IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG3815 (Dmel_CG3815)

CG3815 gene product from transcript CG3815-RA

(Aliases: PF1,Pf1,Dmel\CG3815)

Entrez: 31571
FLYBASE: FBgn0029861
UniProtKB: Q9W410

Process Predictions
Disease Predictions

CG3815 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.560
negative regulation of rna biosynthetic process	GO:1902679	240	0.429	Human
negative regulation of transcription dna templated	GO:0045892	237	0.405	Human
positive regulation of macromolecule metabolic process	GO:0010604	405	0.322
dna metabolic process	GO:0006259	227	0.230
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.208
positive regulation of rna biosynthetic process	GO:1902680	266	0.207
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.193	Human
negative regulation of gene expression epigenetic	GO:0045814	77	0.172
negative regulation of biosynthetic process	GO:0009890	277	0.170	Human
positive regulation of biosynthetic process	GO:0009891	316	0.159
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.152	Human
transcription from rna polymerase ii promoter	GO:0006366	368	0.149	Human
regionalization	GO:0003002	416	0.141
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.139
positive regulation of rna metabolic process	GO:0051254	271	0.133
negative regulation of gene expression	GO:0010629	387	0.127	Human
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.126	Human
positive regulation of cellular biosynthetic process	GO:0031328	316	0.120
positive regulation of gene expression	GO:0010628	290	0.119
negative regulation of rna metabolic process	GO:0051253	251	0.119	Human
positive regulation of transcription dna templated	GO:0045893	266	0.118
regulation of gene expression epigenetic	GO:0040029	128	0.116
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.112
negative regulation of cellular metabolic process	GO:0031324	382	0.109	Human
organelle fission	GO:0048285	340	0.102
chromatin organization	GO:0006325	207	0.102
gene silencing	GO:0016458	138	0.101
chromatin silencing	GO:0006342	76	0.094
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.093
establishment or maintenance of cell polarity	GO:0007163	167	0.092
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.091	Human
chromosome organization	GO:0051276	360	0.091
tissue morphogenesis	GO:0048729	297	0.087
cell proliferation	GO:0008283	299	0.084
nuclear division	GO:0000280	332	0.082
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.079	Human
regulation of cell differentiation	GO:0045595	302	0.078
protein modification process	GO:0036211	438	0.070
dna conformation change	GO:0071103	105	0.063
cellular protein modification process	GO:0006464	438	0.062
axon development	GO:0061564	297	0.061
chromatin modification	GO:0016568	147	0.055
cell division	GO:0051301	248	0.052
imaginal disc derived appendage development	GO:0048737	399	0.049
central nervous system development	GO:0007417	201	0.048
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.047	Human
cellular catabolic process	GO:0044248	372	0.047
death	GO:0016265	284	0.047
cellular response to dna damage stimulus	GO:0006974	223	0.046
negative regulation of signaling	GO:0023057	219	0.046
chromosome segregation	GO:0007059	157	0.045
negative regulation of signal transduction	GO:0009968	206	0.044
regulation of cell proliferation	GO:0042127	163	0.043
negative regulation of cell communication	GO:0010648	223	0.043
regulation of localization	GO:0032879	275	0.042
dendrite development	GO:0016358	204	0.042
cell death	GO:0008219	279	0.041
negative regulation of cellular biosynthetic process	GO:0031327	277	0.040	Human
response to alcohol	GO:0097305	95	0.040
dendrite morphogenesis	GO:0048813	199	0.039
response to organic substance	GO:0010033	284	0.038
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.037
regulation of multicellular organismal development	GO:2000026	414	0.037
regulation of cell cycle	GO:0051726	291	0.036
meiotic nuclear division	GO:0007126	151	0.036
stem cell division	GO:0017145	69	0.036
negative regulation of response to stimulus	GO:0048585	258	0.035
endocytosis	GO:0006897	310	0.035
dna recombination	GO:0006310	32	0.035
covalent chromatin modification	GO:0016569	106	0.034
phosphorylation	GO:0016310	294	0.034
regulation of apoptotic process	GO:0042981	130	0.033
positive regulation of cellular amine metabolic process	GO:0033240	0	0.032
