Drosophila melanogaster

72 known processes

eIF4G (Dmel_CG10811)

eukaryotic translation initiation factor 4G

(Aliases: p200,deIF4G,Dmel\CG10811,eIF-4G,CG10811,Eif4G,eIF4g)

eIF4G biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of gene expressionGO:00106293870.423
catabolic processGO:00090564090.355
locomotory behaviorGO:00076261760.231
biological adhesionGO:00226101380.213
vesicle mediated transportGO:00161923810.195
organic cyclic compound catabolic processGO:19013611680.193
homeostatic processGO:00425921990.161
translationGO:0006412690.157
nuclear divisionGO:00002803320.155
organophosphate metabolic processGO:00196371950.150
nucleobase containing compound catabolic processGO:00346551650.146
anion transmembrane transportGO:0098656260.143
rna catabolic processGO:0006401370.129
organelle fissionGO:00482853400.123
regulation of multicellular organism growthGO:0040014400.120
golgi to plasma membrane transportGO:000689380.116
body morphogenesisGO:001017120.110
dna damage checkpointGO:0000077780.108
response to biotic stimulusGO:00096072940.107
cell migrationGO:00164772380.093
organic substance catabolic processGO:19015753080.093
intracellular transportGO:00469072280.093
ion transmembrane transportGO:00342201220.092
regulation of translationGO:0006417560.090
positive regulation of nucleobase containing compound metabolic processGO:00459353320.085
regulation of localizationGO:00328792750.082
multicellular organism growthGO:0035264460.079
cellular response to dna damage stimulusGO:00069742230.077
cell cycle phase transitionGO:00447701400.076
cellular macromolecule catabolic processGO:00442651360.072
establishment of protein localization to membraneGO:0090150110.071
purine nucleoside metabolic processGO:00422781270.067
regulation of growthGO:00400082330.065
meiotic cell cycleGO:00513211710.065
negative regulation of cellular biosynthetic processGO:00313272770.064
positive regulation of cellular component biogenesisGO:0044089800.064
nucleoside metabolic processGO:00091161270.063
negative regulation of macromolecule biosynthetic processGO:00105582700.063
mrna metabolic processGO:00160711240.062
endomembrane system organizationGO:00102561190.062
response to organic substanceGO:00100332840.061
cellular nitrogen compound catabolic processGO:00442701650.059
programmed cell deathGO:00125012570.059
microtubule organizing center organizationGO:00310231680.058
telencephalon developmentGO:002153720.058
transmembrane transportGO:00550851390.055
drug transmembrane transportGO:000685520.054
heterocycle catabolic processGO:00467001660.054
macromolecular complex assemblyGO:00650032560.054
macromolecule catabolic processGO:00090571610.054
organic substance transportGO:00717022570.053
regulation of mitotic cell cycleGO:00073461900.053
protein importGO:0017038550.053
mitotic spindle elongationGO:0000022810.052
cellular homeostasisGO:0019725800.048
single organism membrane fusionGO:0044801420.048
negative regulation of biosynthetic processGO:00098902770.047
nucleocytoplasmic transportGO:0006913720.047
cell motilityGO:00488702510.047
regulation of cell cycle processGO:00105641810.047
nucleoside phosphate metabolic processGO:00067531620.047
plasma membrane organizationGO:0007009260.046
developmental growthGO:00485892800.045
regulation of tube diameterGO:0035296140.044
regulation of transcription from rna polymerase ii promoterGO:00063573780.044
response to endogenous stimulusGO:00097191190.044
regulation of protein complex assemblyGO:0043254420.043
regulation of cellular localizationGO:00603411360.042
negative regulation of cellular metabolic processGO:00313243820.042
regulation of erbb signaling pathwayGO:1901184420.042
cell adhesionGO:00071551360.041
cellular macromolecule localizationGO:00707272200.041
positive regulation of biosynthetic processGO:00098913160.041
positive regulation of multicellular organism growthGO:0040018210.041
protein localizationGO:00081042840.041
cellular component assembly involved in morphogenesisGO:00109271510.040
reproductive structure developmentGO:0048608740.040
protein transportGO:00150311550.040
single organism cellular localizationGO:19025801800.040
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.040
purine nucleotide catabolic processGO:00061951090.040
centrosome cycleGO:00070981370.039
nuclear transportGO:0051169720.039
compound eye developmentGO:00487493070.039
