Drosophila melanogaster

193 known processes

bun (Dmel_CG42281)

bunched

(Aliases: BunA,1550,shs,CG42281,l(2)rI043,TSC-22,Dmel\CG42281,l(2)02687,l(2)06475,CG5461,l(2)00255,EP(2)0488,Bun,CG31857,l(2)k02903,l(2)05479,Dmel_CG5461,Tsc22,Dmel_CG31857)

bun biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
eye morphogenesisGO:00485922600.894
compound eye photoreceptor cell differentiationGO:00017511400.862
eggshell chorion assemblyGO:0007306660.806
sensory organ morphogenesisGO:00905962600.773
small gtpase mediated signal transductionGO:0007264880.743
regulation of growthGO:00400082330.730
ovarian follicle cell developmentGO:00307072480.706
actin filament organizationGO:00070151260.675
segmentationGO:00352822070.649
compound eye morphogenesisGO:00017452490.577
ras protein signal transductionGO:0007265880.565
epithelial cell developmentGO:00020642740.555
regulation of cellular protein metabolic processGO:00322682430.522
epithelial cell differentiationGO:00308553220.502
compound eye developmentGO:00487493070.499
actin filament based processGO:00300292200.497
ovarian follicle cell migrationGO:00072971210.479
regionalizationGO:00030024160.469
negative regulation of developmental processGO:00510932010.458
response to abiotic stimulusGO:00096283410.451
embryonic development via the syncytial blastodermGO:00017001480.430
post embryonic appendage morphogenesisGO:00351203850.423
positive regulation of protein metabolic processGO:00512471280.417
lipid metabolic processGO:00066291210.415
mitotic cell cycle phase transitionGO:00447721380.395
response to organic substanceGO:00100332840.387
regulation of small gtpase mediated signal transductionGO:0051056930.352
phototaxisGO:0042331210.341
regulation of ras protein signal transductionGO:0046578930.340
intracellular signal transductionGO:00355563000.331
imaginal disc derived appendage morphogenesisGO:00351143950.325
axis specificationGO:00097981670.317
actin cytoskeleton organizationGO:00300362060.307
negative regulation of nucleic acid templated transcriptionGO:19035072400.296
negative regulation of epithelial cell proliferationGO:005068040.274
regulation of intracellular signal transductionGO:19025312360.270
regulation of developmental growthGO:00486381740.251
embryonic pattern specificationGO:00098801740.246
regulation of cytoskeleton organizationGO:0051493890.246
compound eye photoreceptor developmentGO:0042051780.244
regulation of cell differentiationGO:00455953020.227
cellular response to chemical stimulusGO:00708871990.222
columnar cuboidal epithelial cell differentiationGO:00020652560.214
columnar cuboidal epithelial cell developmentGO:00020662490.204
single organism behaviorGO:00447083910.203
positive regulation of cellular biosynthetic processGO:00313283160.186
r7 cell fate commitmentGO:0007465120.179
macromolecular complex assemblyGO:00650032560.172
negative regulation of multicellular organismal processGO:00512411420.171
tube morphogenesisGO:00352391910.169
single organism cellular localizationGO:19025801800.164
positive regulation of signal transductionGO:00099672230.163
endocytosisGO:00068973100.158
morphogenesis of a polarized epitheliumGO:0001738930.157
establishment of localization in cellGO:00516494020.153
phagocytosisGO:00069092150.149
protein localizationGO:00081042840.148
positive regulation of cellular protein metabolic processGO:00322701180.146
cellular response to organic substanceGO:00713101320.146
growthGO:00400073590.143
negative regulation of cell communicationGO:00106482230.142
head developmentGO:00603221350.137
synaptic growth at neuromuscular junctionGO:00511241190.137
mushroom body developmentGO:0016319700.135
cellular lipid metabolic processGO:0044255830.135
photoreceptor cell differentiationGO:00465301700.128
establishment or maintenance of apical basal cell polarityGO:0035088340.124
cell cycle g1 s phase transitionGO:0044843310.124
response to endogenous stimulusGO:00097191190.124
regulation of phosphatidylinositol 3 kinase activityGO:004355120.123
catabolic processGO:00090564090.120
regulation of protein metabolic processGO:00512462560.113
carbohydrate derivative metabolic processGO:19011352170.113
photoreceptor cell developmentGO:0042461960.111
gland developmentGO:00487321910.108
cellular macromolecule localizationGO:00707272200.100
organic substance catabolic processGO:19015753080.097
intracellular protein transportGO:00068861040.096
positive regulation of response to stimulusGO:00485843230.095
regulation of apoptotic processGO:00429811300.095
single organism intracellular transportGO:19025822070.091
brain developmentGO:00074201200.090
regulation of cell divisionGO:0051302720.089
