IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG7946 (Dmel_CG7946)

CG7946 gene product from transcript CG7946-RA

(Aliases: Dmel\CG7946)

FLYBASE: FBgn0039743
Entrez: 43576
UniProtKB: Q9VAA9

Process Predictions
Disease Predictions

CG7946 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of rna metabolic process	GO:0051254	271	0.338	Human
positive regulation of biosynthetic process	GO:0009891	316	0.205	Human
positive regulation of macromolecule metabolic process	GO:0010604	405	0.201	Human
chromosome organization	GO:0051276	360	0.164
cellular protein modification process	GO:0006464	438	0.159
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.152	Human
regulation of multicellular organismal development	GO:2000026	414	0.131
histone modification	GO:0016570	106	0.130
covalent chromatin modification	GO:0016569	106	0.117
protein modification process	GO:0036211	438	0.107
cell proliferation	GO:0008283	299	0.099
organic substance catabolic process	GO:1901575	308	0.095
chromatin modification	GO:0016568	147	0.094
embryonic morphogenesis	GO:0048598	206	0.090
protein dna complex subunit organization	GO:0071824	86	0.084
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.084	Human
negative regulation of gene expression	GO:0010629	387	0.083	Human
organic acid metabolic process	GO:0006082	103	0.080
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.075	Human
embryo development ending in birth or egg hatching	GO:0009792	152	0.071
negative regulation of cellular metabolic process	GO:0031324	382	0.070	Human
small molecule metabolic process	GO:0044281	305	0.069
regulation of protein metabolic process	GO:0051246	256	0.068
negative regulation of biosynthetic process	GO:0009890	277	0.068	Human
positive regulation of transcription dna templated	GO:0045893	266	0.068	Human
regulation of cell differentiation	GO:0045595	302	0.063
chromatin organization	GO:0006325	207	0.062
meiotic cell cycle	GO:0051321	171	0.059
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.055	Human
regulation of catabolic process	GO:0009894	170	0.053
positive regulation of gene expression	GO:0010628	290	0.052	Human
organelle fission	GO:0048285	340	0.050
catabolic process	GO:0009056	409	0.050
morphogenesis of an epithelium	GO:0002009	276	0.050
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.049	Human
regulation of cellular protein metabolic process	GO:0032268	243	0.046
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.045	Human
regulation of cell proliferation	GO:0042127	163	0.045
negative regulation of transcription dna templated	GO:0045892	237	0.043	Human
regulation of cellular ketone metabolic process	GO:0010565	3	0.043
response to organic substance	GO:0010033	284	0.042
nuclear division	GO:0000280	332	0.042
internal peptidyl lysine acetylation	GO:0018393	38	0.042
neurological system process	GO:0050877	358	0.041
cellular catabolic process	GO:0044248	372	0.041
ras protein signal transduction	GO:0007265	88	0.040
tube development	GO:0035295	244	0.040
positive regulation of cellular biosynthetic process	GO:0031328	316	0.040	Human
regulation of cell cycle process	GO:0010564	181	0.039
epithelial cell development	GO:0002064	274	0.039
ovarian follicle cell development	GO:0030707	248	0.039
regulation of ras protein signal transduction	GO:0046578	93	0.037
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.037
positive regulation of catalytic activity	GO:0043085	118	0.037
determination of adult lifespan	GO:0008340	137	0.036
organonitrogen compound metabolic process	GO:1901564	318	0.035
cytoplasmic transport	GO:0016482	130	0.035
organic substance transport	GO:0071702	257	0.034
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.034	Human
regulation of cell death	GO:0010941	173	0.033
protein localization	GO:0008104	284	0.032
tube morphogenesis	GO:0035239	191	0.031
single organism intracellular transport	GO:1902582	207	0.030
transcription from rna polymerase ii promoter	GO:0006366	368	0.030	Human
gene silencing	GO:0016458	138	0.029
peptidyl amino acid modification	GO:0018193	105	0.029
small gtpase mediated signal transduction	GO:0007264	88	0.029
positive regulation of cellular amine metabolic process	GO:0033240	0	0.029
establishment of protein localization	GO:0045184	163	0.029
protein transport	GO:0015031	155	0.028
chromatin remodeling	GO:0006338	72	0.028
regulation of transport	GO:0051049	181	0.028
cellularization	GO:0007349	90	0.028
regulation of catalytic activity	GO:0050790	185	0.028
regulation of mitotic cell cycle	GO:0007346	190	0.028
aging	GO:0007568	143	0.027
meiotic nuclear division	GO:0007126	151	0.027
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.026
positive regulation of rna biosynthetic process	GO:1902680	266	0.026	Human
oxoacid metabolic process	GO:0043436	103	0.026
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.025	Human
positive regulation of cell death	GO:0010942	69	0.025
peptidyl lysine modification	GO:0018205	57	0.025
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.025	Human
protein catabolic process	GO:0030163	101	0.024
response to abiotic stimulus	GO:0009628	341	0.024
localization of cell	GO:0051674	257	0.024
regulation of cellular amine metabolic process	GO:0033238	3	0.021
intracellular transport	GO:0046907	228	0.021
imaginal disc derived wing morphogenesis	GO:0007476	337	0.021
negative regulation of cellular biosynthetic process	GO:0031327	277	0.021	Human
regulation of molecular function	GO:0065009	217	0.021
protein localization to nucleus	GO:0034504	55	0.020
carboxylic acid metabolic process	GO:0019752	92	0.020
appendage morphogenesis	GO:0035107	397	0.020