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.038
cellular response to chemical stimulusGO:00708871990.038
anterior posterior axis specificationGO:00099481090.038
response to organonitrogen compoundGO:0010243750.038
cell deathGO:00082192790.037
organelle fusionGO:0048284460.037
regulation of protein metabolic processGO:00512462560.037
mrna catabolic processGO:0006402330.037
hindbrain developmentGO:003090220.036
nucleobase containing small molecule metabolic processGO:00550861740.036
cellular response to hormone stimulusGO:0032870440.035
membrane organizationGO:00610241120.035
cell cycle checkpointGO:0000075950.034
multi organism behaviorGO:00517051750.034
positive regulation of cell migrationGO:003033520.034
single organism catabolic processGO:00447122280.034
blastoderm segmentationGO:00073501590.034
response to oxygen containing compoundGO:19017002000.033
growthGO:00400073590.033
central nervous system developmentGO:00074172010.033
response to metal ionGO:0010038230.032
cytoplasmic transportGO:00164821300.032
maternal determination of anterior posterior axis embryoGO:0008358740.032
establishment of protein localizationGO:00451841630.032
regulation of protein transportGO:0051223570.032
protein complex biogenesisGO:00702712010.032
organelle assemblyGO:00709251980.032
cellular catabolic processGO:00442483720.031
single organism behaviorGO:00447083910.031
response to drugGO:0042493170.031
forebrain developmentGO:003090020.031
posttranscriptional regulation of gene expressionGO:00106081450.030
response to hormoneGO:0009725450.030
embryonic pattern specificationGO:00098801740.030
positive regulation of macromolecule metabolic processGO:00106044050.030
cellular protein localizationGO:00346131600.030
enzyme linked receptor protein signaling pathwayGO:00071671790.029
response to peptideGO:1901652290.029
multi organism reproductive behaviorGO:00447051210.029
multicellular organismal reproductive behaviorGO:00330571100.029
negative regulation of cellular protein metabolic processGO:0032269850.028
axis specificationGO:00097981670.028
regulation of apoptotic processGO:00429811300.028
neurological system processGO:00508773580.028
rna localizationGO:00064031150.028
mitotic spindle organizationGO:00070522200.028
tripartite regional subdivisionGO:00073511030.028
positive regulation of cell motilityGO:200014730.028
carboxylic acid metabolic processGO:0019752920.028
establishment of localization in cellGO:00516494020.028
cellularizationGO:0007349900.027
dna metabolic processGO:00062592270.027
endocytosisGO:00068973100.027
adult behaviorGO:00305341370.027
protein targetingGO:0006605640.027
regulation of anatomical structure sizeGO:00900661630.027
intracellular protein transportGO:00068861040.027
innate immune responseGO:00450871440.026
cellular amino acid metabolic processGO:0006520610.026
regulation of immune system processGO:00026821760.026
centrosome organizationGO:00512971630.026
organophosphate catabolic processGO:00464341120.026
regulation of organelle organizationGO:00330431960.026
intracellular mrna localizationGO:0008298660.026
response to organic cyclic compoundGO:0014070890.026
positive regulation of rna biosynthetic processGO:19026802660.025
negative regulation of nitrogen compound metabolic processGO:00511722650.025
cellular protein modification processGO:00064644380.025
purine ribonucleoside catabolic processGO:00461301120.025
gtp catabolic processGO:0006184720.025
regulation of intracellular transportGO:0032386640.025
carbohydrate derivative metabolic processGO:19011352170.024
proteolysisGO:00065081920.024
protein modification processGO:00362114380.024
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
negative regulation of translationGO:0017148280.024
organonitrogen compound metabolic processGO:19015643180.024
regulation of cellular protein metabolic processGO:00322682430.023
single organism intracellular transportGO:19025822070.023
purine containing compound metabolic processGO:00725211550.023
deathGO:00162652840.023
cellular protein complex assemblyGO:0043623710.023
regulation of catabolic processGO:00098941700.023
regulation of transportGO:00510491810.023
oxoacid metabolic processGO:00434361030.023
ribonucleotide metabolic processGO:00092591450.022
spindle elongationGO:0051231830.022
regulation of cytoplasmic transportGO:1903649470.022
regulation of establishment of protein localizationGO:0070201610.022
