Drosophila melanogaster

183 known processes

polo (Dmel_CG12306)

CG12306 gene product from transcript CG12306-RA

(Aliases: Dmel\CG12306,l(3)77Aa,Polo,POLO/PLK1,CG12306,l(3)S025604,0256/04,l(3)S132408,l(3)01673,POLO,anon-WO0172774.3,1324/08)

polo biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic cell cycle processGO:19030461321.000
organelle fissionGO:00482853401.000
nuclear divisionGO:00002803321.000
meiotic cell cycleGO:00513211711.000
chromosome organizationGO:00512763601.000
Human Yeast
meiotic nuclear divisionGO:00071261511.000
meiosis iGO:0007127591.000
Yeast Worm
meiotic spindle organizationGO:0000212361.000
chromosome segregationGO:00070591570.999
Human Yeast Worm
spermatogenesisGO:00072832000.999
cell divisionGO:00513012480.999
spindle organizationGO:00070512530.999
male meiosisGO:0007140520.999
mitotic sister chromatid separationGO:0051306300.998
Human
organelle assemblyGO:00709251980.995
spindle assembly involved in meiosisGO:0090306200.995
cytokinesisGO:0000910900.991
male gamete generationGO:00482322010.990
mitotic nuclear divisionGO:00070672130.987
mitotic spindle organizationGO:00070522200.984
development of primary sexual characteristicsGO:0045137500.984
Worm
dna conformation changeGO:00711031050.978
regulation of mitotic cell cycleGO:00073461900.977
Human
gonad developmentGO:0008406500.975
Worm
regulation of neurogenesisGO:00507671580.971
microtubule organizing center organizationGO:00310231680.968
spermatid differentiationGO:00485151140.964
single fertilizationGO:0007338240.944
regulation of cell cycle phase transitionGO:19019871300.933
Human
regulation of cell cycleGO:00517262910.923
Human Yeast Worm
centrosome duplicationGO:00512981210.920
cell cycle phase transitionGO:00447701400.914
Human
cytoskeleton dependent cytokinesisGO:0061640810.914
oocyte maturationGO:000155630.895
reproductive system developmentGO:0061458740.881
Worm
cellular component assembly involved in morphogenesisGO:00109271510.872
neuroblast proliferationGO:0007405740.869
reproductive structure developmentGO:0048608740.859
Worm
meiotic chromosome segregationGO:0045132590.853
Yeast Worm
centrosome cycleGO:00070981370.841
Worm
chromosome separationGO:0051304420.830
Human Yeast
negative regulation of gene expressionGO:00106293870.830
Human
negative regulation of cell cycleGO:00457861160.829
Human
mitotic cell cycle phase transitionGO:00447721380.824
Human
regulation of microtubule based processGO:0032886490.824
Yeast
female meiotic divisionGO:0007143700.802
negative regulation of cellular biosynthetic processGO:00313272770.799
Human
spindle assembly involved in female meiosisGO:0007056140.791
regulation of cell cycle processGO:00105641810.791
Human Yeast Worm
regulation of organelle organizationGO:00330431960.789
Human Yeast Worm
mitotic cell cycle checkpointGO:0007093880.784
Human
negative regulation of macromolecule biosynthetic processGO:00105582700.773
Human
nucleus organizationGO:0006997450.769
positive regulation of protein metabolic processGO:00512471280.759
Human
sister chromatid segregationGO:0000819920.736
Human
protein modification processGO:00362114380.731
neural precursor cell proliferationGO:0061351750.730
regulation of mitosisGO:0007088560.720
Human
chromosome condensationGO:0030261410.713
spindle assembly involved in mitosisGO:0090307500.693
regulation of meiosisGO:004002030.687
Worm
centrosome organizationGO:00512971630.682
actomyosin structure organizationGO:0031032560.677
mitotic sister chromatid segregationGO:0000070870.675
Human
regulation of neuroblast proliferationGO:1902692340.673
regulation of growthGO:00400082330.668
cell deathGO:00082192790.665
Human Worm
meiosis iiGO:0007135230.663
cellular protein modification processGO:00064644380.642
body morphogenesisGO:001017120.640
regulation of protein metabolic processGO:00512462560.636
Human
mitotic spindle stabilizationGO:004314860.635
