IMP: Integrative Multi-species Prediction

Drosophila melanogaster

206 known processes

nej (Dmel_CG15319)

nejire

(Aliases: anon-WO03040301.89,l(1)G0350,l(1)G0112,Nej,p300,Dmel\CG15319,Dmel_CG15321,CBP_,l(1)G0470,CBP,Crbp,p300/CBP,Cbp,dmCBP,nej CBP,dCBP,CG15319,CG15321,anon-WO0147981.11,cbp,CBP/p300)

Entrez: 43856
FLYBASE: FBgn0261617
UniProtKB: M9PH39
UniProtKB: M9MS40
UniProtKB: Q9W321

Process Predictions
Disease Predictions

nej biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
programmed cell death	GO:0012501	257	0.999
death	GO:0016265	284	0.999
cell death	GO:0008219	279	0.999
regulation of cell death	GO:0010941	173	0.999
regulation of apoptotic process	GO:0042981	130	0.998
regulation of cell development	GO:0060284	215	0.998
growth	GO:0040007	359	0.997
apoptotic process	GO:0006915	159	0.995
dna metabolic process	GO:0006259	227	0.994
regulation of cell proliferation	GO:0042127	163	0.993
regulation of programmed cell death	GO:0043067	152	0.988
negative regulation of cell death	GO:0060548	81	0.981
organelle fission	GO:0048285	340	0.981
eye development	GO:0001654	323	0.979
signal release	GO:0023061	49	0.976
cellular protein modification process	GO:0006464	438	0.972
eye photoreceptor cell differentiation	GO:0001754	145	0.968
regulation of cell differentiation	GO:0045595	302	0.966
compound eye photoreceptor development	GO:0042051	78	0.966
negative regulation of gene expression	GO:0010629	387	0.966
gland development	GO:0048732	191	0.961
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.952
tube development	GO:0035295	244	0.951
negative regulation of programmed cell death	GO:0043069	72	0.951
regulation of protein metabolic process	GO:0051246	256	0.950
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.949
chromosome segregation	GO:0007059	157	0.943
secretion by cell	GO:0032940	101	0.938
post embryonic appendage morphogenesis	GO:0035120	385	0.938
learning or memory	GO:0007611	141	0.936
male gamete generation	GO:0048232	201	0.933
regulation of multicellular organismal development	GO:2000026	414	0.932
nuclear division	GO:0000280	332	0.932
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.931
negative regulation of developmental process	GO:0051093	201	0.931
meiotic cell cycle	GO:0051321	171	0.927
regionalization	GO:0003002	416	0.915
response to nutrient levels	GO:0031667	114	0.910
cell proliferation	GO:0008283	299	0.909
respiratory system development	GO:0060541	213	0.906
positive regulation of programmed cell death	GO:0043068	62	0.902
negative regulation of apoptotic process	GO:0043066	63	0.883
positive regulation of macromolecule metabolic process	GO:0010604	405	0.880
positive regulation of cell proliferation	GO:0008284	47	0.874
muscle tissue development	GO:0060537	30	0.873
tube morphogenesis	GO:0035239	191	0.868
central nervous system development	GO:0007417	201	0.866
regulation of neural precursor cell proliferation	GO:2000177	35	0.865
photoreceptor cell development	GO:0042461	96	0.864
dna packaging	GO:0006323	91	0.857
sensory organ morphogenesis	GO:0090596	260	0.856
negative regulation of cellular metabolic process	GO:0031324	382	0.843
positive regulation of transcription dna templated	GO:0045893	266	0.842
positive regulation of cell death	GO:0010942	69	0.838
phosphorylation	GO:0016310	294	0.833
brain development	GO:0007420	120	0.832
spermatogenesis	GO:0007283	200	0.819
regulation of neurogenesis	GO:0050767	158	0.818
compound eye morphogenesis	GO:0001745	249	0.817
meiosis i	GO:0007127	59	0.809
regulation of cellular protein metabolic process	GO:0032268	243	0.801
regulation of cell shape	GO:0008360	113	0.801
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.800
epithelial tube morphogenesis	GO:0060562	88	0.797
segmentation	GO:0035282	207	0.787
organ growth	GO:0035265	56	0.785
regulation of phosphorus metabolic process	GO:0051174	210	0.783
cellular response to chemical stimulus	GO:0070887	199	0.782
