Drosophila melanogaster

19 known processes

rtGEF (Dmel_CG10043)

rho-type guanine exchange factor

(Aliases: rhoGEF,DrhoGEF,dpix,DrtGEF,RhoGEF,ARHGEF7,beta-PIX,dPix,38C.40,Rho/RacGEF,CG10043,Dmel\CG10043)

rtGEF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
synaptic transmissionGO:00072682880.837
establishment of vesicle localizationGO:0051650510.768
synaptic vesicle recyclingGO:0036465280.705
synaptic vesicle transportGO:0048489500.696
synapse organizationGO:00508081960.667
regulation of multicellular organismal developmentGO:20000264140.655
signal releaseGO:0023061490.587
establishment of localization in cellGO:00516494020.551
synaptic vesicle endocytosisGO:0048488280.543
regulation of cell developmentGO:00602842150.525
Human
neuromuscular junction developmentGO:00075281490.500
establishment of organelle localizationGO:00516561220.462
regulation of neurogenesisGO:00507671580.451
regulation of neuron projection developmentGO:0010975690.444
regulation of nervous system developmentGO:00519602480.436
regulation of synaptic growth at neuromuscular junctionGO:0008582890.428
protein modification processGO:00362114380.421
organelle localizationGO:00516401480.385
regulation of neuron differentiationGO:00456641030.384
regulation of cellular component biogenesisGO:00440872010.372
regulation of cell differentiationGO:00455953020.364
Human
synapse assemblyGO:00074161430.361
regulation of synapse organizationGO:00508071100.348
synaptic growth at neuromuscular junctionGO:00511241190.345
vesicle localizationGO:0051648550.341
organonitrogen compound metabolic processGO:19015643180.332
Human Mouse
positive regulation of secretionGO:0051047220.331
establishment of synaptic vesicle localizationGO:0097480500.330
positive regulation of nitrogen compound metabolic processGO:00511733540.320
Human Mouse
neurotransmitter transportGO:0006836370.315
tube developmentGO:00352952440.310
synaptic vesicle exocytosisGO:0016079160.299
axon developmentGO:00615642970.288
cognitionGO:00508901410.278
regulation of cytoskeleton organizationGO:0051493890.249
neurotransmitter secretionGO:0007269350.248
epithelial cell migrationGO:00106311480.246
learning or memoryGO:00076111410.242
tissue migrationGO:00901301550.232
negative regulation of cellular component organizationGO:00511291080.229
positive regulation of synapse assemblyGO:0051965290.228
cellular protein modification processGO:00064644380.220
peptidyl amino acid modificationGO:00181931050.218
locomotory behaviorGO:00076261760.209
tube morphogenesisGO:00352391910.208
neurological system processGO:00508773580.198
cell motilityGO:00488702510.187
Human Rat
positive regulation of cell migrationGO:003033520.179
Human
regulation of synapse assemblyGO:0051963940.178
axonogenesisGO:00074092900.173
regulation of anatomical structure morphogenesisGO:00226032420.172
Human
developmental growthGO:00485892800.170
positive regulation of biosynthetic processGO:00098913160.168
g protein coupled receptor signaling pathwayGO:00071861360.164
secretionGO:00469031090.163
tissue morphogenesisGO:00487292970.161
ribonucleotide metabolic processGO:00092591450.159
Human Mouse
single organism behaviorGO:00447083910.155
axon extensionGO:0048675320.153
single organism membrane organizationGO:0044802930.153
single organism membrane fusionGO:0044801420.151
positive regulation of exocytosisGO:004592140.146
positive regulation of transcription dna templatedGO:00458932660.139
organophosphate metabolic processGO:00196371950.138
Human Mouse
positive regulation of macromolecule metabolic processGO:00106044050.138
regulation of cell cycleGO:00517262910.137
positive regulation of secretion by cellGO:1903532200.136
intracellular signal transductionGO:00355563000.134
Rat
neuron projection extensionGO:1990138320.132
regulation of transportGO:00510491810.132
ameboidal type cell migrationGO:00016671510.130
Human
sensory perceptionGO:00076001960.127
regulation of cell morphogenesisGO:00226041630.126
Human
carbohydrate derivative metabolic processGO:19011352170.125
Human Mouse
synaptic vesicle localizationGO:0097479530.125
regulation of cellular localizationGO:00603411360.124
regulation of organelle organizationGO:00330431960.118
positive regulation of signalingGO:00230562430.118
localization of cellGO:00516742570.118
Human Rat
memoryGO:0007613940.114