spindle assemblyGO:0051225800.629
sex differentiationGO:0007548810.616
Worm
regulation of multicellular organismal developmentGO:20000264140.614
negative regulation of biosynthetic processGO:00098902770.612
Human
phosphorylationGO:00163102940.605
negative regulation of rna biosynthetic processGO:19026792400.599
Human
stem cell maintenanceGO:0019827670.599
chromatin modificationGO:00165681470.595
spermatid developmentGO:0007286980.595
establishment of cell polarityGO:0030010400.582
positive regulation of macromolecule metabolic processGO:00106044050.571
Human
positive regulation of developmental processGO:00510941430.568
stem cell differentiationGO:00488631170.566
female meiosis iGO:000714480.564
regulation of cytoskeleton organizationGO:0051493890.545
Yeast
regulation of proteasomal protein catabolic processGO:0061136390.545
Human
embryo development ending in birth or egg hatchingGO:00097921520.542
Worm
positive regulation of cellular protein metabolic processGO:00322701180.542
Human
regulation of cell differentiationGO:00455953020.541
ubiquitin dependent protein catabolic processGO:0006511780.534
Human
cellular protein complex disassemblyGO:0043624350.521
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.504
Human
modification dependent protein catabolic processGO:0019941780.494
Human
regulation of mitotic spindle organizationGO:006023690.461
positive regulation of transcription dna templatedGO:00458932660.453
regulation of chromosome segregationGO:0051983320.445
Human
positive regulation of neurogenesisGO:0050769410.438
regulation of mitotic sister chromatid segregationGO:0033047280.426
Human
fertilizationGO:0009566260.417
cellular component disassemblyGO:0022411460.412
Yeast Worm
establishment of localization in cellGO:00516494020.398
regulation of cell proliferationGO:00421271630.395
chromatin organizationGO:00063252070.369
meiotic sister chromatid segregationGO:004514460.363
mitotic cytokinesisGO:0000281500.361
Human
regulation of metaphase anaphase transition of cell cycleGO:1902099260.356
Human
regulation of microtubule cytoskeleton organizationGO:0070507410.348
Yeast
regulation of developmental growthGO:00486381740.343
spindle stabilizationGO:0043146140.331
positive regulation of multicellular organismal processGO:00512401430.327
regulation of cell divisionGO:0051302720.327
Human Worm
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.326
Human
regulation of cell deathGO:00109411730.316
Human
embryonic morphogenesisGO:00485982060.316
asymmetric cell divisionGO:0008356370.316
tube developmentGO:00352952440.313
negative regulation of developmental processGO:00510932010.305
modification dependent macromolecule catabolic processGO:0043632790.305
Human
positive regulation of cell developmentGO:0010720610.304
regulation of mitotic cell cycle phase transitionGO:19019901300.293
Human
macromolecular complex disassemblyGO:0032984370.292
dendrite developmentGO:00163582040.280
stem cell divisionGO:0017145690.270
imaginal disc derived appendage morphogenesisGO:00351143950.266
protein complex biogenesisGO:00702712010.264
cystoblast divisionGO:0007282100.262
asymmetric stem cell divisionGO:0098722490.259
regulation of mitotic sister chromatid separationGO:0010965280.255
Human
cell migrationGO:00164772380.252
meiotic cytokinesisGO:0033206330.249
rna localizationGO:00064031150.248
regulation of cell developmentGO:00602842150.247
regulation of protein complex disassemblyGO:0043244290.244
neuroblast divisionGO:0055057350.241
negative regulation of transcription dna templatedGO:00458922370.240
Human
apoptotic processGO:00069151590.239
Human Worm
negative regulation of protein metabolic processGO:0051248850.232
Human
pronuclear migrationGO:003504640.227
positive regulation of nervous system developmentGO:0051962690.223
deathGO:00162652840.222
Human Worm
negative regulation of multicellular organismal processGO:00512411420.222
