Drosophila melanogaster

42 known processes

DNApol-alpha60 (Dmel_CG5553)

DNA polymerase alpha 60kD

(Aliases: Pol,Dmel\CG5553,S(faf)240,Dmpol alpha,DNAprimase,DNA polalpha,GM13640,DNAprim,CG5553,l(3)j10B2,pol alpha,BcDNA:GM13640,l(3)77ABe)

DNApol-alpha60 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organelle fissionGO:00482853400.588
nuclear divisionGO:00002803320.548
meiotic nuclear divisionGO:00071261510.524
dna replicationGO:0006260480.481
dna metabolic processGO:00062592270.342
negative regulation of cell cycle processGO:00109481090.342
chromosome segregationGO:00070591570.295
negative regulation of g2 m transition of mitotic cell cycleGO:001097280.292
nuclear dna replicationGO:003326010.284
negative regulation of cell cycleGO:00457861160.281
regulation of mitotic cell cycleGO:00073461900.272
cell cycle phase transitionGO:00447701400.271
negative regulation of mitotic cell cycle phase transitionGO:19019911030.269
dna replication initiationGO:000627060.260
mitotic nuclear divisionGO:00070672130.258
negative regulation of mitotic cell cycleGO:00459301090.256
regulation of cell cycle phase transitionGO:19019871300.244
regulation of cell cycle processGO:00105641810.208
meiotic cell cycle processGO:19030461320.205
regulation of mitotic cell cycle phase transitionGO:19019901300.185
mitotic sister chromatid separationGO:0051306300.185
eggshell chorion gene amplificationGO:000730790.185
negative regulation of cell cycle phase transitionGO:19019881030.184
regulation of mitosisGO:0007088560.180
mitotic cell cycle phase transitionGO:00447721380.178
compound eye developmentGO:00487493070.169
g2 m transition of mitotic cell cycleGO:0000086190.164
negative regulation of cell cycle g2 m phase transitionGO:190275080.164
tube morphogenesisGO:00352391910.145
female meiosis chromosome segregationGO:0016321330.138
mitotic dna integrity checkpointGO:0044774750.138
mitotic cell cycle checkpointGO:0007093880.136
cell cycle dna replicationGO:0044786230.132
regulation of mitotic sister chromatid separationGO:0010965280.131
male meiosisGO:0007140520.125
cystoblast divisionGO:0007282100.118
sister chromatid segregationGO:0000819920.115
dna amplificationGO:0006277110.112
cell cycle checkpointGO:0000075950.111
cellular protein modification processGO:00064644380.101
mitotic g2 m transition checkpointGO:0044818700.093
regulation of mitotic sister chromatid segregationGO:0033047280.091
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.086
intracellular signal transductionGO:00355563000.085
mitotic g2 dna damage checkpointGO:0007095690.084
body morphogenesisGO:001017120.084
regulation of cell cycleGO:00517262910.083
eggshell formationGO:00307031050.082
chromosome separationGO:0051304420.081
regulation of chromosome segregationGO:0051983320.080
dna dependent dna replicationGO:0006261170.079
negative regulation of chromosome segregationGO:0051985140.078
eye antennal disc developmentGO:0035214600.076
reciprocal meiotic recombinationGO:0007131190.074
epithelial cell differentiationGO:00308553220.074
dna integrity checkpointGO:0031570810.073
negative regulation of gene expressionGO:00106293870.072
appendage morphogenesisGO:00351073970.072
cell divisionGO:00513012480.072
post embryonic appendage morphogenesisGO:00351203850.070
regulation of cytoskeleton organizationGO:0051493890.070
appendage developmentGO:00487364010.067
ovarian follicle cell developmentGO:00307072480.066
protein modification processGO:00362114380.066
developmental growthGO:00485892800.064
metaphase anaphase transition of cell cycleGO:0044784280.064
negative regulation of nucleic acid templated transcriptionGO:19035072400.064
growthGO:00400073590.062
imaginal disc derived appendage developmentGO:00487373990.062
establishment of tissue polarityGO:0007164870.059
negative regulation of organelle organizationGO:0010639560.059
imaginal disc derived appendage morphogenesisGO:00351143950.057
mitotic sister chromatid segregationGO:0000070870.057
wing disc morphogenesisGO:00074723440.054
spindle assembly involved in mitosisGO:0090307500.053
regulation of nuclear divisionGO:0051783580.052
dna endoreduplicationGO:0042023220.051