positive regulation of rna biosynthetic processGO:19026802660.113
rhythmic excitationGO:004317910.113
regulation of transcription from rna polymerase ii promoterGO:00063573780.113
small molecule metabolic processGO:00442813050.112
Human Mouse
regulation of neurotransmitter levelsGO:0001505380.111
protein complex biogenesisGO:00702712010.110
nucleobase containing small molecule metabolic processGO:00550861740.110
Human Mouse
epithelium migrationGO:00901321480.109
positive regulation of nucleobase containing compound metabolic processGO:00459353320.109
Human Mouse
positive regulation of rna metabolic processGO:00512542710.108
phosphorylationGO:00163102940.107
vesicle organizationGO:0016050440.107
neuron neuron synaptic transmissionGO:0007270140.105
regulation of growthGO:00400082330.101
ion transportGO:00068111450.101
detection of stimulusGO:00516061560.101
positive regulation of nucleic acid templated transcriptionGO:19035082660.100
chromosome organizationGO:00512763600.099
protein phosphorylationGO:00064681690.098
regulation of dendrite morphogenesisGO:0048814280.098
regulation of behaviorGO:0050795750.098
maintenance of presynaptic active zone structureGO:004879080.096
regulation of anatomical structure sizeGO:00900661630.095
single organism intracellular transportGO:19025822070.095
membrane organizationGO:00610241120.094
regulation of excitatory postsynaptic membrane potentialGO:006007930.092
positive regulation of cell communicationGO:00106472500.092
regulation of secretion by cellGO:1903530390.090
secretion by cellGO:00329401010.089
purine nucleotide metabolic processGO:00061631460.088
Human Mouse
regulation of organ morphogenesisGO:2000027780.088
positive regulation of gene expressionGO:00106282900.087
positive regulation of neuromuscular synaptic transmissionGO:190007540.086
regulation of protein metabolic processGO:00512462560.086
embryonic morphogenesisGO:00485982060.086
regulation of neurotransmitter secretionGO:0046928140.085
regulation of catabolic processGO:00098941700.085
Human Mouse
sensory perception of smellGO:0007608800.085
single organism biosynthetic processGO:00447112060.084
taxisGO:00423303040.083
regulation of cell morphogenesis involved in differentiationGO:0010769610.083
Human
nuclear divisionGO:00002803320.083
organelle fusionGO:0048284460.082
regulation of developmental growthGO:00486381740.082
positive regulation of synaptic transmissionGO:0050806150.081
single organism catabolic processGO:00447122280.081
Human Mouse
multi organism reproductive behaviorGO:00447051210.081
glycosyl compound catabolic processGO:19016581120.081
Human Mouse
detection of stimulus involved in sensory perceptionGO:0050906920.080
developmental cell growthGO:0048588520.080
long term memoryGO:0007616620.079
neuromuscular synaptic transmissionGO:0007274670.079
respiratory system developmentGO:00605412130.079
mitotic nuclear divisionGO:00070672130.078
cellular catabolic processGO:00442483720.077
Human Mouse
actin filament based processGO:00300292200.077
chemotaxisGO:00069352490.076
regulation of cell projection organizationGO:0031344920.075
Human
digestive tract morphogenesisGO:00485461270.075
mesoderm morphogenesisGO:0048332220.075
cell migrationGO:00164772380.074
Human Rat
forebrain developmentGO:003090020.074
catabolic processGO:00090564090.073
Human Mouse
vesicle mediated transportGO:00161923810.071
growthGO:00400073590.071
cellular ion homeostasisGO:0006873390.070
response to organic substanceGO:00100332840.070
organonitrogen compound catabolic processGO:19015651280.069
Human Mouse
regulation of synapse structure and activityGO:00508031280.067
positive regulation of cellular component biogenesisGO:0044089800.067
cyclic purine nucleotide metabolic processGO:0052652250.066
negative regulation of synapse assemblyGO:0051964390.066
organelle fissionGO:00482853400.066
membrane fusionGO:0061025420.066
cellular chemical homeostasisGO:0055082400.066
positive regulation of cellular biosynthetic processGO:00313283160.065
cation homeostasisGO:0055080510.065
positive regulation of cell motilityGO:200014730.065
Human
mitotic sister chromatid segregationGO:0000070870.065
response to abiotic stimulusGO:00096283410.065
morphogenesis of an epitheliumGO:00020092760.064
cellular amine metabolic processGO:0044106120.064
positive regulation of transportGO:0051050920.063
regulation of synaptic transmissionGO:0050804690.063
