Drosophila melanogaster

0 known processes

mthl6 (Dmel_CG16992)

methuselah-like 6

(Aliases: CG16992,Dmel\CG16992,anon-WO0170980.127,anon-WO0170980.128)

mthl6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523000.121
immune system processGO:00023763470.092
response to external biotic stimulusGO:00432072930.065
response to other organismGO:00517072930.062
response to biotic stimulusGO:00096072940.058
immune responseGO:00069552460.057
defense response to other organismGO:00985422250.056
defense response to bacteriumGO:00427421780.049
regulation of immune system processGO:00026821760.045
vesicle mediated transportGO:00161923810.043
Fly
regionalizationGO:00030024160.041
response to abiotic stimulusGO:00096283410.041
Fly
cell proliferationGO:00082832990.041
endocytosisGO:00068973100.039
organonitrogen compound metabolic processGO:19015643180.039
appendage developmentGO:00487364010.039
Fly
response to bacteriumGO:00096171980.038
innate immune responseGO:00450871440.035
imaginal disc derived appendage morphogenesisGO:00351143950.034
Fly
humoral immune responseGO:00069591170.032
small molecule metabolic processGO:00442813050.032
imaginal disc derived appendage developmentGO:00487373990.032
Fly
post embryonic appendage morphogenesisGO:00351203850.032
Fly
regulation of multicellular organismal developmentGO:20000264140.031
protein modification processGO:00362114380.031
regulation of cell proliferationGO:00421271630.030
phagocytosisGO:00069092150.030
neurological system processGO:00508773580.030
single organism behaviorGO:00447083910.030
body morphogenesisGO:001017120.029
catabolic processGO:00090564090.029
taxisGO:00423303040.029
appendage morphogenesisGO:00351073970.029
Fly
cellular protein modification processGO:00064644380.029
response to organic substanceGO:00100332840.029
Fly
wing disc morphogenesisGO:00074723440.029
Fly
imaginal disc derived wing morphogenesisGO:00074763370.028
Fly
positive regulation of response to stimulusGO:00485843230.028
negative regulation of gene expressionGO:00106293870.028
cell deathGO:00082192790.027
establishment of localization in cellGO:00516494020.027
Fly
organic substance catabolic processGO:19015753080.026
organic substance transportGO:00717022570.026
camera type eye developmentGO:004301040.026
organelle fissionGO:00482853400.026
phosphorylationGO:00163102940.026
positive regulation of signal transductionGO:00099672230.026
positive regulation of nitrogen compound metabolic processGO:00511733540.025
forebrain developmentGO:003090020.025
positive regulation of cellular biosynthetic processGO:00313283160.025
positive regulation of signalingGO:00230562430.025
protein localizationGO:00081042840.025
sensory perception of chemical stimulusGO:00076061160.024
g protein coupled receptor signaling pathwayGO:00071861360.024
Fly
response to lipopolysaccharideGO:003249640.024
positive regulation of macromolecule metabolic processGO:00106044050.024
regulation of cellular amine metabolic processGO:003323830.024
intracellular signal transductionGO:00355563000.024
nuclear divisionGO:00002803320.024
kidney developmentGO:000182230.024
compound eye developmentGO:00487493070.024
cellular catabolic processGO:00442483720.024
positive regulation of biosynthetic processGO:00098913160.024
organic acid metabolic processGO:00060821030.024
regulation of localizationGO:00328792750.023
negative regulation of response to stimulusGO:00485852580.023
response to monosaccharideGO:003428440.023
regulation of cell cycleGO:00517262910.023
oxoacid metabolic processGO:00434361030.023
cellular amino acid metabolic processGO:0006520610.023
eye developmentGO:00016543230.023
positive regulation of cell communicationGO:00106472500.023
carboxylic acid metabolic processGO:0019752920.023
defense response to gram positive bacteriumGO:0050830410.023
response to oxygen containing compoundGO:19017002000.022
Fly
deathGO:00162652840.022
hormone catabolic processGO:004244730.022
detection of chemical stimulusGO:0009593930.022
negative regulation of signal transductionGO:00099682060.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