positive regulation of immune responseGO:0050778630.087
positive regulation of translationGO:0045727120.085
positive regulation of erk1 and erk2 cascadeGO:0070374360.084
pole plasm assemblyGO:0007315610.084
morphogenesis of follicular epitheliumGO:0016333360.083
positive regulation of ras protein signal transductionGO:0046579430.083
negative regulation of cell cycle phase transitionGO:19019881030.082
imaginal disc derived appendage developmentGO:00487373990.081
cellular macromolecular complex assemblyGO:00346221530.081
negative regulation of signalingGO:00230572190.080
oocyte differentiationGO:00099941450.080
positive regulation of phosphate metabolic processGO:00459371390.080
positive regulation of signalingGO:00230562430.079
regulation of cellular component biogenesisGO:00440872010.077
organophosphate metabolic processGO:00196371950.076
establishment or maintenance of cell polarityGO:00071631670.076
negative regulation of growthGO:0045926840.076
phosphorylationGO:00163102940.075
regulation of phosphorylationGO:00423251470.073
imaginal disc derived wing morphogenesisGO:00074763370.072
proteasomal protein catabolic processGO:0010498590.072
cellular catabolic processGO:00442483720.072
response to ketoneGO:1901654340.072
protein complex assemblyGO:00064612000.071
blastoderm segmentationGO:00073501590.069
regulation of cellular component sizeGO:0032535980.066
lipid catabolic processGO:0016042210.066
leg disc morphogenesisGO:0007478800.066
regulation of establishment of protein localizationGO:0070201610.064
embryonic axis specificationGO:00005781070.064
response to decreased oxygen levelsGO:0036293580.064
positive regulation of cellular response to insulin stimulusGO:190007840.061
positive regulation of insulin receptor signaling pathwayGO:004662830.061
cellular response to endogenous stimulusGO:0071495800.060
single organism catabolic processGO:00447122280.060
regulation of phosphate metabolic processGO:00192202100.059
regulation of actin cytoskeleton organizationGO:0032956420.059
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.058
single organism biosynthetic processGO:00447112060.057
negative regulation of cell differentiationGO:00455961430.055
regulation of cell growthGO:0001558430.054
regulation of tor signalingGO:0032006210.054
compound eye retinal cell programmed cell deathGO:0046667230.054
leg disc developmentGO:0035218920.054
nuclear transportGO:0051169720.053
small molecule metabolic processGO:00442813050.052
eye photoreceptor cell developmentGO:0042462810.051
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.051
central nervous system developmentGO:00074172010.051
macroautophagyGO:0016236420.051
tor signalingGO:0031929320.050
protein localization to nucleusGO:0034504550.050
organonitrogen compound catabolic processGO:19015651280.050
organic cyclic compound catabolic processGO:19013611680.050
neuromuscular junction developmentGO:00075281490.049
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.049
regulation of multicellular organism growthGO:0040014400.049
posttranscriptional regulation of gene expressionGO:00106081450.049
chorion containing eggshell formationGO:00073041050.048
establishment of tissue polarityGO:0007164870.048
cellular protein complex assemblyGO:0043623710.047
synapse assemblyGO:00074161430.047
positive regulation of mapk cascadeGO:0043410630.046
vesicle mediated transportGO:00161923810.046
compound eye photoreceptor fate commitmentGO:0001752360.046
establishment of planar polarityGO:0001736870.046
heterocycle catabolic processGO:00467001660.046
regulation of cell cycle phase transitionGO:19019871300.045
border follicle cell migrationGO:00072981130.045
eye developmentGO:00016543230.045
adherens junction organizationGO:0034332270.044
regulation of cell cycle processGO:00105641810.044
regulation of cell cycleGO:00517262910.043
negative regulation of cell cycleGO:00457861160.043
oocyte microtubule cytoskeleton polarizationGO:0008103220.043
nucleoside catabolic processGO:00091641120.043
ameboidal type cell migrationGO:00016671510.043
biological adhesionGO:00226101380.042
response to oxygen containing compoundGO:19017002000.042
regulation of translationGO:0006417560.042
enteroendocrine cell differentiationGO:003588310.041
regulation of cellular catabolic processGO:00313291570.040
mitotic nuclear divisionGO:00070672130.040
negative regulation of nucleobase containing compound metabolic processGO:00459342610.040
regulation of defense responseGO:00313471020.040
regulation of insulin like growth factor receptor signaling pathwayGO:004356730.039
mitotic sister chromatid segregationGO:0000070870.039