nucleoside phosphate metabolic processGO:00067531620.062
Human Mouse
organonitrogen compound biosynthetic processGO:19015661170.062
imaginal disc derived appendage developmentGO:00487373990.060
open tracheal system developmentGO:00074242040.059
negative regulation of developmental growthGO:0048640640.059
sensory organ morphogenesisGO:00905962600.059
carboxylic acid metabolic processGO:0019752920.059
organic substance transportGO:00717022570.059
response to mechanical stimulusGO:0009612280.058
purine containing compound metabolic processGO:00725211550.058
Human Mouse
establishment of spindle orientationGO:0051294180.058
negative regulation of microtubule depolymerizationGO:0007026210.058
negative regulation of biosynthetic processGO:00098902770.057
pigment metabolic processGO:0042440840.057
single organism cellular localizationGO:19025801800.057
biological adhesionGO:00226101380.057
Human
regulation of phosphorylationGO:00423251470.057
cellular cation homeostasisGO:0030003380.056
axon guidanceGO:00074112330.055
ribose phosphate metabolic processGO:00196931450.055
Human Mouse
regulation of protein complex disassemblyGO:0043244290.055
negative regulation of response to stimulusGO:00485852580.055
receptor clusteringGO:004311330.054
regulation of neuromuscular synaptic transmissionGO:1900073150.054
regulation of cellular amine metabolic processGO:003323830.053
exocytosisGO:0006887280.053
cellular modified amino acid metabolic processGO:0006575450.052
endocytosisGO:00068973100.052
columnar cuboidal epithelial cell differentiationGO:00020652560.052
embryonic pattern specificationGO:00098801740.052
regulation of secretionGO:0051046440.051
endomembrane system organizationGO:00102561190.051
sister chromatid segregationGO:0000819920.051
regulation of cell migrationGO:0030334220.051
Human
chromosome segregationGO:00070591570.051
organic acid metabolic processGO:00060821030.051
negative regulation of multicellular organismal processGO:00512411420.051
detection of chemical stimulusGO:0009593930.050
regulation of localizationGO:00328792750.050
Human
spindle organizationGO:00070512530.050
ovarian follicle cell developmentGO:00307072480.050
larval behaviorGO:0030537420.049
positive regulation of phosphate metabolic processGO:00459371390.049
Human Mouse
detection of external stimulusGO:0009581660.049
cellular protein localizationGO:00346131600.049
organic substance catabolic processGO:19015753080.049
Human Mouse
synaptic transmission glutamatergicGO:003524970.048
matingGO:00076181200.048
regulation of dendrite developmentGO:0050773370.047
nucleoside metabolic processGO:00091161270.047
Human Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459342610.047
ribonucleoside triphosphate metabolic processGO:00091991190.047
Human Mouse
neuron projection guidanceGO:00974852410.047
mapk cascadeGO:00001651070.046
negative regulation of nervous system developmentGO:0051961920.046
nucleoside triphosphate metabolic processGO:00091411200.046
Human Mouse
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.045
cellular homeostasisGO:0019725800.045
meiotic nuclear divisionGO:00071261510.045
regulation of membrane potentialGO:0042391350.045
regulation of mapk cascadeGO:0043408920.045
adult locomotory behaviorGO:0008344760.044
regulation of catalytic activityGO:00507901850.044
Human Mouse
retina development in camera type eyeGO:006004140.044
negative regulation of cellular metabolic processGO:00313243820.044
regulation of intracellular signal transductionGO:19025312360.044
Human Mouse
urogenital system developmentGO:0001655720.044
detection of chemical stimulus involved in sensory perceptionGO:0050907750.043
anterior posterior pattern specificationGO:00099521360.043
negative regulation of rna biosynthetic processGO:19026792400.043
negative regulation of growthGO:0045926840.042
homeostatic processGO:00425921990.042
post embryonic appendage morphogenesisGO:00351203850.042
negative regulation of nitrogen compound metabolic processGO:00511722650.041
regulation of cellular component movementGO:0051270420.041
Human
cellular macromolecule localizationGO:00707272200.041
regulation of synaptic vesicle exocytosisGO:200030030.041
positive regulation of response to stimulusGO:00485843230.041
microtubule based transportGO:0010970420.041
regulation of cell divisionGO:0051302720.040