regulation of cellular ketone metabolic processGO:001056530.021
compound eye morphogenesisGO:00017452490.021
negative regulation of cellular metabolic processGO:00313243820.021
adult behaviorGO:00305341370.021
sensory perceptionGO:00076001960.021
connective tissue developmentGO:006144830.021
programmed cell deathGO:00125012570.020
cellular macromolecule localizationGO:00707272200.020
telencephalon developmentGO:002153720.020
regulation of intracellular signal transductionGO:19025312360.020
neuron projection guidanceGO:00974852410.020
actin filament based processGO:00300292200.020
Fly
regulation of cellular amino acid metabolic processGO:000652100.020
intracellular transportGO:00469072280.020
regulation of cell differentiationGO:00455953020.020
transcription from rna polymerase ii promoterGO:00063663680.020
response to organophosphorusGO:004668320.020
negative regulation of cell communicationGO:00106482230.020
xenobiotic catabolic processGO:004217810.020
single organism catabolic processGO:00447122280.020
negative regulation of signalingGO:00230572190.020
eye morphogenesisGO:00485922600.020
chromosome organizationGO:00512763600.020
steroid catabolic processGO:000670610.020
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.019
regulation of phosphorus metabolic processGO:00511742100.019
single organism intracellular transportGO:19025822070.019
regulation of response to stressGO:00801342000.019
single organism biosynthetic processGO:00447112060.019
positive regulation of nucleobase containing compound metabolic processGO:00459353320.019
regulation of cell developmentGO:00602842150.019
localization of cellGO:00516742570.019
regulation of cellular protein metabolic processGO:00322682430.019
actin cytoskeleton organizationGO:00300362060.019
positive regulation of cell migrationGO:003033520.019
sensory organ morphogenesisGO:00905962600.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
negative regulation of cellular biosynthetic processGO:00313272770.018
growthGO:00400073590.018
amine metabolic processGO:0009308120.018
regulation of multi organism processGO:00439001310.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
homeostatic processGO:00425921990.018
regulation of protein metabolic processGO:00512462560.018
ras protein signal transductionGO:0007265880.018
exocrine system developmentGO:00352721620.018
segmentationGO:00352822070.018
developmental growthGO:00485892800.018
immune response activating signal transductionGO:000275720.018
benzene containing compound metabolic processGO:004253730.018
negative regulation of macromolecule biosynthetic processGO:00105582700.018
salivary gland developmentGO:00074311620.018
sensory perception of smellGO:0007608800.018
chromatin organizationGO:00063252070.018
immune response regulating signaling pathwayGO:000276420.018
gland developmentGO:00487321910.018
gene silencingGO:00164581380.018
positive regulation of rna biosynthetic processGO:19026802660.018
macromolecular complex assemblyGO:00650032560.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
cellular amine metabolic processGO:0044106120.018
cellular ketone metabolic processGO:0042180240.018
response to glucoseGO:000974920.018
tube morphogenesisGO:00352391910.018
Fly
vitamin biosynthetic processGO:000911010.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
regulation of mitotic cell cycleGO:00073461900.018
cell divisionGO:00513012480.018
developmental maturationGO:00217001720.018
regulation of nervous system developmentGO:00519602480.018
positive regulation of gene expressionGO:00106282900.017
digestive tract developmentGO:00485651490.017
Fly
limb developmentGO:006017310.017
multi organism behaviorGO:00517051750.017
synaptic transmissionGO:00072682880.017
Fly
positive regulation of phosphorus metabolic processGO:00105621390.017
axonogenesisGO:00074092900.017
cellular response to dna damage stimulusGO:00069742230.017
chemotaxisGO:00069352490.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
carbohydrate derivative metabolic processGO:19011352170.017
