IMP: Integrative Multi-species Prediction

Drosophila melanogaster

226 known processes

Nc (Dmel_CG8091)

Nedd2-like caspase

(Aliases: Nc\Dronc,dronc,caspase-9,anon-EST:GressD6,anon-EST:GreesD6,Dronc/Casp9,anon-WO0118547.313,Dronc,CG8091,CG8090,Dmel\CG8091,DRONC)

FLYBASE: FBgn0026404
Entrez: 39173
UniProtKB: Q9XYF4

Process Predictions
Disease Predictions

Nc biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
positive regulation of endopeptidase activity	GO:0010950	26	0.856
humoral immune response	GO:0006959	117	0.785	Fly
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.736
tissue death	GO:0016271	102	0.629
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.626
regulation of retinal cell programmed cell death	GO:0046668	18	0.620
developmental programmed cell death	GO:0010623	138	0.610
histolysis	GO:0007559	102	0.537
sperm individualization	GO:0007291	48	0.514
male gamete generation	GO:0048232	201	0.507
positive regulation of peptidase activity	GO:0010952	29	0.490
spermatogenesis	GO:0007283	200	0.480
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.479
salivary gland development	GO:0007431	162	0.476
defense response	GO:0006952	300	0.458
gland morphogenesis	GO:0022612	145	0.443
positive regulation of retinal cell programmed cell death	GO:0046670	9	0.439
salivary gland morphogenesis	GO:0007435	145	0.381
retinal cell programmed cell death	GO:0046666	25	0.381
regulation of organ morphogenesis	GO:2000027	78	0.368
regulation of anatomical structure morphogenesis	GO:0022603	242	0.367
execution phase of apoptosis	GO:0097194	7	0.353	Worm Fly
regulation of compound eye retinal cell programmed cell death	GO:0046669	18	0.350
dendrite development	GO:0016358	204	0.342
spermatid differentiation	GO:0048515	114	0.334
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.329
positive regulation of proteolysis	GO:0045862	52	0.320
compound eye development	GO:0048749	307	0.310
autophagic cell death	GO:0048102	83	0.282
negative regulation of response to stimulus	GO:0048585	258	0.270
regulation of humoral immune response	GO:0002920	51	0.263	Fly
regulation of endopeptidase activity	GO:0052548	36	0.263
protein complex assembly	GO:0006461	200	0.256
salivary gland cell autophagic cell death	GO:0035071	83	0.239
gland development	GO:0048732	191	0.238
peptidoglycan recognition protein signaling pathway	GO:0061057	16	0.231	Fly
regulation of protein metabolic process	GO:0051246	256	0.231
positive regulation of compound eye retinal cell programmed cell death	GO:0046672	9	0.225
immune response	GO:0006955	246	0.223
compound eye morphogenesis	GO:0001745	249	0.222
salivary gland histolysis	GO:0035070	88	0.219
negative regulation of signaling	GO:0023057	219	0.218	Fly
positive regulation of protein metabolic process	GO:0051247	128	0.218
exocrine system development	GO:0035272	162	0.212
proteolysis	GO:0006508	192	0.212
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.207
secondary metabolic process	GO:0019748	75	0.205
protein complex biogenesis	GO:0070271	201	0.204
macromolecular complex assembly	GO:0065003	256	0.204
response to ionizing radiation	GO:0010212	32	0.203	Fly
sensory organ morphogenesis	GO:0090596	260	0.201
response to extracellular stimulus	GO:0009991	116	0.200	Fly
organonitrogen compound metabolic process	GO:1901564	318	0.196	Fly
protein k48 linked ubiquitination	GO:0070936	3	0.194
cell death	GO:0008219	279	0.189
phenol containing compound metabolic process	GO:0018958	57	0.189
compound eye retinal cell programmed cell death	GO:0046667	23	0.185
cellular catabolic process	GO:0044248	372	0.184
programmed cell death	GO:0012501	257	0.182
apoptotic process	GO:0006915	159	0.181
eye morphogenesis	GO:0048592	260	0.178
eye development	GO:0001654	323	0.176
protein maturation	GO:0051604	71	0.172
catabolic process	GO:0009056	409	0.141
response to radiation	GO:0009314	155	0.139	Fly
zymogen activation	GO:0031638	20	0.137