regulation of localizationGO:00328792750.221
regulation of nuclear divisionGO:0051783580.219
Human Worm
metaphase anaphase transition of cell cycleGO:0044784280.219
Human
endocytosisGO:00068973100.216
nuclear migrationGO:0007097200.215
protein complex assemblyGO:00064612000.210
gene silencingGO:00164581380.208
regulation of neuron differentiationGO:00456641030.208
regulation of phosphate metabolic processGO:00192202100.201
Human
stem cell proliferationGO:0072089880.193
programmed cell deathGO:00125012570.192
Human Worm
regulation of nervous system developmentGO:00519602480.189
protein complex disassemblyGO:0043241360.188
cell motilityGO:00488702510.187
larval developmentGO:00021641040.182
Worm
microtubule cytoskeleton organization involved in mitosisGO:1902850520.180
cellular macromolecule localizationGO:00707272200.174
protein depolymerizationGO:0051261310.169
dna packagingGO:0006323910.168
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.165
Human
single organism intracellular transportGO:19025822070.165
canonical wnt signaling pathwayGO:0060070210.163
regulation of proteolysisGO:0030162870.163
Human
negative regulation of cellular component organizationGO:00511291080.163
Human
nuclear importGO:0051170510.161
synaptonemal complex organizationGO:007019350.157
Yeast
regulation of meiotic cell cycleGO:005144590.155
Worm
neuronal stem cell divisionGO:0036445350.155
mitotic chromosome condensationGO:0007076220.154
maintenance of locationGO:0051235730.154
negative regulation of nucleobase containing compound metabolic processGO:00459342610.154
Human
regulation of wnt signaling pathwayGO:0030111680.148
developmental maturationGO:00217001720.145
regulation of cellular response to stressGO:0080135890.143
establishment or maintenance of cell polarityGO:00071631670.143
proteolysis involved in cellular protein catabolic processGO:0051603830.142
Human
regulation of protein localizationGO:0032880760.141
macromolecule catabolic processGO:00090571610.140
Human
single organism cellular localizationGO:19025801800.135
cellular response to dna damage stimulusGO:00069742230.132
Human
regulation of sister chromatid segregationGO:0033045280.131
Human
establishment of spindle orientationGO:0051294180.130
negative regulation of mitotic sister chromatid separationGO:2000816130.130
Human
neuron projection guidanceGO:00974852410.130
meiotic cell cycle phase transitionGO:004477140.129
protein phosphorylationGO:00064681690.126
cellular macromolecule catabolic processGO:00442651360.126
Human
positive regulation of mitotic cell cycleGO:0045931340.125
Human
positive regulation of cell proliferationGO:0008284470.124
axon guidanceGO:00074112330.120
regulation of phosphorus metabolic processGO:00511742100.120
Human
genitalia developmentGO:0048806260.119
Worm
positive regulation of programmed cell deathGO:0043068620.119
regulation of canonical wnt signaling pathwayGO:0060828150.114
developmental programmed cell deathGO:00106231380.113
digestive tract developmentGO:00485651490.112
immune system developmentGO:0002520570.112
wing disc morphogenesisGO:00074723440.110
regulation of transcription from rna polymerase ii promoterGO:00063573780.109
Human
negative regulation of cell divisionGO:0051782170.109
Human
germ line stem cell divisionGO:0042078250.109
macromolecular complex assemblyGO:00650032560.108
regulation of nucleocytoplasmic transportGO:0046822350.107
microtubule depolymerizationGO:0007019250.106
myofibril assemblyGO:0030239360.106
negative regulation of protein complex disassemblyGO:0043242230.103
negative regulation of microtubule depolymerizationGO:0007026210.102
female meiosis chromosome segregationGO:0016321330.101
purine nucleoside triphosphate catabolic processGO:00091461080.100
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.099
Human
regulation of catalytic activityGO:00507901850.099