ras protein signal transductionGO:0007265880.051
tissue morphogenesisGO:00487292970.050
regulation of cell divisionGO:0051302720.049
compound eye morphogenesisGO:00017452490.049
eye developmentGO:00016543230.049
female meiotic divisionGO:0007143700.048
cell proliferationGO:00082832990.048
leg disc morphogenesisGO:0007478800.047
columnar cuboidal epithelial cell differentiationGO:00020652560.046
regulation of cellular catabolic processGO:00313291570.045
sex differentiationGO:0007548810.045
regulation of cell proliferationGO:00421271630.044
g2 dna damage checkpointGO:0031572690.043
metaphase anaphase transition of mitotic cell cycleGO:0007091280.042
deathGO:00162652840.042
organelle localizationGO:00516401480.042
regulation of metaphase anaphase transition of cell cycleGO:1902099260.042
cellular response to dna damage stimulusGO:00069742230.041
regulation of sister chromatid cohesionGO:000706320.041
regulation of mitotic metaphase anaphase transitionGO:0030071260.040
cell cycle g2 m phase transitionGO:0044839220.040
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.040
spindle elongationGO:0051231830.040
protein modification by small protein conjugation or removalGO:00706471060.040
regulation of apoptotic processGO:00429811300.039
regulation of g2 m transition of mitotic cell cycleGO:0010389150.038
notch signaling pathwayGO:00072191200.038
eggshell chorion assemblyGO:0007306660.038
phagocytosisGO:00069092150.037
chorion containing eggshell formationGO:00073041050.037
mitotic dna damage checkpointGO:0044773740.036
embryo development ending in birth or egg hatchingGO:00097921520.036
positive regulation of signalingGO:00230562430.036
negative regulation of rna metabolic processGO:00512532510.035
regulation of organelle organizationGO:00330431960.035
determination of adult lifespanGO:00083401370.035
female germ line cyst formationGO:0048135420.034
single organism behaviorGO:00447083910.034
mitotic sister chromatid cohesionGO:000706460.034
segment specificationGO:0007379330.034
multicellular organismal agingGO:00102591400.034
negative regulation of cell deathGO:0060548810.033
respiratory system developmentGO:00605412130.033
germarium derived female germ line cyst formationGO:0030727420.033
positive regulation of cell communicationGO:00106472500.033
cellular catabolic processGO:00442483720.033
mitotic spindle elongationGO:0000022810.033
positive regulation of developmental growthGO:0048639620.032
meiosis iGO:0007127590.032
endomitotic cell cycleGO:000711370.031
regulation of growthGO:00400082330.031
response to biotic stimulusGO:00096072940.031
reciprocal dna recombinationGO:0035825190.030
regulation of protein depolymerizationGO:1901879270.030
centrosome cycleGO:00070981370.030
neurological system processGO:00508773580.030
open tracheal system developmentGO:00074242040.030
negative regulation of protein complex disassemblyGO:0043242230.030
cell type specific apoptotic processGO:0097285380.030
organelle fusionGO:0048284460.030
positive regulation of catabolic processGO:00098961050.029
regulation of nervous system developmentGO:00519602480.029
imaginal disc derived wing morphogenesisGO:00074763370.029
cell fate determinationGO:0001709910.029
chromosome condensationGO:0030261410.029
single organism biosynthetic processGO:00447112060.029
regulation of lipid kinase activityGO:004355020.028
regulation of phosphorus metabolic processGO:00511742100.028
heart developmentGO:0007507820.028
vesicle mediated transportGO:00161923810.028
establishment or maintenance of cell polarityGO:00071631670.028
axonogenesisGO:00074092900.027
dna replication checkpointGO:000007680.027
regulation of catabolic processGO:00098941700.027
pronuclear migrationGO:003504640.027
proteolysisGO:00065081920.027
spindle midzone assemblyGO:005125540.027
negative regulation of mitotic sister chromatid separationGO:2000816130.027
peripheral nervous system developmentGO:0007422520.026
positive regulation of signal transductionGO:00099672230.026
execution phase of apoptosisGO:009719470.026
positive regulation of mitotic cell cycle phase transitionGO:1901992200.025
epithelial cell developmentGO:00020642740.025