appendage developmentGO:00487364010.039
regulation of neuroblast proliferationGO:1902692340.039
agingGO:00075681430.039
protein catabolic processGO:00301631010.039
macromolecule catabolic processGO:00090571610.038
spermatogenesisGO:00072832000.038
intrinsic apoptotic signaling pathwayGO:0097193160.037
positive regulation of cell deathGO:0010942690.037
developmental growthGO:00485892800.037
positive regulation of phosphorus metabolic processGO:00105621390.036
transposition rna mediatedGO:003219730.036
ion transportGO:00068111450.036
response to hypoxiaGO:0001666530.036
epithelial cell migrationGO:00106311480.035
positive regulation of intracellular signal transductionGO:19025331160.034
exocrine system developmentGO:00352721620.034
response to oxygen levelsGO:0070482590.034
oxidation reduction processGO:00551141230.033
regulation of cellular response to insulin stimulusGO:1900076170.032
developmental programmed cell deathGO:00106231380.032
stem cell differentiationGO:00488631170.032
dorsal ventral axis specificationGO:0009950660.032
regulation of immune system processGO:00026821760.031
glycosyl compound metabolic processGO:19016571270.031
regulation of cell developmentGO:00602842150.031
nuclear divisionGO:00002803320.031
dorsal appendage formationGO:0046843470.030
photoreceptor cell fate commitmentGO:0046552410.030
regulation of actin filament based processGO:0032970420.030
cell growthGO:00160491080.030
cell divisionGO:00513012480.030
negative regulation of response to stimulusGO:00485852580.029
carbohydrate derivative biosynthetic processGO:1901137850.029
digestive system developmentGO:00551231490.029
lipid storageGO:0019915380.029
mapk cascadeGO:00001651070.029
ribonucleotide catabolic processGO:00092611090.029
immune responseGO:00069552460.029
regulation of mapk cascadeGO:0043408920.029
establishment of ommatidial planar polarityGO:0042067490.029
eye photoreceptor cell fate commitmentGO:0042706370.028
intracellular transportGO:00469072280.028
negative regulation of response to extracellular stimulusGO:003210560.028
regulation of cellular localizationGO:00603411360.028
regulation of insulin receptor signaling pathwayGO:0046626170.028
cellular response to radiationGO:0071478520.028
positive regulation of biosynthetic processGO:00098913160.027
cellular macromolecule catabolic processGO:00442651360.027
positive regulation of macromolecule biosynthetic processGO:00105572830.027
organonitrogen compound metabolic processGO:19015643180.027
modification dependent protein catabolic processGO:0019941780.027
immune system processGO:00023763470.027
regulation of multicellular organismal developmentGO:20000264140.027
cellular response to nutrient levelsGO:0031669620.027
entry into diapauseGO:005511510.027
positive regulation of macromolecule metabolic processGO:00106044050.026
olfactory behaviorGO:0042048970.026
regulation of localizationGO:00328792750.025
regulation of catalytic activityGO:00507901850.025
positive regulation of cell communicationGO:00106472500.025
regulation of cytoplasmic transportGO:1903649470.025
response to ecdysoneGO:0035075340.025
cellular lipid catabolic processGO:0044242160.025
mrna processingGO:00063971040.025
small molecule biosynthetic processGO:0044283370.025
proteolysis involved in cellular protein catabolic processGO:0051603830.024
ribonucleoside metabolic processGO:00091191270.024
regulation of protein localizationGO:0032880760.024
protein modification processGO:00362114380.024
regulation of mitotic cell cycle phase transitionGO:19019901300.024
germarium derived female germ line cyst encapsulationGO:003070880.024
negative regulation of cellular metabolic processGO:00313243820.024
positive regulation of cell cycleGO:0045787430.024
regulation of catabolic processGO:00098941700.023
regulation of phosphatase activityGO:001092130.023
regulation of stem cell differentiationGO:2000736140.023
wing disc morphogenesisGO:00074723440.023
regulation of protein modification processGO:00313991120.023
organic substance transportGO:00717022570.023
positive regulation of cell cycle processGO:0090068280.023
apoptotic processGO:00069151590.023
rho protein signal transductionGO:0007266140.023
cellular response to dna damage stimulusGO:00069742230.023
anterior posterior pattern specificationGO:00099521360.022
regulation of cell deathGO:00109411730.022
protein transportGO:00150311550.022
positive regulation of small gtpase mediated signal transductionGO:0051057430.022
regulation of rho protein signal transductionGO:0035023200.022
regulation of protein complex assemblyGO:0043254420.022
positive regulation of developmental growthGO:0048639620.022