Human Yeast
axon developmentGO:00615642970.098
negative regulation of mitotic cell cycle phase transitionGO:19019911030.096
Human
establishment of spindle localizationGO:0051293220.096
negative regulation of mitotic cell cycleGO:00459301090.092
Human
mitotic g2 m transition checkpointGO:0044818700.092
immune system processGO:00023763470.092
negative regulation of nucleic acid templated transcriptionGO:19035072400.092
Human
asymmetric neuroblast divisionGO:0055059330.092
appendage developmentGO:00487364010.088
regulation of cellular protein metabolic processGO:00322682430.088
Human
negative regulation of cellular protein metabolic processGO:0032269850.088
Human
dna amplificationGO:0006277110.087
nucleus localizationGO:0051647340.087
protein localizationGO:00081042840.086
epithelial cell differentiationGO:00308553220.085
maintenance of location in cellGO:0051651280.085
positive regulation of cellular catabolic processGO:0031331950.083
Human
cytoplasmic transportGO:00164821300.082
photoreceptor cell differentiationGO:00465301700.081
positive regulation of cell differentiationGO:0045597640.081
stem cell developmentGO:0048864790.081
regulation of phosphorylationGO:00423251470.080
Human
positive regulation of nucleic acid templated transcriptionGO:19035082660.079
mitotic g2 dna damage checkpointGO:0007095690.079
regulation of protein catabolic processGO:0042176550.078
Human
regulation of mitotic metaphase anaphase transitionGO:0030071260.077
Human
oocyte developmentGO:00485991240.076
cellular protein catabolic processGO:0044257830.076
Human
protein modification by small protein conjugation or removalGO:00706471060.074
Human
positive regulation of proteolysisGO:0045862520.074
Human
membrane disassemblyGO:003039740.071
Worm
regulation of cellular protein catabolic processGO:1903362440.071
Human
regulation of intracellular protein transportGO:0033157460.069
protein dna complex subunit organizationGO:0071824860.068
negative regulation of cell proliferationGO:0008285690.068
positive regulation of protein import into nucleusGO:0042307210.067
dendrite morphogenesisGO:00488131990.066
negative regulation of cell developmentGO:0010721620.066
regulation of microtubule depolymerizationGO:0031114240.065
metaphase anaphase transition of mitotic cell cycleGO:0007091280.065
Human
malpighian tubule morphogenesisGO:0007443440.065
aromatic compound catabolic processGO:00194391660.064
columnar cuboidal epithelial cell differentiationGO:00020652560.064
histoblast morphogenesisGO:000748890.063
muscle organ developmentGO:00075171270.063
compound eye morphogenesisGO:00017452490.063
establishment of organelle localizationGO:00516561220.062
positive regulation of macromolecule biosynthetic processGO:00105572830.062
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.061
Human
regulation of protein kinase activityGO:0045859510.061
Human
proteolysisGO:00065081920.060
Human
negative regulation of protein depolymerizationGO:1901880230.059
proteasomal protein catabolic processGO:0010498590.059
Human
mitotic spindle assembly checkpointGO:0007094110.059
Human
regulation of chromosome organizationGO:0033044640.059
Human
regulation of response to stressGO:00801342000.058
positive regulation of gene expressionGO:00106282900.058
negative regulation of cellular metabolic processGO:00313243820.057
Human
axonogenesisGO:00074092900.055
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.055
Human
organic substance transportGO:00717022570.054
membrane organizationGO:00610241120.054
Worm
regulation of protein modification processGO:00313991120.053
Human
mitotic cell cycle embryonicGO:0045448380.052
positive regulation of phosphorylationGO:0042327870.051
Human
mrna metabolic processGO:00160711240.051
hematopoietic or lymphoid organ developmentGO:0048534570.050
negative regulation of rna metabolic processGO:00512532510.049
