Drosophila melanogaster

54 known processes

sdk (Dmel_CG5227)

sidekick

(Aliases: CT16627,Dmel\CG5227,BcDNA:LD22322,CG5227,BcDNA:RE63453,EG:BACR19J1.1)

sdk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
eye developmentGO:00016543230.770
eye morphogenesisGO:00485922600.725
negative regulation of erbb signaling pathwayGO:1901185290.689
regulation of erbb signaling pathwayGO:1901184420.605
epidermal growth factor receptor signaling pathwayGO:0007173580.555
ommatidial rotationGO:0016318200.546
erbb signaling pathwayGO:0038127580.431
protein modification processGO:00362114380.312
cellular protein modification processGO:00064644380.295
compound eye photoreceptor developmentGO:0042051780.286
morphogenesis of a polarized epitheliumGO:0001738930.281
brain developmentGO:00074201200.270
establishment or maintenance of cell polarityGO:00071631670.270
compound eye morphogenesisGO:00017452490.261
compound eye developmentGO:00487493070.251
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.222
macromolecular complex assemblyGO:00650032560.211
single organism cell adhesionGO:0098602470.205
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.186
eye photoreceptor cell differentiationGO:00017541450.173
establishment of tissue polarityGO:0007164870.163
imaginal disc derived appendage developmentGO:00487373990.162
sensory organ morphogenesisGO:00905962600.143
establishment of ommatidial planar polarityGO:0042067490.136
compound eye cone cell differentiationGO:0042675130.135
cell proliferationGO:00082832990.133
enzyme linked receptor protein signaling pathwayGO:00071671790.116
muscle attachmentGO:0016203360.116
single organismal cell cell adhesionGO:0016337450.114
establishment of planar polarityGO:0001736870.109
eye photoreceptor cell developmentGO:0042462810.108
negative regulation of signalingGO:00230572190.107
biological adhesionGO:00226101380.107
vesicle mediated transportGO:00161923810.103
compound eye photoreceptor cell differentiationGO:00017511400.102
programmed cell deathGO:00125012570.098
regionalizationGO:00030024160.093
cellular macromolecule localizationGO:00707272200.093
regulation of transportGO:00510491810.093
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.088
regulation of response to stressGO:00801342000.087
regulation of meiosisGO:004002030.084
photoreceptor cell developmentGO:0042461960.077
central nervous system developmentGO:00074172010.075
positive regulation of signalingGO:00230562430.074
cell adhesionGO:00071551360.072
regulation of photoreceptor cell differentiationGO:0046532340.071
positive regulation of macromolecule metabolic processGO:00106044050.071
organonitrogen compound metabolic processGO:19015643180.069
female meiotic divisionGO:0007143700.063
morphogenesis of an epitheliumGO:00020092760.062
regulation of developmental growthGO:00486381740.062
negative regulation of response to stimulusGO:00485852580.062
purine nucleotide metabolic processGO:00061631460.056
photoreceptor cell differentiationGO:00465301700.055
cell motilityGO:00488702510.054
regulation of protein metabolic processGO:00512462560.054
regulation of anatomical structure morphogenesisGO:00226032420.053
regulation of catalytic activityGO:00507901850.052
negative regulation of cell communicationGO:00106482230.052
homeostatic processGO:00425921990.049
protein localizationGO:00081042840.049
tube developmentGO:00352952440.048
taxisGO:00423303040.046
regulation of cellular component biogenesisGO:00440872010.046
intracellular mrna localizationGO:0008298660.046
r7 cell differentiationGO:0045466430.045
regulation of nervous system developmentGO:00519602480.045
regulation of organelle organizationGO:00330431960.043
axonogenesisGO:00074092900.042
ribonucleoside metabolic processGO:00091191270.042
covalent chromatin modificationGO:00165691060.042
chromatin organizationGO:00063252070.042
amine metabolic processGO:0009308120.040
protein complex biogenesisGO:00702712010.040
negative regulation of molecular functionGO:0044092510.040
regulation of axonogenesisGO:0050770320.040
axon developmentGO:00615642970.040
protein phosphorylationGO:00064681690.040
regulation of cell morphogenesisGO:00226041630.039
protein localization to nucleusGO:0034504550.039
organophosphate metabolic processGO:00196371950.037
response to abiotic stimulusGO:00096283410.036
multi organism behaviorGO:00517051750.035
protein modification by small protein conjugation or removalGO:00706471060.035
positive regulation of cell communicationGO:00106472500.034
small molecule metabolic processGO:00442813050.034
sensory perceptionGO:00076001960.034
cell deathGO:00082192790.033
regulation of r7 cell differentiationGO:0045676150.033
female meiosis chromosome segregationGO:0016321330.033
appendage developmentGO:00487364010.033
regulation of protein localizationGO:0032880760.033
stem cell fate commitmentGO:0048865250.033
regulation of cell shapeGO:00083601130.033
cellular amine metabolic processGO:0044106120.032
instar larval developmentGO:0002168550.030
regulation of molecular functionGO:00650092170.030
single organism cellular localizationGO:19025801800.030
meiotic cell cycleGO:00513211710.029
cellular response to dna damage stimulusGO:00069742230.029