phosphorylationGO:00163102940.025
response to light stimulusGO:00094161240.025
organic substance transportGO:00717022570.025
mitotic chromosome condensationGO:0007076220.025
negative regulation of cellular metabolic processGO:00313243820.025
centrosome separationGO:0051299200.025
response to external biotic stimulusGO:00432072930.024
skin developmentGO:0043588650.024
spindle organizationGO:00070512530.024
regulation of response to stressGO:00801342000.024
negative regulation of macromolecule biosynthetic processGO:00105582700.024
positive regulation of mitotic sister chromatid separationGO:1901970100.023
mitotic spindle organizationGO:00070522200.023
positive regulation of response to stimulusGO:00485843230.023
digestive tract developmentGO:00485651490.023
cellular lipid metabolic processGO:0044255830.023
meiotic chromosome segregationGO:0045132590.022
positive regulation of purine nucleotide catabolic processGO:0033123460.022
forebrain developmentGO:003090020.022
purine nucleotide metabolic processGO:00061631460.021
regulation of protein complex disassemblyGO:0043244290.021
regulation of cell developmentGO:00602842150.021
regionalizationGO:00030024160.021
mesoderm developmentGO:0007498780.021
oocyte maturationGO:000155630.021
dna damage checkpointGO:0000077780.021
positive regulation of chromosome segregationGO:0051984100.021
modification dependent protein catabolic processGO:0019941780.021
cellular response to biotic stimulusGO:007121640.021
asymmetric protein localization involved in cell fate determinationGO:004516790.021
actin filament organizationGO:00070151260.021
guanosine containing compound metabolic processGO:1901068740.021
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.020
proteasomal protein catabolic processGO:0010498590.020
negative regulation of biosynthetic processGO:00098902770.020
positive regulation of cell proliferationGO:0008284470.020
negative regulation of programmed cell deathGO:0043069720.020
neuroblast proliferationGO:0007405740.020
cellular component assembly involved in morphogenesisGO:00109271510.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
larval developmentGO:00021641040.020
regulation of protein catabolic processGO:0042176550.020
digestive system developmentGO:00551231490.020
asymmetric cell divisionGO:0008356370.020
cilium assemblyGO:0042384380.020
spindle assemblyGO:0051225800.020
syncytial blastoderm mitotic cell cycleGO:0035186210.020
lateral inhibitionGO:00463312060.020
negative regulation of transcription dna templatedGO:00458922370.020
negative regulation of protein metabolic processGO:0051248850.020
regulation of cellular protein catabolic processGO:1903362440.020
cell cycle g1 s phase transitionGO:0044843310.019
gastrulation involving germ band extensionGO:0010004360.019
heterocycle catabolic processGO:00467001660.019
organic substance catabolic processGO:19015753080.019
positive regulation of developmental processGO:00510941430.019
response to extracellular stimulusGO:00099911160.019
meiotic cell cycleGO:00513211710.019
columnar cuboidal epithelial cell developmentGO:00020662490.019
regulation of sister chromatid segregationGO:0033045280.019
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.019
positive regulation of phosphorus metabolic processGO:00105621390.019
rho protein signal transductionGO:0007266140.018
protein phosphorylationGO:00064681690.018
chromosome organizationGO:00512763600.018
catabolic processGO:00090564090.018
regulation of developmental growthGO:00486381740.018
protein catabolic processGO:00301631010.018
telencephalon developmentGO:002153720.018
gastrulation with mouth forming firstGO:0001703360.018
regulation of heterochromatin assemblyGO:003144580.017
regulation of catalytic activityGO:00507901850.017
apoptotic processGO:00069151590.017
leg disc developmentGO:0035218920.017
locomotory behaviorGO:00076261760.017
establishment of localization in cellGO:00516494020.017
positive regulation of cellular catabolic processGO:0031331950.017
response to other organismGO:00517072930.017
dna biosynthetic processGO:0071897240.017
positive regulation of intracellular signal transductionGO:19025331160.017