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.136
positive regulation of response to stimulus	GO:0048584	323	0.131
immune system process	GO:0002376	347	0.129
peptide metabolic process	GO:0006518	80	0.126	Fly
cellular amino acid metabolic process	GO:0006520	61	0.126
imaginal disc derived appendage development	GO:0048737	399	0.125
positive regulation of cellular protein metabolic process	GO:0032270	118	0.124
positive regulation of response to biotic stimulus	GO:0002833	31	0.123	Fly
nurse cell apoptotic process	GO:0045476	17	0.122
organic substance catabolic process	GO:1901575	308	0.121	Worm
regulation of catabolic process	GO:0009894	170	0.119
regulation of peptidase activity	GO:0052547	39	0.118
regulation of proteolysis	GO:0030162	87	0.118
spermatid development	GO:0007286	98	0.117
melanin metabolic process	GO:0006582	47	0.112
regulation of cell development	GO:0060284	215	0.110
positive regulation of macromolecule metabolic process	GO:0010604	405	0.110
apoptotic process involved in development	GO:1902742	20	0.105
positive regulation of programmed cell death	GO:0043068	62	0.104
regulation of programmed cell death	GO:0043067	152	0.104
imaginal disc derived wing morphogenesis	GO:0007476	337	0.103
cellular response to extracellular stimulus	GO:0031668	64	0.102	Fly
positive regulation of macroautophagy	GO:0016239	8	0.102	Fly
death	GO:0016265	284	0.101
response to biotic stimulus	GO:0009607	294	0.100	Mouse Fly
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.100
embryonic morphogenesis	GO:0048598	206	0.095
positive regulation of developmental process	GO:0051094	143	0.095
carboxylic acid metabolic process	GO:0019752	92	0.094
protein processing	GO:0016485	68	0.093
positive regulation of signal transduction	GO:0009967	223	0.092
dendrite morphogenesis	GO:0048813	199	0.091
defense response to bacterium	GO:0042742	178	0.091	Fly
melanization defense response	GO:0035006	45	0.091
antibacterial peptide biosynthetic process	GO:0002780	22	0.088	Fly
appendage morphogenesis	GO:0035107	397	0.087
positive regulation of antibacterial peptide biosynthetic process	GO:0006963	20	0.086	Fly
macromolecule catabolic process	GO:0009057	161	0.086	Worm
cellularization	GO:0007349	90	0.084
positive regulation of cell communication	GO:0010647	250	0.084
cellular macromolecule catabolic process	GO:0044265	136	0.082
regulation of apoptotic process	GO:0042981	130	0.081
forebrain development	GO:0030900	2	0.081
epithelial cell migration	GO:0010631	148	0.080
nuclear division	GO:0000280	332	0.080
positive regulation of cell death	GO:0010942	69	0.079
asymmetric cell division	GO:0008356	37	0.077
regulation of apoptotic signaling pathway	GO:2001233	10	0.076
response to external biotic stimulus	GO:0043207	293	0.075	Mouse Fly
epithelial cell development	GO:0002064	274	0.075
autophagy	GO:0006914	108	0.075
antimicrobial peptide production	GO:0002775	46	0.075	Fly
regulation of dna metabolic process	GO:0051052	34	0.075
positive regulation of multicellular organismal process	GO:0051240	143	0.074
positive regulation of signaling	GO:0023056	243	0.073
developmental maturation	GO:0021700	172	0.073
antimicrobial humoral response	GO:0019730	99	0.073	Fly
cell type specific apoptotic process	GO:0097285	38	0.073
organelle fission	GO:0048285	340	0.071
pigment metabolic process	GO:0042440	84	0.068
appendage development	GO:0048736	401	0.067
neuromuscular synaptic transmission	GO:0007274	67	0.067	Fly
s adenosylmethionine cycle	GO:0033353	3	0.067
embryonic development via the syncytial blastoderm	GO:0001700	148	0.065
brain development	GO:0007420	120	0.064
protein heterooligomerization	GO:0051291	4	0.063
anatomical structure homeostasis	GO:0060249	97	0.062
protein modification by small protein conjugation or removal	GO:0070647	106	0.061
regulation of multicellular organismal development	GO:2000026	414	0.061
regulation of molecular function	GO:0065009	217	0.060
