IMP: Integrative Multi-species Prediction

Drosophila melanogaster

262 known processes

pros (Dmel_CG17228)

prospero

(Aliases: l(3)rL433,anon-WO0140519.15,0441/16,DMPROSPER,l(3)j6E2,pro,l(3)rH013,Pros,l(3)rJ806,0563/18,Voila,1135/09,0671/02,1135/07,l(3)10419,0664/07,0763/13,Dmel\CG17228,CG17228,l(3)rI160,0320/10,671/2,0244/09,1316/02,PROS-1,PROS-2,l(3)j12C8,0585/13,0989/01,l(3)rK204,l(3)rK137,DROPROSA,0451/09,1167/13,PROS,Prosp,l(3)rO534,BcDNA:HL08040)

FLYBASE: FBgn0004595
Entrez: 41363
UniProtKB: P29617

Process Predictions
Disease Predictions

pros biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon development	GO:0061564	297	1.000
axonogenesis	GO:0007409	290	0.998
dendrite morphogenesis	GO:0048813	199	0.995
axon guidance	GO:0007411	233	0.982
regulation of dendrite morphogenesis	GO:0048814	28	0.967
regulation of multicellular organismal development	GO:2000026	414	0.937
regulation of cell development	GO:0060284	215	0.926
dendrite guidance	GO:0070983	21	0.909
cell fate determination	GO:0001709	91	0.908	Mouse
regulation of cell differentiation	GO:0045595	302	0.902
neuroblast differentiation	GO:0014016	29	0.900
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.895
negative regulation of transcription dna templated	GO:0045892	237	0.892
dendrite development	GO:0016358	204	0.880
regulation of r7 cell differentiation	GO:0045676	15	0.869
r7 cell differentiation	GO:0045466	43	0.850
neuron projection guidance	GO:0097485	241	0.818
chemotaxis	GO:0006935	249	0.758
eye photoreceptor cell development	GO:0042462	81	0.742
multi organism reproductive behavior	GO:0044705	121	0.712
growth	GO:0040007	359	0.706	Mouse
motor neuron axon guidance	GO:0008045	58	0.701
cell proliferation	GO:0008283	299	0.682
positive regulation of developmental process	GO:0051094	143	0.656	Mouse
compound eye photoreceptor development	GO:0042051	78	0.650
negative regulation of gene expression	GO:0010629	387	0.645
regulation of neuron differentiation	GO:0045664	103	0.633
cell motility	GO:0048870	251	0.627	Zebrafish Mouse
regulation of epithelial cell proliferation	GO:0050678	4	0.610
positive regulation of macromolecule metabolic process	GO:0010604	405	0.587
mating	GO:0007618	120	0.585
regulation of protein metabolic process	GO:0051246	256	0.573
developmental growth	GO:0048589	280	0.565	Mouse
compound eye photoreceptor cell differentiation	GO:0001751	140	0.565
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.552	Mouse
regulation of photoreceptor cell differentiation	GO:0046532	34	0.539
negative regulation of biosynthetic process	GO:0009890	277	0.533
positive regulation of cellular component organization	GO:0051130	156	0.511	Mouse
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.504
regulation of localization	GO:0032879	275	0.496
transcription from rna polymerase ii promoter	GO:0006366	368	0.495
neuroblast development	GO:0014019	13	0.480
positive regulation of nervous system development	GO:0051962	69	0.477	Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.471	Mouse
developmental maturation	GO:0021700	172	0.463
forebrain development	GO:0030900	2	0.458	Zebrafish Mouse
cell maturation	GO:0048469	144	0.446
protein modification process	GO:0036211	438	0.440
immune system process	GO:0002376	347	0.440
larval behavior	GO:0030537	42	0.439
regulation of cellular component biogenesis	GO:0044087	201	0.415	Mouse
dorsal ventral axon guidance	GO:0033563	2	0.413
multi multicellular organism process	GO:0044706	123	0.413
regulation of nervous system development	GO:0051960	248	0.399
cell fate specification	GO:0001708	71	0.388
regulation of neurogenesis	GO:0050767	158	0.371
compound eye morphogenesis	GO:0001745	249	0.369
regulation of cellular protein metabolic process	GO:0032268	243	0.355
nephron tubule morphogenesis	GO:0072078	3	0.339
cell growth	GO:0016049	108	0.339
regulation of growth	GO:0040008	233	0.338	Mouse
response to alcohol	GO:0097305	95	0.330
