Drosophila melanogaster

29 known processes

HPS1 (Dmel_CG12855)

Hermansky-Pudlak Syndrome 1 ortholog

(Aliases: CG12855,Dmel\CG12855,HPS,dHPS1)

HPS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
small molecule metabolic processGO:00442813050.072
organonitrogen compound metabolic processGO:19015643180.061
appendage developmentGO:00487364010.057
imaginal disc derived wing morphogenesisGO:00074763370.051
post embryonic appendage morphogenesisGO:00351203850.051
wing disc morphogenesisGO:00074723440.049
imaginal disc derived appendage morphogenesisGO:00351143950.045
oxoacid metabolic processGO:00434361030.043
positive regulation of response to stimulusGO:00485843230.039
appendage morphogenesisGO:00351073970.038
imaginal disc derived appendage developmentGO:00487373990.037
organophosphate metabolic processGO:00196371950.036
single organism catabolic processGO:00447122280.035
organic substance catabolic processGO:19015753080.033
catabolic processGO:00090564090.033
protein modification processGO:00362114380.032
organic acid metabolic processGO:00060821030.032
positive regulation of signalingGO:00230562430.030
cellular protein modification processGO:00064644380.030
cellular catabolic processGO:00442483720.029
regulation of cellular catabolic processGO:00313291570.029
positive regulation of nucleobase containing compound metabolic processGO:00459353320.029
endocytosisGO:00068973100.028
cellular amino acid metabolic processGO:0006520610.028
positive regulation of cell communicationGO:00106472500.027
positive regulation of signal transductionGO:00099672230.027
intracellular signal transductionGO:00355563000.027
carboxylic acid metabolic processGO:0019752920.026
positive regulation of nitrogen compound metabolic processGO:00511733540.026
single organism behaviorGO:00447083910.025
vesicle mediated transportGO:00161923810.024
establishment of localization in cellGO:00516494020.024
organelle assemblyGO:00709251980.024
positive regulation of biosynthetic processGO:00098913160.023
cellular response to chemical stimulusGO:00708871990.023
negative regulation of response to stimulusGO:00485852580.023
actin cytoskeleton organizationGO:00300362060.023
chemotaxisGO:00069352490.023
protein complex biogenesisGO:00702712010.022
cytokinesisGO:0000910900.022
single organism biosynthetic processGO:00447112060.022
cellular amine metabolic processGO:0044106120.021
response to organic substanceGO:00100332840.021
macromolecular complex assemblyGO:00650032560.021
salivary gland morphogenesisGO:00074351450.020
axon developmentGO:00615642970.020
programmed cell deathGO:00125012570.020
regulation of molecular functionGO:00650092170.020
developmental growthGO:00485892800.020
cell deathGO:00082192790.020
organic substance transportGO:00717022570.019
gland morphogenesisGO:00226121450.019
axon guidanceGO:00074112330.019
regulation of catabolic processGO:00098941700.019
endomembrane system organizationGO:00102561190.019
regulation of intracellular signal transductionGO:19025312360.019
regulation of cellular amine metabolic processGO:003323830.019
negative regulation of signal transductionGO:00099682060.019
taxisGO:00423303040.019
regulation of phosphorus metabolic processGO:00511742100.019
morphogenesis of an epitheliumGO:00020092760.018
regulation of cell cycleGO:00517262910.018
localization of cellGO:00516742570.018
deathGO:00162652840.018
phagocytosisGO:00069092150.018
positive regulation of cellular catabolic processGO:0031331950.018
compound eye morphogenesisGO:00017452490.018
phosphorylationGO:00163102940.018
neuron projection guidanceGO:00974852410.018
organic cyclic compound catabolic processGO:19013611680.018
ras protein signal transductionGO:0007265880.018
forebrain developmentGO:003090020.018
positive regulation of macromolecule biosynthetic processGO:00105572830.017
gland developmentGO:00487321910.017
regulation of organelle organizationGO:00330431960.017
amine metabolic processGO:0009308120.017
response to lipopolysaccharideGO:003249640.017
exocrine system developmentGO:00352721620.017
camera type eye developmentGO:004301040.017
protein modification by small protein conjugation or removalGO:00706471060.017
synaptic transmissionGO:00072682880.016
positive regulation of cell motilityGO:200014730.016
protein complex assemblyGO:00064612000.016