transmembrane transportGO:00550851390.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
negative regulation of rna biosynthetic processGO:19026792400.017
detection of stimulusGO:00516061560.017
regulation of phosphate metabolic processGO:00192202100.017
regulation of cell cycle processGO:00105641810.017
blastoderm segmentationGO:00073501590.017
regulation of molecular functionGO:00650092170.017
organic cyclic compound catabolic processGO:19013611680.017
secondary metabolic processGO:0019748750.017
heterocycle catabolic processGO:00467001660.017
chemosensory behaviorGO:00076351060.017
response to woundingGO:0009611940.017
cellular response to chemical stimulusGO:00708871990.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
respiratory system developmentGO:00605412130.017
axon guidanceGO:00074112330.017
salivary gland morphogenesisGO:00074351450.017
positive regulation of cell motilityGO:200014730.017
tube developmentGO:00352952440.017
Fly
spindle organizationGO:00070512530.017
epithelial cell differentiationGO:00308553220.017
wound healingGO:0042060750.016
negative regulation of rna metabolic processGO:00512532510.016
embryonic pattern specificationGO:00098801740.016
regulation of anatomical structure morphogenesisGO:00226032420.016
response to radiationGO:00093141550.016
proteolysisGO:00065081920.016
nucleobase containing small molecule metabolic processGO:00550861740.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
regulation of transportGO:00510491810.016
regulation of catalytic activityGO:00507901850.016
response to hexoseGO:000974630.016
central nervous system developmentGO:00074172010.016
regulation of immune responseGO:00507761180.016
antimicrobial humoral responseGO:0019730990.016
negative regulation of transcription dna templatedGO:00458922370.016
hindbrain developmentGO:003090220.016
regulation of cellular component biogenesisGO:00440872010.016
cellular nitrogen compound catabolic processGO:00442701650.016
aromatic compound catabolic processGO:00194391660.016
ion transportGO:00068111450.016
organophosphate metabolic processGO:00196371950.016
cell motilityGO:00488702510.016
morphogenesis of an epitheliumGO:00020092760.016
response to nutrient levelsGO:00316671140.016
Fly
nucleotide metabolic processGO:00091171610.016
regulation of organelle organizationGO:00330431960.016
cellular protein localizationGO:00346131600.016
small gtpase mediated signal transductionGO:0007264880.016
regulation of anatomical structure sizeGO:00900661630.016
purine nucleotide metabolic processGO:00061631460.015
regulation of cell deathGO:00109411730.015
cellular response to ethanolGO:007136140.015
immune effector processGO:0002252980.015
nucleoside phosphate metabolic processGO:00067531620.015
negative regulation of immune system processGO:0002683500.015
establishment of protein localizationGO:00451841630.015
epithelial cell developmentGO:00020642740.015
protein transportGO:00150311550.015
regulation of epithelial cell proliferationGO:005067840.015
positive regulation of transcription dna templatedGO:00458932660.015
negative regulation of developmental processGO:00510932010.015
axis specificationGO:00097981670.015
open tracheal system developmentGO:00074242040.015
organelle assemblyGO:00709251980.015
protein phosphorylationGO:00064681690.015
columnar cuboidal epithelial cell differentiationGO:00020652560.015
purine ribonucleotide metabolic processGO:00091501450.015
peptide metabolic processGO:0006518800.015
androgen metabolic processGO:000820910.015
nucleobase containing compound catabolic processGO:00346551650.015
gland morphogenesisGO:00226121450.015
nephron developmentGO:007200630.015
regulation of i kappab kinase nf kappab signalingGO:004312220.015
mitotic nuclear divisionGO:00070672130.015
retina development in camera type eyeGO:006004140.015
estrogen metabolic processGO:000821010.015
cellular amide metabolic processGO:0043603800.015
regulation of cellular localizationGO:00603411360.015
activation of innate immune responseGO:000221840.015
negative regulation of biosynthetic processGO:00098902770.014
rna processingGO:00063961470.014