organonitrogen compound metabolic process	GO:1901564	318	0.323
cellular macromolecule localization	GO:0070727	220	0.320
regulation of catalytic activity	GO:0050790	185	0.317
single organism behavior	GO:0044708	391	0.307
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.303
negative regulation of rna biosynthetic process	GO:1902679	240	0.300
positive regulation of catalytic activity	GO:0043085	118	0.298
neuron projection extension	GO:1990138	32	0.287
telencephalon development	GO:0021537	2	0.285	Mouse
regulation of peptidase activity	GO:0052547	39	0.278
segmentation	GO:0035282	207	0.267
negative regulation of cellular metabolic process	GO:0031324	382	0.267
regulation of cytoskeleton organization	GO:0051493	89	0.260	Mouse
regulation of proteolysis	GO:0030162	87	0.257
photoreceptor cell development	GO:0042461	96	0.249
mesoderm development	GO:0007498	78	0.246
photoreceptor cell differentiation	GO:0046530	170	0.244
response to wounding	GO:0009611	94	0.240
locomotory behavior	GO:0007626	176	0.240
protein transport	GO:0015031	155	0.237
programmed cell death	GO:0012501	257	0.236
regulation of dendrite development	GO:0050773	37	0.234
chromosome organization	GO:0051276	360	0.234
regionalization	GO:0003002	416	0.234
regulation of molecular function	GO:0065009	217	0.230	Zebrafish
positive regulation of biosynthetic process	GO:0009891	316	0.230	Mouse
positive regulation of molecular function	GO:0044093	136	0.222
establishment of ommatidial planar polarity	GO:0042067	49	0.216
regulation of organelle organization	GO:0033043	196	0.206	Mouse
brain development	GO:0007420	120	0.200
kidney development	GO:0001822	3	0.198
positive regulation of neuron differentiation	GO:0045666	26	0.195	Mouse
taxis	GO:0042330	304	0.193
positive regulation of cellular protein metabolic process	GO:0032270	118	0.192
regulation of anatomical structure morphogenesis	GO:0022603	242	0.190
body morphogenesis	GO:0010171	2	0.190
determination of adult lifespan	GO:0008340	137	0.183
ommatidial rotation	GO:0016318	20	0.183
positive regulation of neurogenesis	GO:0050769	41	0.182	Mouse
cellular protein modification process	GO:0006464	438	0.181
phosphorylation	GO:0016310	294	0.181
eye morphogenesis	GO:0048592	260	0.180
neuroblast division	GO:0055057	35	0.179
negative regulation of epithelial cell proliferation	GO:0050680	4	0.179
regulation of protein modification process	GO:0031399	112	0.177
phenol containing compound metabolic process	GO:0018958	57	0.176
negative regulation of cellular biosynthetic process	GO:0031327	277	0.172
sensory organ morphogenesis	GO:0090596	260	0.171
regulation of cell proliferation	GO:0042127	163	0.171
eye photoreceptor cell fate commitment	GO:0042706	37	0.170
axonal fasciculation	GO:0007413	12	0.168
synapse assembly	GO:0007416	143	0.164
regulation of synapse structure and activity	GO:0050803	128	0.163
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.162
positive regulation of programmed cell death	GO:0043068	62	0.161
stem cell development	GO:0048864	79	0.161	Mouse
renal tubule development	GO:0061326	64	0.158
tissue migration	GO:0090130	155	0.158
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.156	Mouse
proteolysis	GO:0006508	192	0.155
peripheral nervous system development	GO:0007422	52	0.155
head development	GO:0060322	135	0.152
negative regulation of cellular component organization	GO:0051129	108	0.150
olfactory learning	GO:0008355	56	0.149
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.148
glial cell development	GO:0021782	27	0.147
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.146
neuronal stem cell division	GO:0036445	35	0.146
stem cell differentiation	GO:0048863	117	0.145
cell division	GO:0051301	248	0.140
protein phosphorylation	GO:0006468	169	0.138
neuroblast fate commitment	GO:0014017	19	0.138
regulation of phosphorus metabolic process	GO:0051174	210	0.137