immune system processGO:00023763470.022
purine ribonucleotide catabolic processGO:00091541090.022
positive regulation of signalingGO:00230562430.022
maintenance of locationGO:0051235730.022
oocyte differentiationGO:00099941450.022
purine ribonucleoside metabolic processGO:00461281270.022
regulation of nucleocytoplasmic transportGO:0046822350.021
regulation of vesicle mediated transportGO:0060627590.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
nephron tubule developmentGO:007208030.021
regulation of intracellular protein transportGO:0033157460.021
g2 dna damage checkpointGO:0031572690.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
ribonucleoside triphosphate catabolic processGO:00092031080.021
photoreceptor cell differentiationGO:00465301700.021
eye antennal disc developmentGO:0035214600.021
response to inorganic substanceGO:0010035440.020
regulation of proteolysisGO:0030162870.020
cell cycle arrestGO:000705040.020
nucleotide catabolic processGO:00091661090.020
positive regulation of nucleic acid templated transcriptionGO:19035082660.020
nucleotide metabolic processGO:00091171610.020
cilium morphogenesisGO:0060271390.020
histone modificationGO:00165701060.020
protein complex assemblyGO:00064612000.019
phagocytosisGO:00069092150.019
brain developmentGO:00074201200.019
cellular macromolecular complex assemblyGO:00346221530.019
response to lipopolysaccharideGO:003249640.019
ribonucleoprotein complex subunit organizationGO:0071826280.019
response to peptide hormoneGO:0043434290.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
regulation of programmed cell deathGO:00430671520.019
membrane fusionGO:0061025420.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
regulation of hydrolase activityGO:0051336970.019
regulation of cell cycle phase transitionGO:19019871300.018
positive regulation of catabolic processGO:00098961050.018
cell proliferationGO:00082832990.018
purine nucleoside catabolic processGO:00061521120.018
nuclear transcribed mrna catabolic processGO:0000956240.018
localization of cellGO:00516742570.018
cellular response to organic substanceGO:00713101320.018
nucleoside phosphate catabolic processGO:19012921100.018
nucleoside triphosphate catabolic processGO:00091431080.018
embryonic axis specificationGO:00005781070.018
positive regulation of gene expressionGO:00106282900.018
oocyte developmentGO:00485991240.018
glycosyl compound catabolic processGO:19016581120.018
organic acid metabolic processGO:00060821030.017
response to bacteriumGO:00096171980.017
cellular response to insulin stimulusGO:0032869280.017
response to hypoxiaGO:0001666530.017
regulation of protein catabolic processGO:0042176550.017
response to axon injuryGO:0048678120.017
anterior posterior pattern specificationGO:00099521360.017
dorsal ventral pattern formationGO:00099531330.017
multi multicellular organism processGO:00447061230.017
axonogenesisGO:00074092900.016
oocyte anterior posterior axis specificationGO:0007314720.016
positive regulation of response to stimulusGO:00485843230.016
regulation of cell deathGO:00109411730.016
oocyte constructionGO:00073081120.016
chemical homeostasisGO:0048878920.016
establishment of protein localization to plasma membraneGO:009000290.016
nuclear transcribed mrna catabolic process deadenylation dependent decayGO:0000288140.016
ribonucleoside catabolic processGO:00424541120.016
regulation of microtubule cytoskeleton organizationGO:0070507410.016
rna transportGO:0050658460.016
nucleoside triphosphate metabolic processGO:00091411200.016
segmentationGO:00352822070.016
cell recognitionGO:00080371020.016
ribonucleotide catabolic processGO:00092611090.016
agingGO:00075681430.016
inorganic ion transmembrane transportGO:0098660730.016
negative regulation of cell cycle processGO:00109481090.016
regulation of epithelial cell differentiationGO:003085640.016
purine ribonucleoside triphosphate catabolic processGO:00092071080.016
cell maturationGO:00484691440.016
posttranscriptional gene silencing by rnaGO:0035194450.016
protein modification by small protein conjugation or removalGO:00706471060.015
purine ribonucleotide metabolic processGO:00091501450.015
protein localization to organelleGO:0033365820.015
purine nucleoside monophosphate metabolic processGO:0009126500.015
small molecule metabolic processGO:00442813050.015
regulation of nuclear divisionGO:0051783580.015