Human
regulation of spindle organizationGO:0090224170.049
regulation of molecular functionGO:00650092170.049
Human Yeast
organonitrogen compound metabolic processGO:19015643180.048
dna integrity checkpointGO:0031570810.048
Human
response to radiationGO:00093141550.047
neuron recognitionGO:00080381010.047
somatic stem cell divisionGO:0048103370.047
regulation of programmed cell deathGO:00430671520.046
Human
positive regulation of transcription factor import into nucleusGO:0042993190.046
negative regulation of cell differentiationGO:00455961430.046
central nervous system developmentGO:00074172010.046
protein localization to organelleGO:0033365820.045
Human
eye developmentGO:00016543230.045
renal tubule developmentGO:0061326640.045
imaginal disc derived appendage developmentGO:00487373990.044
morphogenesis of an epitheliumGO:00020092760.044
hindgut developmentGO:0061525580.044
positive regulation of biosynthetic processGO:00098913160.044
positive regulation of catabolic processGO:00098961050.043
Human
posttranscriptional regulation of gene expressionGO:00106081450.043
Human
sensory organ precursor cell divisionGO:0045035100.042
establishment of mitotic spindle localizationGO:0040001170.042
appendage morphogenesisGO:00351073970.042
establishment of mitotic spindle orientationGO:0000132130.042
nuclear transportGO:0051169720.042
organelle localizationGO:00516401480.042
cellular catabolic processGO:00442483720.041
Human
regulation of protein localization to nucleusGO:1900180290.041
receptor mediated endocytosisGO:0006898210.041
protein import into nucleusGO:0006606510.041
regulation of dendrite developmentGO:0050773370.040
wnt signaling pathwayGO:0016055980.040
atp metabolic processGO:0046034490.040
nuclear envelope organizationGO:000699870.040
Worm
regulation of dna metabolic processGO:0051052340.040
eggshell formationGO:00307031050.040
negative regulation of cell cycle processGO:00109481090.039
Human
regulation of rac gtpase activityGO:003231410.039
ovarian follicle cell developmentGO:00307072480.039
positive regulation of response to stimulusGO:00485843230.039
regulation of protein phosphatase type 2a activityGO:003404720.038
chromosome organization involved in meiosisGO:0070192100.038
negative regulation of organelle organizationGO:0010639560.038
Human
dna metabolic processGO:00062592270.037
Yeast
negative regulation of mitotic sister chromatid segregationGO:0033048130.037
Human
positive regulation of cellular biosynthetic processGO:00313283160.037
spindle assembly involved in female meiosis iGO:000705750.037
positive regulation of cell communicationGO:00106472500.037
purine nucleoside triphosphate metabolic processGO:00091441190.037
oocyte microtubule cytoskeleton organizationGO:0016325350.037
embryonic development via the syncytial blastodermGO:00017001480.036
endomembrane system organizationGO:00102561190.036
Worm
regulation of chromatin bindingGO:003556130.035
defense responseGO:00069523000.035
negative regulation of cell cycle phase transitionGO:19019881030.035
Human
cell cycle g1 s phase transitionGO:0044843310.035
positive regulation of cell deathGO:0010942690.035
regulation of protein depolymerizationGO:1901879270.034
brain developmentGO:00074201200.034
positive regulation of mitotic cell cycle phase transitionGO:1901992200.033
Human
regulation of transferase activityGO:0051338580.033
Human
oxoacid metabolic processGO:00434361030.033
oocyte differentiationGO:00099941450.033
regulation of neuron projection developmentGO:0010975690.032
protein targeting to nucleusGO:0044744510.032
positive regulation of mitotic sister chromatid separationGO:1901970100.031
Human
digestive system developmentGO:00551231490.031
spindle localizationGO:0051653220.031
epithelial cell developmentGO:00020642740.031
negative regulation of nitrogen compound metabolic processGO:00511722650.031
Human
translationGO:0006412690.031