hematopoietic or lymphoid organ development	GO:0048534	57	0.020
single organism behavior	GO:0044708	391	0.019
aromatic compound catabolic process	GO:0019439	166	0.019
body morphogenesis	GO:0010171	2	0.019
nucleus organization	GO:0006997	45	0.019
epithelial cell differentiation	GO:0030855	322	0.019
regulation of protein catabolic process	GO:0042176	55	0.018
digestive tract morphogenesis	GO:0048546	127	0.018
macromolecule catabolic process	GO:0009057	161	0.018
urogenital system development	GO:0001655	72	0.018
histone methylation	GO:0016571	40	0.018
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.018
response to nitrogen compound	GO:1901698	90	0.017
positive regulation of apoptotic process	GO:0043065	47	0.017
anatomical structure homeostasis	GO:0060249	97	0.017
proteolysis	GO:0006508	192	0.017
positive regulation of signal transduction	GO:0009967	223	0.017
regulation of dna metabolic process	GO:0051052	34	0.017
negative regulation of rna metabolic process	GO:0051253	251	0.017	Human
organic cyclic compound catabolic process	GO:1901361	168	0.017
negative regulation of rna biosynthetic process	GO:1902679	240	0.017	Human
post embryonic appendage morphogenesis	GO:0035120	385	0.017
cell migration	GO:0016477	238	0.017
regulation of cellular localization	GO:0060341	136	0.016
positive regulation of programmed cell death	GO:0043068	62	0.016
immune system process	GO:0002376	347	0.016
heterocycle catabolic process	GO:0046700	166	0.016
spinal cord development	GO:0021510	1	0.016
regulation of cell cycle	GO:0051726	291	0.016
immune system development	GO:0002520	57	0.016
vesicle mediated transport	GO:0016192	381	0.016
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.016
protein acetylation	GO:0006473	39	0.016
regulation of phosphate metabolic process	GO:0019220	210	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
regulation of proteolysis	GO:0030162	87	0.016
regulation of mapk cascade	GO:0043408	92	0.015
regulation of localization	GO:0032879	275	0.015
protein alkylation	GO:0008213	43	0.015
single organism cellular localization	GO:1902580	180	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015	Human
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.015
columnar cuboidal epithelial cell development	GO:0002066	249	0.015
establishment of localization in cell	GO:0051649	402	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.014
cellular response to chemical stimulus	GO:0070887	199	0.014
regulation of programmed cell death	GO:0043067	152	0.014
response to radiation	GO:0009314	155	0.014
posttranscriptional gene silencing	GO:0016441	46	0.014
cellular macromolecule localization	GO:0070727	220	0.014
rna interference	GO:0016246	27	0.014
protein localization to organelle	GO:0033365	82	0.014
eye development	GO:0001654	323	0.014
response to endogenous stimulus	GO:0009719	119	0.013
posttranscriptional gene silencing by rna	GO:0035194	45	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
regulation of anatomical structure morphogenesis	GO:0022603	242	0.013
cellular amino acid metabolic process	GO:0006520	61	0.013
compound eye development	GO:0048749	307	0.013
dna metabolic process	GO:0006259	227	0.013
negative regulation of intrinsic apoptotic signaling pathway	GO:2001243	1	0.013
terminal button organization	GO:0072553	19	0.013
cytoskeleton dependent cytokinesis	GO:0061640	81	0.013
regulation of developmental growth	GO:0048638	174	0.013
regulation of cellular amino acid metabolic process	GO:0006521	0	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.013	Human
cell death	GO:0008219	279	0.013
response to organic cyclic compound	GO:0014070	89	0.012
hemopoiesis	GO:0030097	46	0.012
centrosome organization	GO:0051297	163	0.012
positive regulation of hydrolase activity	GO:0051345	78	0.012
protein ubiquitination	GO:0016567	70	0.012
positive regulation of cell communication	GO:0010647	250	0.012
developmental growth	GO:0048589	280	0.012
positive regulation of nucleotide catabolic process	GO:0030813	46	0.012
nucleoside catabolic process	GO:0009164	112	0.012
reproductive structure development	GO:0048608	74	0.012
negative regulation of protein metabolic process	GO:0051248	85	0.012
histone lysine methylation	GO:0034968	32	0.012
regulation of meiosis	GO:0040020	3	0.012
gastrulation with mouth forming first	GO:0001703	36	0.012
developmental maturation	GO:0021700	172	0.012
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
gonad development	GO:0008406	50	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
neuroblast proliferation	GO:0007405	74	0.011
muscle structure development	GO:0061061	224	0.011
peptidyl lysine methylation	GO:0018022	16	0.011
imaginal disc derived appendage development	GO:0048737	399	0.011
methylation	GO:0032259	47	0.011
wing disc morphogenesis	GO:0007472	344	0.011
cellular protein catabolic process	GO:0044257	83	0.011
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.011
cell division	GO:0051301	248	0.011
histone acetylation	GO:0016573	38	0.011
cellular amine metabolic process	GO:0044106	12	0.011
phagocytosis	GO:0006909	215	0.011
negative regulation of molecular function	GO:0044092	51	0.010
organophosphate metabolic process	GO:0019637	195	0.010
organonitrogen compound catabolic process	GO:1901565	128	0.010
ribonucleotide metabolic process	GO:0009259	145	0.010
ribonucleotide catabolic process	GO:0009261	109	0.010
cellular chemical homeostasis	GO:0055082	40	0.010

CG7946 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.119
nervous system disease	DOID:863	0.034
central nervous system disease	DOID:331	0.011
disease of cellular proliferation	DOID:14566	0.011

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