response to alcoholGO:0097305950.014
positive regulation of developmental processGO:00510941430.014
actin filament organizationGO:00070151260.014
melanization defense responseGO:0035006450.014
apoptotic processGO:00069151590.014
nephron epithelium developmentGO:007200930.014
developmental programmed cell deathGO:00106231380.014
anion homeostasisGO:005508130.014
defense response to gram negative bacteriumGO:0050829940.014
ovarian follicle cell developmentGO:00307072480.014
axon developmentGO:00615642970.014
ameboidal type cell migrationGO:00016671510.014
regulation of programmed cell deathGO:00430671520.014
kidney epithelium developmentGO:007207330.014
regulation of response to external stimulusGO:00321011150.014
regulation of cellular catabolic processGO:00313291570.014
multicellular organismal agingGO:00102591400.014
Fly
ribonucleotide metabolic processGO:00092591450.014
regulation of epithelial cell differentiationGO:003085640.014
dorsal ventral pattern formationGO:00099531330.014
digestive system developmentGO:00551231490.014
Fly
neuropeptide signaling pathwayGO:0007218450.014
lateral inhibitionGO:00463312060.014
organonitrogen compound biosynthetic processGO:19015661170.014
neuron recognitionGO:00080381010.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
neurotransmitter metabolic processGO:004213320.014
detection of chemical stimulus involved in sensory perceptionGO:0050907750.014
spermatogenesisGO:00072832000.014
determination of adult lifespanGO:00083401370.014
Fly
single organism cellular localizationGO:19025801800.014
cytoplasmic transportGO:00164821300.014
phenol containing compound metabolic processGO:0018958570.014
purine containing compound metabolic processGO:00725211550.014
cellular response to organic substanceGO:00713101320.014
melanin metabolic processGO:0006582470.014
regulation of developmental growthGO:00486381740.014
negative regulation of cell proliferationGO:0008285690.014
mesenchymal cell differentiationGO:004876210.014
agingGO:00075681430.014
Fly
camera type eye morphogenesisGO:004859320.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
chromatin modificationGO:00165681470.014
polyol biosynthetic processGO:004617330.013
regulation of gene expression epigeneticGO:00400291280.013
innate immune response activating signal transductionGO:000275820.013
vitamin metabolic processGO:000676620.013
nephron tubule developmentGO:007208030.013
cellular component assembly involved in morphogenesisGO:00109271510.013
l amino acid importGO:004309220.013
endomembrane system organizationGO:00102561190.013
leg disc developmentGO:0035218920.013
macromolecule catabolic processGO:00090571610.013
fat soluble vitamin metabolic processGO:000677510.013
intracellular protein transmembrane transportGO:006500240.013
protein complex biogenesisGO:00702712010.013
positive regulation of multicellular organismal processGO:00512401430.013
tissue migrationGO:00901301550.013
Fly
digestive tract morphogenesisGO:00485461270.013
Fly
ribose phosphate metabolic processGO:00196931450.013
tissue morphogenesisGO:00487292970.013
Fly
cellular response to molecule of bacterial originGO:007121930.013
positive regulation of phosphate metabolic processGO:00459371390.013
pattern recognition receptor signaling pathwayGO:000222120.013
oocyte differentiationGO:00099941450.013
pigment metabolic processGO:0042440840.013
regulation of defense responseGO:00313471020.013
regulation of notch signaling pathwayGO:00085931000.013
synapse assemblyGO:00074161430.013
positive regulation of intracellular signal transductionGO:19025331160.013
positive regulation of catabolic processGO:00098961050.013
dna metabolic processGO:00062592270.013
purine ribonucleoside metabolic processGO:00461281270.013
multicellular organismal reproductive behaviorGO:00330571100.013
negative regulation of cell differentiationGO:00455961430.013
cell recognitionGO:00080371020.013
regulation of phosphorylationGO:00423251470.013
locomotory behaviorGO:00076261760.013
response to light stimulusGO:00094161240.013
multi multicellular organism processGO:00447061230.013