cell cycle phase transitionGO:00447701400.022
metal ion transportGO:0030001740.022
cell proliferationGO:00082832990.021
deathGO:00162652840.021
r8 cell fate specificationGO:004546450.021
protein polymerizationGO:0051258420.021
hemocyte differentiationGO:0042386380.021
appendage morphogenesisGO:00351073970.021
lipid biosynthetic processGO:0008610460.021
nuclear importGO:0051170510.021
cell motilityGO:00488702510.021
tube developmentGO:00352952440.021
cell cycle arrestGO:000705040.021
protein complex biogenesisGO:00702712010.020
body morphogenesisGO:001017120.020
response to temperature stimulusGO:00092661060.020
retina development in camera type eyeGO:006004140.020
chitin based cuticle developmentGO:0040003490.020
g1 s transition of mitotic cell cycleGO:0000082310.020
cytokinesisGO:0000910900.020
cytoplasm organizationGO:0007028640.020
response to peptideGO:1901652290.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.019
negative regulation of mitotic cell cycle phase transitionGO:19019911030.019
chitin based embryonic cuticle biosynthetic processGO:0008362160.019
regulation of phosphorus metabolic processGO:00511742100.019
negative regulation of photoreceptor cell differentiationGO:004653380.019
tripartite regional subdivisionGO:00073511030.019
purine nucleoside catabolic processGO:00061521120.019
maintenance of protein locationGO:0045185280.019
erk1 and erk2 cascadeGO:0070371390.019
protein targetingGO:0006605640.019
metal ion homeostasisGO:0055065440.019
negative regulation of developmental growthGO:0048640640.019
imaginal disc derived leg morphogenesisGO:0007480800.019
positive regulation of growthGO:0045927750.019
ribonucleotide biosynthetic processGO:0009260280.019
epithelium migrationGO:00901321480.019
regulation of cardioblast differentiationGO:005189090.019
negative regulation of intracellular signal transductionGO:1902532570.018
regulation of protein phosphorylationGO:0001932640.018
nucleotide metabolic processGO:00091171610.018
carboxylic acid metabolic processGO:0019752920.018
secretion by cellGO:00329401010.018
germ line stem cell maintenanceGO:0030718500.018
negative regulation of cell cycle processGO:00109481090.018
regulation of programmed cell deathGO:00430671520.018
regulation of organelle organizationGO:00330431960.018
positive regulation of transportGO:0051050920.018
cell cell junction organizationGO:0045216550.017
telomere organizationGO:0032200210.017
head involutionGO:0008258350.017
stress activated mapk cascadeGO:0051403520.017
microtubule polymerization or depolymerizationGO:0031109390.017
regulation of response to stressGO:00801342000.017
establishment or maintenance of epithelial cell apical basal polarityGO:0045197240.017
convergent extension involved in gastrulationGO:006002720.016
negative regulation of catabolic processGO:0009895360.016
cell deathGO:00082192790.016
cation homeostasisGO:0055080510.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
hemocyte migrationGO:0035099190.016
ovarian follicle cell stalk formationGO:0030713170.016
cellular protein localizationGO:00346131600.016
regulation of mitotic cell cycleGO:00073461900.016
organelle inheritanceGO:004830820.016
protein complex disassemblyGO:0043241360.016
dorsal ventral axis specification ovarian follicular epitheliumGO:0008069130.016
nucleocytoplasmic transportGO:0006913720.015
regulation of hydrolase activityGO:0051336970.015
regulation of actin filament polymerizationGO:0030833250.015
cell matrix adhesionGO:000716060.015
regulation of cell cycle g1 s phase transitionGO:1902806230.015
primary spermatocyte growthGO:000728550.015
glycosyl compound catabolic processGO:19016581120.015
female germ line stem cell maintenanceGO:003609980.015
homeostatic processGO:00425921990.015
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.015
nucleobase containing compound catabolic processGO:00346551650.015
rac protein signal transductionGO:001660130.015
protein targeting to nucleusGO:0044744510.015
positive regulation of phosphorylationGO:0042327870.015
regulation of protein transportGO:0051223570.015
establishment of protein localizationGO:00451841630.014
oocyte developmentGO:00485991240.014
purine containing compound catabolic processGO:00725231120.014
response to insulinGO:0032868290.014
anterior posterior axis specificationGO:00099481090.014
chemical homeostasisGO:0048878920.014
maintenance of locationGO:0051235730.014
imaginal disc pattern formationGO:0007447910.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
negative regulation of signal transductionGO:00099682060.014
cellular nitrogen compound catabolic processGO:00442701650.014