proteolysis	GO:0006508	192	0.769
regulation of proteolysis	GO:0030162	87	0.764
eye photoreceptor cell development	GO:0042462	81	0.764
negative regulation of multicellular organismal process	GO:0051241	142	0.763
r3 r4 cell differentiation	GO:0048056	12	0.761
response to sterol	GO:0036314	34	0.757
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.757
covalent chromatin modification	GO:0016569	106	0.750
meiotic chromosome segregation	GO:0045132	59	0.749
regulation of cellular catabolic process	GO:0031329	157	0.740
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.738
regulation of cell cycle	GO:0051726	291	0.733
regulation of organ growth	GO:0046620	42	0.733
branching involved in open tracheal system development	GO:0060446	45	0.722
negative regulation of response to stimulus	GO:0048585	258	0.722
eye morphogenesis	GO:0048592	260	0.714
cellular response to organic substance	GO:0071310	132	0.711
developmental growth	GO:0048589	280	0.709
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.707
response to endogenous stimulus	GO:0009719	119	0.705
mitotic cell cycle embryonic	GO:0045448	38	0.705
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.705
forebrain development	GO:0030900	2	0.705
negative regulation of cell communication	GO:0010648	223	0.692
regulation of proteasomal protein catabolic process	GO:0061136	39	0.683
r7 cell differentiation	GO:0045466	43	0.679
regulation of nervous system development	GO:0051960	248	0.679
chromosome organization	GO:0051276	360	0.673
blastoderm segmentation	GO:0007350	159	0.671
salivary gland development	GO:0007431	162	0.668
digestive system development	GO:0055123	149	0.663
positive regulation of reproductive process	GO:2000243	7	0.655
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.646
positive regulation of gene expression	GO:0010628	290	0.641
regulation of molecular function	GO:0065009	217	0.626
cellular response to dna damage stimulus	GO:0006974	223	0.625
chromatin organization	GO:0006325	207	0.623
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.621
negative regulation of biosynthetic process	GO:0009890	277	0.609
establishment of planar polarity	GO:0001736	87	0.602
developmental programmed cell death	GO:0010623	138	0.598
head development	GO:0060322	135	0.593
response to abiotic stimulus	GO:0009628	341	0.590
organic substance catabolic process	GO:1901575	308	0.574
periodic partitioning	GO:0007365	29	0.569
regulation of cellular localization	GO:0060341	136	0.567
negative regulation of cell proliferation	GO:0008285	69	0.567
digestive tract morphogenesis	GO:0048546	127	0.567
positive regulation of rna biosynthetic process	GO:1902680	266	0.566
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.565
mitotic cell cycle phase transition	GO:0044772	138	0.564
positive regulation of multicellular organismal process	GO:0051240	143	0.559
histolysis	GO:0007559	102	0.557
regulation of stem cell proliferation	GO:0072091	40	0.552
intracellular signal transduction	GO:0035556	300	0.551
notch signaling pathway	GO:0007219	120	0.541
positive regulation of cellular biosynthetic process	GO:0031328	316	0.540
tissue morphogenesis	GO:0048729	297	0.538
gene silencing	GO:0016458	138	0.529
positive regulation of cell development	GO:0010720	61	0.525
regulation of chromosome organization	GO:0033044	64	0.518
negative regulation of cellular biosynthetic process	GO:0031327	277	0.515
imaginal disc derived appendage development	GO:0048737	399	0.514
positive regulation of cellular protein metabolic process	GO:0032270	118	0.505
regulation of phosphorylation	GO:0042325	147	0.503
positive regulation of r7 cell differentiation	GO:0045678	7	0.503
transcription from rna polymerase ii promoter	GO:0006366	368	0.497
catabolic process	GO:0009056	409	0.497
negative regulation of signaling	GO:0023057	219	0.496
positive regulation of biosynthetic process	GO:0009891	316	0.494
regulation of catabolic process	GO:0009894	170	0.493