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.032	Human
developmental programmed cell death	GO:0010623	138	0.032
morphogenesis of an epithelium	GO:0002009	276	0.031
meiotic chromosome segregation	GO:0045132	59	0.031
regulation of gene silencing	GO:0060968	63	0.031
appendage morphogenesis	GO:0035107	397	0.031
dna replication	GO:0006260	48	0.030
camera type eye development	GO:0043010	4	0.030
regulation of anatomical structure morphogenesis	GO:0022603	242	0.029
regulation of organelle organization	GO:0033043	196	0.029
taxis	GO:0042330	304	0.029
biological adhesion	GO:0022610	138	0.029
regulation of chromatin silencing	GO:0031935	36	0.028
exocrine system development	GO:0035272	162	0.028
regulation of programmed cell death	GO:0043067	152	0.028
vesicle mediated transport	GO:0016192	381	0.028
organonitrogen compound metabolic process	GO:1901564	318	0.027
asymmetric stem cell division	GO:0098722	49	0.027
protein phosphorylation	GO:0006468	169	0.027
chromatin remodeling	GO:0006338	72	0.027
eye development	GO:0001654	323	0.027
guanosine containing compound metabolic process	GO:1901068	74	0.025
compound eye development	GO:0048749	307	0.025
post embryonic appendage morphogenesis	GO:0035120	385	0.025
wing disc morphogenesis	GO:0007472	344	0.025
single organism biosynthetic process	GO:0044711	206	0.024
peptidyl lysine modification	GO:0018205	57	0.024
response to oxygen containing compound	GO:1901700	200	0.024
macromolecular complex assembly	GO:0065003	256	0.024
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.024
embryonic development via the syncytial blastoderm	GO:0001700	148	0.024
positive regulation of phosphorus metabolic process	GO:0010562	139	0.024
anterior posterior pattern specification	GO:0009952	136	0.023
nucleobase containing compound catabolic process	GO:0034655	165	0.023
stem cell differentiation	GO:0048863	117	0.023
developmental growth	GO:0048589	280	0.023
mitotic nuclear division	GO:0007067	213	0.023
stem cell proliferation	GO:0072089	88	0.023
camera type eye morphogenesis	GO:0048593	2	0.023
dorsal ventral pattern formation	GO:0009953	133	0.022
sister chromatid segregation	GO:0000819	92	0.022
small molecule metabolic process	GO:0044281	305	0.022
appendage development	GO:0048736	401	0.022
actin filament based process	GO:0030029	220	0.022
ras protein signal transduction	GO:0007265	88	0.022
localization of cell	GO:0051674	257	0.022
double strand break repair	GO:0006302	26	0.022
regulation of intracellular signal transduction	GO:1902531	236	0.022
apoptotic process	GO:0006915	159	0.021
regulation of cell morphogenesis	GO:0022604	163	0.021
regulation of molecular function	GO:0065009	217	0.021
neural precursor cell proliferation	GO:0061351	75	0.021
response to abiotic stimulus	GO:0009628	341	0.021
anatomical structure homeostasis	GO:0060249	97	0.021
developmental maturation	GO:0021700	172	0.021
regulation of neurogenesis	GO:0050767	158	0.021
response to organic cyclic compound	GO:0014070	89	0.021
aromatic compound catabolic process	GO:0019439	166	0.020
locomotory behavior	GO:0007626	176	0.020
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.020
tripartite regional subdivision	GO:0007351	103	0.020
circadian behavior	GO:0048512	76	0.020
cellular response to extracellular stimulus	GO:0031668	64	0.019
immune system process	GO:0002376	347	0.019
positive regulation of signal transduction	GO:0009967	223	0.019
programmed cell death	GO:0012501	257	0.019
muscle organ development	GO:0007517	127	0.019
cellular macromolecule localization	GO:0070727	220	0.019
neuroblast division	GO:0055057	35	0.019
regulation of cell development	GO:0060284	215	0.019
cell motility	GO:0048870	251	0.019
axon guidance	GO:0007411	233	0.019
axis specification	GO:0009798	167	0.019
cell adhesion	GO:0007155	136	0.019
centrosome organization	GO:0051297	163	0.018
organic substance catabolic process	GO:1901575	308	0.018
cellular response to organic substance	GO:0071310	132	0.018
actin cytoskeleton organization	GO:0030036	206	0.018
neuron recognition	GO:0008038	101	0.018
phagocytosis	GO:0006909	215	0.018
regulation of nervous system development	GO:0051960	248	0.018
gland development	GO:0048732	191	0.018
response to radiation	GO:0009314	155	0.018
regulation of cellular amine metabolic process	GO:0033238	3	0.018
neuron projection guidance	GO:0097485	241	0.018
histone modification	GO:0016570	106	0.018
salivary gland development	GO:0007431	162	0.018