regulation of cellular component movement	GO:0051270	42	0.136	Zebrafish
negative regulation of growth	GO:0045926	84	0.136
ventral cord development	GO:0007419	16	0.135
blastoderm segmentation	GO:0007350	159	0.135
response to endogenous stimulus	GO:0009719	119	0.134
eye photoreceptor cell differentiation	GO:0001754	145	0.132
axon extension	GO:0048675	32	0.131
blood circulation	GO:0008015	26	0.130
cellular protein localization	GO:0034613	160	0.129
larval locomotory behavior	GO:0008345	27	0.128
gland development	GO:0048732	191	0.128	Mouse
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.126
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.125
response to nutrient levels	GO:0031667	114	0.122
establishment or maintenance of cell polarity	GO:0007163	167	0.117
synaptic transmission	GO:0007268	288	0.115
pole plasm oskar mrna localization	GO:0045451	46	0.114
regulation of membrane potential	GO:0042391	35	0.114
nephron tubule development	GO:0072080	3	0.114
neural precursor cell proliferation	GO:0061351	75	0.113
kidney epithelium development	GO:0072073	3	0.112
regulation of anatomical structure size	GO:0090066	163	0.111
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.111
muscle organ development	GO:0007517	127	0.110	Mouse
learning	GO:0007612	75	0.109
wound healing	GO:0042060	75	0.108
retinal ganglion cell axon guidance	GO:0031290	12	0.106
central nervous system development	GO:0007417	201	0.105
positive regulation of axonogenesis	GO:0050772	2	0.105
regulation of organ morphogenesis	GO:2000027	78	0.105
regulation of axon extension involved in axon guidance	GO:0048841	4	0.104
synapse organization	GO:0050808	196	0.102
cellular response to hormone stimulus	GO:0032870	44	0.097
positive regulation of multicellular organismal process	GO:0051240	143	0.096	Mouse
glial cell differentiation	GO:0010001	35	0.094
small molecule metabolic process	GO:0044281	305	0.094
branch fusion open tracheal system	GO:0035147	17	0.093
negative regulation of nervous system development	GO:0051961	92	0.093
embryonic pattern specification	GO:0009880	174	0.091
single organism cellular localization	GO:1902580	180	0.091
regulation of programmed cell death	GO:0043067	152	0.091
mating behavior sex discrimination	GO:0048047	7	0.091
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.091
positive regulation of cell development	GO:0010720	61	0.090	Mouse
regulation of cell morphogenesis	GO:0022604	163	0.089
death	GO:0016265	284	0.089
signal transduction by phosphorylation	GO:0023014	107	0.087
morphogenesis of a branching epithelium	GO:0061138	45	0.086	Mouse
cellular response to chemical stimulus	GO:0070887	199	0.085
cell adhesion	GO:0007155	136	0.084
protein maturation	GO:0051604	71	0.084
courtship behavior	GO:0007619	68	0.084
reproductive behavior	GO:0019098	122	0.083
neuron maturation	GO:0042551	31	0.082
hematopoietic or lymphoid organ development	GO:0048534	57	0.081
regulation of transport	GO:0051049	181	0.080
cellular response to organic substance	GO:0071310	132	0.080
stem cell fate commitment	GO:0048865	25	0.078
negative regulation of rna metabolic process	GO:0051253	251	0.078
negative regulation of response to stimulus	GO:0048585	258	0.077
catabolic process	GO:0009056	409	0.076
regulation of cell death	GO:0010941	173	0.076
regulation of protein kinase activity	GO:0045859	51	0.076
response to mechanical stimulus	GO:0009612	28	0.075
embryonic hemopoiesis	GO:0035162	26	0.075
axon extension involved in axon guidance	GO:0048846	10	0.075
positive regulation of axon extension	GO:0045773	2	0.074
establishment of localization in cell	GO:0051649	402	0.072
spinal cord development	GO:0021510	1	0.072
macromolecular complex assembly	GO:0065003	256	0.071
chemosensory behavior	GO:0007635	106	0.070
detection of stimulus	GO:0051606	156	0.069
multicellular organismal signaling	GO:0035637	12	0.068
axon ensheathment	GO:0008366	10	0.068
organic substance catabolic process	GO:1901575	308	0.068