developmental programmed cell deathGO:00106231380.016
compound eye developmentGO:00487493070.016
positive regulation of macromolecule metabolic processGO:00106044050.016
actin filament based processGO:00300292200.016
positive regulation of cellular biosynthetic processGO:00313283160.016
single organism intracellular transportGO:19025822070.016
macromolecule catabolic processGO:00090571610.016
positive regulation of gene expressionGO:00106282900.016
cytoskeleton dependent cytokinesisGO:0061640810.016
cellular component assembly involved in morphogenesisGO:00109271510.016
immune responseGO:00069552460.016
nucleoside phosphate metabolic processGO:00067531620.016
regulation of catalytic activityGO:00507901850.016
ribose phosphate metabolic processGO:00196931450.016
positive regulation of transcription dna templatedGO:00458932660.016
ribonucleotide metabolic processGO:00092591450.016
regulation of localizationGO:00328792750.015
cell migrationGO:00164772380.015
regulation of cellular ketone metabolic processGO:001056530.015
transcription from rna polymerase ii promoterGO:00063663680.015
organophosphate catabolic processGO:00464341120.015
purine nucleotide metabolic processGO:00061631460.015
cellular ketone metabolic processGO:0042180240.015
response to oxygen containing compoundGO:19017002000.015
nucleotide metabolic processGO:00091171610.015
negative regulation of gene expressionGO:00106293870.015
regulation of phosphate metabolic processGO:00192202100.015
growthGO:00400073590.015
mitotic nuclear divisionGO:00070672130.015
cellular macromolecular complex assemblyGO:00346221530.015
negative regulation of signalingGO:00230572190.014
anion homeostasisGO:005508130.014
aromatic compound catabolic processGO:00194391660.014
cell projection assemblyGO:0030031940.014
negative regulation of cell communicationGO:00106482230.014
small gtpase mediated signal transductionGO:0007264880.014
positive regulation of phosphorus metabolic processGO:00105621390.014
protein localizationGO:00081042840.014
sensory perception of chemical stimulusGO:00076061160.014
regulation of response to stressGO:00801342000.014
axonogenesisGO:00074092900.014
cell motilityGO:00488702510.014
response to endogenous stimulusGO:00097191190.014
ethanolamine containing compound metabolic processGO:004243940.014
neurological system processGO:00508773580.014
photoreceptor cell differentiationGO:00465301700.014
carbohydrate derivative metabolic processGO:19011352170.014
cell divisionGO:00513012480.014
regulation of transcription from rna polymerase ii promoterGO:00063573780.014
positive regulation of rna biosynthetic processGO:19026802660.014
cellular nitrogen compound catabolic processGO:00442701650.014
mitotic cytokinesisGO:0000281500.014
membrane organizationGO:00610241120.013
anatomical structure homeostasisGO:0060249970.013
epithelial cell differentiationGO:00308553220.013
regulation of cellular component biogenesisGO:00440872010.013
purine nucleotide catabolic processGO:00061951090.013
actin filament organizationGO:00070151260.013
connective tissue developmentGO:006144830.013
ion transportGO:00068111450.013
regulation of anatomical structure morphogenesisGO:00226032420.013
single organism membrane organizationGO:0044802930.013
regulation of cellular amino acid metabolic processGO:000652100.013
body morphogenesisGO:001017120.013
nucleotide catabolic processGO:00091661090.013
purine nucleoside metabolic processGO:00422781270.013
kidney developmentGO:000182230.013
purine containing compound metabolic processGO:00725211550.013
lipid metabolic processGO:00066291210.013
positive regulation of cellular amine metabolic processGO:003324000.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
positive regulation of rna metabolic processGO:00512542710.013
organonitrogen compound biosynthetic processGO:19015661170.013
positive regulation of catalytic activityGO:00430851180.013
regulation of immune system processGO:00026821760.013
ribonucleoside metabolic processGO:00091191270.013
steroid catabolic processGO:000670610.012
negative regulation of rna metabolic processGO:00512532510.012
positive regulation of molecular functionGO:00440931360.012
autophagic cell deathGO:0048102830.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
guanosine containing compound catabolic processGO:1901069740.012