negative regulation of synapse assemblyGO:0051964390.014
negative regulation of cell proliferationGO:0008285690.014
positive regulation of apoptotic signaling pathwayGO:200123540.014
cell substrate adhesionGO:0031589100.014
insulin receptor signaling pathwayGO:0008286250.014
regulation of gene silencingGO:0060968630.013
mitotic dna integrity checkpointGO:0044774750.013
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.013
protein import into nucleusGO:0006606510.013
regulation of malpighian tubule diameterGO:003529730.013
histolysisGO:00075591020.013
germarium derived egg chamber formationGO:00072931010.013
positive regulation of hydrolase activityGO:0051345780.013
negative regulation of rna metabolic processGO:00512532510.013
modification dependent macromolecule catabolic processGO:0043632790.013
pole plasm mrna localizationGO:0019094490.013
carbohydrate derivative catabolic processGO:19011361180.013
neurological system processGO:00508773580.013
gtp catabolic processGO:0006184720.013
female sex differentiationGO:0046660200.013
integrin mediated signaling pathwayGO:000722930.013
positive regulation of transcription dna templatedGO:00458932660.013
nucleoside phosphate metabolic processGO:00067531620.013
positive regulation of r7 cell differentiationGO:004567870.013
positive regulation of gene expressionGO:00106282900.012
ribonucleoside catabolic processGO:00424541120.012
spermatid developmentGO:0007286980.012
regulation of gtpase activityGO:0043087440.012
chromosome organizationGO:00512763600.012
cellular carbohydrate metabolic processGO:0044262220.012
cellular response to decreased oxygen levelsGO:0036294300.012
negative regulation of nervous system developmentGO:0051961920.012
regulation of protein catabolic processGO:0042176550.012
organophosphate biosynthetic processGO:0090407460.012
regulation of intracellular protein transportGO:0033157460.012
regulation of purine nucleotide metabolic processGO:1900542620.012
innate immune responseGO:00450871440.012
regulation of multi organism processGO:00439001310.012
dna integrity checkpointGO:0031570810.012
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.012
regulation of neuron projection developmentGO:0010975690.012
regulation of imaginal disc derived wing sizeGO:0044719200.012
purine nucleotide catabolic processGO:00061951090.012
regulation of viral genome replicationGO:004506940.012
protein phosphorylationGO:00064681690.012
negative regulation of macroautophagyGO:001624260.012
cell agingGO:000756920.012
response to hormoneGO:0009725450.012
retina morphogenesis in camera type eyeGO:006004220.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
localization of cellGO:00516742570.012
negative regulation of immune system processGO:0002683500.011
imaginal disc eversionGO:000756140.011
stem cell divisionGO:0017145690.011
eggshell formationGO:00307031050.011
response to uvGO:0009411240.011
macromolecular complex disassemblyGO:0032984370.011
establishment of imaginal disc derived wing hair orientationGO:0001737240.011
regulation of response to external stimulusGO:00321011150.011
regulation of epithelial cell proliferationGO:005067840.011
nucleobase containing small molecule metabolic processGO:00550861740.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
positive regulation of immune effector processGO:0002699280.011
negative regulation of mitotic cell cycleGO:00459301090.011
nucleoside phosphate catabolic processGO:19012921100.011
carbohydrate metabolic processGO:0005975820.011
response to inorganic substanceGO:0010035440.011
endomembrane system organizationGO:00102561190.011
torc1 signalingGO:0038202120.011
larval developmentGO:00021641040.011
neuroblast proliferationGO:0007405740.011
positive regulation of cellular component organizationGO:00511301560.011
response to organic cyclic compoundGO:0014070890.011
regulation of erk1 and erk2 cascadeGO:0070372390.011
ribose phosphate metabolic processGO:00196931450.011
negative regulation of gene expressionGO:00106293870.010
cellular amino acid metabolic processGO:0006520610.010
positive regulation of apoptotic processGO:0043065470.010
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
cytoplasmic transportGO:00164821300.010
germarium derived oocyte fate determinationGO:0007294260.010
programmed cell deathGO:00125012570.010
positive regulation of stress fiber assemblyGO:005149630.010
positive regulation of organelle organizationGO:0010638650.010
regulation of molecular functionGO:00650092170.010
establishment or maintenance of polarity of embryonic epitheliumGO:001633230.010

bun disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013