establishment of localization in cell	GO:0051649	402	0.060	Mouse
biosynthetic process of antibacterial peptides active against gram negative bacteria	GO:0002812	14	0.059	Fly
synaptic transmission	GO:0007268	288	0.057	Fly
positive regulation of molecular function	GO:0044093	136	0.056
positive regulation of humoral immune response	GO:0002922	28	0.056	Fly
regulation of cellular catabolic process	GO:0031329	157	0.056
regulation of execution phase of apoptosis	GO:1900117	5	0.055
response to starvation	GO:0042594	97	0.055	Fly
sulfur compound metabolic process	GO:0006790	59	0.053
localization of cell	GO:0051674	257	0.052
positive regulation of cellular biosynthetic process	GO:0031328	316	0.052	Fly
single organism catabolic process	GO:0044712	228	0.052	Fly
defense response to virus	GO:0051607	23	0.050	Fly
wnt signaling pathway	GO:0016055	98	0.050
antibacterial humoral response	GO:0019731	44	0.049	Fly
cellular component disassembly	GO:0022411	46	0.049
regulation of cellular protein metabolic process	GO:0032268	243	0.048
central nervous system development	GO:0007417	201	0.048
apoptotic signaling pathway	GO:0097190	27	0.048
organonitrogen compound biosynthetic process	GO:1901566	117	0.047	Fly
glycosyl compound metabolic process	GO:1901657	127	0.046
regulation of defense response to bacterium	GO:1900424	30	0.044	Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.043	Fly
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.043	Fly
cellular modified amino acid metabolic process	GO:0006575	45	0.042
positive regulation of antimicrobial peptide biosynthetic process	GO:0002807	26	0.041	Fly
homeostatic process	GO:0042592	199	0.040
head involution	GO:0008258	35	0.040
regulation of response to external stimulus	GO:0032101	115	0.040	Mouse Fly
antennal morphogenesis	GO:0048800	14	0.039
defense response to gram negative bacterium	GO:0050829	94	0.039	Fly
cellular response to sterol depletion	GO:0071501	3	0.039	Fly
ovarian follicle cell development	GO:0030707	248	0.039
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.039	Fly
antibacterial peptide production	GO:0002778	22	0.038	Fly
carbohydrate derivative metabolic process	GO:1901135	217	0.037
wing disc morphogenesis	GO:0007472	344	0.037
positive regulation of hydrolase activity	GO:0051345	78	0.037
positive regulation of production of molecular mediator of immune response	GO:0002702	28	0.036	Fly
positive regulation of antibacterial peptide production	GO:0002803	20	0.036	Fly
response to abiotic stimulus	GO:0009628	341	0.036	Human Mouse Fly
organonitrogen compound catabolic process	GO:1901565	128	0.036
nucleobase containing small molecule metabolic process	GO:0055086	174	0.035
defense response to other organism	GO:0098542	225	0.035	Fly
positive regulation of response to external stimulus	GO:0032103	44	0.035	Fly
cellular protein modification process	GO:0006464	438	0.035
protein modification process	GO:0036211	438	0.035
protein ubiquitination	GO:0016567	70	0.034
cellular response to external stimulus	GO:0071496	66	0.033	Human Fly
regulation of cell differentiation	GO:0045595	302	0.033
positive regulation of antimicrobial humoral response	GO:0002760	28	0.033	Fly
amide biosynthetic process	GO:0043604	42	0.032	Fly
ribonucleoside metabolic process	GO:0009119	127	0.032
purine ribonucleoside metabolic process	GO:0046128	127	0.032
intracellular transport	GO:0046907	228	0.031
regulation of catalytic activity	GO:0050790	185	0.031
peptide biosynthetic process	GO:0043043	42	0.031	Fly
positive regulation of immune effector process	GO:0002699	28	0.031	Fly
transcription from rna polymerase ii promoter	GO:0006366	368	0.031
small molecule metabolic process	GO:0044281	305	0.031
purine containing compound metabolic process	GO:0072521	155	0.030
chemical homeostasis	GO:0048878	92	0.030
cell division	GO:0051301	248	0.030
response to bacterium	GO:0009617	198	0.030	Mouse Fly
tissue migration	GO:0090130	155	0.030
organic acid catabolic process	GO:0016054	16	0.030