purine nucleoside metabolic processGO:00422781270.029
regulation of transferase activityGO:0051338580.028
proteolysisGO:00065081920.028
organelle fissionGO:00482853400.028
water homeostasisGO:003010430.028
carboxylic acid metabolic processGO:0019752920.028
chemotaxisGO:00069352490.027
intracellular transportGO:00469072280.027
camera type eye developmentGO:004301040.027
meiotic cell cycle processGO:19030461320.027
ribonucleotide metabolic processGO:00092591450.027
heterocycle catabolic processGO:00467001660.026
carbohydrate derivative metabolic processGO:19011352170.026
purine nucleoside catabolic processGO:00061521120.026
regulation of establishment of protein localizationGO:0070201610.025
response to radiationGO:00093141550.025
histone modificationGO:00165701060.025
nuclear divisionGO:00002803320.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
response to light stimulusGO:00094161240.025
protein modification by small protein conjugationGO:0032446790.025
carbohydrate derivative catabolic processGO:19011361180.024
single organism behaviorGO:00447083910.024
positive regulation of molecular functionGO:00440931360.024
positive regulation of nucleobase containing compound metabolic processGO:00459353320.024
cellular protein localizationGO:00346131600.024
nucleoside metabolic processGO:00091161270.023
metal ion homeostasisGO:0055065440.023
negative regulation of transferase activityGO:0051348180.023
neurological system processGO:00508773580.023
positive regulation of transportGO:0051050920.023
regulation of intracellular transportGO:0032386640.023
positive regulation of response to stimulusGO:00485843230.023
chromatin modificationGO:00165681470.023
male gamete generationGO:00482322010.022
response to lipopolysaccharideGO:003249640.022
regulation of intracellular protein transportGO:0033157460.022
endocytosisGO:00068973100.022
spermatid developmentGO:0007286980.022
tissue morphogenesisGO:00487292970.022
purine ribonucleoside metabolic processGO:00461281270.022
negative regulation of cellular component organizationGO:00511291080.022
nucleoside phosphate metabolic processGO:00067531620.021
ovarian follicle cell developmentGO:00307072480.021
axis specificationGO:00097981670.021
protein ubiquitinationGO:0016567700.021
organic acid metabolic processGO:00060821030.021
oocyte differentiationGO:00099941450.020
purine ribonucleoside catabolic processGO:00461301120.020
hindbrain developmentGO:003090220.020
immune system processGO:00023763470.020
spermatid differentiationGO:00485151140.020
defense responseGO:00069523000.020
regulation of compound eye photoreceptor developmentGO:0045314120.020
regulation of protein transportGO:0051223570.020
regulation of notch signaling pathwayGO:00085931000.019
regulation of cytoplasmic transportGO:1903649470.019
regulation of nuclear divisionGO:0051783580.019
organic substance transportGO:00717022570.019
ethanolamine containing compound metabolic processGO:004243940.019
purine containing compound metabolic processGO:00725211550.019
posttranscriptional regulation of gene expressionGO:00106081450.019
cell cell signaling involved in cell fate commitmentGO:00451682100.019
deathGO:00162652840.019
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.019
cellular amino acid metabolic processGO:0006520610.018
nucleobase containing small molecule metabolic processGO:00550861740.018
spermatogenesisGO:00072832000.018
positive regulation of nucleotide catabolic processGO:0030813460.018
ribonucleoside catabolic processGO:00424541120.018
growthGO:00400073590.018
axonal defasciculationGO:0007414120.018
response to oxygen containing compoundGO:19017002000.018
positive regulation of jun kinase activityGO:004350740.018
regulation of cell cycleGO:00517262910.018
negative regulation of protein metabolic processGO:0051248850.018
protein localization to organelleGO:0033365820.017
secretionGO:00469031090.017
signal transduction by phosphorylationGO:00230141070.017
positive regulation of ion transmembrane transporter activityGO:003241440.017
positive regulation of r7 cell differentiationGO:004567870.017
maintenance of locationGO:0051235730.017
cellular response to chemical stimulusGO:00708871990.017
positive regulation of signal transductionGO:00099672230.017
regulation of phosphate metabolic processGO:00192202100.017
intracellular signal transductionGO:00355563000.017
open tracheal system developmentGO:00074242040.017
phagocytosisGO:00069092150.017
purine ribonucleotide metabolic processGO:00091501450.017
peptidyl amino acid modificationGO:00181931050.016
regulation of cell divisionGO:0051302720.016
head developmentGO:00603221350.016
regulation of localizationGO:00328792750.016
hemopoiesisGO:0030097460.016
regulation of i kappab kinase nf kappab signalingGO:004312220.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
regulation of organ morphogenesisGO:2000027780.016
forebrain developmentGO:003090020.016
ribonucleotide catabolic processGO:00092611090.016
cellular ketone metabolic processGO:0042180240.016
cell junction assemblyGO:0034329420.016
regulation of cellular response to stressGO:0080135890.016
regulation of peptidase activityGO:0052547390.016
post embryonic appendage morphogenesisGO:00351203850.015