microtubule organizing center organization	GO:0031023	168	0.018
regulation of chromosome organization	GO:0033044	64	0.018
meiosis i	GO:0007127	59	0.018
cellular amino acid metabolic process	GO:0006520	61	0.018
chemotaxis	GO:0006935	249	0.017
open tracheal system development	GO:0007424	204	0.017
cellular macromolecule catabolic process	GO:0044265	136	0.017
dna repair	GO:0006281	54	0.017
sensory organ morphogenesis	GO:0090596	260	0.017
negative regulation of programmed cell death	GO:0043069	72	0.017
cell migration	GO:0016477	238	0.017
regulation of cellular component size	GO:0032535	98	0.017
meiotic cell cycle process	GO:1903046	132	0.017
oocyte development	GO:0048599	124	0.017
regulation of cell shape	GO:0008360	113	0.017
body morphogenesis	GO:0010171	2	0.017
neuroblast proliferation	GO:0007405	74	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
carboxylic acid metabolic process	GO:0019752	92	0.017
anterior posterior axis specification	GO:0009948	109	0.017
ribonucleoside metabolic process	GO:0009119	127	0.017
salivary gland histolysis	GO:0035070	88	0.017
wing disc pattern formation	GO:0035222	66	0.016
intracellular signal transduction	GO:0035556	300	0.016
organic acid metabolic process	GO:0006082	103	0.016
negative regulation of cellular component organization	GO:0051129	108	0.016
amine metabolic process	GO:0009308	12	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016
negative regulation of apoptotic process	GO:0043066	63	0.016
digestive system development	GO:0055123	149	0.016
positive regulation of cell communication	GO:0010647	250	0.016
single organism catabolic process	GO:0044712	228	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
small gtpase mediated signal transduction	GO:0007264	88	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
regulation of protein modification process	GO:0031399	112	0.015
epithelial cell differentiation	GO:0030855	322	0.015
meiotic cell cycle	GO:0051321	171	0.015
axonogenesis	GO:0007409	290	0.015
regulation of cell division	GO:0051302	72	0.015
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
growth	GO:0040007	359	0.015
tissue migration	GO:0090130	155	0.015
cell cycle dna replication	GO:0044786	23	0.015
peptidyl amino acid modification	GO:0018193	105	0.015
homeostatic process	GO:0042592	199	0.015
oxoacid metabolic process	GO:0043436	103	0.015
embryonic morphogenesis	GO:0048598	206	0.015
regulation of cell cycle process	GO:0010564	181	0.015
mitotic cell cycle phase transition	GO:0044772	138	0.015
response to light stimulus	GO:0009416	124	0.015
ameboidal type cell migration	GO:0001667	151	0.015
regulation of cellular ketone metabolic process	GO:0010565	3	0.015
tissue death	GO:0016271	102	0.015
histolysis	GO:0007559	102	0.015
gland morphogenesis	GO:0022612	145	0.015
cytoskeleton dependent cytokinesis	GO:0061640	81	0.014
positive regulation of molecular function	GO:0044093	136	0.014
retina development in camera type eye	GO:0060041	4	0.014
somatic stem cell division	GO:0048103	37	0.014
dna dependent dna replication	GO:0006261	17	0.014
establishment of localization in cell	GO:0051649	402	0.014
oocyte maturation	GO:0001556	3	0.014
double strand break repair via homologous recombination	GO:0000724	13	0.014
regulation of catabolic process	GO:0009894	170	0.014
tube development	GO:0035295	244	0.014
positive regulation of gtpase activity	GO:0043547	43	0.014
imaginal disc derived wing morphogenesis	GO:0007476	337	0.014
cellular amine metabolic process	GO:0044106	12	0.014
regulation of catalytic activity	GO:0050790	185	0.013
response to lipopolysaccharide	GO:0032496	4	0.013
cellular ketone metabolic process	GO:0042180	24	0.013
regulation of ras protein signal transduction	GO:0046578	93	0.013
regulation of anatomical structure size	GO:0090066	163	0.013
regulation of cellular catabolic process	GO:0031329	157	0.013
catabolic process	GO:0009056	409	0.013
heterocycle catabolic process	GO:0046700	166	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.013
oocyte dorsal ventral axis specification	GO:0007310	34	0.013
forebrain development	GO:0030900	2	0.013
nucleotide metabolic process	GO:0009117	161	0.013
response to other organism	GO:0051707	293	0.013
telomere organization	GO:0032200	21	0.013
respiratory system development	GO:0060541	213	0.013
positive regulation of signaling	GO:0023056	243	0.013
imaginal disc derived leg morphogenesis	GO:0007480	80	0.013