positive regulation of cellular amine metabolic processGO:003324000.013
embryonic development via the syncytial blastodermGO:00017001480.013
mitotic spindle organizationGO:00070522200.013
sterol homeostasisGO:005509240.013
positive regulation of molecular functionGO:00440931360.013
regulation of apoptotic processGO:00429811300.013
positive regulation of rna metabolic processGO:00512542710.013
signal transduction by phosphorylationGO:00230141070.013
ribonucleoside metabolic processGO:00091191270.013
male gamete generationGO:00482322010.013
organonitrogen compound catabolic processGO:19015651280.013
notch signaling pathwayGO:00072191200.012
monocarboxylic acid transportGO:001571830.012
behavioral response to ethanolGO:0048149490.012
lipid metabolic processGO:00066291210.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
chromosome segregationGO:00070591570.012
male courtship behaviorGO:0008049630.012
anatomical structure homeostasisGO:0060249970.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
chemical homeostasisGO:0048878920.012
regulation of response to biotic stimulusGO:0002831630.012
mapk cascadeGO:00001651070.012
regulation of mapk cascadeGO:0043408920.012
kidney morphogenesisGO:006099330.012
cholesterol homeostasisGO:004263230.012
wnt signaling pathwayGO:0016055980.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
neutral lipid biosynthetic processGO:004646020.012
oocyte developmentGO:00485991240.012
mrna metabolic processGO:00160711240.012
organic hydroxy compound metabolic processGO:1901615830.012
chaeta developmentGO:0022416970.012
rna localizationGO:00064031150.012
regulation of catabolic processGO:00098941700.012
nitrogen compound transportGO:0071705850.012
photoreceptor cell differentiationGO:00465301700.012
dendrite morphogenesisGO:00488131990.012
ethanolamine containing compound metabolic processGO:004243940.012
eye photoreceptor cell differentiationGO:00017541450.012
posttranscriptional regulation of gene expressionGO:00106081450.012
negative regulation of cell cycle processGO:00109481090.012
negative regulation of multicellular organismal processGO:00512411420.012
anterior posterior pattern specificationGO:00099521360.012
positive regulation of catalytic activityGO:00430851180.012
embryonic morphogenesisGO:00485982060.012
Fly
somatic muscle developmentGO:0007525660.012
mesodermal cell migrationGO:000807870.012
spinal cord developmentGO:002151010.012
regulation of hydrolase activityGO:0051336970.012
regulation of mitotic cell cycle phase transitionGO:19019901300.012
glycosyl compound metabolic processGO:19016571270.012
response to extracellular stimulusGO:00099911160.012
Fly
intracellular protein transportGO:00068861040.012
anterior posterior axis specification embryoGO:00085951030.012
compound eye photoreceptor cell differentiationGO:00017511400.012
carbohydrate derivative catabolic processGO:19011361180.012
tripartite regional subdivisionGO:00073511030.012
cellular homeostasisGO:0019725800.012
cell maturationGO:00484691440.012
positive regulation of cellular catabolic processGO:0031331950.012
cellular macromolecule catabolic processGO:00442651360.012
meiotic cell cycleGO:00513211710.012
limb morphogenesisGO:003510810.012
response to heatGO:0009408630.012
Fly
hematopoietic progenitor cell differentiationGO:000224410.012
positive regulation of protein metabolic processGO:00512471280.012
cellular response to biotic stimulusGO:007121640.012
nucleoside triphosphate metabolic processGO:00091411200.012
salivary gland histolysisGO:0035070880.012
mitotic dna integrity checkpointGO:0044774750.012
protein complex assemblyGO:00064612000.012
cell cycle phase transitionGO:00447701400.011
negative regulation of cell cycleGO:00457861160.011
response to starvationGO:0042594970.011
Fly
cellular response to lipopolysaccharideGO:007122230.011
response to endogenous stimulusGO:00097191190.011
negative regulation of mitotic cell cycleGO:00459301090.011
purine nucleoside metabolic processGO:00422781270.011
protein heterooligomerizationGO:005129140.011