positive regulation of response to nutrient levels	GO:0032109	8	0.030	Fly
regulation of cell shape	GO:0008360	113	0.030
chromosome segregation	GO:0007059	157	0.029
organic hydroxy compound metabolic process	GO:1901615	83	0.029
post embryonic appendage morphogenesis	GO:0035120	385	0.029
aromatic compound catabolic process	GO:0019439	166	0.029
activation of cysteine type endopeptidase activity	GO:0097202	17	0.028
response to organic substance	GO:0010033	284	0.028	Human Mouse
regulation of production of molecular mediator of immune response	GO:0002700	44	0.028	Fly
purine nucleoside metabolic process	GO:0042278	127	0.028
positive regulation of rna biosynthetic process	GO:1902680	266	0.028	Fly
response to virus	GO:0009615	28	0.028	Fly
cell motility	GO:0048870	251	0.027
epithelial cell differentiation	GO:0030855	322	0.027
negative regulation of multicellular organismal process	GO:0051241	142	0.027
spindle organization	GO:0007051	253	0.027
regulation of multi organism process	GO:0043900	131	0.026	Fly
cellular protein catabolic process	GO:0044257	83	0.026
meiotic cell cycle	GO:0051321	171	0.026
organic cyclic compound catabolic process	GO:1901361	168	0.026
regulation of response to stress	GO:0080134	200	0.026	Mouse Fly
nucleobase containing compound catabolic process	GO:0034655	165	0.025
positive regulation of antimicrobial peptide production	GO:0002225	28	0.025	Fly
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.025	Fly
embryo development ending in birth or egg hatching	GO:0009792	152	0.025
protein oligomerization	GO:0051259	16	0.025
synaptic growth at neuromuscular junction	GO:0051124	119	0.025
regulation of wnt signaling pathway	GO:0030111	68	0.025
cell migration	GO:0016477	238	0.025
regulation of nervous system development	GO:0051960	248	0.025
negative regulation of signal transduction	GO:0009968	206	0.025
cellular nitrogen compound catabolic process	GO:0044270	165	0.025
regulation of hydrolase activity	GO:0051336	97	0.025
meiotic nuclear division	GO:0007126	151	0.024
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.024
protein modification by small protein conjugation	GO:0032446	79	0.024
positive regulation of gene expression	GO:0010628	290	0.024	Fly
single organism biosynthetic process	GO:0044711	206	0.024
er nucleus signaling pathway	GO:0006984	9	0.024	Mouse Fly
positive regulation of defense response	GO:0031349	59	0.023	Fly
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.023	Fly
positive regulation of rna metabolic process	GO:0051254	271	0.023	Fly
response to nutrient levels	GO:0031667	114	0.023	Fly
response to other organism	GO:0051707	293	0.023	Mouse Fly
epithelium migration	GO:0090132	148	0.023
response to gamma radiation	GO:0010332	17	0.022
peripheral nervous system development	GO:0007422	52	0.022	Fly
regulation of response to biotic stimulus	GO:0002831	63	0.022	Fly
eye antennal disc morphogenesis	GO:0007455	34	0.022
cellular amide metabolic process	GO:0043603	80	0.022	Fly
neuron death	GO:0070997	27	0.022
regulation of protein modification process	GO:0031399	112	0.022
regulation of antimicrobial peptide biosynthetic process	GO:0002805	38	0.021	Fly
neuron remodeling	GO:0016322	29	0.021
endocytosis	GO:0006897	310	0.021	Worm
immune effector process	GO:0002252	98	0.021	Fly
negative regulation of organelle organization	GO:0010639	56	0.021
multi organism behavior	GO:0051705	175	0.021
negative regulation of programmed cell death	GO:0043069	72	0.021	Fly
regulation of defense response	GO:0031347	102	0.021	Mouse Fly
border follicle cell migration	GO:0007298	113	0.021
ovarian follicle cell migration	GO:0007297	121	0.021
response to x ray	GO:0010165	8	0.020	Fly
regulation of macroautophagy	GO:0016241	15	0.020	Fly
regulation of response to extracellular stimulus	GO:0032104	18	0.020	Fly
ameboidal type cell migration	GO:0001667	151	0.020
chromatin organization	GO:0006325	207	0.020