wing disc pattern formationGO:0035222660.017
acylglycerol catabolic processGO:004646430.017
imaginal disc derived leg morphogenesisGO:0007480800.017
regulation of transcription from rna polymerase ii promoterGO:00063573780.017
mitotic cell cycle embryonicGO:0045448380.017
peptidyl amino acid modificationGO:00181931050.017
positive regulation of nucleoside metabolic processGO:0045979470.017
g1 s transition of mitotic cell cycleGO:0000082310.017
ubiquitin dependent protein catabolic processGO:0006511780.017
gliogenesisGO:0042063800.017
regulation of phosphorylationGO:00423251470.017
cellular response to sterol depletionGO:007150130.017
response to radiationGO:00093141550.016
non sensory hair organizationGO:0035316470.016
response to copper ionGO:004668840.016
organonitrogen compound metabolic processGO:19015643180.016
negative regulation of cytoskeleton organizationGO:0051494300.016
response to endoplasmic reticulum stressGO:0034976280.016
negative regulation of neural precursor cell proliferationGO:2000178270.016
negative regulation of microtubule depolymerizationGO:0007026210.016
positive regulation of growthGO:0045927750.016
distributive segregationGO:003283760.016
epidermal cell differentiationGO:0009913510.016
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.016
cilium organizationGO:0044782410.016
mrna metabolic processGO:00160711240.016
dna recombinationGO:0006310320.016
biological adhesionGO:00226101380.016
lipid localizationGO:0010876540.016
cellular ketone metabolic processGO:0042180240.016
agingGO:00075681430.015
negative regulation of cellular protein metabolic processGO:0032269850.015
negative regulation of mitotic sister chromatid segregationGO:0033048130.015
membrane organizationGO:00610241120.015
single organism cellular localizationGO:19025801800.015
endoplasmic reticulum organizationGO:0007029130.015
small gtpase mediated signal transductionGO:0007264880.015
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.015
signal transduction in response to dna damageGO:004277030.015
anterior posterior axis specificationGO:00099481090.015
negative regulation of cell proliferationGO:0008285690.015
eye photoreceptor cell fate commitmentGO:0042706370.015
negative regulation of neurogenesisGO:0050768530.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
microtubule cytoskeleton organization involved in mitosisGO:1902850520.015
mitotic spindle stabilizationGO:004314860.015
regulation of microtubule cytoskeleton organizationGO:0070507410.015
morphogenesis of an epitheliumGO:00020092760.015
oocyte differentiationGO:00099941450.015
negative regulation of nervous system developmentGO:0051961920.015
establishment of protein localizationGO:00451841630.015
protein ubiquitinationGO:0016567700.014
nucleotide metabolic processGO:00091171610.014
sensory organ precursor cell divisionGO:0045035100.014
dorsal ventral pattern formationGO:00099531330.014
epidermis developmentGO:0008544650.014
nucleus localizationGO:0051647340.014
regulation of meiosisGO:004002030.014
protein maturationGO:0051604710.014
regulation of intracellular signal transductionGO:19025312360.014
protein modification by small protein conjugationGO:0032446790.014
regulation of cell deathGO:00109411730.014
regulation of cellular response to stressGO:0080135890.014
response to organophosphorusGO:004668320.014
nucleobase containing small molecule metabolic processGO:00550861740.014
regulation of hydrolase activityGO:0051336970.014
neural retina developmentGO:000340740.014
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.014
spindle checkpointGO:0031577110.014
zymogen activationGO:0031638200.014
germarium derived egg chamber formationGO:00072931010.014
mitotic spindle assembly checkpointGO:0007094110.014
photoreceptor cell differentiationGO:00465301700.014
negative regulation of protein depolymerizationGO:1901880230.014
organ growthGO:0035265560.013
positive regulation of nucleotide metabolic processGO:0045981550.013
smoothened signaling pathwayGO:0007224490.013
organophosphate metabolic processGO:00196371950.013
regulation of cell morphogenesisGO:00226041630.013
