030.013
regulation of purine nucleotide catabolic processGO:0033121480.013
mrna metabolic processGO:00160711240.013
glycerophospholipid metabolic processGO:0006650230.013
lipid storageGO:0019915380.013
tube developmentGO:00352952440.013
organelle localizationGO:00516401480.013
negative regulation of protein metabolic processGO:0051248850.013
neuron fate commitmentGO:0048663500.013
nuclear body organizationGO:003057560.013
cellular response to organic substanceGO:00713101320.013
negative regulation of gene expressionGO:00106293870.013
positive regulation of erk1 and erk2 cascadeGO:0070374360.012
response to copper ionGO:004668840.012
carbohydrate derivative biosynthetic processGO:1901137850.012
salivary gland morphogenesisGO:00074351450.012
apoptotic processGO:00069151590.012
glycoprotein biosynthetic processGO:0009101410.012
gtp catabolic processGO:0006184720.012
exocrine system developmentGO:00352721620.012
phosphatidylethanolamine metabolic processGO:004633710.012
nucleoside metabolic processGO:00091161270.012
purine ribonucleotide catabolic processGO:00091541090.012
positive regulation of nucleotide catabolic processGO:0030813460.012
ribonucleotide catabolic processGO:00092611090.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
phagocytosisGO:00069092150.012
regulation of neuron projection developmentGO:0010975690.012
epithelial cell developmentGO:00020642740.012
nucleoside phosphate catabolic processGO:19012921100.012
cellular response to dna damage stimulusGO:00069742230.012
regulation of endopeptidase activityGO:0052548360.012
digestive tract developmentGO:00485651490.012
flight behaviorGO:0007629260.011
regulation of nucleoside metabolic processGO:0009118500.011
agingGO:00075681430.011
regulation of cellular component movementGO:0051270420.011
regulation of erbb signaling pathwayGO:1901184420.011
notch signaling pathwayGO:00072191200.011
immune system developmentGO:0002520570.011
negative regulation of nucleobase containing compound metabolic processGO:00459342610.011
female germ line cyst formationGO:0048135420.011
purine containing compound metabolic processGO:00725211550.011
rna 3 end processingGO:0031123450.011
ribonucleoside triphosphate catabolic processGO:00092031080.011
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.011
developmental growthGO:00485892800.011
purine nucleotide catabolic processGO:00061951090.011
regulation of mrna metabolic processGO:1903311720.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
compound eye photoreceptor fate commitmentGO:0001752360.011
regulation of gtp catabolic processGO:0033124440.011
response to organic cyclic compoundGO:0014070890.011
eye photoreceptor cell fate commitmentGO:0042706370.011
salivary gland developmentGO:00074311620.011
neurotransmitter transportGO:0006836370.011
Worm
positive regulation of nucleotide metabolic processGO:0045981550.011
positive regulation of transportGO:0051050920.011
Worm
protein transportGO:00150311550.011
regulation of nucleotide metabolic processGO:0006140620.010
guanosine containing compound catabolic processGO:1901069740.010
gliogenesisGO:0042063800.010
glycoprotein metabolic processGO:0009100410.010
ovarian follicle cell migrationGO:00072971210.010
spindle organizationGO:00070512530.010
purine nucleoside catabolic processGO:00061521120.010
regulation of cell motilityGO:2000145230.010
synaptic transmissionGO:00072682880.010
Worm
regulation of cell developmentGO:00602842150.010
regulation of multi organism processGO:00439001310.010
regulation of protein phosphorylationGO:0001932640.010
mrna 3 end processingGO:0031124280.010
long chain fatty acid metabolic processGO:000167630.010
positive regulation of cell deathGO:0010942690.010
regulation of cell migrationGO:0030334220.010
mrna processingGO:00063971040.010

Sk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.029