Drosophila melanogaster

99 known processes

h (Dmel_CG6494)

hairy

(Aliases: Hairy,l(3)rM384,HRY,Dmel\CG6494,dDr1,brr,bHLHc14,l(3)08247,CG6494,bHLHb39,8247)

h biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of transcription dna templatedGO:00458922370.972
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.797
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.795
Mouse
negative regulation of macromolecule biosynthetic processGO:00105582700.782
negative regulation of rna metabolic processGO:00512532510.703
negative regulation of cellular biosynthetic processGO:00313272770.700
negative regulation of gene expressionGO:00106293870.668
positive regulation of transcription dna templatedGO:00458932660.661
Mouse
positive regulation of biosynthetic processGO:00098913160.605
Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072400.556
regulation of transcription from rna polymerase ii promoterGO:00063573780.551
negative regulation of nucleobase containing compound metabolic processGO:00459342610.549
positive regulation of cellular biosynthetic processGO:00313283160.533
Mouse
negative regulation of rna biosynthetic processGO:19026792400.530
negative regulation of nitrogen compound metabolic processGO:00511722650.501
transcription from rna polymerase ii promoterGO:00063663680.484
organic acid metabolic processGO:00060821030.480
negative regulation of biosynthetic processGO:00098902770.396
positive regulation of nucleic acid templated transcriptionGO:19035082660.389
Mouse
spermatid developmentGO:0007286980.381
positive regulation of macromolecule biosynthetic processGO:00105572830.336
Mouse
cell proliferationGO:00082832990.313
Mouse Fly
regulation of protein metabolic processGO:00512462560.311
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.306
Mouse
immune system processGO:00023763470.256
Human Mouse
organonitrogen compound metabolic processGO:19015643180.251
negative regulation of cellular metabolic processGO:00313243820.241
negative regulation of cell communicationGO:00106482230.211
protein localizationGO:00081042840.208
Mouse
spermatid differentiationGO:00485151140.189
positive regulation of nitrogen compound metabolic processGO:00511733540.185
Mouse
regulation of localizationGO:00328792750.183
epithelial cell differentiationGO:00308553220.156
Mouse Worm
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.154
positive regulation of response to stimulusGO:00485843230.154
Mouse
establishment of localization in cellGO:00516494020.149
Mouse
protein complex assemblyGO:00064612000.136
Mouse
positive regulation of macromolecule metabolic processGO:00106044050.136
Mouse
protein modification processGO:00362114380.123
Mouse
regulation of protein transportGO:0051223570.121
response to abiotic stimulusGO:00096283410.120
phosphorylationGO:00163102940.117
Mouse
positive regulation of rna biosynthetic processGO:19026802660.113
Mouse
regulation of response to stressGO:00801342000.110
Fly
carboxylic acid metabolic processGO:0019752920.107
positive regulation of signalingGO:00230562430.107
Mouse
intracellular signal transductionGO:00355563000.107
Mouse
positive regulation of rna metabolic processGO:00512542710.104
Mouse
male gamete generationGO:00482322010.102
dendrite developmentGO:00163582040.102
Fly
dorsal ventral pattern formationGO:00099531330.100
Fly
dna metabolic processGO:00062592270.099
histone modificationGO:00165701060.099
oxoacid metabolic processGO:00434361030.095
chromosome organizationGO:00512763600.094
positive regulation of gene expressionGO:00106282900.093
Mouse
body morphogenesisGO:001017120.090
regulation of protein localizationGO:0032880760.089
regulation of phosphorus metabolic processGO:00511742100.085
Mouse
regulation of transportGO:00510491810.085
macromolecular complex assemblyGO:00650032560.085
Mouse
small molecule metabolic processGO:00442813050.084
cytoplasmic transportGO:00164821300.083
Mouse
spermatogenesisGO:00072832000.082
brain developmentGO:00074201200.081
Zebrafish Mouse Fly
catabolic processGO:00090564090.080
chromatin organizationGO:00063252070.080
macromolecule catabolic processGO:00090571610.078
head developmentGO:00603221350.076
Zebrafish Mouse Fly
gene silencingGO:00164581380.076
response to endogenous stimulusGO:00097191190.075
gland developmentGO:00487321910.073
sensory perception of mechanical stimulusGO:0050954720.073
intracellular transportGO:00469072280.072
Mouse
mitotic nuclear divisionGO:00070672130.072
Fly
cellular response to organic substanceGO:00713101320.072
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.071
Mouse
muscle structure developmentGO:00610612240.070
Mouse
positive regulation of cell communicationGO:00106472500.069