positive regulation of hydrolase activity	GO:0051345	78	0.013
cellular protein localization	GO:0034613	160	0.013
negative regulation of developmental process	GO:0051093	201	0.013
dna packaging	GO:0006323	91	0.013
response to biotic stimulus	GO:0009607	294	0.012
carbohydrate derivative metabolic process	GO:1901135	217	0.012
larval development	GO:0002164	104	0.012
positive regulation of nucleotide catabolic process	GO:0030813	46	0.012
intracellular transport	GO:0046907	228	0.012
regulation of transport	GO:0051049	181	0.012
positive regulation of nucleoside metabolic process	GO:0045979	47	0.012
single organism intracellular transport	GO:1902582	207	0.012
eye morphogenesis	GO:0048592	260	0.012
regulation of nucleoside metabolic process	GO:0009118	50	0.012
compound eye morphogenesis	GO:0001745	249	0.012
female meiotic division	GO:0007143	70	0.012
regulation of cell death	GO:0010941	173	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
negative regulation of cell death	GO:0060548	81	0.012
neuronal stem cell division	GO:0036445	35	0.012
negative regulation of protein depolymerization	GO:1901880	23	0.012
branching morphogenesis of an epithelial tube	GO:0048754	45	0.012
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.012
purine ribonucleotide catabolic process	GO:0009154	109	0.012
rhythmic process	GO:0048511	106	0.012
cell fate specification	GO:0001708	71	0.012
epidermis development	GO:0008544	65	0.012
asymmetric neuroblast division	GO:0055059	33	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.012
embryo development ending in birth or egg hatching	GO:0009792	152	0.012
cellular response to biotic stimulus	GO:0071216	4	0.012
purine containing compound metabolic process	GO:0072521	155	0.012
regulation of gtpase activity	GO:0043087	44	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.011
male gamete generation	GO:0048232	201	0.011
compound eye photoreceptor cell differentiation	GO:0001751	140	0.011
g protein coupled receptor signaling pathway	GO:0007186	136	0.011
autophagic cell death	GO:0048102	83	0.011
regulation of mitosis	GO:0007088	56	0.011
negative regulation of cell proliferation	GO:0008285	69	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
humoral immune response	GO:0006959	117	0.011
photoreceptor cell differentiation	GO:0046530	170	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
leg disc development	GO:0035218	92	0.011
cell recognition	GO:0008037	102	0.011
reproductive structure development	GO:0048608	74	0.011
mitotic g2 dna damage checkpoint	GO:0007095	69	0.011
cellular response to radiation	GO:0071478	52	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011
establishment of cell polarity	GO:0030010	40	0.011
mitotic spindle organization	GO:0007052	220	0.011
head development	GO:0060322	135	0.011
cellular response to abiotic stimulus	GO:0071214	58	0.011
neurological system process	GO:0050877	358	0.011
digestive tract development	GO:0048565	149	0.011
segmentation	GO:0035282	207	0.011
cellular response to organic cyclic compound	GO:0071407	32	0.011
male meiosis	GO:0007140	52	0.011
oocyte differentiation	GO:0009994	145	0.011
protein dna complex subunit organization	GO:0071824	86	0.011
digestive tract morphogenesis	GO:0048546	127	0.011
microtubule based transport	GO:0010970	42	0.011
glycosyl compound metabolic process	GO:1901657	127	0.010
regulation of phosphorylation	GO:0042325	147	0.010
response to endogenous stimulus	GO:0009719	119	0.010
response to external biotic stimulus	GO:0043207	293	0.010
actin filament organization	GO:0007015	126	0.010
protein depolymerization	GO:0051261	31	0.010
skin development	GO:0043588	65	0.010
muscle cell differentiation	GO:0042692	103	0.010
pole cell development	GO:0007277	26	0.010
centrosome cycle	GO:0007098	137	0.010
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.010
regulation of dna metabolic process	GO:0051052	34	0.010
organophosphate metabolic process	GO:0019637	195	0.010
nucleoside triphosphate metabolic process	GO:0009141	120	0.010
recombinational repair	GO:0000725	13	0.010
atp dependent chromatin remodeling	GO:0043044	22	0.010
protein alkylation	GO:0008213	43	0.010
histone deacetylation	GO:0016575	9	0.010

CG3815 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.022
disease of anatomical entity	DOID:7	0.021
cancer	DOID:162	0.021
organ system cancer	DOID:0050686	0.021

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