positive regulation of rna metabolic process	GO:0051254	271	0.490
multicellular organism growth	GO:0035264	46	0.488
cell type specific apoptotic process	GO:0097285	38	0.484
nucleosome organization	GO:0034728	59	0.479
segment polarity determination	GO:0007367	25	0.479
vesicle mediated transport	GO:0016192	381	0.475
regulation of cellular protein catabolic process	GO:1903362	44	0.473
proteasomal protein catabolic process	GO:0010498	59	0.453
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.453
centrosome organization	GO:0051297	163	0.447
neural precursor cell proliferation	GO:0061351	75	0.443
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.441
negative regulation of neurogenesis	GO:0050768	53	0.439
cellular protein catabolic process	GO:0044257	83	0.434
muscle structure development	GO:0061061	224	0.433
meiotic cell cycle process	GO:1903046	132	0.432
cell adhesion	GO:0007155	136	0.431
positive regulation of neurogenesis	GO:0050769	41	0.430
regulation of secretion	GO:0051046	44	0.425
protein modification process	GO:0036211	438	0.420
regulation of photoreceptor cell differentiation	GO:0046532	34	0.417
response to wounding	GO:0009611	94	0.416
embryonic pattern specification	GO:0009880	174	0.414
regulation of chromosome segregation	GO:0051983	32	0.413
response to organic substance	GO:0010033	284	0.413
negative regulation of cell development	GO:0010721	62	0.412
multi multicellular organism process	GO:0044706	123	0.409
cell cycle phase transition	GO:0044770	140	0.406
heart development	GO:0007507	82	0.400
heart morphogenesis	GO:0003007	32	0.395
regulation of cell growth	GO:0001558	43	0.394
positive regulation of mitotic cell cycle phase transition	GO:1901992	20	0.389
photoreceptor cell differentiation	GO:0046530	170	0.383
morphogenesis of an epithelium	GO:0002009	276	0.378
autophagy	GO:0006914	108	0.375
appendage development	GO:0048736	401	0.375
myotube differentiation	GO:0014902	46	0.375
positive regulation of nervous system development	GO:0051962	69	0.374
morphogenesis of a polarized epithelium	GO:0001738	93	0.369
dendrite morphogenesis	GO:0048813	199	0.364
dendrite development	GO:0016358	204	0.364
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.358
dna conformation change	GO:0071103	105	0.354
regulation of cell cycle phase transition	GO:1901987	130	0.352
cilium assembly	GO:0042384	38	0.346
neurological system process	GO:0050877	358	0.344
dorsal ventral pattern formation	GO:0009953	133	0.342
gliogenesis	GO:0042063	80	0.339
regulation of anatomical structure size	GO:0090066	163	0.339
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.338
response to oxygen containing compound	GO:1901700	200	0.337
regulation of tube size open tracheal system	GO:0035151	43	0.333
positive regulation of apoptotic process	GO:0043065	47	0.333
striated muscle cell differentiation	GO:0051146	90	0.329
regulation of organelle organization	GO:0033043	196	0.328
negative regulation of gene expression epigenetic	GO:0045814	77	0.323
single organism biosynthetic process	GO:0044711	206	0.320
secretion	GO:0046903	109	0.314
modification dependent protein catabolic process	GO:0019941	78	0.306
regulation of protein kinase activity	GO:0045859	51	0.299
cellular catabolic process	GO:0044248	372	0.298
regulation of secretion by cell	GO:1903530	39	0.298
multicellular organismal aging	GO:0010259	140	0.297
regulation of catalytic activity	GO:0050790	185	0.295
establishment or maintenance of cell polarity	GO:0007163	167	0.287
fusion cell fate specification	GO:0035156	4	0.285
striated muscle tissue development	GO:0014706	27	0.281
negative regulation of rna biosynthetic process	GO:1902679	240	0.280
protein catabolic process	GO:0030163	101	0.278
dna replication	GO:0006260	48	0.278
cell projection assembly	GO:0030031	94	0.273
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.269
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.269