hindgut morphogenesisGO:0007442580.040
regulation of mitotic cell cycleGO:00073461900.040
carbohydrate derivative catabolic processGO:19011361180.040
Human Mouse
purine ribonucleoside triphosphate metabolic processGO:00092051190.040
Human Mouse
intracellular protein transportGO:00068861040.039
positive regulation of synaptic transmission glutamatergicGO:005196830.039
purine ribonucleoside metabolic processGO:00461281270.039
Human Mouse
positive regulation of cellular component organizationGO:00511301560.038
Human
regulation of actin filament based processGO:0032970420.038
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.038
transmembrane transportGO:00550851390.037
epithelial cell developmentGO:00020642740.037
cytokinesisGO:0000910900.037
heart processGO:0003015370.036
epithelial tube morphogenesisGO:0060562880.036
positive regulation of signal transductionGO:00099672230.036
purine nucleoside triphosphate metabolic processGO:00091441190.036
Human Mouse
establishment of protein localizationGO:00451841630.036
regulation of vesicle mediated transportGO:0060627590.036
filopodium assemblyGO:0046847330.036
ribonucleotide catabolic processGO:00092611090.036
Human Mouse
negative regulation of developmental processGO:00510932010.036
response to heatGO:0009408630.035
eye developmentGO:00016543230.035
purine ribonucleotide metabolic processGO:00091501450.035
Human Mouse
digestive tract developmentGO:00485651490.035
mesoderm formationGO:0001707210.035
associative learningGO:0008306650.035
gtp catabolic processGO:0006184720.035
Human Mouse
regulation of receptor activityGO:0010469100.034
muscle system processGO:0003012210.034
positive regulation of multicellular organismal processGO:00512401430.034
gliogenesisGO:0042063800.034
Rat
guanosine containing compound metabolic processGO:1901068740.034
Human Mouse
cellular divalent inorganic cation homeostasisGO:0072503230.034
intracellular transportGO:00469072280.034
regionalizationGO:00030024160.033
ion transmembrane transportGO:00342201220.033
glial cell differentiationGO:0010001350.033
salivary gland developmentGO:00074311620.033
protein transportGO:00150311550.033
cell proliferationGO:00082832990.033
regulation of cellular response to stressGO:0080135890.033
regulation of epithelial cell migrationGO:0010632120.032
positive regulation of macromolecule biosynthetic processGO:00105572830.032
negative regulation of transcription dna templatedGO:00458922370.032
macromolecule catabolic processGO:00090571610.032
regulation of cell cycle processGO:00105641810.032
regulation of locomotionGO:0040012420.032
Human
adult behaviorGO:00305341370.032
cell divisionGO:00513012480.032
sensory perception of chemical stimulusGO:00076061160.032
cell deathGO:00082192790.032
Human
protein complex assemblyGO:00064612000.032
cellular amino acid metabolic processGO:0006520610.032
nucleotide metabolic processGO:00091171610.032
Human Mouse
kidney developmentGO:000182230.031
purine ribonucleoside catabolic processGO:00461301120.031
Human Mouse
behavioral response to painGO:004826630.031
purine nucleotide catabolic processGO:00061951090.031
Human Mouse
deathGO:00162652840.031
Human
nitrogen compound transportGO:0071705850.031
amine metabolic processGO:0009308120.031
detection of visible lightGO:0009584380.031
morphogenesis of embryonic epitheliumGO:0016331940.031
positive regulation of intracellular signal transductionGO:19025331160.030
regulation of proteolysisGO:0030162870.030
oxoacid metabolic processGO:00434361030.030
microtubule based movementGO:0007018510.030
regulation of molecular functionGO:00650092170.030
Human Mouse
response to endogenous stimulusGO:00097191190.030
developmental maturationGO:00217001720.030
axon cargo transportGO:0008088290.030
microtubule depolymerizationGO:0007019250.030
mesoderm developmentGO:0007498780.029
muscle organ developmentGO:00075171270.029
aromatic compound catabolic processGO:00194391660.029
Human Mouse
cell adhesionGO:00071551360.029
Human
peptide metabolic processGO:0006518800.029
negative regulation of macromolecule biosynthetic processGO:00105582700.029
negative regulation of cell communicationGO:00106482230.029
regulation of cell deathGO:00109411730.028
Human
columnar cuboidal epithelial cell developmentGO:00020662490.028
larval locomotory behaviorGO:0008345270.028
plasma membrane organizationGO:0007009260.028