agingGO:00075681430.012
regionalizationGO:00030024160.012
cellular response to organic substanceGO:00713101320.012
telencephalon developmentGO:002153720.012
response to abiotic stimulusGO:00096283410.012
regulation of protein metabolic processGO:00512462560.012
regulation of apoptotic processGO:00429811300.012
salivary gland developmentGO:00074311620.012
sterol homeostasisGO:005509240.012
protein phosphorylationGO:00064681690.012
cellular lipid metabolic processGO:0044255830.012
cell proliferationGO:00082832990.012
heterocycle catabolic processGO:00467001660.012
organonitrogen compound catabolic processGO:19015651280.012
regulation of cellular protein metabolic processGO:00322682430.012
response to organonitrogen compoundGO:0010243750.012
regulation of cellular localizationGO:00603411360.012
immune system processGO:00023763470.012
organic hydroxy compound metabolic processGO:1901615830.012
positive regulation of cell migrationGO:003033520.012
regulation of cell cycle processGO:00105641810.012
secretion by cellGO:00329401010.012
homeostatic processGO:00425921990.012
negative regulation of macromolecule biosynthetic processGO:00105582700.012
immune response regulating signaling pathwayGO:000276420.012
spindle organizationGO:00070512530.011
purine ribonucleoside metabolic processGO:00461281270.011
proteolysisGO:00065081920.011
carbohydrate derivative catabolic processGO:19011361180.011
regulation of epithelial cell proliferationGO:005067840.011
cell maturationGO:00484691440.011
embryonic development via the syncytial blastodermGO:00017001480.011
tissue morphogenesisGO:00487292970.011
nuclear divisionGO:00002803320.011
compound eye photoreceptor cell differentiationGO:00017511400.011
negative regulation of rna biosynthetic processGO:19026792400.011
nucleoside phosphate catabolic processGO:19012921100.011
developmental maturationGO:00217001720.011
cellular response to nitrogen compoundGO:1901699510.011
glycosyl compound catabolic processGO:19016581120.011
multicellular organismal agingGO:00102591400.011
nucleoside catabolic processGO:00091641120.011
tissue deathGO:00162711020.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
regulation of mitotic cell cycleGO:00073461900.011
biological adhesionGO:00226101380.011
ribonucleotide catabolic processGO:00092611090.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of hydrolase activityGO:0051336970.011
positive regulation of hydrolase activityGO:0051345780.011
establishment of protein localizationGO:00451841630.011
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.011
salivary gland histolysisGO:0035070880.011
regulation of protein localizationGO:0032880760.011
organelle fusionGO:0048284460.011
nephron developmentGO:007200630.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
nitrogen compound transportGO:0071705850.011
nucleobase containing compound catabolic processGO:00346551650.011
eye morphogenesisGO:00485922600.011
regulation of cell shapeGO:00083601130.011
cell adhesionGO:00071551360.011
intracellular transportGO:00469072280.011
cellular protein complex assemblyGO:0043623710.011
eye developmentGO:00016543230.011
negative regulation of cellular metabolic processGO:00313243820.011
nucleobase containing small molecule metabolic processGO:00550861740.010
purine ribonucleotide metabolic processGO:00091501450.010
guanosine containing compound metabolic processGO:1901068740.010
regulation of multicellular organismal developmentGO:20000264140.010
positive regulation of phosphate metabolic processGO:00459371390.010
response to organophosphorusGO:004668320.010
mitotic spindle organizationGO:00070522200.010
histolysisGO:00075591020.010
regulation of cell deathGO:00109411730.010
regulation of response to external stimulusGO:00321011150.010
negative regulation of nucleic acid templated transcriptionGO:19035072400.010
nucleoside metabolic processGO:00091161270.010
autophagyGO:00069141080.010
negative regulation of cellular biosynthetic processGO:00313272770.010
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
response to other organismGO:00517072930.010
positive regulation of catabolic processGO:00098961050.010
gtp metabolic processGO:0046039720.010

HPS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012
musculoskeletal system diseaseDOID:1700.011