tube development	GO:0035295	244	0.068
transmission of nerve impulse	GO:0019226	12	0.068
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.067	Mouse
hindbrain development	GO:0030902	2	0.067	Mouse
respiratory system development	GO:0060541	213	0.066
negative regulation of developmental process	GO:0051093	201	0.066
positive regulation of r7 cell differentiation	GO:0045678	7	0.065
positive regulation of phosphorus metabolic process	GO:0010562	139	0.065
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.065
regulation of cell projection organization	GO:0031344	92	0.065
negative regulation of cell communication	GO:0010648	223	0.064
histone modification	GO:0016570	106	0.064
anterior posterior axis specification embryo	GO:0008595	103	0.064
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.063
regulation of phosphorylation	GO:0042325	147	0.063
protein localization	GO:0008104	284	0.062
regulation of apoptotic process	GO:0042981	130	0.061
cellular response to oxygen containing compound	GO:1901701	79	0.061
peripheral nervous system neuron differentiation	GO:0048934	8	0.061	Zebrafish
negative regulation of developmental growth	GO:0048640	64	0.060
positive regulation of phosphate metabolic process	GO:0045937	139	0.060
positive regulation of cell death	GO:0010942	69	0.060
regulation of neuroblast proliferation	GO:1902692	34	0.059
neuronal action potential	GO:0019228	10	0.058
oocyte construction	GO:0007308	112	0.058
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.057
divalent inorganic cation transport	GO:0072511	30	0.057
response to extracellular stimulus	GO:0009991	116	0.057
photoreceptor cell fate commitment	GO:0046552	41	0.056
cell projection assembly	GO:0030031	94	0.056
neuronal stem cell maintenance	GO:0097150	4	0.056	Mouse
neuron remodeling	GO:0016322	29	0.055
nephron epithelium development	GO:0072009	3	0.054
epithelial cell migration	GO:0010631	148	0.054
neuroblast fate determination	GO:0007400	12	0.054
protein complex assembly	GO:0006461	200	0.054
mapk cascade	GO:0000165	107	0.053
embryo development ending in birth or egg hatching	GO:0009792	152	0.053
chromatin modification	GO:0016568	147	0.053
embryonic morphogenesis	GO:0048598	206	0.053	Mouse
oocyte differentiation	GO:0009994	145	0.052
positive regulation of intracellular signal transduction	GO:1902533	116	0.052
action potential	GO:0001508	13	0.052
response to organic substance	GO:0010033	284	0.052
establishment of planar polarity	GO:0001736	87	0.051
gastrulation	GO:0007369	70	0.051
muscle cell differentiation	GO:0042692	103	0.051	Zebrafish Mouse
asymmetric cell division	GO:0008356	37	0.050
larval development	GO:0002164	104	0.050	Worm
cell type specific apoptotic process	GO:0097285	38	0.050
reproductive structure development	GO:0048608	74	0.050
adherens junction organization	GO:0034332	27	0.049
asymmetric stem cell division	GO:0098722	49	0.049
cellular component disassembly	GO:0022411	46	0.047
positive regulation of protein modification process	GO:0031401	58	0.047
endocytosis	GO:0006897	310	0.047
asymmetric protein localization	GO:0008105	33	0.047
tripartite regional subdivision	GO:0007351	103	0.047
ensheathment of neurons	GO:0007272	10	0.046
establishment of spindle localization	GO:0051293	22	0.045
epithelium migration	GO:0090132	148	0.045
stem cell division	GO:0017145	69	0.045
axis specification	GO:0009798	167	0.045
morphogenesis of embryonic epithelium	GO:0016331	94	0.045
neuron fate commitment	GO:0048663	50	0.045
positive regulation of gene expression	GO:0010628	290	0.044
epithelial tube morphogenesis	GO:0060562	88	0.044
positive regulation of endopeptidase activity	GO:0010950	26	0.043
male mating behavior	GO:0060179	70	0.043
regulation of kinase activity	GO:0043549	53	0.043
connective tissue development	GO:0061448	3	0.043
negative regulation of catalytic activity	GO:0043086	42	0.043
embryonic development via the syncytial blastoderm	GO:0001700	148	0.042