Mouse
negative regulation of response to stimulusGO:00485852580.066
regulation of anatomical structure morphogenesisGO:00226032420.065
Mouse
protein acetylationGO:0006473390.064
regulation of phosphate metabolic processGO:00192202100.064
Mouse
cellular protein localizationGO:00346131600.062
Mouse
post embryonic appendage morphogenesisGO:00351203850.062
response to organic substanceGO:00100332840.060
regulation of cellular localizationGO:00603411360.059
positive regulation of signal transductionGO:00099672230.058
Mouse
protein transportGO:00150311550.058
Mouse
regulation of multi organism processGO:00439001310.057
single organism biosynthetic processGO:00447112060.057
organic substance transportGO:00717022570.057
Mouse
cellular response to chemical stimulusGO:00708871990.056
regulation of cellular response to stressGO:0080135890.055
Fly
notch signaling pathwayGO:00072191200.054
Human Zebrafish Mouse Fly
positive regulation of cellular component organizationGO:00511301560.053
Fly
photoreceptor cell differentiationGO:00465301700.053
Fly
cellular macromolecule localizationGO:00707272200.052
Mouse
organic substance catabolic processGO:19015753080.052
g2 dna damage checkpointGO:0031572690.049
regulation of epithelial cell differentiationGO:003085640.049
Mouse
transforming growth factor beta receptor signaling pathwayGO:0007179160.049
regulation of cellular protein metabolic processGO:00322682430.049
Mouse
regulation of organelle organizationGO:00330431960.048
Fly
regulation of cell proliferationGO:00421271630.047
Mouse Fly
negative regulation of signal transductionGO:00099682060.047
negative regulation of cell cycle processGO:00109481090.044
positive regulation of protein metabolic processGO:00512471280.044
Mouse
positive regulation of multicellular organismal processGO:00512401430.044
Mouse Fly
regulation of catabolic processGO:00098941700.043
proteolysisGO:00065081920.042
regulation of gene expression epigeneticGO:00400291280.042
Fly
chromatin silencingGO:0006342760.042
establishment of protein localizationGO:00451841630.042
Mouse
cellular response to dna damage stimulusGO:00069742230.042
Fly
regulation of immune responseGO:00507761180.041
posttranscriptional gene silencingGO:0016441460.040
centrosome organizationGO:00512971630.040
nuclear transportGO:0051169720.040
Mouse
cellular catabolic processGO:00442483720.040
peptidyl threonine phosphorylationGO:001810720.040
organelle fissionGO:00482853400.039
Fly
protein modification by small protein conjugation or removalGO:00706471060.039
cellular response to transforming growth factor beta stimulusGO:0071560180.039
positive regulation of cell differentiationGO:0045597640.037
Mouse Fly
protein complex biogenesisGO:00702712010.037
Mouse
regulation of cellular response to growth factor stimulusGO:0090287130.037
hindbrain developmentGO:003090220.036
Mouse
single organism intracellular transportGO:19025822070.036
Mouse
stem cell differentiationGO:00488631170.036
Human Mouse
forebrain developmentGO:003090020.036
Zebrafish Mouse
protein localization to organelleGO:0033365820.035
Mouse
immune system developmentGO:0002520570.035
Human Mouse
regulation of cell deathGO:00109411730.035
response to bacteriumGO:00096171980.034
regulation of cell differentiationGO:00455953020.034
Human Zebrafish Mouse Fly
jak stat cascadeGO:0007259490.033
Mouse
muscle organ developmentGO:00075171270.033
response to lipopolysaccharideGO:003249640.032
posttranscriptional regulation of gene expressionGO:00106081450.031
carbohydrate derivative metabolic processGO:19011352170.031
cellular macromolecule catabolic processGO:00442651360.030
innate immune responseGO:00450871440.030
enzyme linked receptor protein signaling pathwayGO:00071671790.029
Mouse
secretionGO:00469031090.029
regulation of establishment of protein localizationGO:0070201610.029
regulation of intracellular transportGO:0032386640.028
positive regulation of immune system processGO:0002684680.028
Mouse
organic cyclic compound catabolic processGO:19013611680.028
response to other organismGO:00517072930.028
cellular response to endogenous stimulusGO:0071495800.028
protein catabolic processGO:00301631010.027
regulation of response to external stimulusGO:00321011150.027
regulation of notch signaling pathwayGO:00085931000.027
Mouse
cellular response to oxygen containing compoundGO:1901701790.027
stem cell maintenanceGO:0019827670.027
Human Mouse
regulation of protein catabolic processGO:0042176550.027
cellular protein modification processGO:00064644380.026
Mouse
hemopoiesisGO:0030097460.026
Human
protein ubiquitinationGO:0016567700.026
stem cell developmentGO:0048864790.026
Human Mouse
mitochondrion organizationGO:0007005650.025