organophosphate biosynthetic processGO:0090407460.013
purine containing compound metabolic processGO:00725211550.013
negative regulation of sister chromatid segregationGO:0033046130.013
organelle assemblyGO:00709251980.013
macromolecule catabolic processGO:00090571610.013
hair cell differentiationGO:0035315470.013
cell cycle comprising mitosis without cytokinesisGO:0033301250.013
glial cell differentiationGO:0010001350.013
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.013
development of primary sexual characteristicsGO:0045137500.012
regulation of microtubule depolymerizationGO:0031114240.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
regulation of programmed cell deathGO:00430671520.012
response to fungusGO:0009620500.012
protein hydroxylationGO:001812610.012
negative regulation of cellular component organizationGO:00511291080.012
neural precursor cell proliferationGO:0061351750.012
negative regulation of meiotic cell cycleGO:005144720.012
cell deathGO:00082192790.012
kidney developmentGO:000182230.012
transcription from rna polymerase ii promoterGO:00063663680.012
compound eye photoreceptor cell differentiationGO:00017511400.012
ion transportGO:00068111450.012
organic acid metabolic processGO:00060821030.012
regulation of anatomical structure sizeGO:00900661630.012
protein processingGO:0016485680.012
gene silencingGO:00164581380.012
meiotic cell cycle phase transitionGO:004477140.012
negative regulation of protein catabolic processGO:0042177170.012
modification dependent macromolecule catabolic processGO:0043632790.012
response to abiotic stimulusGO:00096283410.011
negative regulation of protein processingGO:0010955310.011
gonad developmentGO:0008406500.011
establishment of planar polarityGO:0001736870.011
programmed cell deathGO:00125012570.011
immune system processGO:00023763470.011
negative regulation of chromosome organizationGO:2001251190.011
positive regulation of phosphate metabolic processGO:00459371390.011
purine ribonucleotide catabolic processGO:00091541090.011
glycerolipid catabolic processGO:004650330.011
regulation of neural precursor cell proliferationGO:2000177350.011
negative regulation of cell developmentGO:0010721620.011
multicellular organism growthGO:0035264460.011
single organism intracellular transportGO:19025822070.011
microtubule organizing center organizationGO:00310231680.011
single organism membrane organizationGO:0044802930.011
immune responseGO:00069552460.011
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.011
protein complex biogenesisGO:00702712010.011
central nervous system developmentGO:00074172010.011
neuroblast fate determinationGO:0007400120.011
sensory perception of painGO:001923340.011
negative regulation of neuroblast proliferationGO:0007406270.011
negative regulation of cell divisionGO:0051782170.011
cell recognitionGO:00080371020.011
regulation of nucleotide catabolic processGO:0030811480.011
glial cell migrationGO:0008347310.011
protein transportGO:00150311550.011
germ line cyst formationGO:0048134440.011
reproductive system developmentGO:0061458740.011
negative regulation of nuclear divisionGO:0051784170.011
positive regulation of cell developmentGO:0010720610.011
cellular nitrogen compound catabolic processGO:00442701650.010
establishment of organelle localizationGO:00516561220.010
negative regulation of multicellular organismal processGO:00512411420.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
negative regulation of proteolysisGO:0045861310.010
sensory organ morphogenesisGO:00905962600.010
dna repairGO:0006281540.010
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.010
asymmetric protein localizationGO:0008105330.010
multi organism reproductive behaviorGO:00447051210.010
regulation of mitotic spindle organizationGO:006023690.010
nucleobase containing compound catabolic processGO:00346551650.010
imaginal disc pattern formationGO:0007447910.010
cytokinetic cell separationGO:000092010.010
positive regulation of r7 cell differentiationGO:004567870.010
lipid metabolic processGO:00066291210.010

DNApol-alpha60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.023
disease of metabolismDOID:001466700.023