circadian rhythm	GO:0007623	105	0.041	Mouse
negative regulation of protein metabolic process	GO:0051248	85	0.041
reproductive system development	GO:0061458	74	0.041
branching morphogenesis of an epithelial tube	GO:0048754	45	0.040
gliogenesis	GO:0042063	80	0.040
positive regulation of cell proliferation	GO:0008284	47	0.040	Mouse
epithelial cell proliferation	GO:0050673	15	0.040	Mouse
regulation of actin cytoskeleton organization	GO:0032956	42	0.040	Mouse
regulation of cellular amine metabolic process	GO:0033238	3	0.040
single organism catabolic process	GO:0044712	228	0.040
hemocyte differentiation	GO:0042386	38	0.040
aging	GO:0007568	143	0.039
homophilic cell adhesion via plasma membrane adhesion molecules	GO:0007156	18	0.039
lateral inhibition	GO:0046331	206	0.039
embryonic axis specification	GO:0000578	107	0.039
central nervous system neuron differentiation	GO:0021953	8	0.039	Zebrafish Mouse
organelle fission	GO:0048285	340	0.038
associative learning	GO:0008306	65	0.038
regulation of immune response	GO:0050776	118	0.038
positive regulation of protein metabolic process	GO:0051247	128	0.037
neuron recognition	GO:0008038	101	0.037
regulation of cell cell adhesion	GO:0022407	21	0.037
cellular ketone metabolic process	GO:0042180	24	0.036
central nervous system segmentation	GO:0035283	5	0.036
positive regulation of rna biosynthetic process	GO:1902680	266	0.036	Mouse
regulation of phosphate metabolic process	GO:0019220	210	0.036
regulation of cell growth	GO:0001558	43	0.036
endomembrane system organization	GO:0010256	119	0.036
cell junction organization	GO:0034330	57	0.036
positive regulation of signaling	GO:0023056	243	0.035
morphogenesis of an epithelium	GO:0002009	276	0.035	Mouse
establishment of protein localization	GO:0045184	163	0.035
regulation of vesicle mediated transport	GO:0060627	59	0.034
regulation of actin filament based process	GO:0032970	42	0.034	Mouse
negative regulation of signal transduction	GO:0009968	206	0.034
negative regulation of protein depolymerization	GO:1901880	23	0.033
response to oxygen levels	GO:0070482	59	0.033
axon midline choice point recognition	GO:0016199	26	0.033
regulation of synapse assembly	GO:0051963	94	0.033
epithelial cell migration open tracheal system	GO:0007427	32	0.033
positive regulation of photoreceptor cell differentiation	GO:0046534	12	0.033
feeding behavior	GO:0007631	50	0.033
olfactory behavior	GO:0042048	97	0.033
response to glucose	GO:0009749	2	0.032
asymmetric neuroblast division	GO:0055059	33	0.032
biological adhesion	GO:0022610	138	0.032
multicellular organismal reproductive behavior	GO:0033057	110	0.032
secretion	GO:0046903	109	0.032
cellular amine metabolic process	GO:0044106	12	0.032
multicellular organismal aging	GO:0010259	140	0.032
response to monosaccharide	GO:0034284	4	0.031
positive regulation of apoptotic process	GO:0043065	47	0.031
cell migration	GO:0016477	238	0.031	Zebrafish Mouse
regulation of embryonic pattern specification	GO:1902875	27	0.031
regulation of transferase activity	GO:0051338	58	0.031
retina development in camera type eye	GO:0060041	4	0.031
regulation of hydrolase activity	GO:0051336	97	0.031
anterior posterior axis specification	GO:0009948	109	0.031
central complex development	GO:0048036	9	0.031
spermatogenesis	GO:0007283	200	0.031
glial cell migration	GO:0008347	31	0.031
meiotic nuclear division	GO:0007126	151	0.031
intracellular transport	GO:0046907	228	0.031
protein processing	GO:0016485	68	0.031
regulation of endopeptidase activity	GO:0052548	36	0.030
determination of dorsal ventral asymmetry	GO:0048262	3	0.030
regulation of behavior	GO:0050795	75	0.030
positive regulation of cellular biosynthetic process	GO:0031328	316	0.030	Mouse
regulation of cell migration	GO:0030334	22	0.030	Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.030
response to organic cyclic compound	GO:0014070	89	0.030