cytoskeleton dependent cytokinesis	GO:0061640	81	0.020
lateral inhibition	GO:0046331	206	0.020
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
hemocyte differentiation	GO:0042386	38	0.019
head development	GO:0060322	135	0.019
small molecule catabolic process	GO:0044282	21	0.019
chromosome organization	GO:0051276	360	0.019
positive regulation of autophagy	GO:0010508	21	0.019	Fly
vesicle mediated transport	GO:0016192	381	0.019	Worm
cellular response to starvation	GO:0009267	61	0.019	Fly
axis specification	GO:0009798	167	0.019
photoreceptor cell differentiation	GO:0046530	170	0.019
chaeta morphogenesis	GO:0008407	42	0.019
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.018	Fly
cellular ketone metabolic process	GO:0042180	24	0.018
positive regulation of transcription dna templated	GO:0045893	266	0.018	Fly
cellular response to organic substance	GO:0071310	132	0.018	Human Mouse
phagocytosis	GO:0006909	215	0.018	Worm
regulation of transport	GO:0051049	181	0.018	Mouse
modification dependent macromolecule catabolic process	GO:0043632	79	0.018
mitotic spindle organization	GO:0007052	220	0.018
endomembrane system organization	GO:0010256	119	0.018
regulation of chromosome organization	GO:0033044	64	0.018
morphogenesis of an epithelium	GO:0002009	276	0.018
regulation of response to nutrient levels	GO:0032107	18	0.017	Fly
skeletal muscle fiber development	GO:0048741	3	0.017
positive regulation of cellular catabolic process	GO:0031331	95	0.017	Fly
antennal development	GO:0007469	25	0.017
eye photoreceptor cell differentiation	GO:0001754	145	0.017
positive regulation of multi organism process	GO:0043902	40	0.017	Fly
gonad development	GO:0008406	50	0.016
positive regulation of cell development	GO:0010720	61	0.016
multicellular organismal aging	GO:0010259	140	0.016
negative regulation of immune response	GO:0050777	39	0.016
negative regulation of cell differentiation	GO:0045596	143	0.016
male meiosis	GO:0007140	52	0.016
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.016
cellular homeostasis	GO:0019725	80	0.015
negative regulation of cellular component organization	GO:0051129	108	0.015
respiratory system development	GO:0060541	213	0.015
chemosensory behavior	GO:0007635	106	0.015
meiotic cell cycle process	GO:1903046	132	0.015
regulation of cell proliferation	GO:0042127	163	0.015
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.015
heterocycle catabolic process	GO:0046700	166	0.015
photoreceptor cell development	GO:0042461	96	0.015
regulation of cell death	GO:0010941	173	0.015
protein localization	GO:0008104	284	0.015	Mouse
ubiquitin dependent protein catabolic process	GO:0006511	78	0.015
negative regulation of biosynthetic process	GO:0009890	277	0.015
eye photoreceptor cell development	GO:0042462	81	0.015
ras protein signal transduction	GO:0007265	88	0.015
antimicrobial peptide biosynthetic process	GO:0002777	38	0.015	Fly
organic acid metabolic process	GO:0006082	103	0.014
regulation of cell morphogenesis	GO:0022604	163	0.014
negative regulation of compound eye retinal cell programmed cell death	GO:0046673	7	0.014
body morphogenesis	GO:0010171	2	0.014
regulation of antimicrobial peptide production	GO:0002784	44	0.014	Fly
maintenance of location	GO:0051235	73	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
negative regulation of protein metabolic process	GO:0051248	85	0.014
chorion containing eggshell formation	GO:0007304	105	0.014
cell maturation	GO:0048469	144	0.014
response to oxygen containing compound	GO:1901700	200	0.014	Mouse
chaeta development	GO:0022416	97	0.014
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.014
proteasomal protein catabolic process	GO:0010498	59	0.014
regulation of epithelial cell proliferation	GO:0050678	4	0.014
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.013
digestive tract morphogenesis	GO:0048546	127	0.013
establishment of vesicle localization	GO:0051650	51	0.013