dendrite developmentGO:00163582040.028
small gtpase mediated signal transductionGO:0007264880.028
Rat
meiotic cell cycleGO:00513211710.028
regulation of nuclear divisionGO:0051783580.028
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.028
positive regulation of phosphorus metabolic processGO:00105621390.028
Human Mouse
macromolecular complex assemblyGO:00650032560.028
developmental programmed cell deathGO:00106231380.027
actin filament organizationGO:00070151260.027
regulation of phosphorus metabolic processGO:00511742100.027
Human Mouse
developmental growth involved in morphogenesisGO:0060560650.027
cellular metal ion homeostasisGO:0006875310.027
regulation of programmed cell deathGO:00430671520.027
Human
compound eye developmentGO:00487493070.027
segmentationGO:00352822070.027
purine containing compound biosynthetic processGO:0072522300.026
camera type eye developmentGO:004301040.026
response to oxygen containing compoundGO:19017002000.026
divalent inorganic cation transportGO:0072511300.026
metal ion transportGO:0030001740.026
regulation of g protein coupled receptor protein signaling pathwayGO:0008277230.026
autophagyGO:00069141080.026
muscle contractionGO:0006936130.026
eye morphogenesisGO:00485922600.026
actin cytoskeleton organizationGO:00300362060.025
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
positive regulation of catabolic processGO:00098961050.025
Human Mouse
positive regulation of synaptic vesicle recyclingGO:190342340.025
positive regulation of purine nucleotide metabolic processGO:1900544550.025
Human Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072400.025
transcription from rna polymerase ii promoterGO:00063663680.025
mitotic cytokinesisGO:0000281500.025
l amino acid importGO:004309220.025
purine nucleoside triphosphate catabolic processGO:00091461080.025
Human Mouse
protein alkylationGO:0008213430.024
cellular ketone metabolic processGO:0042180240.024
cytosolic calcium ion homeostasisGO:0051480110.024
agingGO:00075681430.024
regulation of purine nucleotide metabolic processGO:1900542620.024
Human Mouse
programmed cell deathGO:00125012570.024
Human
brain developmentGO:00074201200.024
gastrulationGO:0007369700.024
cellular amide metabolic processGO:0043603800.024
purine nucleoside catabolic processGO:00061521120.024
Human Mouse
ribonucleoside catabolic processGO:00424541120.024
Human Mouse
dendrite morphogenesisGO:00488131990.024
ribonucleoside triphosphate catabolic processGO:00092031080.024
Human Mouse
inorganic ion transmembrane transportGO:0098660730.024
regulation of tube sizeGO:0035150460.024
cellular component disassemblyGO:0022411460.024
regulation of hormone levelsGO:0010817400.024
response to radiationGO:00093141550.023
microtubule polymerization or depolymerizationGO:0031109390.023
appendage morphogenesisGO:00351073970.023
anatomical structure homeostasisGO:0060249970.023
inter male aggressive behaviorGO:0002121600.023
positive regulation of jun kinase activityGO:004350740.023
actin filament bundle assemblyGO:0051017260.023
defense response to gram negative bacteriumGO:0050829940.023
covalent chromatin modificationGO:00165691060.023
negative regulation of organelle organizationGO:0010639560.023
cellular response to chemical stimulusGO:00708871990.023
positive regulation of programmed cell deathGO:0043068620.023
Human
signal transduction by phosphorylationGO:00230141070.023
hindbrain developmentGO:003090220.022
nucleotide catabolic processGO:00091661090.022
Human Mouse
response to organophosphorusGO:004668320.022
protein heterooligomerizationGO:005129140.022
cortical cytoskeleton organizationGO:0030865290.022
imaginal disc derived appendage morphogenesisGO:00351143950.022
protein catabolic processGO:00301631010.022
regulation of phosphate metabolic processGO:00192202100.022
Human Mouse
purine nucleoside metabolic processGO:00422781270.022
Human Mouse
multi multicellular organism processGO:00447061230.022
organic hydroxy compound metabolic processGO:1901615830.021
regulation of cell motilityGO:2000145230.021
Human
establishment or maintenance of cell polarityGO:00071631670.021
ethanolamine containing compound metabolic processGO:004243940.021
positive regulation of cell deathGO:0010942690.021
Human
single organism cell adhesionGO:0098602470.021
Human
response to light stimulusGO:00094161240.021