tube morphogenesisGO:00352391910.031
protein ubiquitinationGO:0016567700.031
Human
mitotic dna integrity checkpointGO:0044774750.030
cellular macromolecular complex assemblyGO:00346221530.030
response to endogenous stimulusGO:00097191190.030
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.030
Human
regulation of cellular component biogenesisGO:00440872010.029
positive regulation of growthGO:0045927750.029
g2 dna damage checkpointGO:0031572690.029
Human
protein localization to nucleusGO:0034504550.029
nucleocytoplasmic transportGO:0006913720.029
regulation of mitotic spindle elongationGO:003288810.029
negative regulation of metaphase anaphase transition of cell cycleGO:1902100130.029
Human
actin filament based processGO:00300292200.028
negative regulation of purine nucleotide catabolic processGO:003312210.028
actin cytoskeleton organizationGO:00300362060.028
determination of adult lifespanGO:00083401370.028
wing disc pattern formationGO:0035222660.028
regulation of catabolic processGO:00098941700.028
Human
cardiovascular system developmentGO:0072358820.028
microtubule polymerization or depolymerizationGO:0031109390.028
meiotic sister chromatid cohesionGO:005117760.027
regulation of response to dna damage stimulusGO:2001020230.027
assembly of actomyosin apparatus involved in cytokinesisGO:0000912110.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
growthGO:00400073590.026
dna damage checkpointGO:0000077780.026
Human
protein catabolic processGO:00301631010.025
Human
cellular response to oxygen containing compoundGO:1901701790.025
multicellular organismal agingGO:00102591400.025
neuronal stem cell maintenanceGO:009715040.025
eggshell chorion gene amplificationGO:000730790.025
purine ribonucleoside monophosphate metabolic processGO:0009167500.024
sensory organ morphogenesisGO:00905962600.024
chorion containing eggshell formationGO:00073041050.024
regulation of exit from mitosisGO:000709670.024
negative regulation of programmed cell deathGO:0043069720.024
Human
hindgut morphogenesisGO:0007442580.024
establishment of nucleus localizationGO:0040023260.024
regulation of microtubule polymerization or depolymerizationGO:0031110270.024
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.023
Human
protein modification by small protein conjugationGO:0032446790.023
Human
icosanoid biosynthetic processGO:004645610.023
cell fate determinationGO:0001709910.023
regulation of synapse structure and activityGO:00508031280.023
purine nucleotide metabolic processGO:00061631460.023
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.023
positive regulation of developmental growthGO:0048639620.022
embryonic axis specificationGO:00005781070.022
regulation of intracellular signal transductionGO:19025312360.022
regulation of apoptotic processGO:00429811300.022
Human
single organism biosynthetic processGO:00447112060.022
syncytial blastoderm mitotic cell cycleGO:0035186210.022
nucleotide metabolic processGO:00091171610.022
cellular nitrogen compound catabolic processGO:00442701650.022
dna dependent dna replicationGO:0006261170.021
response to organic substanceGO:00100332840.021
dna replicationGO:0006260480.021
cell proliferationGO:00082832990.021
catabolic processGO:00090564090.021
Human
purine nucleoside catabolic processGO:00061521120.021
developmental growthGO:00485892800.020
epithelial tube morphogenesisGO:0060562880.020
positive regulation of transferase activityGO:0051347260.020
Human
nucleoside triphosphate metabolic processGO:00091411200.020
mitotic dna damage checkpointGO:0044773740.020
regulation of intracellular transportGO:0032386640.020
regulation of neural precursor cell proliferationGO:2000177350.020
synaptic transmissionGO:00072682880.020
negative regulation of nervous system developmentGO:0051961920.020
positive regulation of signal transductionGO:00099672230.019