regulation of neuroblast proliferation	GO:1902692	34	0.264
regulation of cellular ketone metabolic process	GO:0010565	3	0.262
positive regulation of molecular function	GO:0044093	136	0.257
establishment of tissue polarity	GO:0007164	87	0.255
negative regulation of meiotic cell cycle	GO:0051447	2	0.253
response to lipid	GO:0033993	38	0.251
r3 r4 cell fate commitment	GO:0007464	10	0.250
open tracheal system development	GO:0007424	204	0.250
regulation of developmental growth	GO:0048638	174	0.247
imaginal disc growth	GO:0007446	37	0.247
appendage morphogenesis	GO:0035107	397	0.240
muscle cell differentiation	GO:0042692	103	0.240
positive regulation of proteolysis	GO:0045862	52	0.233
regulation of embryonic development	GO:0045995	68	0.229
regulation of compound eye photoreceptor development	GO:0045314	12	0.229
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.227
positive regulation of photoreceptor cell differentiation	GO:0046534	12	0.226
cell growth	GO:0016049	108	0.223
carboxylic acid metabolic process	GO:0019752	92	0.221
histone modification	GO:0016570	106	0.221
regulation of dna metabolic process	GO:0051052	34	0.220
regulation of localization	GO:0032879	275	0.219
negative regulation of transcription dna templated	GO:0045892	237	0.212
morphogenesis of a branching structure	GO:0001763	45	0.210
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.209
cellular response to oxygen containing compound	GO:1901701	79	0.208
response to ecdysone	GO:0035075	34	0.205
cuticle development	GO:0042335	86	0.204
cell division	GO:0051301	248	0.203
wing disc pattern formation	GO:0035222	66	0.201
cellular response to endogenous stimulus	GO:0071495	80	0.200
positive regulation of protein modification process	GO:0031401	58	0.197
tissue death	GO:0016271	102	0.192
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.192
reproductive behavior	GO:0019098	122	0.191
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.190
meiotic nuclear division	GO:0007126	151	0.185
developmental pigmentation	GO:0048066	68	0.185
digestive tract development	GO:0048565	149	0.182
organelle assembly	GO:0070925	198	0.181
germ line cyst formation	GO:0048134	44	0.180
phenol containing compound metabolic process	GO:0018958	57	0.178
regulation of growth	GO:0040008	233	0.174
dna endoreduplication	GO:0042023	22	0.173
establishment of localization in cell	GO:0051649	402	0.170
cellular macromolecule catabolic process	GO:0044265	136	0.168
regulation of cell cycle process	GO:0010564	181	0.157
protein complex assembly	GO:0006461	200	0.156
cell fate specification	GO:0001708	71	0.156
spermatid development	GO:0007286	98	0.154
single organismal cell cell adhesion	GO:0016337	45	0.151
regulation of protein modification process	GO:0031399	112	0.150
telencephalon development	GO:0021537	2	0.150
apoptotic signaling pathway	GO:0097190	27	0.150
response to alcohol	GO:0097305	95	0.149
developmental maturation	GO:0021700	172	0.148
cell cycle dna replication	GO:0044786	23	0.146
regulation of cellular component biogenesis	GO:0044087	201	0.146
wound healing	GO:0042060	75	0.141
cellular component assembly involved in morphogenesis	GO:0010927	151	0.141
positive regulation of developmental process	GO:0051094	143	0.140
cell cycle g1 s phase transition	GO:0044843	31	0.139
response to organonitrogen compound	GO:0010243	75	0.139
response to ketone	GO:1901654	34	0.138
regulation of mitotic cell cycle	GO:0007346	190	0.133
single organism behavior	GO:0044708	391	0.133
regulation of mitotic cell cycle embryonic	GO:0009794	11	0.130
regulation of intracellular signal transduction	GO:1902531	236	0.129
regulation of gene expression epigenetic	GO:0040029	128	0.128
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.127
negative regulation of signal transduction	GO:0009968	206	0.124
nephrocyte diaphragm assembly	GO:0036059	3	0.124
regulation of transport	GO:0051049	181	0.124
negative regulation of rna metabolic process	GO:0051253	251	0.123