ribonucleoside metabolic processGO:00091191270.021
Human Mouse
protein complex disassemblyGO:0043241360.021
regulation of mitosisGO:0007088560.021
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.021
heart contractionGO:0060047260.021
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.021
organic cyclic compound catabolic processGO:19013611680.021
Human Mouse
proteolysis involved in cellular protein catabolic processGO:0051603830.021
inorganic cation transmembrane transportGO:0098662610.021
regulation of immune system processGO:00026821760.021
regulation of response to stressGO:00801342000.020
regulation of cell proliferationGO:00421271630.020
purine containing compound catabolic processGO:00725231120.020
Human Mouse
positive regulation of developmental growthGO:0048639620.020
regulation of synaptic vesicle transportGO:1902803100.020
positive regulation of phosphorylationGO:0042327870.020
regulation of synaptic plasticityGO:0048167140.020
negative regulation of cell differentiationGO:00455961430.020
establishment of cell polarityGO:0030010400.020
cellular protein complex disassemblyGO:0043624350.020
cell migration involved in gastrulationGO:004207490.020
myotube cell developmentGO:001490430.020
rhythmic synaptic transmissionGO:006002420.020
response to extracellular stimulusGO:00099911160.020
immune system processGO:00023763470.020
Mouse
central nervous system developmentGO:00074172010.020
negative regulation of protein complex disassemblyGO:0043242230.020
body morphogenesisGO:001017120.020
telencephalon developmentGO:002153720.020
generation of precursor metabolites and energyGO:0006091420.020
calcium ion homeostasisGO:0055074230.020
mitotic cell cycle phase transitionGO:00447721380.020
metal ion homeostasisGO:0055065440.019
cellular macromolecule catabolic processGO:00442651360.019
imaginal disc derived wing morphogenesisGO:00074763370.019
negative regulation of homeostatic processGO:003284520.019
wing disc morphogenesisGO:00074723440.019
oxidation reduction processGO:00551141230.019
cell growthGO:00160491080.019
regulation of neurotransmitter transportGO:0051588140.019
positive regulation of synaptic vesicle endocytosisGO:190024440.019
tripartite regional subdivisionGO:00073511030.019
regulation of heart rateGO:0002027110.019
cytoskeleton dependent intracellular transportGO:0030705440.019
response to hexoseGO:000974630.019
positive regulation of neurotransmitter secretionGO:000195620.019
regulation of immune responseGO:00507761180.019
cellular response to organic substanceGO:00713101320.019
determination of adult lifespanGO:00083401370.019
golgi organizationGO:0007030660.018
rna processingGO:00063961470.018
sensory perception of mechanical stimulusGO:0050954720.018
positive regulation of protein metabolic processGO:00512471280.018
regulation of system processGO:0044057360.018
protein localizationGO:00081042840.018
regulation of gene expression epigeneticGO:00400291280.018
exocrine system developmentGO:00352721620.018
reproductive behaviorGO:00190981220.018
multi organism behaviorGO:00517051750.018
vesicle fusionGO:0006906190.018
cell fate determinationGO:0001709910.018
dorsal ventral pattern formationGO:00099531330.018
negative regulation of protein depolymerizationGO:1901880230.018
protein maturationGO:0051604710.018
cytoskeleton dependent cytokinesisGO:0061640810.017
heart developmentGO:0007507820.017
protein localization to plasma membraneGO:0072659130.017
regulation of cellular amino acid metabolic processGO:000652100.017
organophosphate catabolic processGO:00464341120.017
Human Mouse
regulation of blood circulationGO:1903522210.017
response to temperature stimulusGO:00092661060.017
cellular macromolecular complex assemblyGO:00346221530.017
response to lipopolysaccharideGO:003249640.017
regulation of neuronal synaptic plasticityGO:004816880.017

rtGEF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.145
cardiovascular system diseaseDOID:128700.069
vascular diseaseDOID:17800.069
disease of cellular proliferationDOID:1456600.063
hypertensionDOID:1076300.032
artery diseaseDOID:005082800.032
cancerDOID:16200.028
organ system cancerDOID:005068600.028
nervous system diseaseDOID:86300.027
essential hypertensionDOID:1082500.024
inherited metabolic disorderDOID:65500.022
disease of metabolismDOID:001466700.022
central nervous system diseaseDOID:33100.019