male meiosis cytokinesisGO:0007112260.019
regulation of protein import into nucleusGO:0042306280.019
macromolecule methylationGO:0043414450.019
regulation of organ morphogenesisGO:2000027780.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
cytokinetic cell separationGO:000092010.019
negative regulation of cellular catabolic processGO:0031330340.018
Human
negative regulation of meiotic cell cycleGO:005144720.018
positive regulation of cell cycleGO:0045787430.018
Human Yeast
intercellular bridge organizationGO:0043063140.018
positive regulation of catalytic activityGO:00430851180.018
Human Yeast
establishment of meiotic spindle orientationGO:005129620.018
oocyte morphogenesisGO:004860130.018
single organism membrane organizationGO:0044802930.018
Worm
microtubule anchoringGO:0034453110.018
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436190.018
Human
negative regulation of proteolysisGO:0045861310.017
Human
response to nitrogen compoundGO:1901698900.017
negative regulation of mitotic metaphase anaphase transitionGO:0045841130.017
Human
transcription from rna polymerase ii promoterGO:00063663680.017
Human
columnar cuboidal epithelial cell developmentGO:00020662490.017
positive regulation of stem cell maintenanceGO:190245910.017
sister chromatid cohesionGO:0007062180.017
cellular protein localizationGO:00346131600.016
negative regulation of nuclear divisionGO:0051784170.016
Human
centriole replicationGO:0007099240.016
chromosome movement towards spindle poleGO:005130540.016
kinetochore organizationGO:005138390.016
gland developmentGO:00487321910.016
regulation of sister chromatid cohesionGO:000706320.016
regulation of transportGO:00510491810.016
positive regulation of nucleocytoplasmic transportGO:0046824240.016
striated muscle cell developmentGO:0055002500.016
positive regulation of protein phosphorylationGO:0001934340.016
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.016
response to ionizing radiationGO:0010212320.016
tissue morphogenesisGO:00487292970.015
positive regulation of neuron differentiationGO:0045666260.015
dendrite regenerationGO:003110420.015
organic substance catabolic processGO:19015753080.015
Human
regulation of cytoplasmic transportGO:1903649470.015
organonitrogen compound catabolic processGO:19015651280.015
positive regulation of immune system processGO:0002684680.015
establishment of meiotic spindle localizationGO:005129530.015
positive regulation of cellular component organizationGO:00511301560.015
Human Yeast
positive regulation of hydrolase activityGO:0051345780.015
spindle elongationGO:0051231830.015
multi multicellular organism processGO:00447061230.014
covalent chromatin modificationGO:00165691060.014
meiotic g2 mi transitionGO:000831530.014
meiotic chromosome condensationGO:001003230.014
regulation of cytokinesisGO:003246530.014
negative regulation of catalytic activityGO:0043086420.014
Human
dna recombinationGO:0006310320.014
Yeast
regulation of protein transportGO:0051223570.014
negative regulation of response to stimulusGO:00485852580.014
circulatory system developmentGO:0072359820.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
female germ line cyst formationGO:0048135420.014
ribonucleoside monophosphate metabolic processGO:0009161510.014
vesicle mediated transportGO:00161923810.014
protein importGO:0017038550.014
purine ribonucleoside catabolic processGO:00461301120.014
taxisGO:00423303040.014
compound eye developmentGO:00487493070.014
synaptic growth at neuromuscular junctionGO:00511241190.014
cellular response to organic substanceGO:00713101320.013

polo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
nervous system diseaseDOID:86300.052
disease of cellular proliferationDOID:1456600.043
bone marrow cancerDOID:496000.026
organ system cancerDOID:005068600.026
immune system cancerDOID:006008300.026
hematologic cancerDOID:253100.026
cancerDOID:16200.026