positive regulation of cell communication	GO:0010647	250	0.030
dorsal ventral pattern formation	GO:0009953	133	0.030
regulation of protein phosphorylation	GO:0001932	64	0.029
brain morphogenesis	GO:0048854	16	0.029
cellular response to endogenous stimulus	GO:0071495	80	0.029
response to insulin	GO:0032868	29	0.029
nephron epithelium morphogenesis	GO:0072088	3	0.028
response to hormone	GO:0009725	45	0.028
regulation of oocyte development	GO:0060281	27	0.028
epidermal cell differentiation	GO:0009913	51	0.028	Zebrafish
oocyte axis specification	GO:0007309	108	0.028
regulation of cellular localization	GO:0060341	136	0.028
negative regulation of phosphorylation	GO:0042326	35	0.027
cellular response to organonitrogen compound	GO:0071417	36	0.027
regulation of hemocyte differentiation	GO:0045610	22	0.027
vesicle mediated transport	GO:0016192	381	0.027
chaeta development	GO:0022416	97	0.027
nephron morphogenesis	GO:0072028	3	0.027
chromatin organization	GO:0006325	207	0.027
actin filament based process	GO:0030029	220	0.026	Zebrafish Mouse
positive regulation of response to stimulus	GO:0048584	323	0.026
negative regulation of synapse assembly	GO:0051964	39	0.026
positive regulation of proteolysis	GO:0045862	52	0.026
cell death	GO:0008219	279	0.026
establishment of tissue polarity	GO:0007164	87	0.026
epithelial cell development	GO:0002064	274	0.026	Mouse
positive regulation of peptidase activity	GO:0010952	29	0.026
phagocytosis	GO:0006909	215	0.025
sensory perception	GO:0007600	196	0.025
peptidyl amino acid modification	GO:0018193	105	0.025
anatomical structure homeostasis	GO:0060249	97	0.025
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.025	Mouse
ameboidal type cell migration	GO:0001667	151	0.025
negative regulation of molecular function	GO:0044092	51	0.024	Zebrafish
negative regulation of dendrite morphogenesis	GO:0050774	2	0.024
negative regulation of cellular protein metabolic process	GO:0032269	85	0.024
adult behavior	GO:0030534	137	0.024
mating behavior	GO:0007617	106	0.024
digestive system development	GO:0055123	149	0.024
regulation of chromosome organization	GO:0033044	64	0.024
metal ion transport	GO:0030001	74	0.024
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.024
cellular response to nitrogen compound	GO:1901699	51	0.024
response to ethanol	GO:0045471	59	0.024
digestive tract morphogenesis	GO:0048546	127	0.024
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.024
r7 cell development	GO:0045467	14	0.023
compound eye development	GO:0048749	307	0.023
regulation of eye photoreceptor cell development	GO:0042478	13	0.023
tissue morphogenesis	GO:0048729	297	0.023
positive regulation of axon guidance	GO:1902669	1	0.023
response to oxygen containing compound	GO:1901700	200	0.023
regulation of glial cell differentiation	GO:0045685	1	0.023
cranial nerve development	GO:0021545	1	0.023
negative regulation of epithelial cell migration	GO:0010633	1	0.023
pigment metabolic process	GO:0042440	84	0.022
rna localization	GO:0006403	115	0.022
regulation of notch signaling pathway	GO:0008593	100	0.022
carbohydrate homeostasis	GO:0033500	12	0.022
positive regulation of cell differentiation	GO:0045597	64	0.022	Mouse
open tracheal system development	GO:0007424	204	0.022
morphogenesis of a branching structure	GO:0001763	45	0.022	Mouse
intracellular mrna localization	GO:0008298	66	0.022
regulation of cell adhesion	GO:0030155	27	0.022
eye development	GO:0001654	323	0.022
cardiocyte differentiation	GO:0035051	29	0.021	Mouse
cell cycle arrest	GO:0007050	4	0.021
regulation of axonogenesis	GO:0050770	32	0.021
stem cell fate determination	GO:0048867	15	0.021
mesoderm morphogenesis	GO:0048332	22	0.021
photoreceptor cell axon guidance	GO:0072499	23	0.021
regulation of developmental growth	GO:0048638	174	0.021	Mouse
renal system development	GO:0072001	72	0.021
negative regulation of phosphate metabolic process	GO:0045936	45	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