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.123
regulation of eye photoreceptor cell development	GO:0042478	13	0.121
epidermis morphogenesis	GO:0048730	5	0.119
posttranscriptional regulation of gene expression	GO:0010608	145	0.119
cellular response to external stimulus	GO:0071496	66	0.118
regulation of imaginal disc growth	GO:0045570	26	0.117
compound eye photoreceptor fate commitment	GO:0001752	36	0.117
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.116
regulation of dna replication	GO:0006275	13	0.116
axis specification	GO:0009798	167	0.116
negative regulation of cellular catabolic process	GO:0031330	34	0.115
regulation of response to stress	GO:0080134	200	0.113
protein phosphorylation	GO:0006468	169	0.113
response to hormone	GO:0009725	45	0.112
hindgut development	GO:0061525	58	0.111
cellular response to extracellular stimulus	GO:0031668	64	0.111
positive regulation of protein metabolic process	GO:0051247	128	0.111
positive regulation of cell cycle	GO:0045787	43	0.110
regulation of neuron differentiation	GO:0045664	103	0.110
organic substance transport	GO:0071702	257	0.110
regulation of cell size	GO:0008361	63	0.109
cellular response to nitrogen compound	GO:1901699	51	0.109
macromolecule catabolic process	GO:0009057	161	0.109
syncytium formation by plasma membrane fusion	GO:0000768	43	0.107
eggshell chorion assembly	GO:0007306	66	0.107
cellular amine metabolic process	GO:0044106	12	0.107
cardiac cell fate commitment	GO:0060911	17	0.107
chromatin modification	GO:0016568	147	0.107
hindbrain development	GO:0030902	2	0.106
locomotory behavior	GO:0007626	176	0.104
regulation of sister chromatid cohesion	GO:0007063	2	0.104
regulation of kinase activity	GO:0043549	53	0.103
spindle organization	GO:0007051	253	0.103
salivary gland cell autophagic cell death	GO:0035071	83	0.103
imaginal disc eversion	GO:0007561	4	0.102
regulation of cellular amino acid metabolic process	GO:0006521	0	0.102
amine metabolic process	GO:0009308	12	0.102
positive regulation of phosphorus metabolic process	GO:0010562	139	0.102
cognition	GO:0050890	141	0.100
positive regulation of cell differentiation	GO:0045597	64	0.100
regulation of execution phase of apoptosis	GO:1900117	5	0.097
glial cell differentiation	GO:0010001	35	0.097
organic acid metabolic process	GO:0006082	103	0.097
morphogenesis of a branching epithelium	GO:0061138	45	0.093
chromatin assembly	GO:0031497	48	0.091
modification dependent macromolecule catabolic process	GO:0043632	79	0.091
regulation of glial cell differentiation	GO:0045685	1	0.091
apoptotic process involved in development	GO:1902742	20	0.089
negative regulation of cell differentiation	GO:0045596	143	0.088
regulation of phosphate metabolic process	GO:0019220	210	0.087
dna integrity checkpoint	GO:0031570	81	0.086
pigmentation	GO:0043473	75	0.085
negative regulation of phosphate metabolic process	GO:0045936	45	0.084
protein modification by small protein conjugation	GO:0032446	79	0.084
imaginal disc derived wing morphogenesis	GO:0007476	337	0.083
immune response	GO:0006955	246	0.083
synaptic transmission	GO:0007268	288	0.083
regulation of gene silencing	GO:0060968	63	0.082
negative regulation of wnt signaling pathway	GO:0030178	28	0.081
cellular nitrogen compound catabolic process	GO:0044270	165	0.081
skin development	GO:0043588	65	0.080
regulation of wnt signaling pathway	GO:0030111	68	0.080
sex differentiation	GO:0007548	81	0.079
protein complex biogenesis	GO:0070271	201	0.078
cell cycle g2 m phase transition	GO:0044839	22	0.076
positive regulation of developmental growth	GO:0048639	62	0.075
organ formation	GO:0048645	39	0.075
positive regulation of cell cycle process	GO:0090068	28	0.073
response to peptide hormone	GO:0043434	29	0.073
regulation of protein localization	GO:0032880	76	0.072
negative regulation of organ growth	GO:0046621	15	0.072
imaginal disc pattern formation	GO:0007447	91	0.071