nucleoside phosphate catabolic processGO:19012921100.011
synapse organizationGO:00508081960.011
l glutamate importGO:005193810.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
cell cycle checkpointGO:0000075950.011
mitotic cell cycle phase transitionGO:00447721380.011
regulation of cellular amide metabolic processGO:0034248390.011
secretion by cellGO:00329401010.011
Fly
protein transmembrane transportGO:007180640.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
regulation of cell morphogenesisGO:00226041630.011
matingGO:00076181200.011
regulation of synapse structure and activityGO:00508031280.011
histolysisGO:00075591020.011
positive regulation of immune system processGO:0002684680.011
response to ethanolGO:0045471590.011
negative regulation of gene expression epigeneticGO:0045814770.011
secretionGO:00469031090.011
Fly
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
nucleoside catabolic processGO:00091641120.011
chromosome separationGO:0051304420.011
ribonucleoside catabolic processGO:00424541120.011
response to temperature stimulusGO:00092661060.011
Fly
dendrite developmentGO:00163582040.011
cuticle developmentGO:0042335860.011
lauric acid metabolic processGO:004825210.011
organelle localizationGO:00516401480.011
Fly
response to copper ionGO:004668840.011
courtship behaviorGO:0007619680.011
g2 dna damage checkpointGO:0031572690.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
nephron tubule morphogenesisGO:007207830.011
cell migrationGO:00164772380.011
nucleoside triphosphate catabolic processGO:00091431080.011
regulation of lipid transportGO:003236830.011
positive regulation of lipid storageGO:001088440.011
sensory perception of painGO:001923340.011
positive regulation of cellular component organizationGO:00511301560.011
ribonucleotide catabolic processGO:00092611090.011
negative regulation of nervous system developmentGO:0051961920.011
fat soluble vitamin biosynthetic processGO:004236210.011
cell fate determinationGO:0001709910.011
purine ribonucleoside catabolic processGO:00461301120.011
nephron epithelium morphogenesisGO:007208830.011
positive regulation of transportGO:0051050920.011
regulation of neurogenesisGO:00507671580.011
purine nucleoside catabolic processGO:00061521120.011
nucleoside metabolic processGO:00091161270.011
regulation of cell substrate adhesionGO:001081020.011
nephron morphogenesisGO:007202830.011
regulation of cellular response to stressGO:0080135890.011
multi organism reproductive behaviorGO:00447051210.011
autophagic cell deathGO:0048102830.011
peptidyl amino acid modificationGO:00181931050.011
head developmentGO:00603221350.011
regulation of cell cycle phase transitionGO:19019871300.011
molting cycle chitin based cuticleGO:0007591560.011
nucleotide catabolic processGO:00091661090.011
response to mercury ionGO:004668930.011
dorsal ventral axis specificationGO:0009950660.011
cellular response to carbohydrate stimulusGO:007132240.011
imaginal disc pattern formationGO:0007447910.011
drinking behaviorGO:004275620.011
mesenchymal cell developmentGO:001403110.011
mrna processingGO:00063971040.011
photoreceptor cell developmentGO:0042461960.011
anterior posterior axis specificationGO:00099481090.011
positive regulation of phosphorylationGO:0042327870.011
neural retina developmentGO:000340740.011
regulation of ras protein signal transductionGO:0046578930.011
mitotic cell cycle checkpointGO:0007093880.011
establishment or maintenance of cell polarityGO:00071631670.010

mthl6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.021
cardiovascular system diseaseDOID:128700.016
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.014
musculoskeletal system diseaseDOID:1700.012
artery diseaseDOID:005082800.012
vascular diseaseDOID:17800.012
sensory system diseaseDOID:005015500.012
disease of cellular proliferationDOID:1456600.012
hypertensionDOID:1076300.012
eye diseaseDOID:561400.011
eye and adnexa diseaseDOID:149200.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
central nervous system diseaseDOID:33100.011
essential hypertensionDOID:1082500.011
urinary system diseaseDOID:1800.011