purine nucleoside triphosphate metabolic processGO:00091441190.015
centrosome duplicationGO:00512981210.015
response to oxygen levelsGO:0070482590.015
cellular response to decreased oxygen levelsGO:0036294300.015
dna integrity checkpointGO:0031570810.015
response to abiotic stimulusGO:00096283410.015
chromosome organizationGO:00512763600.015
cholesterol homeostasisGO:004263230.015
regulation of protein localizationGO:0032880760.015
nephron tubule morphogenesisGO:007207830.015
response to organophosphorusGO:004668320.015
positive regulation of developmental growthGO:0048639620.015
intracellular signal transductionGO:00355563000.015
response to decreased oxygen levelsGO:0036293580.015
meiotic nuclear divisionGO:00071261510.014
positive regulation of cellular biosynthetic processGO:00313283160.014
male gamete generationGO:00482322010.014
oocyte axis specificationGO:00073091080.014
actin cytoskeleton organizationGO:00300362060.014
anterior posterior axis specification embryoGO:00085951030.014
response to woundingGO:0009611940.014
centriole replicationGO:0007099240.014
cellular response to peptide hormone stimulusGO:0071375280.014
positive regulation of transcription dna templatedGO:00458932660.014
response to nitrogen compoundGO:1901698900.014
regulation of developmental growthGO:00486381740.014
trna aminoacylationGO:004303920.014
positive regulation of catalytic activityGO:00430851180.014
eye morphogenesisGO:00485922600.014
response to extracellular stimulusGO:00099911160.014
compound eye morphogenesisGO:00017452490.013
insulin receptor signaling pathwayGO:0008286250.013
head developmentGO:00603221350.013
gene silencingGO:00164581380.013
regulation of cellular component biogenesisGO:00440872010.013
cell divisionGO:00513012480.013
cation transportGO:00068121100.013
aromatic compound catabolic processGO:00194391660.013
protein heterooligomerizationGO:005129140.013
negative regulation of cell cycleGO:00457861160.013
positive regulation of protein complex assemblyGO:0031334220.013
protein localization to nucleusGO:0034504550.013
cell cycle g1 s phase transitionGO:0044843310.013
cellular response to organonitrogen compoundGO:0071417360.013
development of primary sexual characteristicsGO:0045137500.013
maintenance of location in cellGO:0051651280.013
nucleoside catabolic processGO:00091641120.013
positive regulation of protein localization to plasma membraneGO:190307830.013
single organism membrane organizationGO:0044802930.012
molting cycle chitin based cuticleGO:0007591560.012
negative regulation of mitotic cell cycleGO:00459301090.012
positive regulation of establishment of protein localization to plasma membraneGO:009000430.012
mitotic dna integrity checkpointGO:0044774750.012
negative regulation of rna metabolic processGO:00512532510.012
connective tissue developmentGO:006144830.012
phosphorylationGO:00163102940.012
cellular response to nitrogen compoundGO:1901699510.012
chemosensory behaviorGO:00076351060.012
anatomical structure homeostasisGO:0060249970.012
spermatid differentiationGO:00485151140.012
lipid localizationGO:0010876540.011
regulation of gene expression epigeneticGO:00400291280.011
developmental maturationGO:00217001720.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
positive regulation of developmental processGO:00510941430.011
positive regulation of protein transportGO:0051222370.011
regulation of cell divisionGO:0051302720.011
negative regulation of transcription dna templatedGO:00458922370.011
spermatogenesisGO:00072832000.011
divalent inorganic cation homeostasisGO:0072507290.011
negative regulation of protein metabolic processGO:0051248850.011
gland developmentGO:00487321910.011
cellular response to endogenous stimulusGO:0071495800.011
nucleoside monophosphate metabolic processGO:0009123520.011
protein localization to membraneGO:0072657190.010
protein maturationGO:0051604710.010
positive regulation of intracellular transportGO:0032388420.010
translational initiationGO:0006413110.010
nuclear transcribed mrna poly a tail shorteningGO:0000289120.010
wound healingGO:0042060750.010
single organism biosynthetic processGO:00447112060.010
response to calcium ionGO:005159210.010

eIF4G disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.115
disease of metabolismDOID:001466700.024
nervous system diseaseDOID:86300.022
cardiovascular system diseaseDOID:128700.019
central nervous system diseaseDOID:33100.012