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.069
regulation of cell fate specification	GO:0042659	27	0.069
muscle tissue morphogenesis	GO:0060415	2	0.068
anterior posterior pattern specification	GO:0009952	136	0.068
tripartite regional subdivision	GO:0007351	103	0.068
positive regulation of mitotic cell cycle	GO:0045931	34	0.067
exocrine system development	GO:0035272	162	0.066
glial cell fate determination	GO:0007403	3	0.066
negative regulation of cell fate specification	GO:0009996	15	0.066
muscle organ development	GO:0007517	127	0.065
epithelial cell type specification open tracheal system	GO:0035153	11	0.064
g2 m transition of mitotic cell cycle	GO:0000086	19	0.064
cellular response to growth factor stimulus	GO:0071363	30	0.063
salivary gland histolysis	GO:0035070	88	0.063
stem cell proliferation	GO:0072089	88	0.063
intracellular steroid hormone receptor signaling pathway	GO:0030518	12	0.062
positive regulation of gtp catabolic process	GO:0033126	43	0.062
biological adhesion	GO:0022610	138	0.061
negative regulation of neural precursor cell proliferation	GO:2000178	27	0.061
ras protein signal transduction	GO:0007265	88	0.060
circulatory system development	GO:0072359	82	0.060
localization of cell	GO:0051674	257	0.060
wnt signaling pathway	GO:0016055	98	0.060
single organism catabolic process	GO:0044712	228	0.060
cell cycle arrest	GO:0007050	4	0.059
positive regulation of phosphorylation	GO:0042327	87	0.059
regulation of tube size	GO:0035150	46	0.059
negative regulation of cell cycle	GO:0045786	116	0.059
cell fate determination	GO:0001709	91	0.058
nucleobase containing compound catabolic process	GO:0034655	165	0.058
negative regulation of catalytic activity	GO:0043086	42	0.058
regulation of transferase activity	GO:0051338	58	0.058
larval development	GO:0002164	104	0.057
regulation of protein catabolic process	GO:0042176	55	0.057
hippo signaling	GO:0035329	20	0.057
cellular response to nutrient levels	GO:0031669	62	0.057
reactive oxygen species metabolic process	GO:0072593	22	0.056
regulation of cell division	GO:0051302	72	0.056
positive regulation of catabolic process	GO:0009896	105	0.056
mitotic sister chromatid separation	GO:0051306	30	0.056
anterior posterior axis specification embryo	GO:0008595	103	0.056
protein maturation	GO:0051604	71	0.056
regulation of malpighian tubule diameter	GO:0035297	3	0.056
establishment of organelle localization	GO:0051656	122	0.056
trachea morphogenesis	GO:0060439	22	0.055
gland morphogenesis	GO:0022612	145	0.055
protein dna complex subunit organization	GO:0071824	86	0.055
regulation of reactive oxygen species metabolic process	GO:2000377	8	0.055
regulation of epithelial cell proliferation	GO:0050678	4	0.055
germarium derived egg chamber formation	GO:0007293	101	0.054
positive regulation of proteasomal protein catabolic process	GO:1901800	20	0.053
positive regulation of catalytic activity	GO:0043085	118	0.053
positive regulation of transport	GO:0051050	92	0.052
negative regulation of notch signaling pathway	GO:0045746	41	0.052
multicellular organismal reproductive behavior	GO:0033057	110	0.051
carbohydrate homeostasis	GO:0033500	12	0.051
imaginal disc derived leg morphogenesis	GO:0007480	80	0.051
canonical wnt signaling pathway involved in heart development	GO:0061316	3	0.050
positive regulation of cellular amine metabolic process	GO:0033240	0	0.050
nucleosome assembly	GO:0006334	35	0.050
negative regulation of nervous system development	GO:0051961	92	0.050
reproductive system development	GO:0061458	74	0.049
gonad development	GO:0008406	50	0.049
negative regulation of intracellular signal transduction	GO:1902532	57	0.049
stem cell maintenance	GO:0019827	67	0.048
response to peptide	GO:1901652	29	0.048
body morphogenesis	GO:0010171	2	0.048
ecdysone mediated induction of salivary gland cell autophagic cell death	GO:0035072	12	0.048
immune system process	GO:0002376	347	0.048