regulation of immune effector process	GO:0002697	52	0.013	Fly
single organism cellular localization	GO:1902580	180	0.013
modification dependent protein catabolic process	GO:0019941	78	0.013
dna catabolic process	GO:0006308	16	0.013
single organism behavior	GO:0044708	391	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
tissue morphogenesis	GO:0048729	297	0.013
olfactory behavior	GO:0042048	97	0.013
alpha amino acid metabolic process	GO:1901605	20	0.013
oxoacid metabolic process	GO:0043436	103	0.013
striated muscle cell differentiation	GO:0051146	90	0.013
eye antennal disc development	GO:0035214	60	0.012
eggshell formation	GO:0030703	105	0.012
organelle assembly	GO:0070925	198	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
compound eye photoreceptor cell differentiation	GO:0001751	140	0.012
neuron maturation	GO:0042551	31	0.012
lipid homeostasis	GO:0055088	33	0.012
regulation of synapse assembly	GO:0051963	94	0.012
digestive tract development	GO:0048565	149	0.012
response to light stimulus	GO:0009416	124	0.012
negative regulation of developmental process	GO:0051093	201	0.012
regulation of cellular amino acid metabolic process	GO:0006521	0	0.012
cellular response to nutrient levels	GO:0031669	62	0.012	Fly
positive regulation of intracellular signal transduction	GO:1902533	116	0.012	Human Mouse
triglyceride homeostasis	GO:0070328	18	0.012
nucleoside metabolic process	GO:0009116	127	0.012
translation	GO:0006412	69	0.012
cellular component assembly involved in morphogenesis	GO:0010927	151	0.012
camera type eye development	GO:0043010	4	0.012
positive regulation of biosynthetic process	GO:0009891	316	0.012	Fly
cellular protein localization	GO:0034613	160	0.012
regulation of chromatin organization	GO:1902275	32	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
regulation of cellular amide metabolic process	GO:0034248	39	0.012	Fly
mapk cascade	GO:0000165	107	0.012
eye pigmentation	GO:0048069	43	0.011
muscle cell differentiation	GO:0042692	103	0.011
positive regulation of catabolic process	GO:0009896	105	0.011	Fly
vesicle localization	GO:0051648	55	0.011
acylglycerol homeostasis	GO:0055090	19	0.011
regulation of immune response	GO:0050776	118	0.011	Fly
intracellular protein transport	GO:0006886	104	0.011
regulation of growth	GO:0040008	233	0.011
innate immune response	GO:0045087	144	0.011
developmental pigmentation	GO:0048066	68	0.011
columnar cuboidal epithelial cell development	GO:0002066	249	0.011
protein catabolic process	GO:0030163	101	0.011	Worm
mitotic dna integrity checkpoint	GO:0044774	75	0.011	Human
cellular response to chemical stimulus	GO:0070887	199	0.011	Human Mouse
reproductive system development	GO:0061458	74	0.011
neuron apoptotic process	GO:0051402	17	0.011
negative regulation of cellular biosynthetic process	GO:0031327	277	0.011
negative regulation of cell development	GO:0010721	62	0.011
establishment of protein localization	GO:0045184	163	0.011	Mouse
cilium morphogenesis	GO:0060271	39	0.010
negative regulation of cell death	GO:0060548	81	0.010	Fly
cellular protein complex assembly	GO:0043623	71	0.010
interspecies interaction between organisms	GO:0044419	16	0.010
secretion by cell	GO:0032940	101	0.010	Mouse
microtubule based transport	GO:0010970	42	0.010
compound eye photoreceptor development	GO:0042051	78	0.010
tube morphogenesis	GO:0035239	191	0.010
notch signaling pathway	GO:0007219	120	0.010
acetylcholine metabolic process	GO:0008291	2	0.010
taxis	GO:0042330	304	0.010
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.010
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
male sex differentiation	GO:0046661	25	0.010
positive regulation of innate immune response	GO:0045089	38	0.010	Fly

Nc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.031
musculoskeletal system disease	DOID:17	0.010
cardiovascular system disease	DOID:1287	0.010

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network