regulation of gene silencingGO:0060968630.025
skin developmentGO:0043588650.025
Mouse Worm
imaginal disc pattern formationGO:0007447910.025
Fly
nucleocytoplasmic transportGO:0006913720.025
Mouse
developmental growthGO:00485892800.024
positive regulation of cell deathGO:0010942690.024
regulation of bmp signaling pathwayGO:0030510230.023
Mouse
negative regulation of cell proliferationGO:0008285690.023
Mouse
positive regulation of cell developmentGO:0010720610.023
Mouse Fly
monocarboxylic acid metabolic processGO:0032787290.023
response to growth factorGO:0070848310.023
regulation of proteolysisGO:0030162870.023
regulation of response to dna damage stimulusGO:2001020230.023
Fly
hematopoietic or lymphoid organ developmentGO:0048534570.023
Human Mouse
positive regulation of intracellular signal transductionGO:19025331160.022
Mouse
protein k48 linked ubiquitinationGO:007093630.022
response to biotic stimulusGO:00096072940.022
columnar cuboidal epithelial cell differentiationGO:00020652560.022
Mouse
positive regulation of cell proliferationGO:0008284470.022
Mouse Fly
single organism cellular localizationGO:19025801800.022
Mouse
embryonic development via the syncytial blastodermGO:00017001480.022
dna damage checkpointGO:0000077780.022
negative regulation of immune system processGO:0002683500.021
Human
protein localization to nucleusGO:0034504550.021
Mouse
tissue morphogenesisGO:00487292970.021
Mouse
cellular protein complex assemblyGO:0043623710.021
cellular response to growth factor stimulusGO:0071363300.021
negative regulation of cell cycleGO:00457861160.021
response to transforming growth factor betaGO:0071559180.021
single organism catabolic processGO:00447122280.020
positive regulation of notch signaling pathwayGO:0045747340.020
Mouse
cell divisionGO:00513012480.020
Fly
regulation of molecular functionGO:00650092170.020
Mouse
nucleobase containing small molecule metabolic processGO:00550861740.019
gland morphogenesisGO:00226121450.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
Mouse
negative regulation of mitotic cell cycle phase transitionGO:19019911030.019
regulation of multicellular organismal developmentGO:20000264140.019
Human Zebrafish Mouse Fly
intracellular protein transportGO:00068861040.019
Mouse
positive regulation of ras protein signal transductionGO:0046579430.019
regulation of mitotic cell cycleGO:00073461900.019
Mouse Fly
regionalizationGO:00030024160.019
Zebrafish Mouse Worm Fly
regulation of chromatin silencingGO:0031935360.019
larval behaviorGO:0030537420.019
Fly
ras protein signal transductionGO:0007265880.019
regulation of immune effector processGO:0002697520.018
protein deubiquitinationGO:0016579170.018
protein targeting to nucleusGO:0044744510.018
Mouse
vesicle mediated transportGO:00161923810.018
regulation of cytoplasmic transportGO:1903649470.018
microtubule organizing center organizationGO:00310231680.018
cellular component assembly involved in morphogenesisGO:00109271510.018
protein modification by small protein removalGO:0070646280.018
regulation of intracellular signal transductionGO:19025312360.018
Mouse
positive regulation of immune responseGO:0050778630.018
nephron tubule developmentGO:007208030.017
Mouse
regulation of cellular ketone metabolic processGO:001056530.017
connective tissue developmentGO:006144830.017
positive regulation of catabolic processGO:00098961050.017
neurological system processGO:00508773580.017
Fly
single organism behaviorGO:00447083910.017
Fly
cell deathGO:00082192790.017
mitotic g2 m transition checkpointGO:0044818700.017
endomembrane system organizationGO:00102561190.017
smoothened signaling pathwayGO:0007224490.016
Mouse
response to nitrogen compoundGO:1901698900.016
regulation of immune system processGO:00026821760.016
Human Mouse
negative regulation of gene expression epigeneticGO:0045814770.016
programmed cell deathGO:00125012570.016
positive regulation of cell motilityGO:200014730.016
small gtpase mediated signal transductionGO:0007264880.016
nuclear divisionGO:00002803320.016
Fly
regulation of cellular catabolic processGO:00313291570.015
aromatic compound catabolic processGO:00194391660.015
immune response regulating signaling pathwayGO:000276420.015
negative regulation of mitotic cell cycleGO:00459301090.015
exocrine system developmentGO:00352721620.015
apoptotic processGO:00069151590.015
hematopoietic progenitor cell differentiationGO:000224410.015
Human
mitotic cell cycle checkpointGO:0007093880.015
gene silencing by rnaGO:0031047570.014
mitotic cell cycle phase transitionGO:00447721380.014
adult behaviorGO:00305341370.014
Fly
positive regulation of cellular protein metabolic processGO:00322701180.014