respiratory system developmentGO:00605412130.015
protein alkylationGO:0008213430.015
pigmentationGO:0043473750.015
single organism biosynthetic processGO:00447112060.015
tube morphogenesisGO:00352391910.015
developmental growth involved in morphogenesisGO:0060560650.015
ion transportGO:00068111450.015
response to woundingGO:0009611940.015
wound healingGO:0042060750.014
wing disc morphogenesisGO:00074723440.014
cell divisionGO:00513012480.014
nucleoside catabolic processGO:00091641120.014
negative regulation of cellular protein metabolic processGO:0032269850.014
regulation of cell deathGO:00109411730.014
circulatory system processGO:0003013370.014
multi organism reproductive behaviorGO:00447051210.014
response to other organismGO:00517072930.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
notch signaling pathwayGO:00072191200.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
epithelial cell differentiationGO:00308553220.014
wnt signaling pathwayGO:0016055980.013
regulation of cellular amine metabolic processGO:003323830.013
negative regulation of phosphate metabolic processGO:0045936450.013
ras protein signal transductionGO:0007265880.013
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.013
endomembrane system organizationGO:00102561190.013
regulation of defense responseGO:00313471020.013
regulation of cellular protein metabolic processGO:00322682430.013
morphogenesis of embryonic epitheliumGO:0016331940.013
establishment of organelle localizationGO:00516561220.013
lateral inhibitionGO:00463312060.013
exocrine system developmentGO:00352721620.013
gene silencingGO:00164581380.013
positive regulation of intracellular signal transductionGO:19025331160.013
release of sequestered calcium ion into cytosolGO:005120910.013
catabolic processGO:00090564090.013
embryonic morphogenesisGO:00485982060.013
carbohydrate derivative biosynthetic processGO:1901137850.013
ribonucleoside monophosphate metabolic processGO:0009161510.013
epithelial cell developmentGO:00020642740.013
single organism catabolic processGO:00447122280.012
protein complex assemblyGO:00064612000.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
negative regulation of catalytic activityGO:0043086420.012
negative regulation of cell deathGO:0060548810.012
immune effector processGO:0002252980.012
imaginal disc derived wing morphogenesisGO:00074763370.012
localization of cellGO:00516742570.012
ribose phosphate metabolic processGO:00196931450.012
regulation of cellular localizationGO:00603411360.012
positive regulation of catalytic activityGO:00430851180.012
matingGO:00076181200.012
nucleoside phosphate catabolic processGO:19012921100.012
guanosine containing compound metabolic processGO:1901068740.012
negative regulation of homeostatic processGO:003284520.012
regulation of apoptotic processGO:00429811300.012
regulation of protein kinase activityGO:0045859510.012
protein glycosylationGO:0006486320.012
learning or memoryGO:00076111410.012
glycoprotein metabolic processGO:0009100410.012
chromosome separationGO:0051304420.012
regulation of cell morphogenesis involved in differentiationGO:0010769610.012
oxoacid metabolic processGO:00434361030.012
somatic muscle developmentGO:0007525660.011
organonitrogen compound biosynthetic processGO:19015661170.011
imaginal disc derived wing vein specificationGO:0007474480.011
regulation of anatomical structure sizeGO:00900661630.011
purine containing compound catabolic processGO:00725231120.011
meiotic chromosome segregationGO:0045132590.011
regulation of cellular ketone metabolic processGO:001056530.011
cytoplasmic transportGO:00164821300.011
regulation of phosphorus metabolic processGO:00511742100.011
calcium ion transportGO:0006816240.011
phosphorylationGO:00163102940.011
negative regulation of multicellular organismal processGO:00512411420.011
compound eye cone cell fate commitmentGO:004267650.011
nucleobase containing compound catabolic processGO:00346551650.011
motor neuron axon guidanceGO:0008045580.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of protein modification processGO:00313991120.011
regulation of phosphatase activityGO:001092130.011
posttranscriptional gene silencingGO:0016441460.011
macromolecule methylationGO:0043414450.011
positive regulation of phosphate metabolic processGO:00459371390.011
glycosyl compound metabolic processGO:19016571270.011
establishment of localization in cellGO:00516494020.011
regulation of mapk cascadeGO:0043408920.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
homophilic cell adhesion via plasma membrane adhesion moleculesGO:0007156180.010
organelle localizationGO:00516401480.010
negative regulation of erk1 and erk2 cascadeGO:007037330.010
positive regulation of biosynthetic processGO:00098913160.010
positive regulation of i kappab kinase nf kappab signalingGO:004312310.010
rho protein signal transductionGO:0007266140.010
regulation of embryonic cell shapeGO:0016476300.010
negative regulation of organelle organizationGO:0010639560.010
nucleoside triphosphate catabolic processGO:00091431080.010

sdk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.016
urinary system diseaseDOID:1800.015
organ system cancerDOID:005068600.014