cell cell junction organization	GO:0045216	55	0.021
mushroom body development	GO:0016319	70	0.021
carbohydrate derivative metabolic process	GO:1901135	217	0.020
cell fate commitment involved in pattern specification	GO:0060581	31	0.020
nucleoside metabolic process	GO:0009116	127	0.020
male courtship behavior veined wing extension	GO:0048065	22	0.020
purine containing compound metabolic process	GO:0072521	155	0.020
detection of stimulus involved in sensory perception	GO:0050906	92	0.020
response to inorganic substance	GO:0010035	44	0.020
regulation of axon guidance	GO:1902667	10	0.020
developmental cell growth	GO:0048588	52	0.020
cell recognition	GO:0008037	102	0.019
response to radiation	GO:0009314	155	0.019
imaginal disc growth	GO:0007446	37	0.019
organic hydroxy compound metabolic process	GO:1901615	83	0.019
stem cell proliferation	GO:0072089	88	0.019
regulation of pole plasm oskar mrna localization	GO:0007317	27	0.019
cell cell adhesion mediated by cadherin	GO:0044331	6	0.019
epithelial cell proliferation involved in renal tubule morphogenesis	GO:2001013	11	0.019
neuromuscular process	GO:0050905	21	0.019
muscle structure development	GO:0061061	224	0.019	Zebrafish Mouse
convergent extension	GO:0060026	2	0.018
positive regulation of growth	GO:0045927	75	0.018	Mouse
chromosome segregation	GO:0007059	157	0.018
regulation of system process	GO:0044057	36	0.018
retinal cell programmed cell death	GO:0046666	25	0.018
imaginal disc pattern formation	GO:0007447	91	0.018
positive regulation of cell projection organization	GO:0031346	29	0.018
regulation of cellular amino acid metabolic process	GO:0006521	0	0.018
regulation of multi organism process	GO:0043900	131	0.018
single organism biosynthetic process	GO:0044711	206	0.018
pigmentation	GO:0043473	75	0.018
ribonucleotide metabolic process	GO:0009259	145	0.018
regulation of nuclear division	GO:0051783	58	0.018
regulation of cell cycle process	GO:0010564	181	0.017	Mouse
protein complex biogenesis	GO:0070271	201	0.017
axon choice point recognition	GO:0016198	26	0.017
rna processing	GO:0006396	147	0.017
cellular catabolic process	GO:0044248	372	0.017
positive regulation of cellular amine metabolic process	GO:0033240	0	0.017
regeneration	GO:0031099	16	0.017
synaptic growth at neuromuscular junction	GO:0051124	119	0.017
vesicle localization	GO:0051648	55	0.017
organonitrogen compound biosynthetic process	GO:1901566	117	0.017
cellular response to hexose stimulus	GO:0071331	1	0.017
oocyte development	GO:0048599	124	0.017
multi organism behavior	GO:0051705	175	0.017
homeostatic process	GO:0042592	199	0.017
single organism intracellular transport	GO:1902582	207	0.017
regulation of endocytosis	GO:0030100	37	0.017
regulation of compound eye photoreceptor development	GO:0045314	12	0.017
r8 cell differentiation	GO:0045465	13	0.017
positive regulation of transcription dna templated	GO:0045893	266	0.017	Mouse
regulation of catabolic process	GO:0009894	170	0.017
negative regulation of neurogenesis	GO:0050768	53	0.017
protein localization to organelle	GO:0033365	82	0.017
neuroblast proliferation	GO:0007405	74	0.016
regulation of embryonic development	GO:0045995	68	0.016
response to hypoxia	GO:0001666	53	0.016
regulation of epithelial cell migration	GO:0010632	12	0.016
digestive tract development	GO:0048565	149	0.016
male courtship behavior veined wing generated song production	GO:0045433	20	0.016
outflow tract morphogenesis	GO:0003151	4	0.016
organic substance transport	GO:0071702	257	0.016

pros disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.109
musculoskeletal system disease	DOID:17	0.050
nervous system disease	DOID:863	0.043
cardiovascular system disease	DOID:1287	0.034
disease of cellular proliferation	DOID:14566	0.018
disease of metabolism	DOID:0014667	0.016

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