Mouse
regulation of transforming growth factor beta receptor signaling pathwayGO:001701560.014
production of molecular mediator of immune responseGO:0002440460.014
single organism membrane organizationGO:0044802930.014
mesenchymal cell developmentGO:001403110.014
Mouse
immune responseGO:00069552460.014
regulation of apoptotic processGO:00429811300.014
positive regulation of phosphate metabolic processGO:00459371390.014
Mouse
appendage developmentGO:00487364010.014
cellular response to organic cyclic compoundGO:0071407320.014
regulation of phosphorylationGO:00423251470.014
Mouse
molting cycle chitin based cuticleGO:0007591560.013
cellular response to nitrogen compoundGO:1901699510.013
regulation of protein stabilityGO:0031647430.013
defense response to gram negative bacteriumGO:0050829940.013
positive regulation of proteolysisGO:0045862520.013
cell cycle checkpointGO:0000075950.013
regulation of cellular amine metabolic processGO:003323830.013
cellular nitrogen compound catabolic processGO:00442701650.013
regulation of vesicle mediated transportGO:0060627590.013
chromatin modificationGO:00165681470.013
negative regulation of signalingGO:00230572190.013
regulation of programmed cell deathGO:00430671520.013
cellular response to abiotic stimulusGO:0071214580.013
peptidyl threonine modificationGO:001821030.013
cellular response to lipidGO:0071396200.013
secretion by cellGO:00329401010.013
mitotic g2 dna damage checkpointGO:0007095690.013
humoral immune responseGO:00069591170.013
posttranscriptional gene silencing by rnaGO:0035194450.013
peptidyl amino acid modificationGO:00181931050.013
Mouse
nephron developmentGO:007200630.013
Mouse
regulation of hydrolase activityGO:0051336970.013
positive regulation of intracellular transportGO:0032388420.013
positive regulation of phosphorylationGO:0042327870.012
Mouse
spindle organizationGO:00070512530.012
stem cell proliferationGO:0072089880.012
Fly
positive regulation of transportGO:0051050920.012
defense responseGO:00069523000.012
cellular macromolecular complex assemblyGO:00346221530.012
dorsal ventral pattern formation imaginal discGO:0007450510.012
Fly
growthGO:00400073590.012
generation of precursor metabolites and energyGO:0006091420.012
small molecule biosynthetic processGO:0044283370.012
salivary gland morphogenesisGO:00074351450.012
positive regulation of cell migrationGO:003033520.012
regulation of cellular component biogenesisGO:00440872010.012
positive regulation of apoptotic processGO:0043065470.012
response to external biotic stimulusGO:00432072930.012
response to decreased oxygen levelsGO:0036293580.012
positive regulation of molecular functionGO:00440931360.012
Mouse
mapk cascadeGO:00001651070.012
antimicrobial humoral responseGO:0019730990.012
regulation of cell cycle phase transitionGO:19019871300.012
membrane organizationGO:00610241120.012
anterior posterior pattern specificationGO:00099521360.012
Zebrafish Mouse Worm
renal tubule developmentGO:0061326640.012
Mouse
mrna 3 end processingGO:0031124280.012
imaginal disc derived appendage developmentGO:00487373990.012
regulation of nuclear divisionGO:0051783580.012
Fly
negative regulation of immune responseGO:0050777390.012
imaginal disc derived wing morphogenesisGO:00074763370.011
rna processingGO:00063961470.011
regulation of innate immune responseGO:0045088710.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
negative regulation of multicellular organismal processGO:00512411420.011
Human Zebrafish Mouse
negative regulation of cell cycle phase transitionGO:19019881030.011
gene silencing by mirnaGO:0035195220.011
regulation of steroid metabolic processGO:001921820.011
cell cycle phase transitionGO:00447701400.011
protein import into nucleusGO:0006606510.011
Mouse
negative regulation of intracellular signal transductionGO:1902532570.011
imaginal disc derived wing vein morphogenesisGO:0008586440.011
regulation of defense responseGO:00313471020.011
protein phosphorylationGO:00064681690.011
Mouse
homeostatic processGO:00425921990.011
epidermis developmentGO:0008544650.011
Mouse Worm
tyrosine phosphorylation of stat proteinGO:000726010.011
Mouse
regulation of protein complex assemblyGO:0043254420.011
regulation of nucleocytoplasmic transportGO:0046822350.010
protein targetingGO:0006605640.010
Mouse
positive regulation of cellular catabolic processGO:0031331950.010
single organism membrane fusionGO:0044801420.010
regulation of mrna metabolic processGO:1903311720.010
circadian rhythmGO:00076231050.010
positive regulation of developmental processGO:00510941430.010
Mouse Fly
nucleoside phosphate metabolic processGO:00067531620.010

h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.014