oocyte differentiation	GO:0009994	145	0.048
embryonic organ development	GO:0048568	50	0.047
regulation of establishment of protein localization	GO:0070201	61	0.047
regulation of organ morphogenesis	GO:2000027	78	0.046
regulation of cytoskeleton organization	GO:0051493	89	0.046
negative regulation of cell cycle g1 s phase transition	GO:1902807	13	0.046
leg disc morphogenesis	GO:0007478	80	0.046
nucleoside triphosphate catabolic process	GO:0009143	108	0.045
positive regulation of organ growth	GO:0046622	12	0.045
transforming growth factor beta receptor signaling pathway	GO:0007179	16	0.045
protein modification by small protein conjugation or removal	GO:0070647	106	0.045
defense response	GO:0006952	300	0.044
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.044
regulation of binding	GO:0051098	16	0.044
mitotic spindle organization	GO:0007052	220	0.044
germ cell migration	GO:0008354	43	0.044
cellular amino acid metabolic process	GO:0006520	61	0.044
cell aging	GO:0007569	2	0.044
compound eye development	GO:0048749	307	0.043
regulation of response to nutrient levels	GO:0032107	18	0.043
regulation of cellular amine metabolic process	GO:0033238	3	0.043
negative regulation of heart induction	GO:1901320	3	0.042
leg disc development	GO:0035218	92	0.042
negative regulation of dendrite morphogenesis	GO:0050774	2	0.042
regulation of mitotic sister chromatid separation	GO:0010965	28	0.041
autophagic cell death	GO:0048102	83	0.041
photoreceptor cell fate commitment	GO:0046552	41	0.040
lipid metabolic process	GO:0006629	121	0.040
endocytosis	GO:0006897	310	0.040
axon guidance	GO:0007411	233	0.040
epithelial cell proliferation	GO:0050673	15	0.040
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	GO:1902254	1	0.040
hormone transport	GO:0009914	7	0.039
compound eye photoreceptor cell differentiation	GO:0001751	140	0.039
regulation of notch signaling pathway	GO:0008593	100	0.039
instar larval development	GO:0002168	55	0.039
negative regulation of molecular function	GO:0044092	51	0.038
molting cycle chitin based cuticle	GO:0007591	56	0.038
positive regulation of cellular catabolic process	GO:0031331	95	0.038
regulation of phosphatase activity	GO:0010921	3	0.037
negative regulation of heart induction by canonical wnt signaling pathway	GO:0003136	3	0.037
gene silencing by rna	GO:0031047	57	0.037
regulation of erbb signaling pathway	GO:1901184	42	0.037
chromatin silencing	GO:0006342	76	0.037
canonical wnt signaling pathway	GO:0060070	21	0.036
blood circulation	GO:0008015	26	0.036
regeneration	GO:0031099	16	0.035
cellular ketone metabolic process	GO:0042180	24	0.035
positive regulation of protein kinase activity	GO:0045860	25	0.035
intracellular receptor signaling pathway	GO:0030522	19	0.035
establishment or maintenance of polarity of larval imaginal disc epithelium	GO:0016336	3	0.035
regulation of apoptotic signaling pathway	GO:2001233	10	0.034
gonad morphogenesis	GO:0035262	7	0.034
reproductive structure development	GO:0048608	74	0.034
positive regulation of growth	GO:0045927	75	0.034
cilium organization	GO:0044782	41	0.034
regulation of immune system process	GO:0002682	176	0.034
branching morphogenesis of an epithelial tube	GO:0048754	45	0.033
protein localization	GO:0008104	284	0.033
positive regulation of cell cycle phase transition	GO:1901989	20	0.033
gtp catabolic process	GO:0006184	72	0.033
cellular lipid metabolic process	GO:0044255	83	0.033
cellular response to lipid	GO:0071396	20	0.033
regulation of hormone levels	GO:0010817	40	0.033
response to starvation	GO:0042594	97	0.032
oxoacid metabolic process	GO:0043436	103	0.032
neurotransmitter secretion	GO:0007269	35	0.032
positive regulation of secretion	GO:0051047	22	0.032
camera type eye development	GO:0043010	4	0.032
phagocytosis	GO:0006909	215	0.032

nej disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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